Nanki Kosaku 南木康作

… Alternative Names

南木康作ナンキコウサク

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Researcher Number	30571137
Other IDs
Affiliation (based on the past Project Information) *help	2024: 慶應義塾大学, 医学部(信濃町), 講師 2022: 慶應義塾大学, 医学部(信濃町), 助教 2021: 慶應義塾大学, 医学部(信濃町), 講師 2020: 慶應義塾大学, 医学部(信濃町), 助教 2018: 慶應義塾大学, 医学部(信濃町), 助教 2017: 慶應義塾大学, 医学部(信濃町), 特任助教
Review Section/Research Field	Principal Investigator Basic Section 49030:Experimental pathology-related / Gastroenterology Except Principal Investigator Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator オルガノイド / 胃がん / Wnt / 形質転換 / 胃癌 Except Principal Investigator CRISPR-Cas9 / エピゲノム / オルガノイド / 胃がん

Elucidation of mechanisms underlying gastric cancer development by epigenetic analysis.
- Principal Investigator
  
  Matano Mami
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Keio University
オルガノイド培養を応用した胃正常組織の分子遺伝学的変化の探索Principal Investigator
- Principal Investigator
  
  南木康作
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Keio University
Investigation of the gastric carcinogenesis using gastric tumor organoid library and artifitial cancer organoids.Principal Investigator
- Principal Investigator
  
  Nanki Kosaku
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University

All 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Cell-matrix interface regulates dormancy in human colon cancer stem cells2022
- Author(s)
  Ohta Yuki、Fujii Masayuki、Takahashi Sirirat、Takano Ai、Nanki Kosaku、Matano Mami、Hanyu Hikaru、Saito Megumu、Shimokawa Mariko、Nishikori Shingo、Hatano Yoshiko、Ishii Ryota、Sawada Kazuaki、Machinaga Akihito、Ikeda Wataru、Imamura Takeshi、Sato Toshiro
- Journal Title
  
  Nature
  
  Volume: 608 Issue: 7924 Pages: 784-794
- DOI
  10.1038/s41586-022-05043-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04995, KAKENHI-PROJECT-20H03757, KAKENHI-PROJECT-22KJ2666, KAKENHI-PROJECT-20K08340
[Journal Article] An organoid-based organ-repurposing approach to treat short bowel syndrome2021
- Author(s)
  Sugimoto S, Kobayashi E, Fujii M, Ohta Y, Arai K, Matano M, Ishikawa K, Miyamoto K, Toshimitsu K, Takahashi S, Nanki K, Hakamata Y, Kanai T, Sato T.
- Journal Title
  
  Nature
  
  Volume: 592 Pages: 99-104
- DOI
  10.1038/s41586-021-03247-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06176, KAKENHI-PROJECT-20H03746, KAKENHI-PROJECT-20H03757, KAKENHI-PROJECT-18KK0246, KAKENHI-PROJECT-23K20316
[Journal Article] Predictors of necessity for endoscopic balloon dilatation in patients with Crohn's disease-related small bowel stenosis2021
- Author(s)
  Yukie Hayashi, Kaoru Takabayashi, Naoki Hosoe, Hiroki Kiyohara, Satoshi Kinoshita, Kosaku Nanki, Kayoko Fukuhara, Yohei Mikami, Tomohisa Sujino, Makoto Mutaguchi, Takaaki Kawaguchi, Motohiko Kato, Haruhiko Ogata, Takanori Kanai
- Journal Title
  
  Ann Med.
  
  Volume: 53 Issue: 1 Pages: 2025-2033
- DOI
  10.1080/07853890.2021.1998597
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08402, KAKENHI-PROJECT-20H03665, KAKENHI-PROJECT-21K16010, KAKENHI-PROJECT-23K20316
[Journal Article] Wnt Signaling Shapes the Histologic Variation in Diffuse Gastric Cancer2021
- Author(s)
  Togasaki K, Sugimoto S, Ohta Y, Nanki K, Matano M, Takahashi S, Fujii M, Kanai T, Sato T.
- Journal Title
  
  Gastroenterology
  
  Volume: 160 Issue: 3 Pages: 823-830
- DOI
  10.1053/j.gastro.2020.10.047
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08340, KAKENHI-PROJECT-17H06176, KAKENHI-PROJECT-20H03746, KAKENHI-PROJECT-20H03757, KAKENHI-PROJECT-20J12287, KAKENHI-PROJECT-23K20316
[Journal Article] An Organoid Biobank of Neuroendocrine Neoplasms Enables Genotype-Phenotype Mapping2020
- Author(s)
  Kawasaki K、Toshimitsu K、Matano M、Fujita M、Kudo Atsushi、Kitagawa Y、Kanai T、Nakagawa H、Sato T, et.al.
- Journal Title
  
  Cell
  
  Volume: 183 Issue: 5 Pages: 1420-1435
- DOI
  10.1016/j.cell.2020.10.023
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09041, KAKENHI-PROJECT-20K08340, KAKENHI-PROJECT-17H06176, KAKENHI-PROJECT-18H04049, KAKENHI-PROJECT-20H03533, KAKENHI-PROJECT-20H03746, KAKENHI-PROJECT-20H03757, KAKENHI-PROJECT-18J21346, KAKENHI-PROJECT-20J12287, KAKENHI-PROJECT-23K20316
[Journal Article] Reconstruction of the Human Colon Epithelium In Vivo.2018
- Author(s)
  Sugimoto S, Ohta Y, Fujii M, Matano M, Shimokawa M, Nanki K, Date S, Nishikori S, Nakazato Y, Nakamura T, Kanai T, Sato T.
- Journal Title
  
  Cell Stem Cell.
  
  Volume: 22 Issue: 2 Pages: 171-176
- DOI
  10.1016/j.stem.2017.11.012
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09325, KAKENHI-PROJECT-17K19674, KAKENHI-PROJECT-17K15967, KAKENHI-ORGANIZER-26115001, KAKENHI-PLANNED-26115007, KAKENHI-PROJECT-15H02534, KAKENHI-PROJECT-15J00981, KAKENHI-PROJECT-16J06433, KAKENHI-PROJECT-17J04827
[Journal Article] Divergent Routes toward Wnt and R-spondin Niche Independency during Human Gastric Carcinogenesis2018
- Author(s)
  Nanki Kosaku、Toshimitsu Kohta、Takano Ai、Fujii Masayuki、Takahashi Sirirat、Sukawa Yasutaka、Ishida Hiroki、Sugimoto Shinya、Kawakubo Hirofumi、Kim Jihoon、Kitagawa Yuko、Sekine Shigeki、Koo Bon-Kyoung、Kanai Takanori、Sato Toshiro
- Journal Title
  
  Cell
  
  Volume: 174 Issue: 4 Pages: 856-869
- DOI
  10.1016/j.cell.2018.07.027
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09395, KAKENHI-ORGANIZER-26115001, KAKENHI-PLANNED-26115007, KAKENHI-PROJECT-17H06176, KAKENHI-PROJECT-16J06433, KAKENHI-PROJECT-17J04827, KAKENHI-PROJECT-18J21346, KAKENHI-PROJECT-16K09325, KAKENHI-PROJECT-17K15967, KAKENHI-INTERNATIONAL-15K21751
[Journal Article] Human Pancreatic Tumor Organoids Reveal Loss of Stem Cell Niche Factor Dependence during Disease Progression.2018
- Author(s)
  Seino T, Kawasaki S, Shimokawa M, Tamagawa H, Toshimitsu K, Fujii M, Ohta Y, Matano M, Nanki K, Kawasaki K, Takahashi S, Sugimoto S, Iwasaki E, Takagi J, Itoi T, Kitago M, Kitagawa Y, Kanai T, Sato T.
- Journal Title
  
  Cell Stem Cell.
  
  Volume: 22 Issue: 3 Pages: 454-467
- DOI
  10.1016/j.stem.2017.12.009
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09325, KAKENHI-PROJECT-17K15967, KAKENHI-PROJECT-17H06176, KAKENHI-PROJECT-15J00981, KAKENHI-PROJECT-16J04984, KAKENHI-PROJECT-16J06433, KAKENHI-PROJECT-17J04827, KAKENHI-PROJECT-17H01420, KAKENHI-ORGANIZER-26115001, KAKENHI-PROJECT-17K19612, KAKENHI-INTERNATIONAL-15K21751
[Presentation] オルガノイドによる胃がんニッチ非依存性獲得機構の解明2019
- Author(s)
  南木康作、佐藤俊朗、金井隆典
- Organizer
  第105回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-17K15967

1. Matano Mami (20439889)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. 佐藤俊朗 (70365245)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
3. TAKANO Ai

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 工藤篤

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 筋野智久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 細江直樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nanki Kosaku 南木 康作

南木 康作 ナンキ コウサク

Research Projects

Research Products

Co-Researchers

Elucidation of mechanisms underlying gastric cancer development by epigenetic analysis.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

オルガノイド培養を応用した胃正常組織の分子遺伝学的変化の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of the gastric carcinogenesis using gastric tumor organoid library and artifitial cancer organoids.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Cell-matrix interface regulates dormancy in human colon cancer stem cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] An organoid-based organ-repurposing approach to treat short bowel syndrome2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Predictors of necessity for endoscopic balloon dilatation in patients with Crohn's disease-related small bowel stenosis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Wnt Signaling Shapes the Histologic Variation in Diffuse Gastric Cancer2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] An Organoid Biobank of Neuroendocrine Neoplasms Enables Genotype-Phenotype Mapping2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reconstruction of the Human Colon Epithelium In Vivo.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Divergent Routes toward Wnt and R-spondin Niche Independency during Human Gastric Carcinogenesis2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Human Pancreatic Tumor Organoids Reveal Loss of Stem Cell Niche Factor Dependence during Disease Progression.2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] オルガノイドによる胃がんニッチ非依存性獲得機構の解明2019

Author(s)

Organizer

Data Source

Nanki Kosaku 南木康作

南木康作ナンキコウサク