iseki masanori 井関將典

… Alternative Names

Iseki Masanori 井関將典

ISEKI Masanori 井関將典

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Researcher Number	30532353
Other IDs
Affiliation (Current)	2025: 川崎医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2023 – 2024: 川崎医科大学, 医学部, 講師 2016 – 2021: 川崎医科大学, 医学部, 講師 2015: 国立研究開発法人国立国際医療研究センター, その他部局等, 室長 2011: 独立行政法人国立国際医療研究センター, 免疫制御研究部, 免疫応答修飾研究室長 2011: 独立行政法人国立国際医療研究センター, 免疫制御研究部・免疫応答修飾研究室, 室長 2010: 独立行政法人国立国際医療研究センター, 免疫制御研究部免疫応答修飾研究室, 室長 2009: Research Institute, International Medical Center of Japan, 地域保健医療研究部・地域医療研究室, 室長
Review Section/Research Field	Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related / Basic Section 54030:Infectious disease medicine-related / Gastroenterology / Immunology Except Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related / Experimental pathology
Keywords	Principal Investigator サイトカイン / 自己免疫疾患 / T細胞 / EBI3 / 全身性エリテマトーデス / アトピー性皮膚炎 / TLR / B細胞 / 細胞膜外酵素 / 自然免疫 … More / 抗体産生 / IL-6 / マクロファージ / 辺縁帯B細胞 / 線維化 / IL-5 / 炎症 / 好酸球 / ILC2 / 自然リンパ球 / アレルギー・ぜんそく / 免疫学 / マウスモデル / アレルギー・免疫関連疾患 … More Except Principal Investigator 自己炎症性疾患 / マクロファージ / RNA編集 / VEXAS症候群 / TNF受容体 / ゲノム編集 / 疾患モデルマウス / マウスモデル / TNF / TRAPS / TNF受容体関連周期性症候群 / 自己反応性リンパ球 / 自己抗体 / Imiquimod誘発SLEモデル / Faslprマウス / SLEモデルマウス / 樹状細胞 / Fas-lprマウス / Cherubism / 全身性エリテマトーデス / SH3BP2 / 滑膜 / 関節リウマチモデル / CD38 / BST-1/CD157 / ADPリボシルシクラーゼ / CD157レポーターマウス / CX3CR1 / 単球・マクロファージ亜集団 / マクロファージ様滑膜細胞 / gp130F759 / CD157 / BST-1 / 骨髄系細胞特異的BST-1欠損 / gp130 / Bst1-flox / TLR2 / ROS産生 / 可溶性BST-1 / 血管新生 / IL-6/gp130 / 末梢血単球亜集団 / 滑膜炎 / preclinical phase / 線維化 / 滑膜細胞 / IL-6/gp130/STAT3 / 関節リウマチ / 活性酸素 / Toll様受容体2 / 単球・マクロファージ / 結核 Less

成人自己炎症性疾患VEXAS症候群の病態解明およびCas13を用いた革新的遺伝子治療の開発
- Principal Investigator
  
  向井知之
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Kawasaki Medical School
Mechanisms of reciprocal regulation of immune diseases by EBI3-containing heterodimer cytokinesPrincipal Investigator
- Principal Investigator
  
  井関將典
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Kawasaki Medical School
The investigation of the pathogenesis of TNF receptor-associated periodic syndrome
- Principal Investigator
  
  Hirano Hiroyasu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Kawasaki Medical School
A novel regulatory mechanism for innate immune signals by ectoenzymes BST-1 and CD38Principal Investigator
- Principal Investigator
  
  Iseki Masanori
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Kawasaki Medical School
The role of SH3BP2 in the pathogenesis of systemic lupus eryhematosus
- Principal Investigator
  
  Mukai Tomoyuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Kawasaki Medical School
Roles for CD157 in functions of macrophage lineage cells and early pathophysiology of a rheumatoid arthritis model
- Principal Investigator
  
  Ishihara Katsuhiko
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Kawasaki Medical School
Activation machinery of tissue-resident innate IL-5-producing cells and their roles in inflammatory diseases and fibrosisPrincipal Investigator
- Principal Investigator
  
  Iseki Masanori
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kawasaki Medical School
  National Center for Global Health and Medicine
Analysis of the pathogenic mechanisms of autoimmune diseases induced by overproduction of cytokine TSLPPrincipal Investigator
- Principal Investigator
  
  ISEKI Masanori
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Research Institute, International Medical Center of Japan

All 2024 2023 2021 2020 2019 2018 2017 2016 2015 2012 2011 2010 2009

All Journal Article Presentation

[Journal Article] Co-occurrence of non-alcoholic steatohepatitis exacerbates psoriasis associated with decreased adiponectin expression in a murine model2023
- Author(s)
  Takezaki Daiki、Morizane Shin、Ikeda Kenta、Iseki Masanori、Sakamoto Yuma、Kawakami Yoshio、Hashiguchi Taishi、Shirakata Yuka、Nishina Sohji、Mukai Tomoyuki
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 14 Pages: 1214623-1214623
- DOI
  10.3389/fimmu.2023.1214623
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07917, KAKENHI-PROJECT-21K08484, KAKENHI-PROJECT-22K15426
[Journal Article] Imatinib has minimal effects on inflammatory and osteopenic phenotypes in a murine cherubism model2021
- Author(s)
  Mukai Tomoyuki、Akagi Takahiko、Hiramatsu Asano Sumie、Tosa Ikue、Ono Mitsuaki、Kittaka Mizuho、Ueki Yasuyoshi、Yahagi Ayano、Iseki Masanori、Oohashi Toshitaka、Ishihara Katsuhiko、Morita Yoshitaka
- Journal Title
  
  Oral Diseases
  
  Volume: － Issue: 3 Pages: 0-0
- DOI
  10.1111/odi.14073
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08943, KAKENHI-PROJECT-19H03842, KAKENHI-PROJECT-21K08484, KAKENHI-PROJECT-20K21678
[Journal Article] Distinct physical condition and social behavior phenotypes of CD157 and CD38 knockout mice during aging.2020
- Author(s)
  2.Maria Gerasimenko; Olga Lopatina; Anna A. Shabalova; Stanislav M. Cherepanov; Alla B. Salmina; Shigeru Yokoyama; Hisanori Goto; Hiroshi Okamoto; Yasuhiko Yamamoto; Katsuhiko Ishihara; Haruhiro Higashida.
- Journal Title
  
  PLoS One
  
  Volume: 15(12) Issue: 8 Pages: 4169-4169
- DOI
  10.3390/ijms22084169
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08798, KAKENHI-PROJECT-18K08398, KAKENHI-PROJECT-19K08943, KAKENHI-PROJECT-21K08484
[Journal Article] Functional analysis of a novel G87V TNFRSF1A mutation in patients with TNF receptor-associated periodic syndrome2019
- Author(s)
  Tsuji, S. Matsuzaki, H. Iseki, M. Nagasu, A. Hirano, H. Ishihara, K. Ueda, N. Honda, Y. Horiuchi, T. Nishikomori, R. Morita, Y. Mukai, T.
- Journal Title
  
  Clin Exp Immunol
  
  Volume: 198 Issue: 3 Pages: 416-429
- DOI
  10.1111/cei.13365
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08299, KAKENHI-PROJECT-19K08923, KAKENHI-PROJECT-19K08943, KAKENHI-PROJECT-19H03564
[Journal Article] Sh3bp2 Gain-Of-Function Mutation Ameliorates Lupus Phenotypes in B6.MRL-Faslpr Mice2019
- Author(s)
  Nagasu Akiko、Mukai Tomoyuki、Iseki Masanori、Kawahara Kyoko、Tsuji Shoko、Nagasu Hajime、Ueki Yasuyoshi、Ishihara Katsuhiko、Kashihara Naoki、Morita Yoshitaka
- Journal Title
  
  Cells
  
  Volume: 8 Issue: 5 Pages: 402-402
- DOI
  10.3390/cells8050402
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08398, KAKENHI-PROJECT-19K08943, KAKENHI-PROJECT-18H02828
[Journal Article] IL-6-PAD4 axis in the earliest phase of arthritis in knock-in gp130F759 mice, a model for rheumatoid arthritis2019
- Author(s)
  Yahagi Ayano、Saika Taro、Hirano Hiroyasu、Takai-Imamura Miwa、Tsuji Fumio、Aono Hiroyuki、Iseki Masanori、Morita Yoshitaka、Igarashi Hideya、Saeki Yukihiko、Ishihara Katsuhiko
- Journal Title
  
  RMD Open
  
  Volume: 5 Issue: 2 Pages: e000853-e000853
- DOI
  10.1136/rmdopen-2018-000853
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08798, KAKENHI-PROJECT-19K08943, KAKENHI-PROJECT-17K16217
[Journal Article] Cyclosporin A indirectly attenuates activation of group 2 innate lymphoid cells in papain-induced lung inflammation.2018
- Author(s)
  Kudo F, Ikutani M, Iseki M, Takaki S.
- Journal Title
  
  Cell Immunology
  
  Volume: 323 Pages: 33-40
- DOI
  10.1016/j.cellimm.2017.10.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17KT0132, KAKENHI-PROJECT-15K09036, KAKENHI-PROJECT-16K19111
[Journal Article] Thymic stromal lymphopoietin(TSLP)-induced polyclonal B-cell activation and autoimmunity are mediated by CD4^+T cells and IL-42012
- Author(s)
  Iseki M, Omori-Miyake M, Xu W, Sun X, Takaki S, Rawlings DJ, Ziegler SF
- Journal Title
  
  International Immunology
  
  Volume: Vol.24 Issue: 3 Pages: 183-195
- DOI
  10.1093/intimm/dxr113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790488, KAKENHI-PROJECT-22590446
[Journal Article] Dibutyl Phthalate-Induced Thymic Stromal Lymphopoietin Is Required for Th2 Contact Hypersensitivity Responses2010
- Author(s)
  Larson RP, Zimmerli SC, Comeau MR, Itano A, Omori M, Iseki M, Hauser C, Ziegler SF
- Journal Title
  
  The Journal of Immunology
  
  Volume: Vol.184 Issue: 6 Pages: 2974-2984
- DOI
  10.4049/jimmunol.0803478
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790488
[Presentation] The cytokine component Epstein-Barr virus induced 3 (EBI3) promotes systemic inflammation induced by TLR7 ligand2024
- Author(s)
  Masanori Iseki, Yuma Sakamoto, Daiki Takezaki, Shin Morizane, Tomoyuki Mukai
- Organizer
  第52回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-23K07917
[Presentation] Concomitant Nonalcoholic Steatohepatitis Worsens Psoriasis Associated with Decreased Adiponectin Expression in a Mouse Model2024
- Author(s)
  Daiki Takezaki, Shin Morizane, Kenta Ikeda, Masanori Iseki, Yuma Sakamoto, Yoshio Kawakami, Taishi Hashiguchi, Yuka Shirakata, Sohji Nishina, Tomoyuki Mukai
- Organizer
  第52回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-23K07917
[Presentation] サイトカイン構成要素EBI3はTLR7リガンドによって誘導される全身性炎症を促進する2023
- Author(s)
  井関將典, 坂本祐真, 竹﨑大輝, 森実真, 向井知之
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K07917
[Presentation] 非アルコール性脂肪性肝炎の併存はマウスモデルにおける乾癬を悪化させる2023
- Author(s)
  竹﨑大輝, 森実真, 池田賢太, 井関將典, 坂本佑真, 川上佳夫, 橋口太志, 白方有香, 仁科惣治, 向井知之
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K07917
[Presentation] 非アルコール性脂肪肝炎は乾癬モデルマウスの皮膚IL-23A遺伝子発現を増強する2023
- Author(s)
  竹﨑大輝、森実真、池田賢太、井関將典、坂本佑真、川上佳夫、橋口太志、白方有香、仁科惣治、向井知之
- Organizer
  第122回日本皮膚科学会総会
- Data Source
  KAKENHI-PROJECT-23K07917
[Presentation] Accompanying non-alcoholic steatohepatitis exacerbates psoriasis in a murine model2023
- Author(s)
  Daiki Takezaki, Shin Morizane, Kenta Ikeda, Masanori Iseki, Yuma Sakamoto, Yoshio Kawakami, Taishi Hashiguchi, Yuka Shirakata, Sohji Nishina, and Tomoyuki Mukai
- Organizer
  International Societies for Investigative Dermatology 2023 (ISID 2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07917
[Presentation] 関節リウマチモデルgp130F759の最初期滑膜細胞におけるシングルセルRNA-seq解析2021
- Author(s)
  矢作綾野、井関將典、石原克彦
- Organizer
  第65回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17K08798
[Presentation] Lack of bone marrow stromal cell antigen-1 (BST-1)/CD157 ameliorated colitis induced by dextran sodium sulfate (DSS)2021
- Author(s)
  Katsuhiko Ishihara , Ayano Yahagi , Masanori Iseki , Ryo Katsumata , Akiko Shiotani
- Organizer
  Virtual Immunology 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08798
[Presentation] 関節リウマチモデルgp130F759の最初期滑膜細胞のシングルセルRNA-seq解析2021
- Author(s)
  矢作綾野、井関將典、石原克彦
- Organizer
  第65回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K08943
[Presentation] The investigation of the pathogenesis of TNF Receptor-Associated Periodic Syndrome (TRAPS) using murine TRAPS models2021
- Author(s)
  赤木貴彦, 向井知之, 浅野澄恵, 井関將典, 矢作綾野, 平野紘康, 中野和久, 石原克彦, 守田吉孝
- Organizer
  The 50th Annual Meeting of the Japanese Society for Immunology（JSI2021）
- Data Source
  KAKENHI-PROJECT-19K08943
[Presentation] Lack of bone marrow stromal cell antigen-1 (BST-1)/CD157 ameliorated colitis induced by dextran sodium sulfate (DSS)2021
- Author(s)
  Katsuhiko Ishihara, Ayano Yahagi, Ryo Katsumata, Akiko Shiotani, Masanori Iseki
- Organizer
  VIRTUAL IMMUNOLOGY2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08943
[Presentation] 関節リウマチモデルgp130F759の最初期病変におけるIL-6-PAD4連関2020
- Author(s)
  矢作綾野、井関將典、石原克彦
- Organizer
  第64回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K08943
[Presentation] SH3BP2 deficiency ameliorates murine systemic lupus erythematosus2020
- Author(s)
  Tomoyuki Mukai, Kyoko Kawahara, Masanori Iseki, Akiko Nagasu, Hajime Nagasu, Takahiko Akagi, Shoko Tsuji, Yasuyoshi Ueki, Katsuhiko Ishihara, Naoki Kashihara, Yoshitaka Morita
- Organizer
  The 22nd Asia Pacific League of Associations for Rheumatology (APLAR 2020)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08398
[Presentation] BST-1/CD157の欠損による滑膜線維芽細胞のIL-6産生低下により、GP130F759の関節炎における線維化が軽減した。2020
- Author(s)
  石原克彦, 矢作綾野, 井関將典
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08798
[Presentation] BST-1/CD157の欠損による滑膜線維芽細胞のIL-6産生低下により、GP130F759の関節炎における線維化が軽減した。2020
- Author(s)
  石原克彦, 矢作綾野, 井関將典
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K08943
[Presentation] 全身性エリテマトーデスモデルマウスにおけるアダプター蛋白SH3BP2 の自己免疫現象における役割の解明2020
- Author(s)
  河原恭子,　向井知之,　井関將典,　長洲晶子,　長洲一,　赤木貴彦,　辻尚子,　石原克彦,　柏原直樹,　植木靖好,　守田吉孝
- Organizer
  第41回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-18K08398
[Presentation] SH3BP2 Deficiency Ameliorates Murine Systemic Lupus Erythematosus2020
- Author(s)
  Tomoyuki Mukai , Kyoko Kawahara , Masanori Iseki , Akiko Nagasu , Hajime Nagasu , Takahiko Akagi , Shoko Tsuji , Yasuyoshi Ueki , Katsuhiko Ishihara , Naoki Kashihara and Yoshitaka Morita
- Organizer
  2020 American College of Rheumatology(ACR) Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08398
[Presentation] BST-1/CD157はDSS誘発性大腸炎における腸上皮の傷害を促進させる2020
- Author(s)
  矢作綾野、井関將典、石原克彦
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08798
[Presentation] BST-1/CD157はDSS誘発性大腸炎における腸上皮の傷害を促進させる2020
- Author(s)
  矢作綾野、井関將典、石原克彦
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K08943
[Presentation] 関節リウマチモデルgp130F759の最初期病変におけるIL-6-PAD4連関 -滑膜線維芽細胞と好中球の相互作用-2020
- Author(s)
  矢作綾野、井関將典、石原克彦
- Organizer
  第64回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17K08798
[Presentation] The role of an adaptor protein SH3BP2 in the pathogenesis of systemic lupus erythematosus2020
- Author(s)
  Tomoyuki Mukai, Kyoko Kawahara, Masanori Iseki, Akiko Nagasu, Hajime Nagasu, Takahiko Akagi, Shoko Tsuji, Sumie Asano, Yasuyoshi Ueki, Katsuhiko Ishihara, Naoki Kashihara, Yoshitaka Morita
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K08398
[Presentation] IL-6-PAD4 axis: IL-6 dependent PAD4 production in neutrophils at the earliest phase of arthritis in gp130F759.2019
- Author(s)
  Ayano Yahagi, Taro Saika, Masanori Iseki, Katsuhiko Ishihara
- Organizer
  The 48th Annual Meeting of the Japanese for Immunology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08798
[Presentation] The Study of the Novel G87V Mutation in the TNFRSF1A Gene Identified in a Family with TNF Receptor-Associated Periodic Syndrome (TRAPS)2019
- Author(s)
  Shoko Tsuji, Hidenori Matsuzaki, Masanori Iseki, Akiko Nagasu, Hiroyasu Hirano, Katsuhiko Ishihara, Naoyasu Ueda, Yoshitaka Honda, Takahiko Horiuchi, Ryuta Nishikomori, Yoshitaka Morita, Tomoyuki Mukai
- Organizer
  2019 American College of Rheumatology(ACR) Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08923
[Presentation] SH3BP2 gain-of-function mutation ameliorates lupus in B6.MRL-Faslpr mice2019
- Author(s)
  Akiko Nagasu, Tomoyuki Mukai, Masanori Iseki, Hajime Nagasu, Kyoko Kawahara, Shoko Tsuji, Shunichi Fujita, Naoki Kashihara, Katsuhiko Ishihara, Yoshitaka Morita
- Organizer
  The 63rd Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology
- Data Source
  KAKENHI-PROJECT-18K08398
[Presentation] Toll-like receptor-induced Ab production from marginal zone B cells is negatively regulated by ADP-ribosyl cyclase BST-1/CD1572019
- Author(s)
  Masanori Iseki, Ayano Yahagi, Katsuhiko Ishihara
- Organizer
  The 48th Annual Meeting of the Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-19K08943
[Presentation] The role of adopter protein SH3BP2 in a murine systemic lupus erythematosus model2019
- Author(s)
  Kyoko Kawahara,　Tomoyuki Mukai,　Akiko Nagasu,　Masanori Iseki,　Hajime Nagasu,　Shoko Tsuji,　Takahiko Akagi,　Yasuyoshi Ueki,　Yoshitaka Morita
- Organizer
  2019 American College of Rheumatology(ACR) Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08398
[Presentation] The Study of the novel G58V mutation in the TNFRSF1A gene identified in a family with TNF Receptor-Associated Periodic Syndrome(TRAPS)2019
- Author(s)
  Shoko Tsuji, Tomoyuki Mukai, Akiko Nagasu, Hiroyasu Hirano, Masanori Iseki, Takahiro Horiuchi, Ryuta Nishikomori, Yoshitaka Morita
- Organizer
  The 63rd Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology
- Data Source
  KAKENHI-PROJECT-19K08923
[Presentation] CX3CR1-eGFP+macrophage-like synoviocytes in gp130F759, a mouse model for rheumatoid arthritis2019
- Author(s)
  Ayano Yahagi, Yujiro Yokoyama, Noritaka Tsunematsu, Masanori Iseki, Katsuhiko Ishihara.
- Organizer
  The 26th International Symposium on Molecular Cell Biology of Macrophages
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08798
[Presentation] TNF受容体関連周期性症候群 (TRAPS) 患者におけるG87V変異 TNFRSF1Aの同定と機能解析2019
- Author(s)
  向井知之, 辻尚子, 松崎秀紀, 井関將典, 長洲晶子, 平野紘康, 石原克彦, 上田尚靖, 本田吉孝, 堀内孝彦, 西小森隆太, 守田　吉孝
- Organizer
  第47回日本臨床免疫学会総会
- Data Source
  KAKENHI-PROJECT-19K08923
[Presentation] 全身性エリテマトーデスモデルマウスにおけるアダプター蛋白SH3BP2の自己免疫現象に対する役割の解明2019
- Author(s)
  河原恭子, 向井知之, 長洲晶子, 井関將典, 赤木貴彦, 長洲一, 植木靖好, 守田吉孝
- Organizer
  第47回日本臨床免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08398
[Presentation] 全身性エリテマトーデスモデルマウスにおけるアダプタータンパクSH3BP2の役割の解明2019
- Author(s)
  河原恭子, 向井知之, 長洲晶子, 井関將典, 赤木貴彦, 長洲一, 植木靖好, 守田吉孝
- Organizer
  第84回日本インターフェロン・サイトカイン学会
- Data Source
  KAKENHI-PROJECT-18K08398
[Presentation] Toll-like receptor-induced Ab production from marginal zone B cells is negatively regulated by ADP-ribosyl cyclase BST-1/CD1572019
- Author(s)
  Masanori Iseki, Ayano Yahagi, Katsuhiko Ishihara
- Organizer
  The 48th Annual Meeting of the Japanese Society for Immunology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08798
[Presentation] 全身性エリテマトーデスモデルマウスにおけるアダプタータンパクSH3BP2の自己免疫現象に対する役割の解明2019
- Author(s)
  河原恭子,　向井知之,　長洲晶子,　井関　將典,　赤木貴彦,　長洲一,　植木靖好,　守田吉孝
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08398
[Presentation] Deletion of padi4 exacerbated the arthritis in gp130F759.2018
- Author(s)
  Ayano Yahagi, Masanori Iseki, Kazuhiko Yamamoto, Katsuhiko Ishihara
- Organizer
  The 47th Annual Meeting of the Japanese Society for Immunology, Fukuoka
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08798
[Presentation] A novel function of ADP-ribosyl cyclases to regulate the length of the small intestine revealed in CD38/CD157 double knockout mice.2018
- Author(s)
  Katsuhiko Ishihara, Ayano Yahagi, Masanori Iseki
- Organizer
  IMMUNOLOGY 2018, 2018.5.4-8, Austin,Texas
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08798
[Presentation] BST-1/CD157 negatively regulates marginal zone B cell survival and Ab production induced with Toll-like receptor stimulation2018
- Author(s)
  Masanori Iseki, Ayano Yahagi, Katsuhiko Ishihara
- Organizer
  The 47th Annual Meeting of the Japanese Society for Immunology, Fukuoka
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08798
[Presentation] Elongation of the small intestine and enlargement of the mesenteric lymph nodes in Bst1Cd38 double knockout mice.2018
- Author(s)
  Katsuhiko Ishihara, Ayano Yahagi, Masanori Iseki
- Organizer
  The 47th Annual Meeting of the Japanese Society for Immunology, Fukuoka
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08798
[Presentation] BST-1/CD157 on B cells negatively regulates Toll-like receptor signaling2017
- Author(s)
  Masanori Iseki, Ayano Yahagi, Katsuhiko Ishihara
- Organizer
  The 46th Annual Meeting of The Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-15K09036
[Presentation] BST-1/CD157 on B cells negatively regulates Toll-like receptor signaling2017
- Author(s)
  Masanori Iseki, Ayano Yahagi, Katsuhiko Ishihara
- Organizer
  第46回日本免疫学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08798
[Presentation] Lack of microbiota revealed the role for BST-1/CD157 to maintain the homeostasis at mucosa-MLN interface2016
- Author(s)
  Katsuhiko ISHIHARA, Ayano YAHAGI, Takaaki NISHIMOTO, Masanori ISEKI
- Organizer
  The 45th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  沖縄コンベンションセンター（沖縄県宜野湾市）
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15K09036
[Presentation] Lnk/Sh2bファミリーアダプター分子Aps/Sh2b2による胚中心形成およびIgE産生制御2015
- Author(s)
  井関將典、工藤藤美、高木智
- Organizer
  第1回3NC合同リトリート
- Place of Presentation
  国立国際医療研究センター（戸山）
- Year and Date
  2015-08-18
- Data Source
  KAKENHI-PROJECT-15K09036
[Presentation] Germinal center B cell survivial and optimal IgE production are controled by Lnk/Sh2b family adaptor protein Aps/Sh2b22015
- Author(s)
  井関將典、工藤藤美、高木智
- Organizer
  第44回日本免疫学会総会・学術集会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K09036
[Presentation] セリアック病及び1型糖尿病関連遺伝子Lnk/Sh2b3欠損はCD8+T細胞による腸管絨毛の炎症性萎縮をおこす2011
- Author(s)
  安楽正輝、井関将典、高木智, 他
- Organizer
  日本免疫学会総会・学術集会
- Place of Presentation
  幕張メッセ(千葉)
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-21790488
[Presentation] Expression and function of MafB, a target transcription factor of Btk-mediated signaling in B cells and its relation to autoimmunity2011
- Author(s)
  福田誠、井関将典、高木智, 他
- Organizer
  日本免疫学会総会・学術集会
- Place of Presentation
  幕張メッセ(千葉)
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-21790488
[Presentation] IgE-specific impairment in humoral immune responses by the absence of Aps/Sh2b2, a member of Lnk/Sh2b adaptor family2011
- Author(s)
  Iseki M, Takaki S
- Organizer
  第40回日本免疫学会総会・学術集会
- Place of Presentation
  幕張メッセ(千葉)
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-21790488
[Presentation] An autoimmune disease-associated gene, Lnk/Sh2b3 controls signaling of inflammatory cytokines in dendritic cells and regulates regulatory T and helper T cell development2011
- Author(s)
  森泰三、井関将典、高木智, 他
- Organizer
  日本免疫学会総会・学術集会
- Place of Presentation
  幕張メッセ(千葉)
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-21790488
[Presentation] IgE-specific impairment in humoral immune responses by the absence of Aps/Sh2b2, a member of Lnk/Sh2b adaptor family2011
- Author(s)
  井関将典、高木智
- Organizer
  日本免疫学会総会・学術集会
- Place of Presentation
  幕張メッセ(千葉)
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-21790488
[Presentation] Lnk/SH2B3, a gene associated with risk of several autoimmune diseases regulates proliferation and retinoic acid production of dendritic cells2010
- Author(s)
  岩崎由希子、井関將典, 他
- Organizer
  International Congress of Immunology 2010
- Place of Presentation
  神戸ポートピアホテル神戸国際展示場(神戸)
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-21790488
[Presentation] Thymic stromal lymphopoietin(TSLP)-induced polyclonal B cell activation and autoimmunity are mediated by CD4^+T cells and IL-42010
- Author(s)
  Iseki M, Omori-Miyake M, Xu W, Sun X, Takaki S, Rawlings DJ, Ziegler SF
- Organizer
  International Congress of Immunology 2010
- Place of Presentation
  神戸ポートピアホテル、神戸国際展示場(神戸)
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-21790488
[Presentation] The maintenance of gut-associated lymphoid tissues regulated by Lnk/Sh2B3 adaptor, a shared risk factor gene associated with type 1 diabetes and celiac disease2010
- Author(s)
  片山緩子、井関將典, 他
- Organizer
  International Congress of Immunology 2010
- Place of Presentation
  神戸ポートピアホテル神戸国際展示場(神戸)
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-21790488
[Presentation] Thymic stromal lymphopoietin (TSLP)-induced polyclonal B cell activation and autoimmunity are mediated by CD4+ T cells and IL-42010
- Author(s)
  井関將典, 他
- Organizer
  International Congress of Immunology 2010
- Place of Presentation
  神戸ポートピアホテル神戸国際展示場(神戸)
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-21790488
[Presentation] TSLP modulates TH1 and TH2 responses in the skin2010
- Author(s)
  Ryan P.Larson、井関將典, 他
- Organizer
  International Congress of Immunology 2010
- Place of Presentation
  神戸ポートピアホテル神戸国際展示場(神戸)
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-21790488
[Presentation] Thymic atromal lymphapoietin (TSLP)-iaduced polyclonal B cell activation and autoimmunity are mediated bY CD4+ T cells and IL-42009
- Author(s)
  井関將典, 他
- Organizer
  第39回日本免疫学会総会・学術集会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-21790488
[Presentation] Thymic stromal lymphopoietin(TSLP)-induced polyclonal B cell activation and autoimmunity are mediated by CD4^+T cells and IL-42009
- Author(s)
  Iseki M, Omori-Miyake M, Shih WX, Sun X, Rawlings DJ, Ziegler SF
- Organizer
  第39回日本免疫学会総会・学術集会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-21790488

1. Mukai Tomoyuki (00454421)

# of Collaborated Projects: 4 results

# of Collaborated Products: 20 results
2. Ishihara Katsuhiko (10263245)

# of Collaborated Projects: 2 results

# of Collaborated Products: 23 results
3. 矢作綾野 (10584873)

# of Collaborated Projects: 2 results

# of Collaborated Products: 22 results
4. 守田吉孝 (50346441)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
5. Hirano Hiroyasu (10454828)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. 高木智 (10242116)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. 長洲一 (40412176)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
8. 松崎秀紀 (80335463)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 近藤英生 (30379747)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 伊藤達男 (80789123)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 清水由梨香 (80963355)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 坂本祐真 (90865817)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 森実真 (80423333)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
14. 西小森隆太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

iseki masanori 井関 將典

Iseki Masanori 井関 將典

ISEKI Masanori 井関 將典

Research Projects

Research Products

Co-Researchers

成人自己炎症性疾患VEXAS症候群の病態解明およびCas13を用いた革新的遺伝子治療の開発

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Mechanisms of reciprocal regulation of immune diseases by EBI3-containing heterodimer cytokinesPrincipal Investigator

Principal Investigator

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The investigation of the pathogenesis of TNF receptor-associated periodic syndrome

Principal Investigator

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A novel regulatory mechanism for innate immune signals by ectoenzymes BST-1 and CD38Principal Investigator

Principal Investigator

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The role of SH3BP2 in the pathogenesis of systemic lupus eryhematosus

Principal Investigator

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Review Section

Research Institution

Roles for CD157 in functions of macrophage lineage cells and early pathophysiology of a rheumatoid arthritis model

Principal Investigator

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Activation machinery of tissue-resident innate IL-5-producing cells and their roles in inflammatory diseases and fibrosisPrincipal Investigator

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Analysis of the pathogenic mechanisms of autoimmune diseases induced by overproduction of cytokine TSLPPrincipal Investigator

Principal Investigator

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[Journal Article] Co-occurrence of non-alcoholic steatohepatitis exacerbates psoriasis associated with decreased adiponectin expression in a murine model2023

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[Journal Article] Imatinib has minimal effects on inflammatory and osteopenic phenotypes in a murine cherubism model2021

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[Journal Article] Distinct physical condition and social behavior phenotypes of CD157 and CD38 knockout mice during aging.2020

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[Journal Article] Functional analysis of a novel G87V TNFRSF1A mutation in patients with TNF receptor-associated periodic syndrome2019

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[Journal Article] Sh3bp2 Gain-Of-Function Mutation Ameliorates Lupus Phenotypes in B6.MRL-Faslpr Mice2019

Author(s)

Journal Title

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Data Source

[Journal Article] IL-6-PAD4 axis in the earliest phase of arthritis in knock-in gp130F759 mice, a model for rheumatoid arthritis2019

iseki masanori 井関將典

Iseki Masanori 井関將典

ISEKI Masanori 井関將典