YOTSUMOTO Junko 四元淳子

Researcher Number	30553648
Other IDs
Affiliation (based on the past Project Information) *help	2021 – 2022: 昭和大学, 医学部, 特別研究生 2018 – 2021: 国際医療福祉大学, 大学院, 講師 2020: 昭和大学, 医学部, その他 2011 – 2019: 昭和大学, 医学部, 特別研究生 2017: お茶の水女子大学, 基幹研究院, 助教
Review Section/Research Field	Principal Investigator Obstetrics and gynecology Except Principal Investigator Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related / Basic Section 58010:Medical management and medical sociology-related / Embryonic/Neonatal medicine
Keywords	Principal Investigator ゲノム / 遺伝子 / vanishing twin / ヘパリン投与 / 疑陽性 / 胎児DNA / 胎盤性モザイク / 母体疾患 / 偽陽性 / 判定保留 … More / genetic counseling / discordant result / cell free DNA / NIPT … More Except Principal Investigator 妊娠高血圧症候群 / 絨毛細胞 / 妊娠初期絨毛 / 遺伝カウンセリング / DNAメチル化 / 初期絨毛 / 胎盤形成期 / 妊娠高血圧腎症 / 胎盤 / 再発 / 子宮内細菌叢 / 子宮内フローラ / 慢性子宮内感染 / 常位胎盤早期剥離 / 教育評価 / シミュレーション教育 / ロールプレイ / ルーブリック / 模擬面接 / 絨毛検査 / 妊娠高血圧症侯群 / 絨毛 / 次世代シークエンサー / エクソーム解析 / 胎児異常 / 中枢神経異常 / 遺伝子診断 / 骨系統疾患 / 絨毛細胞分化 / エピジェネティクス / 喫煙 / 妊娠絨毛 / 妊娠初期 / 胎盤形成 / miRNA / エンドグリン / 抗酸化剤 / 母体血RNA / FLT-1 / 抗血管増殖因子 / 母体血漿RNA / 血管増殖因子 / 非侵襲的出生前遺伝子診断 / 無侵襲的出生前診断 / 無侵襲 / 出生前診断 / 有核赤血球 Less

Study on the mechanism of placental abruption from the viewpoint of uterine microbiota
- Principal Investigator
  
  Sekizawa Akihiko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Showa University
Creation of genetic counseling role-play curriculum with rubric table
- Principal Investigator
  
  MIYAKE Hidehiko
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58010:Medical management and medical sociology-related
- Research Institution
  Ochanomizu University
Study on the elucidation of the discordant result of NIPT and its clinical significance by MPS methodPrincipal Investigator
- Principal Investigator
  
  Yotsumoto Junko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  International University of Health and Welfare
  Ochanomizu University
Pathophysiology of hypertensive disorder of pregnancy through DNA methylation analysis of villous trophoblasts in first trimester
- Principal Investigator
  
  Sekizawa Akihiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Showa University
Cause elucidation of the severe fetal disease by the next-generation sequencer and establishment of the gene library
- Principal Investigator
  
  Matsuoka Ryu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Showa University
The alterations of villous DNA methylation in first trimester associated with the pathogenesis of preeclampsia
- Principal Investigator
  
  Sekizawa Akihiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Showa University
Preeclampsia and placenta-specific microRNA
- Principal Investigator
  
  SAITO HIROSHI
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Showa University
Development of noninvasive prenatal diagnosis using nucleated erythrocyte in maternal blood
- Principal Investigator
  
  MATSUOKA Ryu
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Showa University
Prediction and prevention of preeclampsia
- Principal Investigator
  
  SEKIZAWA Akihiko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Showa University

All 2020 2019 2018 2016 2015 2014 2013 2012 2011

All Journal Article Presentation Book

[Book] 周産期遺伝カウンセリングマニュアル　改訂3版2020
- Author(s)
  関沢明彦，佐村修，四元淳子
- Total Pages
  216
- Publisher
  中外医学社
- ISBN
  9784498160064
- Data Source
  KAKENHI-PROJECT-17K11219
[Journal Article] Qualitative investigation of the factors that generate ambivalent feelings in women who give birth after receiving negative results from non-invasive prenatal testing2020
- Author(s)
  Yotsumoto J, Sekizawa A, Inoue S, Suzumori N, Samura O, Yamada T, Miura K, Masuzaki H, Sawai H, Murotsuki J, Hamanoue H, Kamei Y, Endo T, Fukushima A, Katagiri Y, Takeshita N, Ogawa M, Nishizawa H, Okamoto Y, Tairaku S, Kaji T, Maeda K, Matsubara K, Ogawa M, Osada H, Ohba T, Kawano Y, Sasaki A, Sago H
- Journal Title
  
  BMC Pregnancy and Childbirth
  
  Volume: 20 Issue: 1 Pages: 112-112
- DOI
  10.1186/s12884-020-2763-z
- NAID
  120007174409
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08305, KAKENHI-PROJECT-17K11219
[Journal Article] Classification of factors involved in nonreportable results of noninvasive prenatal testing (NIPT) and prediction of success rate of second NIPT2019
- Author(s)
  Suzumori N, Sekizawa A, Samura O, Yotsumoto J, Sago H,et al
- Journal Title
  
  Prenatal Diagnosis
  
  Volume: 39(2) Issue: 2 Pages: 100-106
- DOI
  10.1002/pd.5408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11219, KAKENHI-PROJECT-17K11283, KAKENHI-PROJECT-15H03283, KAKENHI-PROJECT-16K11088, KAKENHI-PROJECT-17K11241
[Journal Article] Fetal cell-free DNA fraction in maternal plasma for the prediction of hypertensive disorders of pregnancy2018
- Author(s)
  Suzumori , Sekizawa A,Yotsumoto J, et al
- Journal Title
  
  Eur J Obstet Gynecol Reprod Biol
  
  Volume: 224 Pages: 165-169
- DOI
  10.1016/j.ejogrb.2018.03.048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11219, KAKENHI-PROJECT-17K11241, KAKENHI-PROJECT-17K11252, KAKENHI-PROJECT-17K11283, KAKENHI-PROJECT-16K10106, KAKENHI-PROJECT-16K11088
[Journal Article] Maternal Smoking and Placental Expression of a Panel of Genes Related to Angiogenesis and Oxidative Stress in Early Pregnancy2014
- Author(s)
  Shinjo A, Ventura W, Koide K, Hori K, Yotsumoto J, Matsuoka R, Ichizuka K, Sekizawa A
- Journal Title
  
  Fetal Diagn Ther
  
  Volume: (PMID:24642658)
- Data Source
  KAKENHI-PROJECT-23592417
[Journal Article] Maternal Smoking and Placental Expression of a Panel of Genes Related to Angiogenesis and Oxidative Stress in Early Pregnancy.2014
- Author(s)
  Shinjo A, Ventura W, Koide K, Hori K, Yotsumoto J, Matsuoka R, Ichizuka K, Sekizawa A.
- Journal Title
  
  Fetal Diagn Ther
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592417
[Journal Article] Placental expression of microRNA-17 and -19b is down-regulated in early pregnancy loss2013
- Author(s)
  Ventura W, Koide K, Hori K, Yotsumoto J, Sekizawa A, Saito H, Okai T.
- Journal Title
  
  Eur J Obstet Gynecol Reprod Biol. 2013 Jul;169(1):28-32
  
  Volume: 169 Issue: 1 Pages: 28-32
- DOI
  10.1016/j.ejogrb.2013.01.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659737
[Journal Article] Physiological Changes in the Pattern of Placental Gene Expression Early in the First Trimester2013
- Author(s)
  Miyagami S, Koide K, Sekizawa A, Ventura W, Yotsumoto J, Oishi S, Okai T.
- Journal Title
  
  Reprod Sci
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592417
[Journal Article] 無侵襲的出生前遺伝学的検査（non invasive prenatal genetic testing;NIPT）に関するフォーカス・グループインタビュー2013
- Author(s)
  四元淳子、宮上景子、白土なほ子、市塚清健、関沢明彦
- Journal Title
  
  産婦人科の実際
  
  Volume: 62 Pages: 1421-1426
- Data Source
  KAKENHI-PROJECT-23591602
[Journal Article] Physiological changes in the pattern of placental gene expression early in the first trimester2012
- Author(s)
  Miyagami S, Koide K, Sekizawa A, Ventura W, Yotsumoto J, Oishi S, Okai T.
- Journal Title
  
  Reproductive Sciences
  
  Volume: 20(6) Pages: 710-714
- Data Source
  KAKENHI-PROJECT-23592417
[Journal Article] Attitudes toward non-invasive prenatal diagnosis among pregnant women and health professionals in Japan2012
- Author(s)
  Junko Yotsumoto, Akihiko Sekizawa, Keiko Koide, Yuditiya Purwosunu, Kiyotake Ichizuka, Ryu Matsuoka, Hiroshi Kawame, Takashi Okai
- Journal Title
  
  Prenatal Diagnosis
  
  Volume: 32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591602
[Journal Article] Attitudes toward non-invasive prenatal diagnosis among pregnant women and health professionals in Japan2012
- Author(s)
  Yotsumoto J, Sekizawa A, Koide K, Purwosunu Y, Ichizuka K, Matsuoka R, Kawame H, Okai T
- Journal Title
  
  Prenat Diagn
  
  Volume: 32(7) Pages: 674-9
- Data Source
  KAKENHI-PROJECT-23591602
[Journal Article] Attitudes toward non-invasive prenatal diagnosis among pregnant women and health professionals in Japan.2012
- Author(s)
  Yotsumoto J, Sekizawa A, Koide K, Purwosunu Y, Ichizuka K, Matsuoka R, Kawame H, Okai T.
- Journal Title
  
  Prenat Diagn
  
  Volume: 32 Issue: 7 Pages: 674-9
- DOI
  10.1002/pd.3886
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591602
[Journal Article] Role of epigenetics in the placenta : Alterations in DNA promoter methylation and imprinted genes2011
- Author(s)
  Koide K, Sekizawa A, Yotsumoto J, Miyagami S, Ichizuka K, Matsuoka R, Okai T.
- Journal Title
  
  J Mamm Ova Res
  
  Volume: 28 Pages: 103-109
- Data Source
  KAKENHI-PROJECT-23592417
[Journal Article] 母体血からの胎児遺伝子診断2011
- Author(s)
  関沢明彦、四元淳子、松岡隆、岡井崇、高林晴夫、北川道弘
- Journal Title
  
  周産期医学
  
  Volume: 41 Pages: 100-104
- Data Source
  KAKENHI-PROJECT-23591602
[Journal Article] Role of epigenetics in the placenta: Alterations in DNA promoter methylation and imprinted genes.2011
- Author(s)
  Koide K, Sekizawa A, Yotsumoto J, Miyagami S, Ichizuka K, Matsuoka R, Okai T.
- Journal Title
  
  J Mamm Ova Res
  
  Volume: 28 Pages: 103-109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592417
[Presentation] 標準化を目指した遺伝カウンセリングロールプレイ事例の解析2019
- Author(s)
  三宅秀彦四元淳子浦野真理櫻井晃洋蒔田芳男
- Organizer
  第５１回日本医学教育学会大会
- Data Source
  KAKENHI-PROJECT-18K09997
[Presentation] A survey on the ambivalence among women who gave birth after receiving a negative result on non-invasive prenatal genetic testing .ISPD 2019 Sep, Singapore2019
- Author(s)
  Junko Yotsumoto
- Organizer
  ISPD annual meeting 2019(International Conference on Prenatal Diagnosis and Therapy)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11219
[Presentation] 出生前検査の遺伝カウンセリングにおける基本的態度と家族歴聴取2018
- Author(s)
  四元淳子
- Organizer
  第4回　日本産科婦人科遺伝子診療学会学術講演会　(東京)
- Invited
- Data Source
  KAKENHI-PROJECT-17K11219
[Presentation] 産婦人科領域における遺伝カウンセリング2018
- Author(s)
  四元淳子
- Organizer
  第70回日本産婦人科学会学術講演会（仙台国際センター）
- Invited
- Data Source
  KAKENHI-PROJECT-17K11219
[Presentation] 遺伝性乳がん卵巣がんとNIPTの遺伝カウンセリング2018
- Author(s)
  四元淳子
- Organizer
  第59回母性衛生学会（新潟）
- Invited
- Data Source
  KAKENHI-PROJECT-17K11219
[Presentation] Effect of the mental background factor of after childbirth women who done prenatal testings2016
- Author(s)
  Nahoko Shirato, Miwa Sakamoto, Keiko Miyagami, Junko Yotsumoto, Atshko Saito, Tatuko Hirose, Mikiko Izumi, Ryu Matsuoka, Kiyotake Ichizuka, Akihiko Sekizawa
- Organizer
  13th International Congress of Human Genetics
- Place of Presentation
  京都
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10690
[Presentation] Mental background of pregnant women in the viewpoint of delivering facilities2016
- Author(s)
  Keiko MIYAGAMI, Nahoko SHIRATO, Miwa SAKAMOTO, Junko YOTSUMOTO, Atsuko SAITO, Tatsuko HIROSE, Mikiko IZUMI, Ryu MATUOKA, Kiyotake ICHIZUKA, Akihiko SEKIZAWA
- Organizer
  13th International Congress of Human Genetics
- Place of Presentation
  京都
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10690
[Presentation] 産婦人科医が関わる遺伝カウンセリングの現状と今後の課題出生前遺伝学的検査の現状と課題2015
- Author(s)
  関沢明彦, 松岡隆, 四元淳子, 白土なほ子
- Organizer
  日本遺伝カウンセリング学会
- Place of Presentation
  千葉
- Year and Date
  2015-06-25
- Data Source
  KAKENHI-PROJECT-15K10690
[Presentation] 無侵襲的出生前診断の臨床応用に向けた問題点について2012
- Author(s)
  四元淳子、関沢明彦、小出馨子、市塚清健、松岡隆、岡井崇
- Organizer
  第15回胎児遺伝子診断研究会
- Place of Presentation
  東京
- Year and Date
  2012-02-04
- Data Source
  KAKENHI-PROJECT-23591602
[Presentation] 妊娠高血圧症候群と胎盤のDNA methylationに関する研究2012
- Author(s)
  小出馨子,関沢明彦,宮上哲,四元淳子,仲村将光,大石親護,岡井崇
- Organizer
  第64回日本産科婦人科学会学術講演会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23592417
[Presentation] Attitude toward NIPT in Japan2012
- Author(s)
  Yotsumoto J, Sekizawa A, Okai T
- Organizer
  FDD-MB WWRC 2012 (Fetal DND Diagnosis from Maternal Blood Worldwide Researchers Conference 2012)
- Place of Presentation
  KANAZAWA
- Year and Date
  2012-11-24
- Data Source
  KAKENHI-PROJECT-23591602
[Presentation] 無侵襲的出生前遺伝学的検査・診断に関する意識調査2011
- Author(s)
  四元淳子、関沢明彦、小出馨子、長船奈津美、堀尾留里子、廣瀬達子、犬塚真由子、松岡隆、市塚清健、岡井崇
- Organizer
  第56回日本人類遺伝学会
- Place of Presentation
  千葉
- Year and Date
  2011-11-10
- Data Source
  KAKENHI-PROJECT-23591602
[Presentation] 札幌胎盤形成期における絨毛のDNA methylationに関する研究2011
- Author(s)
  小出馨子、関沢明彦、宮上哲、仲村将光、四元淳子、岡井崇
- Organizer
  第47回日本周産期・新生児医学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23592417
[Presentation] Non-invasive prenatal determination of fetal gender and single-gene disorder from plasma of pregnant women2011
- Author(s)
  Yotsumoto J, Sekizawa A, Fukuda A, et al
- Organizer
  22^<nd> Asian and Oceanic Congress of Obsterics and Gynecology
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2011-09-25
- Data Source
  KAKENHI-PROJECT-23591602
[Presentation] 妊娠初期絨毛における遺伝子発現量の妊娠週数に伴う変化2011
- Author(s)
  宮上哲、関沢明彦、小出馨子、仲村将光、四元淳子、岡井崇
- Organizer
  第47回日本周産期・新生児医学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23592417

1. SEKIZAWA Akihiko (10245839)

# of Collaborated Projects: 8 results

# of Collaborated Products: 25 results
2. MATSUOKA Ryu (20349111)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
3. 小出馨子 (90384437)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 川嶋章弘 (10783376)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. SAITO HIROSHI (30119193)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. MIYAKE Hidehiko (40297932)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 蒔田芳男 (20271778)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 浦野真理 (20752752)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 櫻井晃洋 (70262706)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. Takenaka Shin

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 亀井良政

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YOTSUMOTO Junko 四元 淳子

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[Book] 周産期遺伝カウンセリングマニュアル 改訂3版2020

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[Journal Article] Qualitative investigation of the factors that generate ambivalent feelings in women who give birth after receiving negative results from non-invasive prenatal testing2020

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[Journal Article] Classification of factors involved in nonreportable results of noninvasive prenatal testing (NIPT) and prediction of success rate of second NIPT2019

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[Journal Article] Fetal cell-free DNA fraction in maternal plasma for the prediction of hypertensive disorders of pregnancy2018

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[Journal Article] Maternal Smoking and Placental Expression of a Panel of Genes Related to Angiogenesis and Oxidative Stress in Early Pregnancy2014

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[Journal Article] Maternal Smoking and Placental Expression of a Panel of Genes Related to Angiogenesis and Oxidative Stress in Early Pregnancy.2014

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YOTSUMOTO Junko 四元淳子

[Book] 周産期遺伝カウンセリングマニュアル　改訂3版2020

[Presentation] 出生前検査の遺伝カウンセリングにおける基本的態度と家族歴聴取2018