Ueno Hiroki 上野宏樹

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UENO Hiroki 上野宏樹

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Researcher Number	30529897
Other IDs
Affiliation (Current)	2025: 関西医科大学, 医学部, 研究員 2025: 聖マリアンナ医科大学, 医学部, 講師 2025: 東邦大学, 医学部, 客員講師
Affiliation (based on the past Project Information) *help	2025: 関西医科大学, 医学部, 研究員 2018 – 2023: 聖マリアンナ医科大学, 医学部, 講師 2013 – 2015: 聖マリアンナ医科大学, 医学部, 講師 2011 – 2012: 聖マリアンナ医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Ophthalmology / Basic Section 51030:Pathophysiologic neuroscience-related / Basic Section 56060:Ophthalmology-related
Keywords	Principal Investigator 角膜三叉神経 / マクロファージ / 角膜stem/progenitor細胞 / 角膜幹細胞 / 慢性炎症 / 糖尿病 / 炎症性サイトカイン / 炎症反応 / ニューロトロフィン / TGF-beta … More / TNF-alpha / IL-1beta / TNF-α / IL-1β / 炎症細胞 / 角膜Side population / 角膜stem/progenitor 細胞 / 神経麻痺性角膜炎 / stem/progenitor 細胞 / 角膜 stem/progenitor 細胞 / 三叉神経 / 角膜 Less

角膜三叉神経障害における角膜ミクログリアの役割の解明と治療法開発Principal Investigator
- Principal Investigator
  
  上野宏樹
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Kansai Medical University
Effects of chronic inflammation with diabetes on corneal stem cells and corneal nervesPrincipal Investigator
- Principal Investigator
  
  Ueno Hiroki
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  St. Marianna University School of Medicine
Effect of the corneal stem/progenitor cells during the corneal inflammatory cell infiltrationPrincipal Investigator
- Principal Investigator
  
  Ueno Hiroki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  St. Marianna University School of Medicine
Dependence of corneal stem/progenitor cells on ocular surface innervation.Principal Investigator
- Principal Investigator
  
  UENO Hiroki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  St. Marianna University School of Medicine

All 2022 2020 2016 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Book

[Book] アレルギーの臨床2022
- Author(s)
  村山正承　上野宏樹
- Total Pages
  3
- Publisher
  北隆館
- Data Source
  KAKENHI-PROJECT-18K09463
[Journal Article] Blockade of costimulatory CD27/CD70 pathway promotes corneal allograft survival2020
- Author(s)
  Narimatsu A, Hattori T, Hiroki Ueno et al
- Journal Title
  
  Experimental eye research
  
  Volume: 199 Pages: 108190-108190
- DOI
  10.1016/j.exer.2020.108190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09463, KAKENHI-PROJECT-19K09959, KAKENHI-PROJECT-20H03472, KAKENHI-PROJECT-19K18892
[Journal Article] Interaction between SDF1 and CXCR4 Promotes Photoreceptor Differentiation via Upregulation of NFκB Pathway Signaling Activity in Pax6 Gene-Transfected Photoreceptor Precursors.2020
- Author(s)
  Shimizu J, Suzuki T, Hirotsu C, Ueno H, Takada E, Arimitsu N, Ueda Y, Wakisaka S, Suzuki N.
- Journal Title
  
  Ophthalmic Res.
  
  Volume: 14 Issue: 4 Pages: 1-12
- DOI
  10.1159/000503929
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09463, KAKENHI-PROJECT-17K10009, KAKENHI-PROJECT-17K10852, KAKENHI-PROJECT-17K11494, KAKENHI-PROJECT-18K09009
[Journal Article] Alterations in the corneal nerve and stem/progenitor cells in diabetes : preventive effects of insulin-like growth factor-1 treatment2014
- Author(s)
  Ueno H, Hattori T, Kumagai Y, Suzuki N, Ueno S, Takagi H
- Journal Title
  
  Int J Endocrinol
  
  Volume: 2014 Pages: 312401-312401
- DOI
  10.1155/2014/312401
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23592594, KAKENHI-PROJECT-24791879, KAKENHI-PROJECT-25861657, KAKENHI-PROJECT-26462671
[Journal Article] Trigeminal stereotactic electrolysis induces dry eye in mice.2013
- Author(s)
  Ferrari G,Ueno H, Dana R.
- Journal Title
  
  Acta Ophthalmologica.
  
  Volume: 91 Issue: 2 Pages: 162-163
- DOI
  10.1111/j.1755-3768.2012.02529.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23792015
[Journal Article] Nerves and Neovessels Inhibit Each Other in the Cornea.2013
- Author(s)
  Ferrari G, Ueno H, Dana R
- Journal Title
  
  Invest Ophthalmol Vis Sci.
  
  Volume: 54 Issue: 1 Pages: 813-820
- DOI
  10.1167/iovs.11-8379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23792015
[Journal Article] Imaging of a severe case of acute hydrops in a patient with keratoconus using anterior segment optical coherence tomography.2012
- Author(s)
  Ueno H, Matuzawa A, Kumagai Y, Takagi H, Ueno S
- Journal Title
  
  Case Rep Ophthalmol.
  
  Volume: 3 Issue: 3 Pages: 304-310
- DOI
  10.1159/000337483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592594, KAKENHI-PROJECT-23792015
[Journal Article] Donor-derived, tolerogenic dendritic cells suppress immune rejection in the indrect allosensitization-dominant setting of corneal transplantation2012
- Author(s)
  Hattori T, Ueno H, Dana R.
- Journal Title
  
  J Leukoc Biol.
  
  Volume: 91 (4) Pages: 621-627
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23792015
[Journal Article] Donor-derived, tolerogenic dendritic cells suppress immune rejection in the indirect allosensitization-dominant setting of corneal transplantation2012
- Author(s)
  Takaaki Hattori, Daniel R Saban, Emami-Naeini P, Sunil K. Chauhan, Toshinari Funaki, Hiroki Ueno, Reza Dana
- Journal Title
  
  J Leukoc Biol.
  
  Volume: 91 Issue: 4 Pages: 621-627
- DOI
  10.1189/jlb.1011500
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23792015
[Journal Article] Imaging of a severe case of acute hydrops in a patient with keratoconus2012
- Author(s)
  Ueno H, Kumagai Y, Ueno S.
- Journal Title
  
  Case Reports in Ophthalmology
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23792015
[Journal Article] Dependence of corneal stem/progenitor cells on ocular surface innervation2012
- Author(s)
  Hiroki Ueno, Ferrari Giulio Ferrari, Takaaki Hattori, Daniel R Saban, Katikireddy KR, Sunil K. Chauhan, Reza Dana.
- Journal Title
  
  Invest Ophthalmol Vis Sci.
  
  Volume: 53 Issue: 2 Pages: 867-872
- DOI
  10.1167/iovs.11-8438
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23792015
[Journal Article] Dependence of stem cells on ocular innervation.2012
- Author(s)
  Ueno H, Ferrari G, Hattori T, Dana R.
- Journal Title
  
  Invest Ophthalmol Vis Sci.
  
  Volume: 53 (2) Pages: 867-872
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23792015
[Journal Article] Characterization of Langerin- expressing dendritic cell subsets in the normal cornea2011
- Author(s)
  Takaaki Hattori, Suni K. Chauhan, Hyunsoo Lee, Hiroki Ueno, Reza Dana, Kaplan DH, Daniel R Saban.
- Journal Title
  
  Invest Ophthalmol Vis Sci.
  
  Volume: 52 Issue: 7 Pages: 4598-4604
- DOI
  10.1167/iovs.10-6741
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23792015
[Journal Article] A Novel Mouse Model for Neurotrophic Keratopathy: Trigeminal Nerve Stereotactic Electrolysis through the Brain.2011
- Author(s)
  Giulio Ferrari, Sunil K. Chauhan, Hiroki Ueno, Nambi Nallasamy, Stefano Gandolfi, Lawrence Borges, Reza Dana.
- Journal Title
  
  Invest Ophthalmol Vis Sci
  
  Volume: 52 Issue: 5 Pages: 2532-2539
- DOI
  10.1167/iovs.10-5688
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23792015
[Journal Article] Characterization of Langerin-expressing dendritic cell subsets in the normal cornea.2011
- Author(s)
  Hattori T, Ueno H, Saban DR.
- Journal Title
  
  Invest Ophthalmol Vis Sci.
  
  Volume: 52 (7) Pages: 4598-4604
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23792015
[Journal Article] Transfection with pax6 gene of mouse embryonic stem cells and subsequent cell cloning induced retinal neuron progenitors, including retinal ganglion cell-like cells, in vitro2010
- Author(s)
  Maki Kayama, Manae S. Kurokawa, Yuji Ueda, Hiroki Ueno, Yuta Kumagai, Shunmei Chiba, Erika Takada, Satoki Ueno, Mamoru Tadokoro and Noboru Suzuki.
- Journal Title
  
  Ophthalmic Res.
  
  Volume: 43(2) Issue: 2 Pages: 79-91
- DOI
  10.1159/000247592
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23792015
[Journal Article] Induction of Corneal Epithelium-Like Cells From Cynomolgus Monkey Embryonic Stem Cells and Their Experimental Transplantation to Damaged Cornea2010
- Author(s)
  Yuta Kumagai, Manae S. Kurokawa, Hiroki Ueno, Maki Kayama, Kazuo Tsubota, Norio Nakatsuji, Shinji Nito, Satoki Ueno, Noboru Suzuki
- Journal Title
  
  Cornea
  
  Volume: 29 Issue: 4 Pages: 432-438
- DOI
  10.1097/ico.0b013e3181b9ffcc
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23792015
[Presentation] 角膜実質細胞には骨髄細胞から樹状細胞を誘導する機能がある2016
- Author(s)
  服部貴明、上野宏樹、舟木俊成、後藤浩、Reza Dana
- Organizer
  角膜カンファランス2016
- Place of Presentation
  軽井沢プリンスホテル（長野県・佐久郡）
- Year and Date
  2016-02-18
- Data Source
  KAKENHI-PROJECT-25861657
[Presentation] 角膜実質細胞により骨髄細胞から誘導された樹状細胞の機能解析2016
- Author(s)
  服部貴明、上野宏樹、舟木俊成、後藤浩、Reza Dana
- Organizer
  第120回日本眼科学会
- Place of Presentation
  東北大学（宮城県・仙台市）
- Year and Date
  2016-04-07
- Data Source
  KAKENHI-PROJECT-25861657
[Presentation] 角膜stem/progenitorcellと角膜神経との相互作用について2013
- Author(s)
  上野宏樹
- Organizer
  角膜カンファランス2013シンポジウム
- Place of Presentation
  白浜
- Year and Date
  2013-02-15
- Data Source
  KAKENHI-PROJECT-23792015
[Presentation] EvaluationofCornealProgenitorCellsinMicewithTypeIIDiabetesMellitus2012
- Author(s)
  UenoH,HattoriT,KumagaiY,TakadaE,SuzukiN,UenoS.
- Organizer
  TheAssociationforResearchinvisionandOphthalmology
- Place of Presentation
  FortLauderdale,USA
- Year and Date
  2012-05-08
- Data Source
  KAKENHI-PROJECT-23792015
[Presentation] 角膜stem/progenitorcellと角膜神経との相互作用について2012
- Author(s)
  上野宏樹.
- Organizer
  第16回眼科分子生物学会
- Place of Presentation
  山鹿
- Year and Date
  2012-02-11
- Data Source
  KAKENHI-PROJECT-23792015
[Presentation] 重症円錐角膜急性水腫後前眼部OCTにて長期経過を観察した1例2012
- Author(s)
  上野宏樹、松澤亜紀子、熊谷悠太、高木均、上野聰樹.
- Organizer
  角膜カンファランス2012
- Place of Presentation
  東京
- Year and Date
  2012-02-23
- Data Source
  KAKENHI-PROJECT-23792015
[Presentation] 3者併用療法に希釈ポピドンヨード液を治療に用いたアカントアメーバ角膜炎の3症例2012
- Author(s)
  上野宏樹、松澤亜紀子、熊谷悠太、高木均、上野聰樹
- Organizer
  第66回日本臨床眼科学会
- Place of Presentation
  京都
- Year and Date
  2012-10-27
- Data Source
  KAKENHI-PROJECT-23792015
[Presentation] Evaluation of Corneal Progenitor Cells in a Murine Model of Neurotrophic keratopathy2011
- Author(s)
  Ueno H et al.
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  Fort Lauderdale
- Data Source
  KAKENHI-PROJECT-23792015
[Presentation] EvaluationofCornealProgenitorCellsinaMurineModelofNeurotrophicKeratopathy2011
- Author(s)
  UenoH,FerrariG,HattoriT,UenoS,ChauhanS,DanaR.
- Organizer
  TheAssociationforResearchinvisionandOphthalmology
- Place of Presentation
  FortLauderdale,USA
- Year and Date
  2011-05-04
- Data Source
  KAKENHI-PROJECT-23792015
[Presentation] 高眼圧により視神経変化を伴ったIgG4関連ミクリッツ病の1例2011
- Author(s)
  上野宏樹、熊谷悠太、阿藤晃一、相原正記、高木均、上野聰樹.
- Organizer
  第65回日本臨床眼科学
- Place of Presentation
  東京
- Year and Date
  2011-10-07
- Data Source
  KAKENHI-PROJECT-23792015
[Presentation] NerveRegenerationAssociateWithStemCellEnvironment2010
- Author(s)
  UenoH,FerrariG,HattoriT,FunakiT,SabanD,ChauhanS,DanaR
- Organizer
  TheAssociationforResearchinvisionandOphthalmology
- Place of Presentation
  FortLauderdale,USA
- Year and Date
  2010-05-03
- Data Source
  KAKENHI-PROJECT-23792015
[Presentation] NerveRegenerationDependsonStemCellEnvironment2010
- Author(s)
  UenoH,FerrariG,HattoriT,FunakiT,SabanD,ChauhanS,DanaR.
- Organizer
  TheWorldCorneaCongressVII(WCCVII)
- Place of Presentation
  Boston,USA
- Year and Date
  2010-04-08
- Data Source
  KAKENHI-PROJECT-23792015
[Presentation] Alterations in the corneal nerve in type 2 diabetes: preventive effects of insulin-like growth factor-1 treatment
- Author(s)
  Hiroki Ueno, Takaaki Hattori, Yuta Kumagai, Noboru Suzuki, Satoki Ueno, Hitoshi Takagi
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  アメリカ合衆国　オーランド
- Year and Date
  2014-05-04 – 2014-05-08
- Data Source
  KAKENHI-PROJECT-25861657
[Presentation] 重症2型糖尿病における角膜三叉神経と角膜幹細胞の相互関与
- Author(s)
  上野宏樹
- Organizer
  角膜カンファランス2014
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-25861657
[Presentation] Evaluation of Corneal Progenitor Cells in Mice with Type II Diabetes Mellitus
- Author(s)
  H. Ueno
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  United States: Fort Lauderdale
- Data Source
  KAKENHI-PROJECT-23792015
[Presentation] 角膜神経障害での幹細胞の影響
- Author(s)
  上野宏樹
- Organizer
  角膜カンファランス2013
- Place of Presentation
  和歌山
- Invited
- Data Source
  KAKENHI-PROJECT-23792015
[Presentation] Evaluation of Corneal Stem/Progenitor Cells in leptin deficient mice.
- Author(s)
  Ueno H, Hattori T, Kumagai Y, Suzuki N, Ueno S.
- Organizer
  2013 annual meeting of The Association for Research in Vision and Ophthalmology
- Place of Presentation
  Seattle
- Data Source
  KAKENHI-PROJECT-25861657

1. 上野聰樹 (20109010)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
2. 服部貴明 (20408173)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 鈴木登 (40235982)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 高木均

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Ueno Hiroki 上野 宏樹

UENO Hiroki 上野 宏樹

Research Projects

Research Products

Co-Researchers

角膜三叉神経障害における角膜ミクログリアの役割の解明と治療法開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effects of chronic inflammation with diabetes on corneal stem cells and corneal nervesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effect of the corneal stem/progenitor cells during the corneal inflammatory cell infiltrationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Dependence of corneal stem/progenitor cells on ocular surface innervation.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] アレルギーの臨床2022

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Blockade of costimulatory CD27/CD70 pathway promotes corneal allograft survival2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Interaction between SDF1 and CXCR4 Promotes Photoreceptor Differentiation via Upregulation of NFκB Pathway Signaling Activity in Pax6 Gene-Transfected Photoreceptor Precursors.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Alterations in the corneal nerve and stem/progenitor cells in diabetes : preventive effects of insulin-like growth factor-1 treatment2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Trigeminal stereotactic electrolysis induces dry eye in mice.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nerves and Neovessels Inhibit Each Other in the Cornea.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Imaging of a severe case of acute hydrops in a patient with keratoconus using anterior segment optical coherence tomography.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Donor-derived, tolerogenic dendritic cells suppress immune rejection in the indrect allosensitization-dominant setting of corneal transplantation2012

Author(s)

Journal Title

Data Source

[Journal Article] Donor-derived, tolerogenic dendritic cells suppress immune rejection in the indirect allosensitization-dominant setting of corneal transplantation2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Imaging of a severe case of acute hydrops in a patient with keratoconus2012

Author(s)

Journal Title

Data Source

[Journal Article] Dependence of corneal stem/progenitor cells on ocular surface innervation2012

Author(s)

Journal Title

Ueno Hiroki 上野宏樹

UENO Hiroki 上野宏樹