Kurose Koji 黒瀬浩史

Researcher Number	30551139
Other IDs
Affiliation (Current)	2025: 川崎医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2022 – 2025: 川崎医科大学, 医学部, 講師 2019 – 2020: 川崎医科大学, 医学部, 講師 2016 – 2018: 川崎医科大学, 医学部, 助教 2017: 川崎医科大学, 医学部・呼吸器内科学, 臨床助教
Review Section/Research Field	Principal Investigator Basic Section 53030:Respiratory medicine-related / Basic Section 50010:Tumor biology-related / Tumor biology Except Principal Investigator Basic Section 53030:Respiratory medicine-related / Tumor therapeutics
Keywords	Principal Investigator Treg / 血清NY-ESO-1/XAGE1抗体 / 免疫チェックポイント阻害薬 / バイオマーカー / がん精巣抗原 / XAGE1 / NY-ESO-1 / NSCLC / TAA / cancer-testis antigens … More / 化学療法 / がん免疫微小環境 / がん性胸水 / 免疫チェックポイント分子 / 癌性胸水 / 肺がん / 非小細胞肺癌 / 腫瘍浸潤リンパ球 / TIM-3 / PD-1 / PD-L1 / 制御性T細胞 / 肺癌微小環境 … More Except Principal Investigator がん抗原 / モニタリング / バイオマーカー / がん免疫療法 / 免疫活性化 / 癌 / 免疫チェックポイント / Galectin-9 / TIM-3 / PD-1 / XAGE1 / 肺癌 / 免疫チェックポイント分子 / 免疫療法 / 肺がん Less

肺腺がん特異的に発現するXAGE1抗原を標的にした診断薬と治療法の特許開発Principal Investigator
- Principal Investigator
  
  黒瀬浩史
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Kawasaki Medical School
肺がん免疫療法の効果をモニタリングする血清マーカーの特許開発
- Principal Investigator
  
  岡三喜男
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Kawasaki Medical School
肺がん免疫療法の効果を予測する多抗原性血清抗体検出パネルの臨床開発Principal Investigator
- Principal Investigator
  
  黒瀬浩史
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Kawasaki Medical School
Tumor immune microenvironment reviving chemotherapy sensitivity in lung cancerPrincipal Investigator
- Principal Investigator
  
  KUROSE KOJI
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kawasaki Medical School
Identification of tumor microenvironment involving tumor infiltrating regulatory T cells in lung cancerPrincipal Investigator
- Principal Investigator
  
  Kurose Koji
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Kawasaki Medical School
Identification of immunosuppressive factor in tumor microenvironment in patient with lung cancer
- Principal Investigator
  
  Ohue Yoshihiro
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Kawasaki Medical School

All 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Immune checkpoint therapy and response biomarkers in non-small-cell lung cancer: Serum NY-ESO-1 and XAGE1 antibody as predictive and monitoring markers2023
- Author(s)
  Kurose Koji、Sakaeda Kanako、Fukuda Minoru、Sakai Yumiko、Shimizu Katsuhiko、Tanaka Ryo、Hasegawa Takehiro、Atarashi Yusuke、Irino Yasuhiro、Sato Toshiyuki、Inoue Hiromasa、Hattori Noboru、Kanda Eiichiro、Nakata Masao、Mukae Hiroshi、Oga Toru、Oka Mikio
- Journal Title
  
  Advances in Clinical Chemistry
  
  Volume: 112 Pages: 155-204
- DOI
  10.1016/bs.acc.2022.09.004
- ISBN
  9780443192845
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08247, KAKENHI-PROJECT-22K08346
[Journal Article] A novel automated immunoassay for serum NY-ESO-1 and XAGE1 antibodies in combinatory prediction of response to anti-programmed cell death-1 therapy in non-small-cell lung cancer2021
- Author(s)
  Sakai Yumiko、Kurose Koji、Sakaeda Kanako、Abo Hirotaka、Atarashi Yusuke、Ide Nobuyuki、Sato Toshiyuki、Kanda Eiichiro、Fukuda Minoru、Oga Toru、Noda Kenta、Oka Mikio
- Journal Title
  
  Clinica Chimica Acta
  
  Volume: 519 Pages: 51-59
- DOI
  10.1016/j.cca.2021.04.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15226
[Journal Article] Serum Antibody Against NY-ESO-1 and XAGE1 Antigens Potentially Predicts Clinical Responses to Anti?Programmed Cell Death-1 Therapy in NSCLC2019
- Author(s)
  Ohue Yoshihiro、Kurose Koji、Karasaki Takahiro、Isobe Midori、Yamaoka Takaaki、Futami Junichiro、Irei Isao、Masuda Takeshi、Fukuda Masaaki、Kinoshita Akitoshi、Matsushita Hirokazu、Shimizu Katsuhiko、Nakata Masao、Hattori Noboru、Yamaguchi Hiroyuki、Fukuda Minoru、Nozawa Ryohei、Kakimi Kazuhiro、Oka Mikio
- Journal Title
  
  Journal of Thoracic Oncology
  
  Volume: 14 Issue: 12 Pages: 2071-2083
- DOI
  10.1016/j.jtho.2019.08.008
- NAID
  120006796543
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15226, KAKENHI-PROJECT-18H02696, KAKENHI-PROJECT-19H03528, KAKENHI-PROJECT-19H03729, KAKENHI-PROJECT-17K10778, KAKENHI-PROJECT-18K07306
[Journal Article] NY-ESO-1 Protein Cancer Vaccine With Poly-ICLC and OK-432: Rapid and Strong Induction of NY-ESO-1-specific Immune Responses by Poly-ICLC2017
- Author(s)
  Takeoka T, Nagase H, Kurose K, Ohue Y, Yamasaki M, Takiguchi S, Sato E, Isobe M, Kanazawa T, Matsumoto M, Iwahori K, Kawashima A, Morimoto-Okazawa A, Nishikawa H, Oka M, Pan L, Venhaus R, Nakayama E, Mori M, Doki Y, Wada H.
- Journal Title
  
  J Immunother
  
  Volume: epub Issue: 4 Pages: 140-147
- DOI
  10.1097/cji.0000000000000162
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18463, KAKENHI-PROJECT-26290054, KAKENHI-PROJECT-15K09235, KAKENHI-PROJECT-16K21533, KAKENHI-PROJECT-16K15551, KAKENHI-PROJECT-17H06162
[Journal Article] Nivolumab-induced polyarthritis.2017
- Author(s)
  Kodama S, Kurose K, Mukai T, Morita Y.
- Journal Title
  
  BMJ Case Rep.
  
  Volume: - Pages: bcr-2017-223387
- DOI
  10.1136/bcr-2017-223387
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K21533
[Journal Article] Survival of Lung Adenocarcinoma Patients Predicted from Expression of PD-L1, Galectin-9, and XAGE1 (GAGED2a) on Tumor Cells and Tumor-Infiltrating T Cells.2016
- Author(s)
  Ohue Y, Kurose K, Nozawa R, Isobe M, Nishio Y, Tanaka T, Doki Y, Hori T, Fukuoka J, Oka M, Nakayama E
- Journal Title
  
  Cancer Immunology Research
  
  Volume: 4 Pages: 1049-1060
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K21533
[Journal Article] Survival of Lung Adenocarcinoma Patients Predicted from Expression of PD-L1, Galectin-9, and XAGE1 (GAGED2a) on Tumor Cells and Tumor-Infiltrating T Cells2016
- Author(s)
  Ohue Y, Kurose K, Nozawa R, Isobe M, Nishio Y, Tanaka T, Doki Y, Hori T, Fukuoka J, Oka M, Nakayama E.
- Journal Title
  
  Cancer Immunol Res
  
  Volume: 12 Pages: 1049-1060
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K18463
[Presentation] 非小細胞肺がんの周術期におけるがん免疫応答の解析　周術期免疫チェックポイント療法の血清バイオマーカー開発へ向けて2023
- Author(s)
  黒瀬浩史、清水克彦、最相晋輔、榮田佳那子、阪井裕美子、柳田匡俊、佐藤利幸、小賀徹、中田昌男、岡三喜男
- Organizer
  第20回日本免疫治療学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08247
[Presentation] 肺がん免疫チェックポイント療法の効果を予測する血清バイオマーカーの全自動測定法の開発2023
- Author(s)
  黒瀬浩史、渡辺安奈、福田実、菅崎七枝、木下明敏、北崎健、福田正明、益田武、竹本真之輔、松村勇輝、武藤哲史、榮田佳那子、新勇介、佐藤利幸、服部登、迎寛、鈴木弘行、小賀徹、岡三喜男
- Organizer
  第64回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08247
[Presentation] 非小細胞肺癌における免疫チェックポイント阻害薬の効果を予測する自動化測定法の開発2023
- Author(s)
  黒瀬浩史、福田実、北崎健、福田正明、菅崎七枝、木下明敏、益田武、服部登、竹本真之輔、榮田佳那子、新勇介、佐藤利幸、迎寛、小賀徹、岡三喜男
- Organizer
  第63回日本呼吸器学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08247
[Presentation] 肺がん免疫チェックポイント療法の効果をモニタリングする血清バイオマーカーの開発2022
- Author(s)
  黒瀬浩史、福田　実、菅崎七枝、木下明敏、北崎　健、福田正明、竹本真之輔、山口博之、最相晋輔、清水克彦、榮田佳那子、新　勇介、入野康宏、佐藤利幸、中田昌男、迎　寛、小賀　徹、岡　三喜男
- Organizer
  第63回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08247
[Presentation] 非小細胞肺がんの抗PD-1抗体療法の効果を予測するバイオマーカー測定試薬の開発2021
- Author(s)
  黒瀬浩史、福田実、北崎健、福田正明、菅崎七枝、木下明敏、竹本真之輔、山口博之、榮田佳那子、新勇介、野田健太、佐藤利幸、迎寛、小賀徹、岡三喜男
- Organizer
  第61回日本呼吸器学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15226
[Presentation] 肺腺癌患者に対するXAGE1長鎖ペプチドを用いたワクチン治療の安全性と免疫原性に関する試験（第I相臨床試験）2020
- Author(s)
  黒瀬浩史、大植祥弘、頼住昇、田中仁美、八十川直哉、阿部公亮、吉岡大介、小賀徹、岡三喜男
- Organizer
  第17回日本免疫治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15226
[Presentation] 非小細胞肺がんの抗PD-1療法の効果を予測およびモニタリングするバイオマーカー検査薬の開発2020
- Author(s)
  黒瀬浩史、大植祥弘、福田正明、木下明敏、益田武、服部登、福田実、迎寛、小賀徹、岡三喜男
- Organizer
  第60回日本呼吸器学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15226
[Presentation] 非小細胞肺がんの抗PD-1抗体療法の効果をモニタリングする血清バイオマーカー2020
- Author(s)
  黒瀬浩史、福田実、福田正明、木下明敏、益田武、服部登、清水克彦、中田昌男、竹本真之輔、山口博之、迎寛、小賀徹、岡三喜男
- Organizer
  第61回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15226
[Presentation] Serum Antibody against NY-ESO-1 and XAGE1 Predicts Clinical Responses2019
- Author(s)
  黒瀬浩史、大植祥弘、唐崎隆弘、益田武、松下博和、山口博之、福田実、垣見和宏、岡三喜男
- Organizer
  第16回日本免疫治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15226
[Presentation] 肺腺癌患者に対するXAGE1長鎖ペプチドを用いたワクチン治療の安全性と免疫原性に関する試験（第I相臨床試験）2019
- Author(s)
  黒瀬浩史、大植祥弘、頼住昇、田中仁美、八十川直哉、橘髙誠、阿部公亮、吉岡大介、加藤茂樹、小橋吉博、小賀徹、岡三喜男
- Organizer
  第60回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15226
[Presentation] 非小細胞肺がんの免疫チェックポイント療法の効果を予測およびモニタリングする新規バイオマーカーの開発2019
- Author(s)
  黒瀬浩史、大植祥弘、唐崎隆弘、福田正明、木下明敏、益田武、服部登、清水克彦、中田昌男、山岡誉明、二見淳一郎、山口博之、福田実、垣見和宏、岡三喜男
- Organizer
  第23回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K15226
[Presentation] Serum antibody against NY-ESO-1 and XAGE1 predicts clinical responses to anti-PD-1 therapy in non-small-cell lung cancer2018
- Author(s)
  Koji Kurose, Yoshihiro Ohue, Takahiro Karasaki, Junichiro Futami, Isao Irei, Takeshi Masuda, Masaaki Fukuda, Akitoshi Kinoshita, Hirokazu Matsushita, Katsuhiko Shimizu, Hiroyuki Yamaguchi, Minoru Fukuda, Kazuhiro Kakimi, and Mikio Oka
- Organizer
  Fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15226
[Presentation] Reviving chemotherapy sensitivity after anti-CCR4 mAb (mogamulizumab) treatment in lung cancer patients2018
- Author(s)
  黒瀬　浩史, 大植　祥弘, 磯辺　みどり, 鈴木　進, 和田　尚, 上田　龍三, 中山　睿一, 岡　三喜男
- Organizer
  第15回日本免疫治療学研究会学術集会
- Data Source
  KAKENHI-PROJECT-16K21533
[Presentation] Reviving chemotherapy sensitivity after anti-CCR4 mAb (mogamulizumab) treatment in lung cancer patients2017
- Author(s)
  Kurose K, Ohue Y, Isobe M, Suzuki S, Wada H, Oka M, Ueda R, Nakayama E.
- Organizer
  Third CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21533
[Presentation] Reviving chemotherapy sensitivity after anti-CCR4 mAb (mogamulizumab) treatment in lung cancer patients2017
- Author(s)
  Koji Kurose, Yoshihiro Ohue, Midori Isobe, Susumu Suzuki, Hisashi Wada, Ryuzo Ueda, Eiichi Nakayama and Mikio Oka
- Organizer
  IASLC 18th world conference on lung cancer(WCLC 2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21533
[Presentation] Correlation of Clinical Response and XAGE1 Immunity in Lung Adenocarcinoma.2017
- Author(s)
  Ohue Y, Kurose K, Isobe M, Fukuda M, Nakayama E, Oka M
- Organizer
  IASLC 18th World Conference on Lung Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18463
[Presentation] Reviving Chemotherapy Sensityvity after Anti-CCR4 mAb (Mogamulizumab) Treatment in Lung Cancer Patients.2017
- Author(s)
  Kurose K, Ohue Y, Isobe M, Suzuki S, Wada H, Ueda R, Nakayama E, Oka M.
- Organizer
  IASLC 18th World Conference on Lung Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18463
[Presentation] Immuno-inhibitory pathway, TIM-3/Galectin-9, in lung adenocarcinoma: clinical and in vitro analysis.2017
- Author(s)
  Oka M, Ohue Y, Kurose K, Nishio Y, Isobe M, Nakayama E.
- Organizer
  101st Annual Meeting of American Association of Cancer Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18463
[Presentation] 肺腺癌のTIM-3/Galectin-9経路を介した免疫抑制と予後の関連2016
- Author(s)
  大植祥弘, 黒瀬浩史, 磯辺みどり, 西尾祐美, 岡三喜男, 中山睿一
- Organizer
  第20回日本がん免疫学会総会
- Place of Presentation
  大阪国際交流センター（大阪）
- Data Source
  KAKENHI-PROJECT-16K18463
[Presentation] 腫瘍PD-L1,Gal-9,XAGE1発現及びT細胞浸潤を指標とした肺腺癌の予後予測2016
- Author(s)
  大植祥弘, 黒瀬浩史, 西尾祐美, 磯辺みどり, 福岡順也, 中山睿一, 岡三喜男
- Organizer
  第56回日本呼吸器学会学術講演会
- Place of Presentation
  京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-16K18463
[Presentation] Role of TIM-3/Galectin-9 pathway in lung adenocarcinoma2016
- Author(s)
  Ohue Y, Kurose K, Nishio Y, Isobe M, Oka M and Nakayama E.
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-16K18463
[Presentation] Role of TIM-3/Galectin-9 pathway in lung adenocarcinoma2016
- Author(s)
  Ohue Y, Kurose K, Nishio Y, Isobe M, Oka M and Nakayama E.
- Organizer
  CRI-CIMT-EATI-AACR Second International Cancer Immunotherapy Conference
- Place of Presentation
  ニューヨーク（アメリカ）
- Data Source
  KAKENHI-PROJECT-16K18463
[Presentation] 肺腺癌のTIM-3/Galectin-9経路を介した免疫抑制と予後2016
- Author(s)
  黒瀬浩史
- Organizer
  第57回日本肺癌学会学術集会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Data Source
  KAKENHI-PROJECT-16K21533

1. Oka Mikio (40223995)

# of Collaborated Projects: 4 results

# of Collaborated Products: 18 results
2. Ohue Yoshihiro (70435014)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
3. Nakayama Eiichi (60180428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results

Kurose Koji 黒瀬 浩史

Research Projects

Research Products

Co-Researchers

肺腺がん特異的に発現するXAGE1抗原を標的にした診断薬と治療法の特許開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肺がん免疫療法の効果をモニタリングする血清マーカーの特許開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肺がん免疫療法の効果を予測する多抗原性血清抗体検出パネルの臨床開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Tumor immune microenvironment reviving chemotherapy sensitivity in lung cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of tumor microenvironment involving tumor infiltrating regulatory T cells in lung cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of immunosuppressive factor in tumor microenvironment in patient with lung cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Immune checkpoint therapy and response biomarkers in non-small-cell lung cancer: Serum NY-ESO-1 and XAGE1 antibody as predictive and monitoring markers2023

Author(s)

Journal Title

DOI

ISBN

Data Source

[Journal Article] A novel automated immunoassay for serum NY-ESO-1 and XAGE1 antibodies in combinatory prediction of response to anti-programmed cell death-1 therapy in non-small-cell lung cancer2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Serum Antibody Against NY-ESO-1 and XAGE1 Antigens Potentially Predicts Clinical Responses to Anti?Programmed Cell Death-1 Therapy in NSCLC2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] NY-ESO-1 Protein Cancer Vaccine With Poly-ICLC and OK-432: Rapid and Strong Induction of NY-ESO-1-specific Immune Responses by Poly-ICLC2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nivolumab-induced polyarthritis.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Survival of Lung Adenocarcinoma Patients Predicted from Expression of PD-L1, Galectin-9, and XAGE1 (GAGED2a) on Tumor Cells and Tumor-Infiltrating T Cells.2016

Author(s)

Journal Title

Data Source

[Journal Article] Survival of Lung Adenocarcinoma Patients Predicted from Expression of PD-L1, Galectin-9, and XAGE1 (GAGED2a) on Tumor Cells and Tumor-Infiltrating T Cells2016

Author(s)

Journal Title

Data Source

[Presentation] 非小細胞肺がんの周術期におけるがん免疫応答の解析 周術期免疫チェックポイント療法の血清バイオマーカー開発へ向けて2023

Author(s)

Organizer

Data Source

[Presentation] 肺がん免疫チェックポイント療法の効果を予測する血清バイオマーカーの全自動測定法の開発2023

Kurose Koji 黒瀬浩史

[Presentation] 非小細胞肺がんの周術期におけるがん免疫応答の解析　周術期免疫チェックポイント療法の血清バイオマーカー開発へ向けて2023