Masui Osamu 増井修

… Alternative Names

MASUI Osamu 増井修

Less

Researcher Number	30579305
Other IDs
Affiliation (Current)	2025: 国立研究開発法人理化学研究所, 生命医科学研究センター, 研究員
Affiliation (based on the past Project Information) *help	2021 – 2024: 国立研究開発法人理化学研究所, 生命医科学研究センター, 研究員 2015 – 2017: 国立研究開発法人理化学研究所, 統合生命医科学研究センター, 研究員 2013 – 2014: 独立行政法人理化学研究所, 統合生命医科学研究センター, 研究員 2011 – 2012: 独立行政法人理化学研究所, 免疫器官形成研究グループ, 研究員
Review Section/Research Field	Principal Investigator Basic Section 43050:Genome biology-related / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Morphology/Structure / epigenetics / System genome science
Keywords	Principal Investigator Xist / エピジェネティクス / RNA / Polycomb / Non-coding RNA / Xist RNA / non-coding RNA / X染色体不活性化 / ポリコーム複合体 / X inactivation … More / Epigenetics / Degron / PRC1 / Live-cell imaging / RADICL-seq / 遺伝子転写制御 / 生体分子 / 核酸 / 遺伝子 / Polycomb group / live-imaging / SIM / Super-resolution / ライブイメージング / 超解像顕微鏡 / 細胞分化 / ES細胞 / Ring1B / PRC1/2 / RIP / ポリコーム転写抑制複合体 Less

Role of Polycomb complexes in the initiation of X-chromosome inactivationPrincipal Investigator
- Principal Investigator
  
  増井修
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43050:Genome biology-related
- Research Institution
  Institute of Physical and Chemical Research
Role of Polycomb in tethering ncRNAs to chromatin.Principal Investigator
- Principal Investigator
  
  Masui Osamu
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Institute of Physical and Chemical Research
Super-resolution live-imaging of RNA moleculesPrincipal Investigator
- Principal Investigator
  
  Masui Osamu
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Morphology/Structure
- Research Institution
  Institute of Physical and Chemical Research
Role of RNA molecules in the polycomb complex, PRC1Principal Investigator
- Principal Investigator
  
  Masui Osamu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  epigenetics
- Research Institution
  Institute of Physical and Chemical Research
Genome - wide analysis for PRC1 - bound RNA molecules .Principal Investigator
- Principal Investigator
  
  MASUI Osamu
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  System genome science
- Research Institution
  The Institute of Physical and Chemical Research

All 2023 2021 2018 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation Book

[Book] 実験医学別冊「初めてでもできる！超解像イメージング」2016
- Author(s)
  増井修
- Total Pages
  11
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-16K14773
[Book] 実験医学２０１５年１２月増刊号「ノンコーディングRNAテキストブック」2015
- Author(s)
  増井修
- Total Pages
  7
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-25503004
[Journal Article] Polycomb repressive complexes 1 and 2 are each essential for maintenance of X inactivation in extra-embryonic lineages2023
- Author(s)
  Masui Osamu、Corbel Catherine、Nagao Koji、Endo Takaho A.、Kezuka Fuyuko、Diabangouaya Patricia、Nakayama Manabu、Kumon Mami、Koseki Yoko、Obuse Chikashi、Koseki Haruhiko、Heard Edith
- Journal Title
  
  Nature Cell Biology
  
  Volume: 25 Issue: 1 Pages: 134-144
- DOI
  10.1038/s41556-022-01047-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19241, KAKENHI-PROJECT-19H03156, KAKENHI-PLANNED-18H05532, KAKENHI-PLANNED-19H05745, KAKENHI-PLANNED-17H06426, KAKENHI-PUBLICLY-22H05599, KAKENHI-PROJECT-23K23810
[Journal Article] Live imaging of Xist RNA2018
- Author(s)
  Masui O, Heard E, Koseki H
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 印刷中
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14773
[Journal Article] PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes.2017
- Author(s)
  Endoh M, Endo TA, Shinga J, Hayashi K, Farcas A, Ma KW, Ito S, Sharif J, Endoh T, Onaga N, Nakayama M, Ishikura T, Masui O, Kessler BM, Suda T, Ohara O, Okuda A, Klose RJ, Koseki H.
- Journal Title
  
  Elife
  
  Volume: 6 Pages: 27970-27970
- DOI
  10.7554/elife.21064
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-15H05602, KAKENHI-PROJECT-16K07372, KAKENHI-PROJECT-16K14773, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-26221309
[Journal Article] PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes2017
- Author(s)
  Endoh M, Endo TA, Shinga J, Hayashi K, Farcas A, Ma KW, Ito S, Sharif J, Endoh T, Onaga N, Nakayama M, Ishikura T, Masui O, Kessler BM, Suda T, Ohara O, Okuda A, Klose RJ, Koseki H
- Journal Title
  
  Elife
  
  Volume: 6
- DOI
  10.7554/elife.27970
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14773
[Journal Article] PCGF3/5-PRC1 initiates Polycomb recruitment in X chromosome inactivation.2017
- Author(s)
  Almeida M, Pintacuda G, Masui O, Koseki Y, Gdula M, Cerase A, Brown D, Mould A, Innocent C, Nakayama M, Schermelleh L, Nesterova TB, Koseki H, Brockdorff N.
- Journal Title
  
  Science
  
  Volume: 356 Issue: 6342 Pages: 1081-1084
- DOI
  10.1126/science.aal2512
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-16K14773
[Journal Article] A Pooled shRNA Screen Identifies Rbm15, Spen, and Wtap as Factors Required for Xist RNA-Mediated Silencing2015
- Author(s)
  Moindrot B, Cerase A, Coker H, Masui O, Grijzenhout A, Pintacuda G, Schermelleh L, Nesterova TB, Brockdorff N
- Journal Title
  
  Cell Reports
  
  Volume: 12 Issue: 4 Pages: 562-572
- DOI
  10.1016/j.celrep.2015.06.053
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25503004
[Journal Article] Cdyl, a new partner of the inactive X chromosome and potential reader of H3K27me3 and H3K9me22013
- Author(s)
  Escamilla-Del-Arenal M, da Rocha ST, Spruijt CG, Masui O, Renaud O, Smits AH, Margueron R, Vermeulen M, Heard E
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 33 Issue: 24 Pages: 5005-5020
- DOI
  10.1128/mcb.00866-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25503004
[Journal Article] ポリコーム複合体と染色体・核内構造2012
- Author(s)
  増井修
- Journal Title
  
  細胞工学
  
  Volume: ３１ Pages: 887-893
- Data Source
  KAKENHI-PROJECT-23810035
[Journal Article] MicroRNA Regulation of Cbx7 Mediates a Switch of Polycomb Orthologs during ESC differentiation2012
- Author(s)
  Ana O'Loghlen、増井修, 他
- Journal Title
  
  Cell Stem Cell
  
  Volume: Vol.10 Issue: 1 Pages: 33-46
- DOI
  10.1016/j.stem.2011.12.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23810035
[Journal Article] ポリコーム複合体と染色体・核内構造2012
- Author(s)
  増井修、古関明彦
- Journal Title
  
  細胞工学
  
  Volume: vol. 31 Pages: 887-893
- Data Source
  KAKENHI-PROJECT-23810035
[Journal Article] MicroRNA regulation of Cbx7 mediates a switch of Polycomb orthologs during ESC differentiation.2012
- Author(s)
  O'Loghlen A., Mu n oz - Cabello A.M., Gaspar - Maia A., Wu H.A., Banito A., Kunows ka N., Racek T., Pemberton H.N., Beolchi P., Lavial F., Masui O. , Vermeulen M., Carroll T., Graumann J., Heard E., Dillon N., Azuara V., Snijders A.P., Peters G., Bernstein E., Gil J.
- Journal Title
  
  Cell Stem Cell.
  
  Volume: vol. 6 Pages: 33-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23810035
[Journal Article] Live-Cell Chromosome Dynamics and Outcome of X Chromosome Pairing Events during ES Cell Differentiation2011
- Author(s)
  増井修, 他
- Journal Title
  
  Cell
  
  Volume: Vol.145 Issue: 3 Pages: 447-458
- DOI
  10.1016/j.cell.2011.03.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23810035
[Presentation] Polycomb complexes PRC1 and PRC2 are each essential for maintenance of X inactivation in extra embryonic lineages2021
- Author(s)
  Osamu Masui
- Organizer
  第４４回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K19241
[Presentation] Super-resolution analysis of Xist RNA2015
- Author(s)
  Osamu Masui
- Organizer
  EMBO/EMBL symposium
- Place of Presentation
  Heidelberg, Germany
- Year and Date
  2015-10-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25503004
[Presentation] 超解像顕微鏡を用いた Xist RNA のイメージング2015
- Author(s)
  増井修
- Organizer
  第５３回日本生物物理学会大会
- Place of Presentation
  金沢大学・金沢市・石川県
- Year and Date
  2015-09-13
- Invited
- Data Source
  KAKENHI-PROJECT-25503004
[Presentation] RNA タグを利用した Xist RNA の解析2014
- Author(s)
  増井修
- Organizer
  第66回日本細胞生物学会大会
- Place of Presentation
  奈良市
- Data Source
  KAKENHI-PROJECT-25503004
[Presentation] Live-cell imaging of Xist RNA2013
- Author(s)
  Masui O
- Organizer
  EMBO Conference Series: Nuclear Structure and Dynamics
- Place of Presentation
  L'Isle sur la Sorgue, France
- Data Source
  KAKENHI-PROJECT-25503004
[Presentation] Live - cell imaging of X - chromosome inactivation in differentiating ES cells: visualisation of X - inactivation centre locus and Xist RNA2012
- Author(s)
  増井修
- Organizer
  2012 Mouse Molecular Genetics Conference
- Place of Presentation
  Pacific Grove (USA)
- Data Source
  KAKENHI-PROJECT-23810035
[Presentation] Live-cell imaging of X-chromosome inactivation in differentiating ES cells: visualisation of X-inactivation centre locus and Xist RNA2012
- Author(s)
  Osamu Masui
- Organizer
  2012 Mouse Molecular Genetics Conference
- Place of Presentation
  Pacific Grove, CA, USA
- Data Source
  KAKENHI-PROJECT-23810035
[Presentation] RNA タグを利用した Xist RNA の解析
- Author(s)
  増井修
- Organizer
  第６６回日本細胞生物学会大会
- Place of Presentation
  奈良県新公会堂
- Year and Date
  2014-06-11 – 2014-06-13
- Invited
- Data Source
  KAKENHI-PROJECT-25503004

1. 加藤雅紀 (10625437)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 長尾恒治 (60426575)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. KEPTEN Eldad

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 古関明彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Masui Osamu 増井 修

MASUI Osamu 増井 修

Research Projects

Research Products

Co-Researchers

Role of Polycomb complexes in the initiation of X-chromosome inactivationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of Polycomb in tethering ncRNAs to chromatin.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Super-resolution live-imaging of RNA moleculesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of RNA molecules in the polycomb complex, PRC1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Genome - wide analysis for PRC1 - bound RNA molecules .Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 実験医学別冊「初めてでもできる！ 超解像イメージング」2016

Author(s)

Total Pages

Publisher

Data Source

[Book] 実験医学２０１５年１２月増刊号「ノンコーディングRNAテキストブック」2015

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Polycomb repressive complexes 1 and 2 are each essential for maintenance of X inactivation in extra-embryonic lineages2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Live imaging of Xist RNA2018

Author(s)

Journal Title

Data Source

[Journal Article] PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PCGF3/5-PRC1 initiates Polycomb recruitment in X chromosome inactivation.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Pooled shRNA Screen Identifies Rbm15, Spen, and Wtap as Factors Required for Xist RNA-Mediated Silencing2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cdyl, a new partner of the inactive X chromosome and potential reader of H3K27me3 and H3K9me22013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ポリコーム複合体と染色体・核内構造2012

Masui Osamu 増井修

MASUI Osamu 増井修

[Book] 実験医学別冊「初めてでもできる！超解像イメージング」2016