Arinuma Yoshiyuki 有沼良幸

… Alternative Names

Yoshiyuki Arinuma 有沼良幸

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Researcher Number	30527437
Other IDs	https://orcid.org/0000-0003-1305-991X
Affiliation (Current)	2025: 三重大学, 医学部附属病院, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2023: 北里大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related Except Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related
Keywords	Principal Investigator 神経精神ループス / 全身性エリテマトーデス / MS4A4A / sTREM2 / マイクログリア / アンギオテンシン変換酵素阻害剤 / クローディン５ / 脳血管内皮 / 血液脳関門の破綻 / タイトジャンクション / NPSLE / 自己抗体 / 血液脳関門 … More Except Principal Investigator … More マクロファージ / 破骨細胞 / 単球 / MS4A4A / 関節リウマチ / MS4A4A単球 Less

SLEにおける精神症状発症におけるTREM2を介したマイクログリア活性化機序の解明Principal Investigator
- Principal Investigator
  
  有沼良幸
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Kitasato University
Elucidation of MS4A4A function in rheumatoid arthritis pathogenesis and establishment of basic information for new treatment methods
- Principal Investigator
  
  Yamaoka Kunihiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Kitasato University
Direct Autoantibody-mediated BBB rupture in SLEPrincipal Investigator
- Principal Investigator
  
  Yoshiyuki Arinuma
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Kitasato University

All 2023 2022 2021 2019

All Journal Article Presentation Book

[Book] 関節リウマチ治療実践バイブル改訂第2版2021
- Author(s)
  有沼良幸, 山岡邦宏
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-21K08446
[Journal Article] Real-world efficacy of belimumab in achieving remission or low-disease activity in systemic lupus erythematosus: A retrospective study2023
- Author(s)
  Hasegawa Y., Arinuma Y., Asakura H., Shindo R., Ino K., Kanayama Y., Tanaka T., Matsueda Y., Wada T., Oku K., Yamaoka K.
- Journal Title
  
  Mod Rheumatol.
  
  Volume: - Issue: 4 Pages: 732-740
- DOI
  10.1093/mr/road078
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08446, KAKENHI-PROJECT-20K17449
[Journal Article] Investigation of the poor prognostic factors for life and functional prognosis in patients with asymptomatic dermatomyositis2023
- Author(s)
  Kondo J, Oku K., Hasegwa Y., Muramatsu T., Matsueda Y., Arinuma Y., Yamaoka K.
- Journal Title
  
  Kitasato Med J.
  
  Volume: 53 Pages: 21-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08446
[Journal Article] Varied risk of developing herpes zoster among molecular targeting therapy in rheumatoid arthritis patients: a single-center study.2023
- Author(s)
  Muramatsu T., Oku K., Ikenoue T., Kondo J., Hasegawa Y., Matsueda Y., Arinuma Y., Yamaoka, K
- Journal Title
  
  Kitasato Med J
  
  Volume: 53 Pages: 10-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08446
[Journal Article] The pathogenic role of lupus-specific autoantibodies and Interleukin-6 on demyelination of the brainstem and spinal cord in systemic lupus erythematosus2023
- Author(s)
  Hasegawa Yasuhiro、Arinuma Yoshiyuki、Muramatsu Takumi、Kondou Junichi、Matsueda Yu、Kanayama Yoshiro、Ino Kazuma、Tanaka Tomoki、Wada Tatsuhiko、Oku Kenji、Yamaoka Kunihiro
- Journal Title
  
  Lupus
  
  Volume: 32 Issue: 3 Pages: 401-410
- DOI
  10.1177/09612033231151600
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08792, KAKENHI-PROJECT-21K08446, KAKENHI-PROJECT-20K17449
[Journal Article] Involvement of the complement system in immune thrombocytopenia: review of the literature2023
- Author(s)
  Shindo R., Abe R., Oku K., Tanaka T., Matsueda., Wada T., Arinuma Y., Tanaka S., Ikenoue T., Miyakawa Y., Yamaoka K
- Journal Title
  
  Immunol Med
  
  Volume: 46(4) Issue: 4 Pages: 182-190
- DOI
  10.1080/25785826.2023.2213976
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08446, KAKENHI-PROJECT-20K17449
[Journal Article] Correlation between soluble TREM2 and anti-GluN2 antibody in lupus patients with diffuse psychiatric and neuropsychological syndromes2022
- Author(s)
  Arinuma Yoshiyuki、Hasegawa Yasuhiro、Tanaka Tomoki、Matsueda Yu、Wada Tatsuhiko、Oku Kenji、Yamaoka Kunihiro
- Journal Title
  
  Rheumatology
  
  Volume: 62 Issue: 4 Pages: e105-e106
- DOI
  10.1093/rheumatology/keac488
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08792, KAKENHI-PROJECT-21K08446
[Journal Article] A Case of Anti-MDA5 Antibody-positive Dermatomyositis Developing Reversible Cerebral Vasospasm Syndrome Successfully Treated by Multi-Immunosuppressant Combination Including Mycophenolate Mofetil.2021
- Author(s)
  Muramatsu T, Tono T, Kanayama Y, Hasegawa Y, Kondo J, Hoshiyama T, Wada T, Arinuma Y, Tanaka S, Yamaoka K.
- Journal Title
  
  Modern Rheumatology Case Reports
  
  Volume: 5 (1) Issue: 1 Pages: 69-75
- DOI
  10.1080/24725625.2020.1810398
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08446
[Presentation] 膠原病に伴う慢性血栓塞栓性肺高血圧症の臨床的特徴の検討.2023
- Author(s)
  下手公介、松枝佑、次田奈央、池田慶介、岩楯洋祐、朝倉啓友、田中知樹、和田達彦、有沼良幸、奥健志、田中住明、山岡邦宏.
- Organizer
  第67回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-21K08446
[Presentation] Non-HIV ニューモシスチス肺炎（PCP）に続発した慢性呼吸窮迫症候群（ARDS）対しトシリズマブ（TCZ）が有効であった関節リウマチ（RA）の一例.2023
- Author(s)
  次田奈央、和田達彦、池田慶介、岩楯洋祐、朝倉啓友、下手公介、田中知樹、松枝佑、有沼良幸、奥健志、田中住明、山岡邦宏.
- Organizer
  第67回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-21K08446
[Presentation] べリムマブ投与後に不安症状を呈した全身性エリテマトーデスの1例における髄液IL-6と抗MMDA受容体サブユニットGluN2抗体の変化2023
- Author(s)
  有沼良幸、奥健志、山岡邦宏.
- Organizer
  第51回日本臨床免疫学会総会
- Data Source
  KAKENHI-PROJECT-21K08446
[Presentation] ANCA関連血管炎の寛解維持におけるリツキシマブ治療の効果.2023
- Author(s)
  岩楯洋祐、奥健志、池田慶介、木下奈々、京田俊介、阪本陽介、宍戸瑛理、朝倉啓友、田中知樹、松枝佑、和田達彦、有沼良幸、田中住明、山岡邦宏.
- Organizer
  第67回日本リウマチ学会総会・学術集会.
- Data Source
  KAKENHI-PROJECT-21K08446
[Presentation] 当院における膠原病疾患合併間質性肺疾患（CTD-ILD）に対するnintedanib治療の実際.2023
- Author(s)
  池田慶介、田中知樹、次田奈央、岩楯洋祐、朝倉啓友、下手公介、松枝佑、有沼良幸、和田達彦、奥健志、田中住明、山岡邦宏
- Organizer
  第67回日本リウマチ学会総会・学術集会.
- Data Source
  KAKENHI-PROJECT-21K08446
[Presentation] Effect of Belimumab on Patient-Reported Outcomes in patients with systemic lupus erythematosus.2023
- Author(s)
  Hasegawa Y, Arinuma Y, Oku K, Yamaoka K.
- Organizer
  第67回日本リウマチ学会総会・学術集会.
- Data Source
  KAKENHI-PROJECT-21K08446
[Presentation] JAK阻害第一次無効により他のb/tsDMARDへスイッチを行った関節リウマチ患者尾予後.2023
- Author(s)
  尾方優香、村松匠、有沼良幸、奥健志、山岡邦宏
- Organizer
  第67回日本リウマチ学会総会・学術集会.
- Data Source
  KAKENHI-PROJECT-21K08446
[Presentation] 初発全身性エリテマトーデス患者におけるヒドロキシクロロキン単剤療法の有効性と関連する臨床的因子の検討.2023
- Author(s)
  田中宏昌、長谷川靖浩、有沼良幸、奥健志、山岡邦宏.
- Organizer
  第67回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-21K08446
[Presentation] べリムマブ投与後に不安症状を呈した全身性エリテマトーデスの1例における髄液IL-6と抗NMDA受容体サブユニットGluN2抗体の変化.2023
- Author(s)
  有沼良幸、下出公介、進藤理沙、長谷川靖浩、田中知樹、松枝佑、和田達彦、奥健志、山岡邦宏.
- Organizer
  第67回日本リウマチ学会総会・学術集会.
- Data Source
  KAKENHI-PROJECT-21K08446
[Presentation] Investigation of poor prognostic factors in patients with asymptomatic dermatomyositis2023
- Author(s)
  Kondo J, Oku K, Matseda Y, Hasegawa Y, Muramatsu T, Kanayama Y, Ino K, Shindo R, Arinuma Y, Yamaoka K.
- Organizer
  第67回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-21K08446
[Presentation] Captopril preventing blood brain barrier breach by anti-Smith antibody2023
- Author(s)
  Yoshiyuki Arinuma, Kenji Oku, Kunihiro Yamaoka
- Organizer
  KCR & LUPUS 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08918
[Presentation] Two－Year Outcome of Belimumab Therapy in Patients with Systemic Lupus Erythematosus.2023
- Author(s)
  AsakuraH, Hasegawa Y, Arinuma Y, Tsugita N, Ikeda K, Iwadate Y, Shimode K, Tanaka T, Matsueda Y, Wada T, Tanaka S, Oku K, Yamaoka K.
- Organizer
  第67回日本リウマチ学会総会・学術集会.
- Data Source
  KAKENHI-PROJECT-21K08446
[Presentation] 抗Sm抗体はMMP-2を介してClaudin-5の分解を促進しカプトプリルにより回復する2023
- Author(s)
  有沼良幸、奥健志、山岡邦宏
- Organizer
  第51回日本臨床免疫学会総会
- Data Source
  KAKENHI-PROJECT-21K08446
[Presentation] Anti-Smith Antibody Stimulation to Endothelial Cells Directly Up-regulates MMP-2 Leading to Claudin-5 Degradation2022
- Author(s)
  有沼良幸
- Organizer
  第66回日本リウマチ学会総会・学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08918
[Presentation] 脳血管内皮細胞におけるMMP-2発現上昇とclaudin-5減少に対する抗Sm抗体の直接作用2019
- Author(s)
  有沼良幸
- Organizer
  第63回日本リウマチ学会総会
- Data Source
  KAKENHI-PROJECT-19K08918

1. Yamaoka Kunihiro (20425317)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
2. 松枝佑 (00623208)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
3. 奥健志

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Arinuma Yoshiyuki 有沼 良幸

Yoshiyuki Arinuma 有沼 良幸

Research Projects

Research Products

Co-Researchers

SLEにおける精神症状発症におけるTREM2を介したマイクログリア活性化機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of MS4A4A function in rheumatoid arthritis pathogenesis and establishment of basic information for new treatment methods

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Direct Autoantibody-mediated BBB rupture in SLEPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] 関節リウマチ治療 実践バイブル 改訂第2版2021

Author(s)

Publisher

Data Source

[Journal Article] Real-world efficacy of belimumab in achieving remission or low-disease activity in systemic lupus erythematosus: A retrospective study2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Investigation of the poor prognostic factors for life and functional prognosis in patients with asymptomatic dermatomyositis2023

Author(s)

Journal Title

Data Source

[Journal Article] Varied risk of developing herpes zoster among molecular targeting therapy in rheumatoid arthritis patients: a single-center study.2023

Author(s)

Journal Title

Data Source

[Journal Article] The pathogenic role of lupus-specific autoantibodies and Interleukin-6 on demyelination of the brainstem and spinal cord in systemic lupus erythematosus2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Involvement of the complement system in immune thrombocytopenia: review of the literature2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Correlation between soluble TREM2 and anti-GluN2 antibody in lupus patients with diffuse psychiatric and neuropsychological syndromes2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Case of Anti-MDA5 Antibody-positive Dermatomyositis Developing Reversible Cerebral Vasospasm Syndrome Successfully Treated by Multi-Immunosuppressant Combination Including Mycophenolate Mofetil.2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] 膠原病に伴う慢性血栓塞栓性肺高血圧症の臨床的特徴の検討.2023

Author(s)

Organizer

Data Source

[Presentation] Non-HIV ニューモシスチス肺炎（PCP）に続発した慢性呼吸窮迫症候群（ARDS）対しトシリズマブ（TCZ）が有効であった関節リウマチ（RA）の一例.2023

Author(s)

Organizer

Data Source

[Presentation] べリムマブ投与後に不安症状を呈した全身性エリテマトーデスの1例における髄液IL-6と抗MMDA受容体サブユニットGluN2抗体の変化2023

Author(s)

Organizer

Data Source

[Presentation] ANCA関連血管炎の寛解維持におけるリツキシマブ治療の効果.2023

Author(s)

Organizer

Data Source

[Presentation] 当院における膠原病疾患合併間質性肺疾患（CTD-ILD）に対するnintedanib治療の実際.2023

Author(s)

Organizer

Data Source

Arinuma Yoshiyuki 有沼良幸

Yoshiyuki Arinuma 有沼良幸

[Book] 関節リウマチ治療実践バイブル改訂第2版2021