NAKANO Daisuke 中野大介

Researcher Number	30524178
Other IDs	https://orcid.org/0000-0002-7435-8465
Affiliation (based on the past Project Information) *help	2022: 香川大学, 医学部, 准教授 2018 – 2020: 香川大学, 医学部, 准教授 2011 – 2017: 香川大学, 医学部, 助教
Review Section/Research Field	Principal Investigator General pharmacology / Basic Section 48030:Pharmacology-related
Keywords	Principal Investigator 急性腎障害 / 尿細管 / 近位尿細管 / 敗血症 / p21 / 腎臓 / バリアー / 敗血症性急性腎障害 / リプログラミング / 糖取り込み … More / 糖尿病 / GLUT2 / SGLT2 / 微小環境変化 / 乏尿 / 生体イメージング / Acute kidney injury / 再生 / プレコンディショニング / 細胞周期 / レニン・アンジオテンシン系 / 細胞老化 / 糖尿病性腎症 Less

尿細管バリアシステム破壊機序の加齢性変化解明と、それに対抗するための創薬研究Principal Investigator
- Principal Investigator
  
  中野大介
- Project Period (FY)
  2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Kagawa University
regulating glucose uptake in renal proximal tubules for treating chronic cardiorenal failure.Principal Investigator
- Principal Investigator
  
  Nakano Daisuke
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Kagawa University
exploring the mechanism of septic acute kidney injury(Fostering Joint International Research)Principal Investigator
- Principal Investigator
  
  Nakano Daisuke
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Research Field
  
  General pharmacology
- Research Institution
  Kagawa University
exploring the mechanism of septic acute kidney injuryPrincipal Investigator
- Principal Investigator
  
  Nakano Daisuke
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kagawa University
role of p21 activation and senescence on acute kidney injuryPrincipal Investigator
- Principal Investigator
  
  NAKANO Daisuke
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kagawa University
the role of renal tubular p21 in diabetic nephropathyPrincipal Investigator
- Principal Investigator
  
  NAKANO Daisuke
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kagawa University

All 2021 2019 2018 2017 2014 2013 2012 2011

All Journal Article Presentation

[Journal Article] Diuretic Effects of Sodium Glucose Cotransporter 2 Inhibitors and Their Influence on the Renin-Angiotensin System2019
- Author(s)
  Ansary Tuba M.、Nakano Daisuke、Nishiyama Akira
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 3 Pages: 629-629
- DOI
  10.3390/ijms20030629
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06893, KAKENHI-PROJECT-18H03191
[Journal Article] Guanylyl cyclase A in both renal proximal tubular and vascular endothelial cells protects the kidney against acute injury in rodent experimental endotoxemia models.2018
- Author(s)
  Kitamura K, Nakano D, Sawanobori Y, Asaga T, Yokoi H, Yanagita M, Mukoyama M, Yokudome T, Kangawa K, shirakami G, Nishiyama A.
- Journal Title
  
  Anesthesiology
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08236
[Journal Article] Guanylyl cyclase A in both renal proximal tubular and vascular endothelial cells protects the kidney against acute injury in rodent experimental endotoxemia models.2018
- Author(s)
  Kidney against Acute Injury in Rodent Experimental Endotoxemia Models. Kitamura H, Nakano D, Sawanobori Y, Asaga T, Yokoi H, Yanagita M, Mukoyama M, Tokudome T, Kangawa K, Shirakami G, Nishiyama A.
- Journal Title
  
  Anesthesiology
  
  Volume: 印刷中 Issue: 2 Pages: 296-310
- DOI
  10.1097/aln.0000000000002214
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KK0346, KAKENHI-PROJECT-17K09697, KAKENHI-PROJECT-17K09706, KAKENHI-PROJECT-17K09897, KAKENHI-PUBLICLY-18H04673, KAKENHI-PROJECT-18H03191, KAKENHI-PROJECT-17K19677
[Journal Article] p21 is essential for the beneficial effects of renal ischemic preconditioning on renal ischemia-reperfusion injury in mice.2014
- Author(s)
  Nishioka S, Nakano D, Kitada K, Sofue T, Ohsaki H, Moriwaki K, Hara T, Ohmori K, Kohno M, Nishiyama A.
- Journal Title
  
  Kidney International
  
  Volume: 85 Issue: 4 Pages: 871-879
- DOI
  10.1038/ki.2013.496
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791653, KAKENHI-PROJECT-25860190
[Presentation] In vivo analysis of glucose uptake in proximal tubules under SGLT2 inhibitor treatment2021
- Author(s)
  中野大介. Anqi Zhang. 西山成
- Organizer
  第24回日本心血管内分泌代謝学会学術総会/24h CVEM
- Data Source
  KAKENHI-PROJECT-18K06893
[Presentation] 生体における近位尿細管糖取り込みキネティクスとSGLT2阻害薬による影響2021
- Author(s)
  Anqi Zhang, 中野大介、西山成
- Organizer
  第64回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-18K06893
[Presentation] Renal capillary flow and hypoxia in kidney injury2018
- Author(s)
  Daisuke Nakano
- Organizer
  ISN Frontiers meeting, Kidney disease & cardiovascular disease
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08236
[Presentation] Renal capillary flow and hypoxia in kidney injury2018
- Author(s)
  Daisuke Nakano
- Organizer
  ISN Frontiers meeting, Kidney disease & cardiovascular disease 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KK0346
[Presentation] ANPによる急性腎障害改善作用の機序2017
- Author(s)
  北村裕亮、中野大介、西山成
- Organizer
  第46回日本心脈管作動物質学会
- Data Source
  KAKENHI-PROJECT-15K08236
[Presentation] LPS 誘導性急性腎障害において ANP は血管内皮細胞および近位尿細管細胞に作用し改善効果を示す2017
- Author(s)
  北村裕亮、中野大介、澤登慶治、西山成
- Organizer
  第27回日本循環薬理学会
- Data Source
  KAKENHI-PROJECT-15K08236
[Presentation] LPS 誘導性急性腎障害において ANP は血管内皮細胞および近位尿細管細胞に作用し改善効果を示す2017
- Author(s)
  北村裕亮、中野大介、澤登慶治、西山成
- Organizer
  第27回日本循環薬理学会
- Data Source
  KAKENHI-PROJECT-15KK0346
[Presentation] In vivoリアルタイムイメージングによる細胞内生命現象と腎機能との関係解析2014
- Author(s)
  中野大介
- Organizer
  第14回日本NO学会学術集会
- Place of Presentation
  佐賀
- Invited
- Data Source
  KAKENHI-PROJECT-25860190
[Presentation] 2型糖尿病ラット OLETF の腎において蓄積した老化細胞はテルミサルタン投与により除かれるが、テンポールでは効果はみられない2013
- Author(s)
  中野大介、北田研人、大崎博之、人見浩史、小堀浩幸、今西政仁、西山成
- Organizer
  日本薬理学会第86回年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23790299
[Presentation] 2型糖尿病ラットOLETFの腎において蓄積した老化細胞はテルミサルタン投与により除かれるが、テンポールでは効果はみられない2013
- Author(s)
  中野大介
- Organizer
  日本薬理学会第86回年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23790299
[Presentation] 2 型糖尿病ラット OLETFの腎において蓄積した老化細胞はテルミサルタン投与により除かれる2012
- Author(s)
  中野大介、北田研人、人見浩史、小堀浩幸、西山成
- Organizer
  第55回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790299
[Presentation] cyclin-dependent kinase inhibitor p21 は糖尿病腎にみられる近位尿細管細胞の老化を惹起する2012
- Author(s)
  北田研人, 中野大介, 人見浩史, 小堀浩幸、西山成
- Organizer
  日本薬理学会第85回年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23790299
[Presentation] Telmisartan but not tempol improves the already established renal cell senescence in type 2 diabetic rats.2012
- Author(s)
  中野大介
- Organizer
  66h Council for high blood pressure research
- Place of Presentation
  Washington D.C., USA
- Data Source
  KAKENHI-PROJECT-23790299
[Presentation] Telmisartan but not tempol improves the already established renal cell senescence in type 2 diabetic rats2012
- Author(s)
  Nakano D, Kitada K, Ohsaki H, Hitomi H, Kobori H, Imanishi M, Nishiyama A
- Organizer
  66^hCouncil for high blood pressure research
- Place of Presentation
  Washington D.C., USA
- Data Source
  KAKENHI-PROJECT-23790299
[Presentation] 2型糖尿病ラットOLETFの腎において蓄積した老化細胞はテルミサルタン投与により除かれる2012
- Author(s)
  中野大介
- Organizer
  第55回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790299
[Presentation] High glucose-induced increase in p21 causes cellular senescence in proximal tubules of diabetic nephropathy2011
- Author(s)
  Kitada K, Nakano D, Hitomi H, Kobori H, Nishiyama A
- Organizer
  65^<th>Council for high blood pressure research
- Place of Presentation
  Orlando, FL, USA
- Data Source
  KAKENHI-PROJECT-23790299
[Presentation] 糖尿病腎における細胞老化はインスリンにより改善する2011
- Author(s)
  北田研人, 中野大介, 人見浩史, 西山成
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790299

1. Titze Jens

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. Wiig Helge

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. SOFUE Tadashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NAKANO Daisuke 中野 大介

Research Projects

Research Products

Co-Researchers

尿細管バリアシステム破壊機序の加齢性変化解明と、それに対抗するための創薬研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

regulating glucose uptake in renal proximal tubules for treating chronic cardiorenal failure.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

exploring the mechanism of septic acute kidney injury(Fostering Joint International Research)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

exploring the mechanism of septic acute kidney injuryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

role of p21 activation and senescence on acute kidney injuryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

the role of renal tubular p21 in diabetic nephropathyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Diuretic Effects of Sodium Glucose Cotransporter 2 Inhibitors and Their Influence on the Renin-Angiotensin System2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Guanylyl cyclase A in both renal proximal tubular and vascular endothelial cells protects the kidney against acute injury in rodent experimental endotoxemia models.2018

Author(s)

Journal Title

Data Source

[Journal Article] Guanylyl cyclase A in both renal proximal tubular and vascular endothelial cells protects the kidney against acute injury in rodent experimental endotoxemia models.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] p21 is essential for the beneficial effects of renal ischemic preconditioning on renal ischemia-reperfusion injury in mice.2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] In vivo analysis of glucose uptake in proximal tubules under SGLT2 inhibitor treatment2021

Author(s)

Organizer

Data Source

[Presentation] 生体における近位尿細管糖取り込みキネティクスとSGLT2阻害薬による影響2021

Author(s)

Organizer

Data Source

[Presentation] Renal capillary flow and hypoxia in kidney injury2018

Author(s)

Organizer

Data Source

[Presentation] Renal capillary flow and hypoxia in kidney injury2018

Author(s)

Organizer

Data Source

[Presentation] ANPによる急性腎障害改善作用の機序2017

Author(s)

Organizer

Data Source

[Presentation] LPS 誘導性急性腎障害において ANP は血管内皮細胞および近位尿細管細胞に作用し改善効果を示す2017

NAKANO Daisuke 中野大介