YAMAGUCHI MIKIYO 山口幹代

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YAMAGUCHI Mikiyo 山口幹代

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Researcher Number	30523089
Other IDs
Affiliation (Current)	2023: 大阪大学, 大学院歯学研究科, 招へい教員
Affiliation (based on the past Project Information) *help	2021 – 2022: 大阪大学, 歯学研究科, 招へい教員 2020: 大阪大学, 歯学研究科, 特任研究員 2017 – 2018: 大阪大学, 歯学研究科, 特任研究員 2016 – 2017: 大阪大学, 歯学研究科, 助教 2015: 大阪大学, 歯学研究科(研究院), 助教 2014: 大阪大学, 歯学部付属病院, 医員 2009 – 2014: Osaka University, 歯学部附属病院, 医員
Review Section/Research Field	Principal Investigator Conservative dentistry / Basic Section 57030:Conservative dentistry-related Except Principal Investigator Conservative dentistry / Basic Section 57030:Conservative dentistry-related
Keywords	Principal Investigator バイオフィルム / バイオフィルムの能動的脱離 / 歯性菌血症 / デンタルバイオフィルム / 根尖性歯周炎 / シーケンス解析 / 口腔内細菌叢 / 難治性根尖性歯周炎 / ポリフィロモナス　ジンジバリス / 抗菌薬感受性 … More / ポルフィロモナス　ジンジバリス / 薬剤排出ポンプ / 抗菌薬抵抗性 / ポルフィロモナスジンジバリス / クロルヘキシジン / 共焦点レーザー顕微鏡 / ホリフィロモナスジンジバリス / 透過型電子顕微鏡 / 走査型電子顕微鏡 / 塩化セチルピリジニウム / グルコン酸クロルヘキシジン / Porphyromonas gingivalis / 菌体外マトリックス / ポルフィロモナスジンジバリス / 抗菌剤 / 歯学 … More Except Principal Investigator バイオフィルム / 細菌 / 歯学 / 免疫学 / 微生物学 / 口腔細菌学 / ﾘｱﾙﾀｲﾑPCR / 病理組織学的観察 / EMAT / 電磁波照射 / 感染根管治療 / リアルタイムPCR / マイクロCT / 創傷の治癒 / 高周波根尖療法 / 電磁波 / 免疫組織化学 / ラット / マイクロエンドモデル / Fish法 / Ｆｉｓｈ法 / ハイドロキシアパタイト / 抗バイオフィルム薬 / 16S rRNA遺伝子解析 / 共焦点レーザー顕微鏡 / ハイドロキイアパタイト / メタゲノム解析 / in situ / デンタルバイオフィルム / オートインデューサー / Sub-MIC / アジスロマイシン / クオラムセンシング / 抗菌薬 / 難治性根尖性歯周炎 / Porphyromonas gingivalis / 抗生物質 / マクロライド / 歯周炎 / 歯内療法学 Less

Comprehensive analysis of host signaling infected by periodontopathogenic bacteria.
- Principal Investigator
  
  大嶋淳
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Osaka University
歯性菌血症の克服を目指したデンタルバイオフィルムの能動的脱離メカニズムの解明Principal Investigator
- Principal Investigator
  
  山口幹代
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Osaka University
Association of the onset of refractory periapical periodontitis with oral microbiotaPrincipal Investigator
- Principal Investigator
  
  Yamaguchi Mikiyo
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  Osaka University
Establishment of micro-endodontic model in small animal and development of root canal treatment tschnique and root canal treatment drugs
- Principal Investigator
  
  NOIRI Yuichiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Conservative dentistry
- Research Institution
  Niigata University
  Osaka University
Role of multidrug efflux pumps on Porphyromonas gingivalis biofilmPrincipal Investigator
- Principal Investigator
  
  Yamaguchi Mikiyo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Conservative dentistry
- Research Institution
  Osaka University
Comprehensive in situ analysis of dental biofilm formation and control
- Principal Investigator
  
  EBISU Shigeyuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Conservative dentistry
- Research Institution
  Osaka University
Analysis of residual Porphyromonas gingivalis biofilms in vitroaftertreatment with antibioticPrincipal Investigator
- Principal Investigator
  
  YAMAGUCHI Mikiyo
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Conservative dentistry
- Research Institution
  Osaka University
A study on antibiotic resistance of Porphyromonas gingivalis biofilmPrincipal Investigator
- Principal Investigator
  
  YAMAGUCHI Mikiyo
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Conservative dentistry
- Research Institution
  Osaka University
Effects of macrolides on Porphyromonas gingivalis biofolms
- Principal Investigator
  
  UEDA Mio
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  Osaka University

All 2018 2017 2015 2014 2013 2012 2011 2010 2009 2007 Other

All Journal Article Presentation Book

[Book] 根尖病変治癒へ向けた戦略を究める2013
- Author(s)
  山口幹代、野杁由一郎、
- Total Pages
  12
- Publisher
  ヒョーロン・パブリッシャーズ
- Data Source
  KAKENHI-PROJECT-25861798
[Book] 根尖病変治癒に向けた戦略を究める2013
- Author(s)
  山口幹代, 野杁由一郎
- Publisher
  ヒョーロン・パブリッシャーズ
- Data Source
  KAKENHI-PROJECT-23792171
[Book] 高齢者の肺炎～治療・リハビリテーション・予防～II(1.高齢者の肺炎原因微生物と口腔内衛生状況1)口腔内細菌と誤嚥性肺炎)2011
- Author(s)
  山口幹代, ら
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-21890133
[Book] 高齢者の肺炎～治療・リハビリテーション・予防～II2011
- Author(s)
  山口幹代、恵比須繁之
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-21890133
[Journal Article] Factors that cause endodontic failures in general practices in Japan2018
- Author(s)
  Mikiyo Yamaguchi, Yuichiro Noiri, Yoshihiro Itoh, Sungo Komichi, Kyoko Yagi, Reo Uemura, Haruna Naruse, Saori Matsui, Nanako Kuriki, Mikako Hayashi and Shigeyuki Ebisu
- Journal Title
  
  BMC Oral Health
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11548
[Journal Article] Factors that cause endodontic failures in general practices in Japan.2018
- Author(s)
  Yamaguchi M, Noiri Y, Itoh Y, Komichi S, Yagi K, Uemura R, Naruse H, Matsui S, Kuriki N, Hayashi M, Ebisu S
- Journal Title
  
  BMC Oral Health.
  
  Volume: 18(1) Issue: 1 Pages: 70-70
- DOI
  10.1186/s12903-018-0530-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K17062, KAKENHI-PROJECT-17H04384, KAKENHI-PROJECT-16K11548
[Journal Article] Investigation on Effective Education Methods for Preparing Curved Root Canals with FKG RaCe2017
- Author(s)
  山口幹代, 伊藤勇紀, 須崎尚子, 堅田千裕, 外園真規, 川西雄三, 増田晃一, 伊藤善博, 米田直道, 岡本基岐, 朝日陽子, 山田朋美, 伊藤祥作, 林美加子
- Journal Title
  
  The Japanese Journal of Conservative Dentistry
  
  Volume: 60 Issue: 5 Pages: 255-261
- DOI
  10.11471/shikahozon.60.255
- NAID
  130006191148
- ISSN
  0387-2343, 2188-0808
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11548
[Journal Article] Inhibition of polysaccharide synthesis by the sinR orthologue PGN_0088 is indirectly associated with the penetration of Porphyromonas gingivalis biofilms by macrolide antibiotics.2015
- Author(s)
  Yamamoto R, Noiri Y, Yamaguchi M, Asahi Y, Maezono H, Ebisu S, Hayashi M
- Journal Title
  
  Microbiology
  
  Volume: 161 Issue: 2 Pages: 422-429
- DOI
  10.1099/mic.0.000013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25861798, KAKENHI-PROJECT-26462878, KAKENHI-PROJECT-26861593
[Journal Article] Effects of the tea catechin epigallocatechin gallate on Porphyromonas gingivalis biofilms2014
- Author(s)
  Asahi Y. et al.
- Journal Title
  
  Jouranl of Applied Microbiology
  
  Volume: 116 Issue: 5 Pages: 1164-1171
- DOI
  10.1111/jam.12458
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390424, KAKENHI-PROJECT-24390425, KAKENHI-PROJECT-24792020, KAKENHI-PROJECT-25450103, KAKENHI-PROJECT-25462957, KAKENHI-PROJECT-25861796, KAKENHI-PROJECT-25861798, KAKENHI-PROJECT-26462878
[Journal Article] Porphyromonas gingivalis biofilms persist after chlorhexidine treatment2013
- Author(s)
  Mikiyo Yamaguchi, Yuichiro Noiri, Masae Kuboniwa, Reiko Yamamoto, Yoko Asahi, Hazuki Maezono, Mikako Hayashi, Shigeyuki Ebisu
- Journal Title
  
  European Journal of Oral Sciences.
  
  Volume: 121 Pages: 162-168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23792171
[Journal Article] Porphyromonas gingivalis biofilms persist after chlorhexidine treatment2013
- Author(s)
  Yamaguchi M, Noiri Y, Kuboniwa M, Yamamoto R, Asahi Y, Maezono H, Hayashi M, Ebisu S
- Journal Title
  
  Eur J Oral Sci
  
  Volume: Vol.121 Issue: 3pt1 Pages: 162-8
- DOI
  10.1111/eos.12050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890103, KAKENHI-PROJECT-24390425, KAKENHI-PROJECT-24593150, KAKENHI-PROJECT-24792020, KAKENHI-PROJECT-25293387, KAKENHI-PROJECT-25861796
[Journal Article] Porphyromonas gingivalis biofilms persist after chlorhexidine treatment2013
- Author(s)
  Mikiyo Yamaguchi
- Journal Title
  
  European Journal of Oral Sciences
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23792171
[Journal Article] 根尖孔外バイオフィルムと根尖性歯周炎の難治化2012
- Author(s)
  山口幹代, 野杁由一郎
- Journal Title
  
  日本歯科評論
  
  Volume: 72 Pages: 41-50
- Data Source
  KAKENHI-PROJECT-23792171
[Journal Article] 根管治療を再考するーその成功と失敗の鍵ー2011
- Author(s)
  野杁由一郎, 山口幹代, 林美加子, 恵比須繁之
- Journal Title
  
  日歯内療誌
  
  Volume: 32 Pages: 87-96
- NAID
  10029089649
- Data Source
  KAKENHI-PROJECT-23792171
[Journal Article] Porphyromonas gingivalisのバイオフィルムに対するクロルヘキシジンの影響2011
- Author(s)
  山口幹代, 野杁由一郎, 久保庭雅恵, 山本れいこ, 前薗葉月, 朝日陽子, 呉本勝隆 , 恵比須繁之
- Journal Title
  
  Bacterial Adherence & Biofilm
  
  Volume: 25 Pages: 53-58
- Data Source
  KAKENHI-PROJECT-23792171
[Journal Article] Porphyromonas ginigvalisのバイオフィルムに対するクロルヘキシジンの影響2011
- Author(s)
  山口幹代、野杁由一郎、久保庭雅恵、山本れいこ、前薗葉月、朝日陽子、呉本勝隆、恵比須繁之
- Journal Title
  
  Bacterial Adherence & Biofilm
  
  Volume: Vol.25 Pages: 53-58
- Data Source
  KAKENHI-PROJECT-23792171
[Journal Article] A Porphyromo nas gingivais mutant defective in a putative glycosyltransferase exhibits defective biosynthesis of the polysac charide portions of lipopolysacharide, decreased gingipain activities, strong autoaggregation, and increased biofilm formation.2010
- Author(s)
  Mikiyo Yamaguchi, Keiko Sato, Hideharu Yukitake, Yuichiro Noiri, Shigeyuki Ebisu, Koji Nakayama
- Journal Title
  
  Infection and Immunity. 78
  
  Pages: 3801-3812
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890133
[Journal Article] A Porphyromonas gingivalis mutant defective in a putative glycosyltransferase exhibits defective biosynthesis of the polysaccharide portions of lipopolysaccharide, decreased gingipain activities strong autoaggregation, and increased biofilm formation2010
- Author(s)
  YAMAGUCHI MIKIYO, et al.
- Journal Title
  
  Infection and Immunity
  
  Volume: VOL78 Pages: 3801-3812
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890133
[Journal Article] 口腔内のメーン感染源～オーラルバイオフィルム～2009
- Author(s)
  山口幹代
- Journal Title
  
  医薬ジャーナル Vol.45
  
  Pages: 71-76
- Data Source
  KAKENHI-PROJECT-21890133
[Journal Article] 各種抗菌剤がPorphyromonas gingivalisの形成するバイオフィルムに及ぼす影響2009
- Author(s)
  前薗葉月, 野杁由一郎, 朝日陽子, 山口幹代, 山本れいこ, 薮根敏晃, 上田未央, 恵比須繁之
- Journal Title
  
  Bacterial Adherence & Biofilm 23(in press)
- Data Source
  KAKENHI-PROJECT-19592198
[Journal Article] 特集・口腔管理と全身疾患歯科と医科の連携～12009
- Author(s)
  恵比須繁之、山口幹代
- Journal Title
  
  口腔内のメーン感染源医薬ジャーナル 45
  
  Pages: 2749-2754
- Data Source
  KAKENHI-PROJECT-21890133
[Journal Article] 各種のPorphyromonas gingivalis菌株が形成するバイオフィルムに対すAzithromycinの影響2007
- Author(s)
  野杁由一郎, 野口展生, 朝日陽子, 山口幹代, 恵比須繁之
- Journal Title
  
  Bacterial Adherence & Biofilms 20
  
  Pages: 104-109
- Data Source
  KAKENHI-PROJECT-19592198
[Presentation] Porphyromonas gignivalis のバイオフィルム形成におけるプロテアーゼの役割.2012
- Author(s)
  山口幹代
- Organizer
  第136回日本歯科保存学会
- Place of Presentation
  沖縄コンベンションセンター(沖縄)
- Year and Date
  2012-06-28
- Data Source
  KAKENHI-PROJECT-23792171
[Presentation] Remnant matrix of Porphyromonas gingivalis biofilms treated with chlorhexidine2011
- Author(s)
  Yamaguchi Mikiyo
- Organizer
  International Union of Microbiological Societies 2011 Congress
- Place of Presentation
  札幌コンベンションセンター(札幌)
- Year and Date
  2011-09-09
- Data Source
  KAKENHI-PROJECT-23792171
[Presentation] Porphyromonas gingivalis のバイオフィルムに対するクロルヘキシジンの影響2011
- Author(s)
  山口幹代
- Organizer
  第25回 Bacterial Adherence & Biofilm 学術集会
- Place of Presentation
  東京慈恵会医科大学 (東京)
- Year and Date
  2011-07-08
- Data Source
  KAKENHI-PROJECT-23792171
[Presentation] Porphyromonas ginigvalisのバイオフィルムに対するクロルヘキシジンの影響2011
- Author(s)
  山口幹代、野杁由一郎、久保庭雅恵、山本れいこ、前薗葉月、朝日陽子、呉本勝隆、恵比須繁之
- Organizer
  第25回Bacterial Adherence & Biofilm学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23792171
[Presentation] バイオフィルムにおける菌体外マトリックス産生と抗菌剤の影響2010
- Author(s)
  山口幹代, ら
- Organizer
  第132回日本歯科保存学会春季学術大会
- Place of Presentation
  崇城大学市民ホール(熊本県)
- Year and Date
  2010-06-04
- Data Source
  KAKENHI-PROJECT-21890133
[Presentation] Exopolysaccharide accumulation and antimicrobial effect in Porphyromonas gingivalis biofilm2010
- Author(s)
  YAMAGUCHI MIKIYO, et al.
- Organizer
  IADR 88^<th> General Session and Exhibition
- Place of Presentation
  Centre Convencions Internacional Barcelona(スパイン)
- Year and Date
  2010-07-15
- Data Source
  KAKENHI-PROJECT-21890133
[Presentation] Exopolysaccharide accumulation and antimicrobial effect in Porphyromonas gingivalis biofilm.2010
- Author(s)
  山口幹代
- Organizer
  IADR 88^<th> General Session and Exhibition
- Place of Presentation
  バルセロナ
- Year and Date
  2010-07-15
- Data Source
  KAKENHI-PROJECT-21890133
[Presentation] Porphyromonas gingivalisバイオフィルムの菌体外マトリックスに対する陽イオン性抗菌剤の影響2010
- Author(s)
  山口幹代, ら
- Organizer
  第133回日本歯科保存学会秋季学術大会
- Place of Presentation
  長良川国際会議場(岐阜県)
- Year and Date
  2010-10-28
- Data Source
  KAKENHI-PROJECT-21890133
[Presentation] Porphyromonas gingivalisバイオフィルムの菌体外マトリックスに対する陽イオン性抗菌剤の影響2010
- Author(s)
  山口幹代
- Organizer
  第133回日本歯科保存学会
- Place of Presentation
  長良川国際会議場(岐阜)
- Year and Date
  2010-10-28
- Data Source
  KAKENHI-PROJECT-21890133
[Presentation] Porphyromonas gingivalisバイオフィルムにおける菌体外マトリックス産生と抗菌剤の影響2010
- Author(s)
  山口幹代
- Organizer
  第132回日本歯科保存学会
- Place of Presentation
  熊本市国際交流会館(熊本)
- Year and Date
  2010-06-04
- Data Source
  KAKENHI-PROJECT-21890133
[Presentation] Investigation on factors causing refractory periapical periodontitis in general practices
- Author(s)
  Mikiyo Yamaguchi, Yuichiro Noiri, Yoshihiro Ito, Shungo Komichi, Mikako Hayashi
- Organizer
  第9回世界歯内療法会議
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25861798
[Presentation] Porphyromonas gingivalisのバイオフィルムの形成におけるプロテアーゼの役割
- Author(s)
  山口幹代
- Organizer
  日本歯科保存学会春季学術大会
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-23792171
[Presentation] Dispersal of Porphyromonas gingivalis biofilm induced by environmental factors and proteases
- Author(s)
  Mikiyo Yamaguchi
- Organizer
  6th ASM Conference on Biofilms 2012
- Place of Presentation
  マイアミ
- Data Source
  KAKENHI-PROJECT-23792171

1. EBISU Shigeyuki (50116000)

# of Collaborated Projects: 5 results

# of Collaborated Products: 3 results
2. NOIRI Yuichiro (50218286)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. ASAHI Yoko (50456943)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. 前薗葉月 (00613390)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. UEDA Mio (90423136)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. YOSHITAKE Fumio (10452450)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KINOMOTO Yoshifumi (10252694)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TAKAHASHI Yusuke (60397693)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. NAKANO Takayoshi (30243182)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 米田直道 (80781640)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 大墨竜也 (30759725)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 竹中彰治 (50313549)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 湯本浩通 (60284303)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 呉本勝隆 (40734306)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 山本れいこ (70636133)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 久保庭雅恵 (00303983)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 岡本菜々子 (60781432)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 大嶋淳 (30755450)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. MATSUI Saori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YAMAGUCHI MIKIYO 山口 幹代

YAMAGUCHI Mikiyo 山口 幹代

Research Projects

Research Products

Co-Researchers

Comprehensive analysis of host signaling infected by periodontopathogenic bacteria.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

歯性菌血症の克服を目指したデンタルバイオフィルムの能動的脱離メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

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Association of the onset of refractory periapical periodontitis with oral microbiotaPrincipal Investigator

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Establishment of micro-endodontic model in small animal and development of root canal treatment tschnique and root canal treatment drugs

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Role of multidrug efflux pumps on Porphyromonas gingivalis biofilmPrincipal Investigator

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Comprehensive in situ analysis of dental biofilm formation and control

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Analysis of residual Porphyromonas gingivalis biofilms in vitroaftertreatment with antibioticPrincipal Investigator

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A study on antibiotic resistance of Porphyromonas gingivalis biofilmPrincipal Investigator

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Effects of macrolides on Porphyromonas gingivalis biofolms

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[Book] 根尖病変 治癒へ向けた戦略を究める2013

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[Book] 根尖病変 治癒に向けた戦略を究める2013

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[Book] 高齢者の肺炎～治療・リハビリテーション・予防～II(1.高齢者の肺炎原因微生物と口腔内衛生状況1)口腔内細菌と誤嚥性肺炎)2011

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[Book] 高齢者の肺炎～治療・リハビリテーション・予防～II2011

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[Journal Article] Factors that cause endodontic failures in general practices in Japan2018

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YAMAGUCHI MIKIYO 山口幹代

YAMAGUCHI Mikiyo 山口幹代

[Book] 根尖病変治癒へ向けた戦略を究める2013

[Book] 根尖病変治癒に向けた戦略を究める2013

[Journal Article] 特集・口腔管理と全身疾患歯科と医科の連携～12009