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Yamaguchi MIkiyo  山口 幹代

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YAMAGUCHI Mikiyo  山口 幹代

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Researcher Number 30523089
Other IDs
Affiliation (based on the past Project Information) *help 2022 – 2023: 大阪大学, 大学院歯学研究科, 招へい教員
2021: 大阪大学, 歯学研究科, 招へい教員
2020: 大阪大学, 歯学研究科, 特任研究員
2017 – 2018: 大阪大学, 歯学研究科, 特任研究員
2016 – 2017: 大阪大学, 歯学研究科, 助教 … More
2015: 大阪大学, 歯学研究科(研究院), 助教
2014: 大阪大学, 歯学部付属病院, 医員
2009 – 2014: Osaka University, 歯学部附属病院, 医員 Less
Review Section/Research Field
Principal Investigator
Conservative dentistry / Basic Section 57030:Conservative dentistry-related
Except Principal Investigator
Conservative dentistry / Basic Section 57030:Conservative dentistry-related
Keywords
Principal Investigator
バイオフィルム / バイオフィルムの能動的脱離 / 歯性菌血症 / デンタルバイオフィルム / 根尖性歯周炎 / シーケンス解析 / 口腔内細菌叢 / 難治性根尖性歯周炎 / ポリフィロモナス ジンジバリス / 抗菌薬感受性 … More / ポルフィロモナス ジンジバリス / 薬剤排出ポンプ / 抗菌薬抵抗性 / ポルフィロモナスジンジバリス / クロルヘキシジン / 共焦点レーザー顕微鏡 / ホリフィロモナスジンジバリス / 透過型電子顕微鏡 / 走査型電子顕微鏡 / 塩化セチルピリジニウム / グルコン酸クロルヘキシジン / Porphyromonas gingivalis / 菌体外マトリックス / ポルフィロモナス ジンジバリス / 抗菌剤 / 歯学 … More
Except Principal Investigator
バイオフィルム / 細菌 / 歯学 / 免疫学 / 微生物学 / 口腔細菌学 / リアルタイムPCR / 病理組織学的観察 / EMAT / 電磁波照射 / 感染根管治療 / リアルタイムPCR / マイクロCT / 創傷の治癒 / 高周波根尖療法 / 電磁波 / 免疫組織化学 / ラット / マイクロエンドモデル / Fish法 / Fish法 / ハイドロキシアパタイト / 抗バイオフィルム薬 / 16S rRNA遺伝子解析 / 共焦点レーザー顕微鏡 / ハイドロキイアパタイト / メタゲノム解析 / in situ / デンタルバイオフィルム / オートインデューサー / Sub-MIC / アジスロマイシン / クオラムセンシング / 抗菌薬 / 難治性根尖性歯周炎 / Porphyromonas gingivalis / 抗生物質 / マクロライド / 歯周炎 / 歯内療法学 Less
  • Research Projects

    (9 results)
  • Research Products

    (35 results)
  • Co-Researchers

    (19 People)
  •  Comprehensive analysis of host signaling infected by periodontopathogenic bacteria.

    • Principal Investigator
      大嶋 淳
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57030:Conservative dentistry-related
    • Research Institution
      Osaka University
  •  The mechanism of active biofilm dispersal associated with odontogenic bacteremiaPrincipal Investigator

    • Principal Investigator
      Yamaguchi MIkiyo
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57030:Conservative dentistry-related
    • Research Institution
      Osaka University
  •  Association of the onset of refractory periapical periodontitis with oral microbiotaPrincipal Investigator

    • Principal Investigator
      Yamaguchi Mikiyo
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Conservative dentistry
    • Research Institution
      Osaka University
  •  Establishment of micro-endodontic model in small animal and development of root canal treatment tschnique and root canal treatment drugs

    • Principal Investigator
      NOIRI Yuichiro
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Conservative dentistry
    • Research Institution
      Niigata University
      Osaka University
  •  Role of multidrug efflux pumps on Porphyromonas gingivalis biofilmPrincipal Investigator

    • Principal Investigator
      Yamaguchi Mikiyo
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Conservative dentistry
    • Research Institution
      Osaka University
  •  Comprehensive in situ analysis of dental biofilm formation and control

    • Principal Investigator
      EBISU Shigeyuki
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Conservative dentistry
    • Research Institution
      Osaka University
  •  Analysis of residual Porphyromonas gingivalis biofilms in vitroaftertreatment with antibioticPrincipal Investigator

    • Principal Investigator
      YAMAGUCHI Mikiyo
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Conservative dentistry
    • Research Institution
      Osaka University
  •  A study on antibiotic resistance of Porphyromonas gingivalis biofilmPrincipal Investigator

    • Principal Investigator
      YAMAGUCHI Mikiyo
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Conservative dentistry
    • Research Institution
      Osaka University
  •  Effects of macrolides on Porphyromonas gingivalis biofolms

    • Principal Investigator
      UEDA Mio
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Conservative dentistry
    • Research Institution
      Osaka University

All 2018 2017 2015 2014 2013 2012 2011 2010 2009 2007 Other

All Journal Article Presentation Book

  • [Book] 根尖病変 治癒へ向けた戦略を究める2013

    • Author(s)
      山口幹代、野杁由一郎、
    • Total Pages
      12
    • Publisher
      ヒョーロン・パブリッシャーズ
    • Data Source
      KAKENHI-PROJECT-25861798
  • [Book] 根尖病変 治癒に向けた戦略を究める2013

    • Author(s)
      山口幹代, 野杁由一郎
    • Publisher
      ヒョーロン・パブリッシャーズ
    • Data Source
      KAKENHI-PROJECT-23792171
  • [Book] 高齢者の肺炎~治療・リハビリテーション・予防~II(1.高齢者の肺炎原因微生物と口腔内衛生状況1)口腔内細菌と誤嚥性肺炎)2011

    • Author(s)
      山口幹代, ら
    • Publisher
      医薬ジャーナル社
    • Data Source
      KAKENHI-PROJECT-21890133
  • [Book] 高齢者の肺炎~治療・リハビリテーション・予防~II2011

    • Author(s)
      山口幹代、恵比須繁之
    • Publisher
      医薬ジャーナル社
    • Data Source
      KAKENHI-PROJECT-21890133
  • [Journal Article] Factors that cause endodontic failures in general practices in Japan2018

    • Author(s)
      Mikiyo Yamaguchi, Yuichiro Noiri, Yoshihiro Itoh, Sungo Komichi, Kyoko Yagi, Reo Uemura, Haruna Naruse, Saori Matsui, Nanako Kuriki, Mikako Hayashi and Shigeyuki Ebisu
    • Journal Title

      BMC Oral Health

      Volume: -

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K11548
  • [Journal Article] Factors that cause endodontic failures in general practices in Japan.2018

    • Author(s)
      Yamaguchi M, Noiri Y, Itoh Y, Komichi S, Yagi K, Uemura R, Naruse H, Matsui S, Kuriki N, Hayashi M, Ebisu S
    • Journal Title

      BMC Oral Health.

      Volume: 18(1) Issue: 1 Pages: 70-70

    • DOI

      10.1186/s12903-018-0530-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K17062, KAKENHI-PROJECT-17H04384, KAKENHI-PROJECT-16K11548
  • [Journal Article] Investigation on Effective Education Methods for Preparing Curved Root Canals with FKG RaCe2017

    • Author(s)
      山口幹代, 伊藤勇紀, 須崎尚子, 堅田千裕, 外園真規, 川西雄三, 増田晃一, 伊藤善博, 米田直道, 岡本基岐, 朝日陽子, 山田朋美, 伊藤祥作, 林 美加子
    • Journal Title

      The Japanese Journal of Conservative Dentistry

      Volume: 60 Issue: 5 Pages: 255-261

    • DOI

      10.11471/shikahozon.60.255

    • NAID

      130006191148

    • ISSN
      0387-2343, 2188-0808
    • Language
      Japanese
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K11548
  • [Journal Article] Inhibition of polysaccharide synthesis by the sinR orthologue PGN_0088 is indirectly associated with the penetration of Porphyromonas gingivalis biofilms by macrolide antibiotics.2015

    • Author(s)
      Yamamoto R, Noiri Y, Yamaguchi M, Asahi Y, Maezono H, Ebisu S, Hayashi M
    • Journal Title

      Microbiology

      Volume: 161 Issue: 2 Pages: 422-429

    • DOI

      10.1099/mic.0.000013

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25861798, KAKENHI-PROJECT-26462878, KAKENHI-PROJECT-26861593
  • [Journal Article] Effects of the tea catechin epigallocatechin gallate on Porphyromonas gingivalis biofilms2014

    • Author(s)
      Asahi Y. et al.
    • Journal Title

      Jouranl of Applied Microbiology

      Volume: 116 Issue: 5 Pages: 1164-1171

    • DOI

      10.1111/jam.12458

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390424, KAKENHI-PROJECT-24390425, KAKENHI-PROJECT-24792020, KAKENHI-PROJECT-25450103, KAKENHI-PROJECT-25462957, KAKENHI-PROJECT-25861796, KAKENHI-PROJECT-25861798, KAKENHI-PROJECT-26462878
  • [Journal Article] Porphyromonas gingivalis biofilms persist after chlorhexidine treatment2013

    • Author(s)
      Mikiyo Yamaguchi, Yuichiro Noiri, Masae Kuboniwa, Reiko Yamamoto, Yoko Asahi, Hazuki Maezono, Mikako Hayashi, Shigeyuki Ebisu
    • Journal Title

      European Journal of Oral Sciences.

      Volume: 121 Pages: 162-168

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23792171
  • [Journal Article] Porphyromonas gingivalis biofilms persist after chlorhexidine treatment2013

    • Author(s)
      Yamaguchi M, Noiri Y, Kuboniwa M, Yamamoto R, Asahi Y, Maezono H, Hayashi M, Ebisu S
    • Journal Title

      Eur J Oral Sci

      Volume: Vol.121 Issue: 3pt1 Pages: 162-8

    • DOI

      10.1111/eos.12050

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23890103, KAKENHI-PROJECT-24390425, KAKENHI-PROJECT-24593150, KAKENHI-PROJECT-24792020, KAKENHI-PROJECT-25293387, KAKENHI-PROJECT-25861796
  • [Journal Article] Porphyromonas gingivalis biofilms persist after chlorhexidine treatment2013

    • Author(s)
      Mikiyo Yamaguchi
    • Journal Title

      European Journal of Oral Sciences

      Volume: 未定

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23792171
  • [Journal Article] 根尖孔外バイオフィルムと根尖性歯周炎の難治化2012

    • Author(s)
      山口幹代, 野杁由一郎
    • Journal Title

      日本歯科評論

      Volume: 72 Pages: 41-50

    • Data Source
      KAKENHI-PROJECT-23792171
  • [Journal Article] 根管治療を再考するーその成功と失敗の鍵ー2011

    • Author(s)
      野杁由一郎, 山口幹代, 林 美加子, 恵比須繁之
    • Journal Title

      日歯内療誌

      Volume: 32 Pages: 87-96

    • NAID

      10029089649

    • Data Source
      KAKENHI-PROJECT-23792171
  • [Journal Article] Porphyromonas gingivalisのバイオフィルムに対するクロルヘキシジンの影響2011

    • Author(s)
      山口幹代, 野杁由一郎, 久保庭雅恵, 山本れいこ, 前薗葉月, 朝日陽子, 呉本勝隆 , 恵比須繁之
    • Journal Title

      Bacterial Adherence & Biofilm

      Volume: 25 Pages: 53-58

    • Data Source
      KAKENHI-PROJECT-23792171
  • [Journal Article] Porphyromonas ginigvalisのバイオフィルムに対するクロルヘキシジンの影響2011

    • Author(s)
      山口幹代、野杁由一郎、久保庭雅恵、山本れいこ、前薗葉月、朝日陽子、呉本勝隆、恵比須繁之
    • Journal Title

      Bacterial Adherence & Biofilm

      Volume: Vol.25 Pages: 53-58

    • Data Source
      KAKENHI-PROJECT-23792171
  • [Journal Article] A Porphyromo nas gingivais mutant defective in a putative glycosyltransferase exhibits defective biosynthesis of the polysac charide portions of lipopolysacharide, decreased gingipain activities, strong autoaggregation, and increased biofilm formation.2010

    • Author(s)
      Mikiyo Yamaguchi, Keiko Sato, Hideharu Yukitake, Yuichiro Noiri, Shigeyuki Ebisu, Koji Nakayama
    • Journal Title

      Infection and Immunity. 78

      Pages: 3801-3812

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21890133
  • [Journal Article] A Porphyromonas gingivalis mutant defective in a putative glycosyltransferase exhibits defective biosynthesis of the polysaccharide portions of lipopolysaccharide, decreased gingipain activities strong autoaggregation, and increased biofilm formation2010

    • Author(s)
      YAMAGUCHI MIKIYO, et al.
    • Journal Title

      Infection and Immunity

      Volume: VOL78 Pages: 3801-3812

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21890133
  • [Journal Article] 口腔内のメーン感染源~オーラルバイオフィルム~2009

    • Author(s)
      山口幹代
    • Journal Title

      医薬ジャーナル Vol.45

      Pages: 71-76

    • Data Source
      KAKENHI-PROJECT-21890133
  • [Journal Article] 各種抗菌剤がPorphyromonas gingivalisの形成するバイオフィルムに及ぼす影響2009

    • Author(s)
      前薗葉月, 野杁由一郎, 朝日陽子, 山口幹代, 山本れいこ, 薮根敏晃, 上田未央, 恵比須繁之
    • Journal Title

      Bacterial Adherence & Biofilm 23(in press)

    • Data Source
      KAKENHI-PROJECT-19592198
  • [Journal Article] 特集・口腔管理と全身疾患 歯科と医科の連携~12009

    • Author(s)
      恵比須繁之、山口幹代
    • Journal Title

      口腔内のメーン感染源医薬ジャーナル 45

      Pages: 2749-2754

    • Data Source
      KAKENHI-PROJECT-21890133
  • [Journal Article] 各種のPorphyromonas gingivalis菌株が形成するバイオフィルムに対すAzithromycinの影響2007

    • Author(s)
      野杁由一郎, 野口展生, 朝日陽子, 山口幹代, 恵比須繁之
    • Journal Title

      Bacterial Adherence & Biofilms 20

      Pages: 104-109

    • Data Source
      KAKENHI-PROJECT-19592198
  • [Presentation] Porphyromonas gignivalis のバイオフィルム形成におけるプロテアーゼの役割.2012

    • Author(s)
      山口幹代
    • Organizer
      第136回日本歯科保存学会
    • Place of Presentation
      沖縄コンベンションセンター(沖縄)
    • Year and Date
      2012-06-28
    • Data Source
      KAKENHI-PROJECT-23792171
  • [Presentation] Remnant matrix of Porphyromonas gingivalis biofilms treated with chlorhexidine2011

    • Author(s)
      Yamaguchi Mikiyo
    • Organizer
      International Union of Microbiological Societies 2011 Congress
    • Place of Presentation
      札幌コンベンションセンター(札幌)
    • Year and Date
      2011-09-09
    • Data Source
      KAKENHI-PROJECT-23792171
  • [Presentation] Porphyromonas gingivalis のバイオフィルムに対するクロルヘキシジンの影響2011

    • Author(s)
      山口幹代
    • Organizer
      第25回 Bacterial Adherence & Biofilm 学術集会
    • Place of Presentation
      東京慈恵会医科大学 (東京)
    • Year and Date
      2011-07-08
    • Data Source
      KAKENHI-PROJECT-23792171
  • [Presentation] Porphyromonas ginigvalisのバイオフィルムに対するクロルヘキシジンの影響2011

    • Author(s)
      山口幹代、野杁由一郎、久保庭雅恵、山本れいこ、前薗葉月、朝日陽子、呉本勝隆、恵比須繁之
    • Organizer
      第25回Bacterial Adherence & Biofilm学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23792171
  • [Presentation] バイオフィルムにおける菌体外マトリックス産生と抗菌剤の影響2010

    • Author(s)
      山口幹代, ら
    • Organizer
      第132回日本歯科保存学会春季学術大会
    • Place of Presentation
      崇城大学市民ホール(熊本県)
    • Year and Date
      2010-06-04
    • Data Source
      KAKENHI-PROJECT-21890133
  • [Presentation] Exopolysaccharide accumulation and antimicrobial effect in Porphyromonas gingivalis biofilm2010

    • Author(s)
      YAMAGUCHI MIKIYO, et al.
    • Organizer
      IADR 88^<th> General Session and Exhibition
    • Place of Presentation
      Centre Convencions Internacional Barcelona(スパイン)
    • Year and Date
      2010-07-15
    • Data Source
      KAKENHI-PROJECT-21890133
  • [Presentation] Exopolysaccharide accumulation and antimicrobial effect in Porphyromonas gingivalis biofilm.2010

    • Author(s)
      山口幹代
    • Organizer
      IADR 88^<th> General Session and Exhibition
    • Place of Presentation
      バルセロナ
    • Year and Date
      2010-07-15
    • Data Source
      KAKENHI-PROJECT-21890133
  • [Presentation] Porphyromonas gingivalisバイオフィルムの菌体外マトリックスに対する陽イオン性抗菌剤の影響2010

    • Author(s)
      山口幹代, ら
    • Organizer
      第133回日本歯科保存学会秋季学術大会
    • Place of Presentation
      長良川国際会議場(岐阜県)
    • Year and Date
      2010-10-28
    • Data Source
      KAKENHI-PROJECT-21890133
  • [Presentation] Porphyromonas gingivalisバイオフィルムの菌体外マトリックスに対する陽イオン性抗菌剤の影響2010

    • Author(s)
      山口幹代
    • Organizer
      第133回日本歯科保存学会
    • Place of Presentation
      長良川国際会議場(岐阜)
    • Year and Date
      2010-10-28
    • Data Source
      KAKENHI-PROJECT-21890133
  • [Presentation] Porphyromonas gingivalisバイオフィルムにおける菌体外マトリックス産生と抗菌剤の影響2010

    • Author(s)
      山口幹代
    • Organizer
      第132回日本歯科保存学会
    • Place of Presentation
      熊本市国際交流会館(熊本)
    • Year and Date
      2010-06-04
    • Data Source
      KAKENHI-PROJECT-21890133
  • [Presentation] Investigation on factors causing refractory periapical periodontitis in general practices

    • Author(s)
      Mikiyo Yamaguchi, Yuichiro Noiri, Yoshihiro Ito, Shungo Komichi, Mikako Hayashi
    • Organizer
      第9回世界歯内療法会議
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25861798
  • [Presentation] Porphyromonas gingivalisのバイオフィルムの形成におけるプロテアーゼの役割

    • Author(s)
      山口幹代
    • Organizer
      日本歯科保存学会春季学術大会
    • Place of Presentation
      沖縄
    • Data Source
      KAKENHI-PROJECT-23792171
  • [Presentation] Dispersal of Porphyromonas gingivalis biofilm induced by environmental factors and proteases

    • Author(s)
      Mikiyo Yamaguchi
    • Organizer
      6th ASM Conference on Biofilms 2012
    • Place of Presentation
      マイアミ
    • Data Source
      KAKENHI-PROJECT-23792171
  • 1.  EBISU Shigeyuki (50116000)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 3 results
  • 2.  NOIRI Yuichiro (50218286)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 3.  ASAHI Yoko (50456943)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 4.  前薗 葉月 (00613390)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 5.  UEDA Mio (90423136)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  YOSHITAKE Fumio (10452450)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  KINOMOTO Yoshifumi (10252694)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  TAKAHASHI Yusuke (60397693)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  NAKANO Takayoshi (30243182)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  米田 直道 (80781640)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  大墨 竜也 (30759725)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  竹中 彰治 (50313549)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  湯本 浩通 (60284303)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  呉本 勝隆 (40734306)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  山本 れいこ (70636133)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  久保庭 雅恵 (00303983)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  岡本 菜々子 (60781432)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  大嶋 淳 (30755450)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  MATSUI Saori
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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