TANAKA KENICHIRO 田中健一郎

… Alternative Names

Tanaka Ken-ichiro 田中健一郎

TANAKA Kenichiro 田中健一郎

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Researcher Number	30555777
Other IDs
Affiliation (Current)	2025: 武蔵野大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2025: 武蔵野大学, 薬学部, 准教授 2018 – 2024: 武蔵野大学, 薬学部, 講師 2016: 武蔵野大学, 薬学研究所, 講師 2013 – 2015: 慶應義塾大学, 薬学部, 助教 2012: 熊本大学, 生命科学研究部(薬), 助教 2010 – 2011: 熊本大学, 大学院・生命科学研究部, 助教
Review Section/Research Field	Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Biological pharmacy / Basic Section 47040:Pharmacology-related / Pharmacology in pharmacy Except Principal Investigator Basic Section 47060:Clinical pharmacy-related / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
Keywords	Principal Investigator 既存薬 / スクリーニング / 肺線維症 / ストレスタンパク質 / 予防法 / 肺傷害 / 酸化ストレス / PM2.5 / 大気汚染 / メタロチオネイン … More / ドラッグリポジショニング / ライブラリー / 細胞死 / 肺線維芽細胞 / 呼吸器 / IPF / 線維化 / 線維芽細胞 / 線維症 / 特発性肺線維症 / 肺線維化 / ストレス / 呼吸器疾患 / 消化管 … More Except Principal Investigator 大規模副作用データベース / 金属 / アルツハイマー病 / HPLC / アミロイド / チャネル / 微量元素 / アポトーシス / カルシウム / 神経毒性 / カルノシン / プリオン / プリオン病 / 過酸化 / 神経細胞死 / シナプス / コンフォメーション / 銅 / 亜鉛 / カルシウムホメオスタシス / 酸化ストレス / 小胞体ストレス Less

大気汚染物質の長期曝露に起因する呼吸器疾患に対するメタロチオネインの機能解析Principal Investigator
- Principal Investigator
  
  田中健一郎
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Musashino University
大規模医療情報とオミクスデータを活用した新たな薬剤性間質性肺疾患予防薬の開発
- Principal Investigator
  
  名和秀起
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Okayama University
Analysis of the protective effect of metallothioneins against lung injury caused by air pollutants.Principal Investigator
- Principal Investigator
  
  田中健一郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Musashino University
Effects of metals on oligomerization, channel formation, and neurotoxicity of amyloidogenic proteins
- Principal Investigator
  
  Kawahara Masahiro
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Musashino University
Elucidation of the molecular mechanism of preferential suppression of fibroblast activity and its application to the treatment of pulmonary fibrosisPrincipal Investigator
- Principal Investigator
  
  Tanaka Ken-ichiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Musashino University
Elucidation of the mechanism of suppressing pulmonary fibrosis by stress proteins and its application to IPF therapyPrincipal Investigator
- Principal Investigator
  
  Tanaka Ken-ichiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Musashino University
  Keio University
Regulation of inflammation by stress proteinsPrincipal Investigator
- Principal Investigator
  
  TANAKA Kenichiro
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Keio University
  Kumamoto University
The role of stress proteins in gastrointestinal and respiratory diseasesPrincipal Investigator
- Principal Investigator
  
  TANAKA Kenichiro
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kumamoto University

[Journal Article] Ergothioneine Prevents Neuronal Cell Death Caused by the Neurotoxin 6-Hydroxydopamine2024
- Author(s)
  Yuzawa Saho、Nakashio Motonari、Ichimura Suzuna、Shimoda Mikako、Nakashima Ayaka、Marukawa-Hashimoto Yuka、Kawano Yusuke、Suzuki Kengo、Yoshitomi Kenichi、Kawahara Masahiro、Tanaka Ken-ichiro
- Journal Title
  
  Cells
  
  Volume: 13 Issue: 3 Pages: 230-230
- DOI
  10.3390/cells13030230
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06588
[Journal Article] Exacerbation of Elastase-Induced Emphysema via Increased Oxidative Stress in Metallothionein-Knockout Mice2022
- Author(s)
  Tanaka KI, Shiota S, Sakakibara O, Shimoda M, Takafuji A, Takabatake M, Kadota Y, Kawakami T, Suzuki S, Kawahara M.
- Journal Title
  
  Biomolecules
  
  Volume: 12(4) Issue: 4 Pages: 583-583
- DOI
  10.3390/biom12040583
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06588
[Journal Article] Neurotoxicity of Aluminum and its link with neurodegenerative diseases.2022
- Author(s)
  Kawahara Masahiro, Tanaka Ken-ichiro, Kato-Negishi Midori
- Journal Title
  
  Metallomics Research
  
  Volume: 1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06669
[Journal Article] 神経疾患発症におけるアミロイド形成タンパク質とニューロメタルのクロストーク2022
- Author(s)
  川原正博、田中健一郎、根岸みどり
- Journal Title
  
  月刊「細胞」
  
  Volume: 54 Pages: 35-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06669
[Journal Article] Effects of selenium-containing compounds on Cu<sup>2+</sup>/Zn<sup>2+</sup>-induced neuronal cell death and potential application as therapeutic agents for neurological diseases2022
- Author(s)
  Tanaka Ken-ichiro、Shimoda Mikako、Kawahara Masahiro
- Journal Title
  
  Neural Regeneration Research
  
  Volume: 17 Issue: 2 Pages: 311-311
- DOI
  10.4103/1673-5374.317968
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06669
[Journal Article] Preventive Effect of Epigallocatechin Gallate, the Main Component of Green Tea, on Acute Lung Injury Caused by Air Pollutants2022
- Author(s)
  Tanaka KI, Nakaguchi S, Shiota S, Nakada Y, Oyama K, Sakakibara O, Shimoda M, Sugimoto A, Ichitani M, Takihara T, Kinugasa H, Kawahara M.
- Journal Title
  
  Biomolecules
  
  Volume: 12(9) Issue: 9 Pages: 1196-1196
- DOI
  10.3390/biom12091196
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06588
[Journal Article] 微量金属元素のホメオスタシス崩壊が導く神経細胞死の誘導機構解明2021
- Author(s)
  田中健一郎
- Journal Title
  
  Biomedical Research on Trace Elements
  
  Volume: 32 Pages: 16-23
- NAID
  130008049962
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06669
[Journal Article] Copper as a Collaborative Partner of Zinc-Induced Neurotoxicity in the Pathogenesis of Vascular Dementia2021
- Author(s)
  Kawahara Masahiro、Tanaka Ken-ichiro、Kato-Negishi Midori
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 14 Pages: 7242-7242
- DOI
  10.3390/ijms22147242
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06669, KAKENHI-PROJECT-17H03197
[Journal Article] Neurometals in the Pathogenesis of Prion Diseases2021
- Author(s)
  Kawahara Masahiro、Kato-Negishi Midori、Tanaka Ken-ichiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 3 Pages: 1267-1267
- DOI
  10.3390/ijms22031267
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06669
[Journal Article] Thioredoxin-albumin fusion protein prevents urban aerosol-induced lung injury via suppressing oxidative stress-related neutrophil extracellular trap formation.2021
- Author(s)
  Tanaka KI, Kubota M, Shimoda M, Hayase T, Miyaguchi M, Kobayashi N, Ikeda M, Ishima Y, Kawahara M.
- Journal Title
  
  Environ Pollut.
  
  Volume: 268(Pt A) Pages: 115787-115787
- DOI
  10.1016/j.envpol.2020.115787
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06691, KAKENHI-PROJECT-18K06669
[Journal Article] 微量金属元素のホメオスタシス崩壊が導く神経細胞死の誘導機構解明2021
- Author(s)
  田中健一郎
- Journal Title
  
  薬学研究の進歩
  
  Volume: 37 Pages: 49-54
- NAID
  130008049962
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06669
[Journal Article] Carnosine as a Possible Drug for Zinc-Induced Neurotoxicity and Vascular Dementia.2020
- Author(s)
  Kawahara M, Sadakane Y, Mizuno K, Kato-Negishi M, Tanaka KI.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 21 Issue: 7 Pages: 2570-2570
- DOI
  10.3390/ijms21072570
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06669, KAKENHI-PROJECT-19K07031, KAKENHI-PROJECT-17H03197
[Journal Article] Carnosine suppresses neuronal cell death and inflammation induced by 6-hydroxydopamine in an in vitro model of Parkinson's disease.2020
- Author(s)
  Kubota M, Kobayashi N, Sugizaki T, Shimoda M, Kawahara M, Tanaka KI.
- Journal Title
  
  PLoS One
  
  Volume: 1 Issue: 10 Pages: e0240448-e0240448
- DOI
  10.1371/journal.pone.0240448
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06669
[Journal Article] Carnosine and Lung Disease2020
- Author(s)
  Tanaka KI, Kawahara M.
- Journal Title
  
  Curr Med Chem
  
  Volume: 27 Issue: 11 Pages: 1714-1725
- DOI
  10.2174/0929867326666190712140545
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06669, KAKENHI-PROJECT-18K06691
[Journal Article] Seleno-L-methionine suppresses copper-enhanced zinc-induced neuronal cell death via induction of glutathione peroxidase.2020
- Author(s)
  Nakano Y, Shimoda M, Okudomi S, Kawaraya S, Kawahara M, Tanaka KI.
- Journal Title
  
  Metallomics
  
  Volume: 12 Issue: 11 Pages: 1693-1701
- DOI
  10.1039/d0mt00136h
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06669
[Journal Article] Amyloids: Regulators of Metal Homeostasis in the Synapse2020
- Author(s)
  Kawahara M, Kato-Negishi M, Tanaka KI
- Journal Title
  
  Molecules
  
  Volume: 25 Issue: 6 Pages: 1441-1441
- DOI
  10.3390/molecules25061441
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06669, KAKENHI-PROJECT-17H03197
[Journal Article] Idebenone has preventative and therapeutic effects on pulmonary fibrosis via preferential suppression of fibroblast activity2019
- Author(s)
  Tanaka Ken-ichiro、Shimoda Mikako、Takafuji Ayaka、Hino Yuuki、Sugizaki Toshifumi、Kawahara Masahiro
- Journal Title
  
  Proceedings for Annual Meeting of The Japanese Pharmacological Society
  
  Volume: 92 Issue: 0 Pages: 3-P-084
- DOI
  10.1254/jpssuppl.92.0_3-P-084
- NAID
  130007813267
- ISSN
  2435-4953
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06691
[Journal Article] Protective effect of polaprezinc on cadmium-induced injury of lung epithelium.2019
- Author(s)
  Kimura K, Nakano Y, Sugizaki T, Shimoda M, Kobayashi N, Kawahara M, Tanaka KI.
- Journal Title
  
  Metallomics
  
  Volume: 11 Issue: 7 Pages: 1310-1320
- DOI
  10.1039/c9mt00060g
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06669
[Journal Article] Involvement of SAPK/JNK signaling pathway in copper enhanced zinc-induced neuronal cell death.2019
- Author(s)
  Tanaka KI1, Shimoda M1, Kasai M1, Ikeda M2, Ishima Y2, Kawahara M
- Journal Title
  
  Toxicol Sci. 2019 Feb 15. pii: kfz043. doi: 10.1093/toxsci/kfz043. [Epub ahead of print]
  
  Volume: Feb15 Issue: 1 Pages: 043-043
- DOI
  10.1093/toxsci/kfz043
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06669, KAKENHI-PROJECT-18J10935, KAKENHI-PROJECT-18H02587
[Journal Article] 神経系における亜鉛の役割、2019
- Author(s)
  川原正博、田中健一郎、根岸みどり
- Journal Title
  
  ClinicalNeuroscience
  
  Volume: 37 Pages: 333-337
- Data Source
  KAKENHI-PROJECT-18K06669
[Journal Article] Chemical modification-mediated optimisation of bronchodilatory activity of mepenzolate, a muscarinic receptor antagonist with anti-inflammatory activity.2019
- Author(s)
  Yamashita Y, Tanaka KI, Yamakawa N, Asano T, Kanda Y, Takafuji A, Kawahara M, Takenaga M, Fukunishi Y, Mizushima T.
- Journal Title
  
  Chemical modification-mediated optimisation of bronchodilatory activity of mepenzolate, a muscarinic receptor antagonist with anti-inflammatory activity.
  
  Volume: 17 Issue: 15 Pages: 3339-3346
- DOI
  10.1016/j.bmc.2019.06.016
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06669
[Journal Article] Nickel enhances zinc-induced neuronal cell death by priming the endoplasmic reticulum stress response.2019
- Author(s)
  Tanaka KI, Kasai M, Shimoda M, Shimizu A, Kubota M, Kawahara M.
- Journal Title
  
  Oxid Med Cell Longev
  
  Volume: 17 Pages: 9693726-9693726
- DOI
  10.1155/2019/9693726
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06669
[Journal Article] Idebenone has preventative and therapeutic effects on pulmonary fibrosis via preferential suppression of fibroblast activity.2019
- Author(s)
  Sugizaki T, Tanaka KI, Asano T, Kobayashi D, Hino Y, Takafuji A, Shimoda M, Mogushi K, Kawahara M, Mizushima T.
- Journal Title
  
  Cell Death Discov
  
  Volume: 5 Pages: 146-146
- NAID
  130007813267
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06669
[Journal Article] 脳血管性認知症発症における亜鉛と銅のクロストーク2019
- Author(s)
  川原正博、根岸みどり、田中健一郎
- Journal Title
  
  亜鉛栄養治療
  
  Volume: 9 Pages: 56-65
- NAID
  40021925031
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06669
[Journal Article] Pyruvic acid prevents Cu2+/Zn2+-induced neurotoxicity by suppressing mitochondrial injury.2018
- Author(s)
  Tanaka KI, Shimoda M, Kawahara M.
- Journal Title
  
  Biochem Biophys Res Commun. 2018 Jan 1;495(1):1335-1341. doi: 10.1016/j.bbrc.2017.11.152. Epub 2017 Nov 24.
  
  Volume: 495 Issue: 1 Pages: 1335-1341
- DOI
  10.1016/j.bbrc.2017.11.152
- Data Source
  KAKENHI-PROJECT-18K06669
[Journal Article] Zinc, Carnosine, and Neurodegenerative Diseases.2018
- Author(s)
  Kawahara M, Tanaka KI, Kato-Negishi M.
- Journal Title
  
  Nutrients. 2018 Jan 29;10(2). pii: E147. doi: 10.3390/nu10020147.
  
  Volume: 10 Issue: 2 Pages: 1-20
- DOI
  10.3390/nu10020147
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06669
[Journal Article] 亜鉛と神経疾患2018
- Author(s)
  川原正博、根岸みどり、田中健一郎
- Journal Title
  
  ファルマシア、54(7), 663-666 (2018).
  
  Volume: 54 Pages: 663-666
- NAID
  130007386939
- Data Source
  KAKENHI-PROJECT-18K06669
[Journal Article] Protective and therapeutic effect of felodipine against bleomycin-induced pulmonary fibrosis in mice.2017
- Author(s)
  Tanaka K, Niino T, Ishihara T, Sugizaki T, Takafuji A, Takayama T, Kanda Y, Tamura F, Kurotsu S, Kawahara M, Mizushima T.
- Journal Title
  
  Sci Rep.
  
  Volume: -
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460104
[Journal Article] Preventive Effects of Carnosine on Lipopolysaccharide-induced Lung Injury.2017
- Author(s)
  Tanaka K, Sugizaki T, Kanda Y, Tamura F, Niino T, Kawahara M.
- Journal Title
  
  Sci Rep.
  
  Volume: 7 Issue: 1 Pages: 42813-42813
- DOI
  10.1038/srep42813
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460104, KAKENHI-PROJECT-26460177
[Journal Article] Superoxide dismutase overexpression protects against glucocorticoid-induced depressive-like behavioral phenotypes in mice.2016
- Author(s)
  Uchihara Y, Tanaka K, Asano T, Tamura F, Mizushima T.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 469 Issue: 4 Pages: 873-877
- DOI
  10.1016/j.bbrc.2015.12.085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460104
[Journal Article] The exacerbating roles of CCAAT/enhancer-binding protein homologous protein (CHOP) in the development of bleomycin-induced pulmonary fibrosis and the preventive effects of tauroursodeoxycholic acid (TUDCA) against pulmonary fibrosis in mice.2015
- Author(s)
  Tanaka Y, Ishitsuka Y, Hayasaka M, Yamada Y, Miyata K, Endo M, Kondo Y, Moriuchi H, Irikura M, Tanaka K, Mizushima T, Oike Y, Irie T.
- Journal Title
  
  Pharmacol Res.
  
  Volume: 99 Pages: 52-62
- DOI
  10.1016/j.phrs.2015.05.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460104, KAKENHI-PUBLICLY-15H01520, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-25461192, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-26670405
[Journal Article] Superiority of pulmonary administration of mepenzolate bromide over other routes as treatment for chronic obstructive pulmonary disease2014
- Author(s)
  Tanaka, K., Kurotsu, S., Asano, T., Yamakawa, N., Kobayashi D., Yamashita, Y., Yamazaki, H., Ishihara, T., Watanabe, H., Maruyama, T., Suzuki, H. and Mizushima, T
- Journal Title
  
  Sci. Rep
  
  Volume: 28 Pages: 4510-4510
- Data Source
  KAKENHI-PROJECT-24790077
[Journal Article] Ameliorative effect of mepenzolate bromide against pulmonary fibrosis.2014
- Author(s)
  Kurotsu, S., Tanaka, K., Niino, T., Asano, T., Sugizaki, T., Azuma, A., Suzuki, H., Mizushima, T.
- Journal Title
  
  J. Pharmacol. Exp. Ther.
  
  Volume: 350 Issue: 1 Pages: 79-88
- DOI
  10.1124/jpet.114.213009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293178, KAKENHI-PROJECT-26460104, KAKENHI-PROJECT-26670065
[Journal Article] Synthesis and biological comparison of enantiomers of mepenzolate bromide, a muscarinic receptor antagonist with bronchodilatory and anti-inflammatory activities.2014
- Author(s)
  Yamashita, Y., Tanaka, K., Asano, T., Yamakawa, N., Kobayashi D., Ishihara, T., Hanaya, K., Shoji, M., Sugai, T., Wada, M., Mashimo, T., Fukunishi, Y. and Mizushima, T.
- Journal Title
  
  Bioorg. & Medic. Chem.
  
  Volume: 22 Issue: 13 Pages: 3488-3497
- DOI
  10.1016/j.bmc.2014.04.029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460104
[Journal Article] Mepenzolate bromide displays beneficial effects in a mouse model of chronic obstructive pulmonary disease.2013
- Author(s)
  Tanaka, K., Ishihara, T., Sugizaki, T., Kobayashi D., Yamashita, Y., Tahara, K., Yamakawa, N., Iijima, K., Mogushi, K., Tanaka, H., Sato, K., Suzuki, H. and Mizushima, T.
- Journal Title
  
  Nature Communications
  
  Volume: 4 Pages: 2686-2686
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790077
[Journal Article] Comparison of pharmacokinetics between loxoprofen and its derivative with lower ulcerogenic activity, fluoro-loxoprofen2013
- Author(s)
  Yamakawa, N., Suemasu, S., Watanabe, H., Tahara, K., Tanaka, K., Okamoto, Y., Ohtsuka, M., Maruyama, T. and Mizushima, T
- Journal Title
  
  Drug Metab. Pharmacokinet
  
  Volume: 28 Pages: 118-124
- NAID
  130004933526
- Data Source
  KAKENHI-PROJECT-24790077
[Journal Article] Mepenzolate bromide displays beneficial effects in a mouse model of chronic obstructive pulmonary disease2013
- Author(s)
  Tanaka, K., Ishihara, T., Sugizaki, T., Kobayashi D., Yamashita, Y., Tahara, K., Yamakawa, N., Iijima, K., Mogushi, K., Tanaka, H., Sato, K., Suzuki, H. and Mizushima, T
- Journal Title
  
  Nature Communications
  
  Volume: 4 Pages: 2686-2686
- Data Source
  KAKENHI-PROJECT-24790077
[Journal Article] Long-acting human serum albumin-thioredoxin fusion protein suppresses bleomycin-induced pulmonary fibrosis progression.2013
- Author(s)
  Tanaka R, Watanabe H, Kodama A, Chuang VT, Ishima Y, Hamasaki K, Tanaka K, Mizushima T, Otagiri M, Maruyama T.
- Journal Title
  
  J Pharmacol Exp Ther.
  
  Volume: 345 Issue: 2 Pages: 271-283
- DOI
  10.1124/jpet.112.201814
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390142, KAKENHI-PROJECT-23659088, KAKENHI-PROJECT-24390043, KAKENHI-PROJECT-24659037, KAKENHI-PROJECT-24659076, KAKENHI-PROJECT-24790077
[Journal Article] Superiority of PC-SOD to other anti-COPD drugs for elastase-induced emphysema and alteration in lung mechanics and respiratory function in mice2012
- Author(s)
  Tanaka, K., Sato, K., Aoshiba, K., Azuma, A. and Mizushima, T.
- Journal Title
  
  Am. J. Physiol. Lung Cell. Mol. Physiol.
  
  Volume: 302 Issue: 12 Pages: L1250-L1261
- DOI
  10.1152/ajplung.00019.2012
- Data Source
  KAKENHI-PROJECT-24659037, KAKENHI-PROJECT-24790077
[Journal Article] Superiority of PC-SOD to other anti-COPD drugs for elastase-induced emphysema and alteration in lung mechanics and respiratory function in mice.2012
- Author(s)
  Tanaka. K. et al.
- Journal Title
  
  Am. J. Physiol. Lung Cell. Mol. Physiol.
  
  Volume: 302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790077
[Journal Article] Expression of 150-kDa oxygen-regulated protein (QRP150) stimulates bleomycin-induced pulmonary fibrosis and dysfunction in mice2012
- Author(s)
  Tanaka, K., et al.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 425 Issue: 4 Pages: 818-824
- DOI
  10.1016/j.bbrc.2012.07.158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J00614, KAKENHI-PROJECT-24659037, KAKENHI-PROJECT-24790077
[Journal Article] Synthesis and biological evaluation of derivatives of 2-{2-fluoro-4-[(2-oxocyclopentyl)methyl ]phenyl}propanoic acid : Non-steroidal anti-inflammatory drugs with low gastric ulcerogenic activity2012
- Author(s)
  Yamakawa, N., Suemasu, S., Okamoto, Y., Tanaka, K., Ishihara, T., Asano, T., Miyata, k., Ohtsuka, M. and Mizushima, T
- Journal Title
  
  J. Med. Chem
  
  Volume: 55 Pages: 5143-5150
- Data Source
  KAKENHI-PROJECT-24790077
[Journal Article] Identification of a unique nsaid, fluoro-loxoprofen with gastroprotective activity.2012
- Author(s)
  Suemasu S., et al.
- Journal Title
  
  Biochem Pharmacol.
  
  Volume: 84 Issue: 11 Pages: 1470-1481
- DOI
  10.1016/j.bcp.2012.09.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J06922, KAKENHI-PROJECT-22300169, KAKENHI-PROJECT-23390028, KAKENHI-PROJECT-24659037, KAKENHI-PROJECT-24659048, KAKENHI-PROJECT-24659103, KAKENHI-PROJECT-24790077
[Journal Article] Effects of lecithinized superoxide dismutase and/or pirfenidone against bleomycin-induced pulmonary fibrosis2012
- Author(s)
  Tanaka, K., Azuma, A., Miyazaki, Y., Sato, K. and Mizushima, T
- Journal Title
  
  Chest
  
  Volume: 142 Pages: 1011-1019
- Data Source
  KAKENHI-PROJECT-24790077
[Journal Article] Effects of β-(1,3-1,6)-D-glucan on irritable bowel syndrome-related colonic hypersensitivity2012
- Author(s)
  Asano, T., Suzuki, H., et al
- Journal Title
  
  Biochem.Biophys.Res.Com.
  
  Volume: 420(2) Issue: 2 Pages: 444-449
- DOI
  10.1016/j.bbrc.2012.03.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300169, KAKENHI-PROJECT-24659037, KAKENHI-PROJECT-24659103, KAKENHI-PROJECT-24790077
[Journal Article] Protective Effect of-β(1, 3-1, 6)-D-glucan against irritant-induced gastric lesions2011
- Author(s)
  Tanaka, K., Tanaka, Y., Suzuki, T. and Mizushima, T.
- Journal Title
  
  Br. J. Nutr
  
  Volume: 106 Pages: 475-485
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790072
[Journal Article] Therapeutic effect of lecithinized superoxide dismutase on pulmonary emphysema2011
- Author(s)
  Tanaka, K., Tanaka, Y., Miyazaki, Y., Namba, T., Sato, K., Aoshiba, K., Azuma, A. and Mizushima, T.
- Journal Title
  
  J. Pharmacol. Exp. Ther
  
  Volume: 338 Pages: 810-818
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790072
[Journal Article] Stimulation of gastric ulcer healing by heat shock protein 702011
- Author(s)
  Ishihara, T., Suemasu, S., Asano, T., Tanaka, K. and Mizushima, T.
- Journal Title
  
  Biochem. Pharmacol
  
  Volume: 82 Pages: 728-736
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790072
[Journal Article] Therapeutic effect of lecithinized superoxide dismutase on pulmonary emphysema2011
- Author(s)
  Tanaka, K., et al
- Journal Title
  
  J.Pharmacol.Exp.Ther.
  
  Volume: 338 Pages: 810-818
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790072
[Journal Article] Protective Effect of β-(1,3-1,6)-D-glucan against irritant-induced gastric lesions2011
- Author(s)
  Tanaka, K., et al
- Journal Title
  
  Br.J.Nutr.
  
  Volume: 106 Pages: 475-485
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790072
[Journal Article] Heat shock protein 70 protects against bleomycin-induced pulmonary fibrosis in mice2010
- Author(s)
  Tanaka, K., Tanaka, Y., Namba, T., Azuma, A. and Mizushima, T.
- Journal Title
  
  Biochem. Pharmacol
  
  Volume: 80 Pages: 920-931
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790072
[Journal Article] Heat shock protein 70 protects against bleomycin-induced pulmonary fibrosis in mice.2010
- Author(s)
  Tanaka.K., et al.
- Journal Title
  
  Biochem.Pharmacol.
  
  Volume: 80 Pages: 920-931
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790072
[Journal Article] Prevention of ultraviolet B radiation-induced epidermal damage by expression of heat shock protein 702010
- Author(s)
  Matsuda, M., Hoshino, T., Yamashita, Y., Tanaka, K., Maji, D., Sato, K., Adachi, H., Sobue, G., Ihn, H., Funasaka, Y. and Mizushima, T.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 285 Pages: 5848-5858
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790072
[Journal Article] Therapeutic effect of lecithinized superoxide dismutase(PC-SOD) on bleomycin-induced pulmonary fibrosis2010
- Author(s)
  Tanaka, K., Ishihara, T., Azuma, A., Kudoh, S., Ebina, M., Nukiwa, T., Sugiyama, Y., Tasaka, Y., Namba, T., Ishihara, T., Sato, K., Mizushima, Y. and Mizushima, T.
- Journal Title
  
  Am. J. Physiol. Lung Cell. Mol. Physiol
  
  Volume: 298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790072
[Journal Article] Therapeutic effect of lecithinized superoxide dismutase (PC-SOD) on bleomycin-induced pulmonary fibrosis.2010
- Author(s)
  Tanaka.K., et al.
- Journal Title
  
  Ant.J.Physiol.Lung Cell.Mol.Physiol.
  
  Volume: 298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790072
[Journal Article] Synthesis and biological comparison of enantiomers of mepenzolate bromide, a muscarinic receptor antagonist with bronchodilatory and anti-inflammatory activities
- Author(s)
  Yamashita, Y., Tanaka, K., Asano, T., Yamakawa, N., Kobayashi D., Ishihara, T., Hanaya, K., Shoji, M., Sugai, T., Wada, M., Mashimo, T., Fukunishi, Y. and Mizushima T
- Journal Title
  
  Bioorg. & Medic. Chem
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-24790077
[Journal Article] Ameliorative effect of mepenzolate bromide against pulmonary fibrosis
- Author(s)
  Kurotsu, S., Tanaka, K., Niino, T., Sugizaki, T., Azuma, A., Suzuki, H. and Mizushima, T
- Journal Title
  
  J. Pharmacol. Exp. Ther
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-24790077
[Presentation] メタロチオネイン欠損マウスを用いた呼吸器疾患モデルの解析と疾患治療への応用2023
- Author(s)
  2.市村涼奈, 塩田沙智恵, 榊原緒妃菜, 門田佳人, 川上隆茂, 鈴木真也, 下田実可子, 川原正博, 田中健一郎.
- Organizer
  第34回日本微量元素学会学術集会
- Data Source
  KAKENHI-PROJECT-22K06588
[Presentation] SDGs達成を目指した、大気汚染肺傷害に対する新規予防法の探索2023
- Author(s)
  田中健一郎
- Organizer
  第76回日本酸化ストレス学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22K06588
[Presentation] 大気汚染肺傷害に対するカラハリスイカ果汁(WWMJ)の予防効果2023
- Author(s)
  田中健一郎, 中島綾香, 鈴木健吾, 塩田沙智恵, 渡辺真以, 舩山梨音子, 下田実可子, 川原正博.
- Organizer
  第76回日本酸化ストレス学会学術集会
- Data Source
  KAKENHI-PROJECT-22K06588
[Presentation] 大気汚染肺傷害モデルを用いたカラハリスイカ果汁（WWMJ）の新機能解析2023
- Author(s)
  4.舩山梨音子, 中島綾香, 鈴木健吾, 渡辺真以, 塩田沙智恵,下田実可子, 川原正博, 田中健一郎.
- Organizer
  第40回日本微量栄養素学会
- Data Source
  KAKENHI-PROJECT-22K06588
[Presentation] Effect of metallothionein on elastase-induced pulmonary emphysema2022
- Author(s)
  Tanaka KI, Shiota S, Sakakibara O, Shimoda M, Takafuji A, Takabatake M, Kadota Y, Kawakami T, Suzuki S, Kawahara M.
- Organizer
  The 8th International Symposium on Metallomics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06588
[Presentation] 呼吸器疾患領域におけるメタロチオネインの機能解析2022
- Author(s)
  田中健一郎, 下田実可子, 高藤綾香, 高畑南咲, 門田佳人, 川上隆茂, 鈴木真也, 川原正博
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-18K06669
[Presentation] 呼吸器疾患に対するメタロチオネイン(MT)、及び MT誘導剤の有効性解析2022
- Author(s)
  田中健一郎, 榊原緒妃菜, 塩田沙智恵, 下田実可子, 高藤綾香, 高畑南咲, 門田佳人, 川上隆茂, 鈴木真也, 川原正博.
- Organizer
  第24回日本亜鉛栄養治療研究会学術集会
- Data Source
  KAKENHI-PROJECT-22K06588
[Presentation] 6-hydroxydopamineによる神経細胞死・神経炎症に対するカルノシン(βAla-His)の有効性解析, , 2021年11月.2021
- Author(s)
  塩田沙智恵, 榊原緒妃菜, 久保田真帆, 下田実可子, 田中健一郎, 川原正博.
- Organizer
  新アミノ酸分析研究会第11回学術講演会
- Data Source
  KAKENHI-PROJECT-18K06669
[Presentation] 銅によって増強される亜鉛神経細胞死の分子メカニズム2021
- Author(s)
  川原正博、徳永汐凜、田中健一郎
- Organizer
  第32回日本微量元素学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06669
[Presentation] 神経疾患や肺疾患の治療薬開発を目指したメタロミクス研究2020
- Author(s)
  田中健一郎
- Organizer
  第31回日本微量元素学会学術集会　受賞講演
- Invited
- Data Source
  KAKENHI-PROJECT-18K06669
[Presentation] 6-OHDA依存の神経細胞死に影響を与える微量金属の探索2020
- Author(s)
  久保田真帆、鍋嶋友惟子、中野由加里、田中健一郎、川原正博
- Organizer
  日本薬学会第140年会（京都、2020.03.25-28）
- Data Source
  KAKENHI-PROJECT-18K06669
[Presentation] カドミウム依存の肺胞上皮細胞傷害に対するメタロチオネイン誘導剤の保護効果2020
- Author(s)
  田中健一郎, 木村和真, 杉崎俊文, 中野由加里, 下田実可子, 川原正博
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K06669
[Presentation] 胃潰瘍治療薬・ポラプレジンクの新たな薬理作用の発見2020
- Author(s)
  中野由加里、久保田真帆、杉崎俊文、川原正博、田中健一郎
- Organizer
  日本薬学会第140年会（京都、2020.03.25-28）
- Data Source
  KAKENHI-PROJECT-18K06669
[Presentation] 亜鉛と銅の神経毒性に対するセレノメチオニンの効果2020
- Author(s)
  田中健一郎, 下田実可子, 中野由加里, 久保田真帆, 川原正博
- Organizer
  メタルバイオサイエンス研究会
- Data Source
  KAKENHI-PROJECT-18K06669
[Presentation] Seleno-L-methionineによるCu/Zn依存神経細胞死の阻害効果2020
- Author(s)
  下田実可子, 田中健一郎, 中野由加里, 久保田真帆, 川原正博
- Organizer
  第31回日本微量元素学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06669
[Presentation] 食肉中カルノシン類のHPLCによる定量分析2020
- Author(s)
  川原正博、森　美和子、森田晃子、根岸みどり、田中健一郎
- Organizer
  第31回日本微量元素学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06669
[Presentation] Zinc neurotoxicity and the pathogenesis of vascular type dementia: synergistic interactions between copper and zinc2019
- Author(s)
  Kawahara M, Shimoda M, Kubota M, Hiroki M, Tanaka KI
- Organizer
  7th International Symposium on Metallomics (2019.06.30-07.03, Warsaw, Poland)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06669
[Presentation] Mechanisms by which copper promotes zinc-induced neuronal cell death2019
- Author(s)
  Tanaka K, Kawahara M
- Organizer
  ISTERH 2019 conference, (2019.09.22-26, Bali, Indonesia)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06669
[Presentation] 亜鉛による神経細胞死と老年性認知症2019
- Author(s)
  川原正博、田中健一郎：、
- Organizer
  第46回日本毒性学会学術年会シンポジウム“ニューロジンクの動態制御破綻からみた神経変性疾患研究の新展開“（2019.06.26～28、徳島）
- Invited
- Data Source
  KAKENHI-PROJECT-18K06669
[Presentation] ポラプレジンクはメタロチオネイン誘導を介して、カドミウム依存の肺胞上皮細胞傷害を抑制する2019
- Author(s)
  田中健一郎，木村和真，杉崎俊文，中野由加里，下田実可子，川原正博
- Organizer
  メタルバイオサイエンス研究会2019 (2019.10.29-30, 東京理科大、東京
- Data Source
  KAKENHI-PROJECT-18K06669
[Presentation] 線維芽細胞選択的に作用する薬の探索と特発性肺線維症治療薬への応用2019
- Author(s)
  田中健一郎、下田実可子、高藤綾香、日野優生、杉崎俊文、川原正博
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K06691
[Presentation] Therapeutic effect of idebenone on pulmonary fibrosis via preferential suppression of fibroblast activity2019
- Author(s)
  Tanaka K, Shimoda M, Takafuji A, Sugizaki T, Kawahara M.
- Organizer
  CHEST Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06669
[Presentation] 亜鉛(Zn)/銅(Cu)の神経細胞死におけるSAPK/JNK経路の関与2019
- Author(s)
  田中健一郎, 下田実可子, 廣木美香, 久保田真帆, 池田真由美, 異島優, 川原正博
- Organizer
  第46回日本毒性学会学術年会 (2019.06.22-26, 徳島)
- Data Source
  KAKENHI-PROJECT-18K06669
[Presentation] Molecular pathways of zinc-induced neurotoxicity: involvements in the pathogenesis of vascular dementia2019
- Author(s)
  Kawahara M, Shimoda M, Kubota M, Hiroki M, Tanaka KI
- Organizer
  The 6th meeting of International Society of Zinc Biology (ISZB2019), (2019.09.09-13, Kyoto, Japan)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06669
[Presentation] :ポラプレジンク (カルノシン-亜鉛錯体)はカドミウムによる肺胞上皮細胞傷害を抑制する.2019
- Author(s)
  中野由加里、木村和真、下田実可子、田中健一郎、川原正博
- Organizer
  第１８回日本亜鉛栄養治療研究会・学術集会(2019.2.2, 大阪)
- Data Source
  KAKENHI-PROJECT-18K06669
[Presentation] Carnosine as a possible drug for vascular dementia and lung diseases2019
- Author(s)
  Kawahara M, Shimoda M, Kubota M, Hiroki M, Kato-Negishi M, Tanaka KI
- Organizer
  15th International Symposium on Applied Bioinorganic Chemistry (ISABC), (2019.06.2-5, Nara, Japan)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06669
[Presentation] Therapeutic effect of idebenone on pulmonary fibrosis via preferential suppression of fibroblast activity2019
- Author(s)
  Ken-ichiro Tanaka, Mikako Shimoda, Ayaka Takafuji, Yuki hino, Toshifumi Sugizaki, and Masahiro Kawahara
- Organizer
  CHEST Congress 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06691
[Presentation] ニッケルは酸化ストレスを介して亜鉛による神経細胞死を促進する.2018
- Author(s)
  田中健一郎、葛西美里、下田実可子、清水綾音、久保田真帆、川原正博
- Organizer
  第6回メタロミクス研究フォーラム (2018.11.1-2, 東京)
- Data Source
  KAKENHI-PROJECT-18K06669
[Presentation] Preventive effect of Thioredoxin-Albumin Fusion Protein against Copper enhanced Zinc-induced neuronal cell death.2018
- Author(s)
  Shimoda M, Tanaka K, Ishida T, Ishima Y, Kawahara M.
- Organizer
  SRM2018 (2018.6.29-30, 宮城)
- Data Source
  KAKENHI-PROJECT-18K06669
[Presentation] Preventive effect of Thioredoxin-Albumin Fusion Protein against Copper enhanced Zinc-induced Neurotoxicity.2018
- Author(s)
  Shimoda M, Shimizu A, Takafuji A, Ishida T, Ishima Y, Kawahara M, Tanaka K.
- Organizer
  WCP2018 (2018.7.1-6,京都)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06669
[Presentation] 亜鉛/ニッケルの相互作用による神経細胞死の促進とその促進機構の解明.2018
- Author(s)
  田中健一郎、葛西美里、下田実可子、清水綾音、久保田真帆、川原正博
- Organizer
  メタルバイオサイエンス研究会2018(2018.10.11-14, 宮城)
- Data Source
  KAKENHI-PROJECT-18K06669
[Presentation] 急性肺傷害発症後の抗酸化ペプチド・カルノシンの有効性解析2018
- Author(s)
  高藤綾香、木村和真、田中健一郎、川原正博
- Organizer
  第35回日本微量栄養素学会学術集会 (2018.6.9, 京都)
- Data Source
  KAKENHI-PROJECT-18K06669
[Presentation] 金属-金属相互作用による神経細胞死に対するカルノシンの有効性の解析.2018
- Author(s)
  久保田真帆、田中健一郎、下田実可子、葛西美里、清水綾音、川原正博
- Organizer
  新アミノ酸分析研究会第8回学術講演会(2018.12.17, 東京)
- Data Source
  KAKENHI-PROJECT-18K06669
[Presentation] 亜鉛とニッケルの相互作用による神経細胞死の促進.2018
- Author(s)
  下田実可子、葛西美里、清水綾音、川原正博、田中健一郎
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2018（2018.8.25, 福岡）
- Data Source
  KAKENHI-PROJECT-18K06669
[Presentation] LPS急性肺傷害に対する抗酸化ペプチド・カルノシンの予防効果の検討2017
- Author(s)
  神田侑季、川原正博、田中健一郎
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-26460104
[Presentation] PROTECTIVE AND THERAPEUTIC EFFECT OF FELODIPINE AGAINST BLEOMYCIN-INDUCED PULMONARY FIBROSIS IN MICE2016
- Author(s)
  Niino T, Ishihara T, Tanaka K
- Organizer
  アジア太平洋呼吸器学会（APSR2016）
- Place of Presentation
  The Queen Sirikit National Convention Center (Bangkok)
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460104
[Presentation] Drug discovery and development for COPD by drug re-positioning strategy.2016
- Author(s)
  田中健一郎
- Organizer
  第89回日本薬理学会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市西区）
- Year and Date
  2016-03-09
- Invited
- Data Source
  KAKENHI-PROJECT-26460104

1. Kawahara Masahiro (40224828)

# of Collaborated Projects: 1 results

# of Collaborated Products: 45 results
2. 根岸みどり (30300750)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 名和秀起 (40866547)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 石澤啓介 (60398013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 座間味義人 (70550250)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SUZUKI Hidekazu

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. WATANABE Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. MARUYAMA Toru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. ISHIMA Yu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 水島徹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 根岸みどり(加藤みどり)

# of Collaborated Projects: 0 results

# of Collaborated Products: 12 results
12. 小田切優樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TANAKA KENICHIRO 田中 健一郎

Tanaka Ken-ichiro 田中 健一郎

TANAKA Kenichiro 田中 健一郎

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大気汚染物質の長期曝露に起因する呼吸器疾患に対するメタロチオネインの機能解析Principal Investigator

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大規模医療情報とオミクスデータを活用した新たな薬剤性間質性肺疾患予防薬の開発

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Analysis of the protective effect of metallothioneins against lung injury caused by air pollutants.Principal Investigator

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Effects of metals on oligomerization, channel formation, and neurotoxicity of amyloidogenic proteins

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Elucidation of the molecular mechanism of preferential suppression of fibroblast activity and its application to the treatment of pulmonary fibrosisPrincipal Investigator

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Elucidation of the mechanism of suppressing pulmonary fibrosis by stress proteins and its application to IPF therapyPrincipal Investigator

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Regulation of inflammation by stress proteinsPrincipal Investigator

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The role of stress proteins in gastrointestinal and respiratory diseasesPrincipal Investigator

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[Journal Article] Ergothioneine Prevents Neuronal Cell Death Caused by the Neurotoxin 6-Hydroxydopamine2024

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[Journal Article] Exacerbation of Elastase-Induced Emphysema via Increased Oxidative Stress in Metallothionein-Knockout Mice2022

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[Journal Article] Neurotoxicity of Aluminum and its link with neurodegenerative diseases.2022

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[Journal Article] 神経疾患発症におけるアミロイド形成タンパク質とニューロメタルのクロストーク2022

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[Journal Article] Effects of selenium-containing compounds on Cu<sup>2+</sup>/Zn<sup>2+</sup>-induced neuronal cell death and potential application as therapeutic agents for neurological diseases2022

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[Journal Article] Preventive Effect of Epigallocatechin Gallate, the Main Component of Green Tea, on Acute Lung Injury Caused by Air Pollutants2022

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TANAKA KENICHIRO 田中健一郎

Tanaka Ken-ichiro 田中健一郎

TANAKA Kenichiro 田中健一郎