HIGAKI TAKAYA 檜垣貴哉

… Alternative Names

Higaki Takaya 檜垣貴哉

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Researcher Number	30587407
Other IDs
Affiliation (Current)	2025: 川崎医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2015 – 2020: 岡山大学, 大学病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 56050:Otorhinolaryngology-related / Otorhinolaryngology Except Principal Investigator Otorhinolaryngology
Keywords	Principal Investigator 好酸球性副鼻腔炎 / アスピリン喘息 / アスピリン不耐症 / IL-22受容体 / 慢性副鼻腔炎 / 好酸球 / IL-22 / IFN-γ / Lineage / CD127 … More / 鼻茸 / IL-13 / IL-5 / 自然リンパ球 … More Except Principal Investigator 微生物 / シグナル伝達 / 免疫学 / アレルギー / マクロファージ / サイトカイン / 中耳炎 / 炎症 / コホート研究 / スギ花粉症 / プロテオーム / 予測 / VAS / 症状薬物スコア / 単球 / マイクロバイオーム / 効果予測 / アレルギー性鼻炎 / IL-10 / 唾液 / 舌下免疫療法 Less

Analysis of the IL-22 regulation in Eosinophilic Rhinosinusitis with aspirin intolerancePrincipal Investigator
- Principal Investigator
  
  Higaki Takaya
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Okayama University
Role of macrophage migration inhibitory factor in otitis media
- Principal Investigator
  
  Kariya Shin
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Okayama University
Expression of innate lympgoid cell and its response to microbial components in eosinophilic upper airway inflammationPrincipal Investigator
- Principal Investigator
  
  Higaki Takaya
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Okayama University
Development of predicting factor for the efficacy of sublingual immunotherapy for Japanese cedar pollinosis using saliva
- Principal Investigator
  
  Okano Mitsuhiro
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Okayama University

All 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] INVOLVEMENT OF IL-22 AND IL-22 RECEPTOR SIGNALING TO THE EOSINOPHILIC INFLAMMATION OF CHRONIC RHINOSINUSITIS2020
- Author(s)
  檜垣貴哉
- Journal Title
  
  Japanese Journal of Allergology
  
  Volume: 69 Issue: 9 Pages: 897-899
- DOI
  10.15036/arerugi.69.897
- NAID
  130007938961
- ISSN
  0021-4884, 1347-7935
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-18K16891
[Journal Article] Role of Macrophage Migration Inhibitory Factor in NLRP3 Inflammasome Expression in Otitis Media2020
- Author(s)
  Shin Kariya, Mitsuhiro Okano, Pengfei Zhao, Yukihide Maeda, Yuko Kataoka, Takaya Higaki, Seiichiro Makihara, Jun Nishihira, Tomoyasu Tachibana, Kazunori Nishizaki
- Journal Title
  
  Otology & Neurotology
  
  Volume: 41 Issue: 3 Pages: 364-370
- DOI
  10.1097/mao.0000000000002537
- NAID
  120006886944
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11329
[Journal Article] Role of whole saliva in the efficacy of sublingual immunotherapy in seasonal allergic rhinitis2019
- Author(s)
  Haruna T, Kariya S, Fujiwara T, Yuta A, Higaki T, Zhao P, Ogawa Y, Kanai K, Hitara Y, Oka A, Nishizaki K, Okano M.
- Journal Title
  
  Allergol. Int.
  
  Volume: 68 Issue: 1 Pages: 82-89
- DOI
  10.1016/j.alit.2018.07.008
- NAID
  130007557867
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04987
[Journal Article] NLRP3 inflammasome expression in lipopolysaccharide-induced otitis media.2018
- Author(s)
  Shin Kariya, Mitsuhiro Okano, Pengfei Zhao, Yukihide Maeda, Yuko Kataoka, Takaya Higaki, Yohei Noda, Seiichiro Makihara, Kazunori Nishizaki
- Journal Title
  
  Acta Otolaryngol.
  
  Volume: 138 Issue: 12 Pages: 1061-1065
- DOI
  10.1080/00016489.2018.1515499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11329
[Journal Article] The impact of chronic rhinosinusitis on long-term survival in lung transplantation recipients2017
- Author(s)
  Kariya S, Okano M, Oto T, Higaki T, Haruna T, Noda Y, Nishizaki K.
- Journal Title
  
  Acta Oto-Laryngologica
  
  Volume: 137 Issue: 5 Pages: 529-533
- DOI
  10.1080/00016489.2016.1247497
- NAID
  120006463734
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K20210, KAKENHI-PROJECT-16K15721
[Journal Article] Effect of intranasal corticosteroid on pre-onset activation of eosinophils and mast cells in experimental Japanese cedar pollinosis2016
- Author(s)
  Noyama Y, Okano M, Fujiwara T, Kariya S, Makihara S, Haruna T, Kanai K, Higaki T, Nishizaki K.
- Journal Title
  
  Allergol. Int.
  
  Volume: 65 Issue: 3 Pages: 259-265
- DOI
  10.1016/j.alit.2015.12.007
- NAID
  130005165879
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25861563, KAKENHI-PROJECT-15K20210, KAKENHI-PROJECT-15H04987
[Journal Article] IL-22/IL-22R1 signaling regulates the pathophysiology of chronic rhinosinusitis with nasal polyps via alteration of MUC1 expression.2016
- Author(s)
  Noyama Y, Okano M, Fujiwara T, Kariya S, Higaki T, Haruna T, Makihara S, Kanai K, Koyama T, Taniguchi M, Ishitoya J, Kanda A, Kobayashi Y, Asako M, Tomoda K, Nishizaki K.
- Journal Title
  
  Allergology International
  
  Volume: 印刷中
- NAID
  130005308495
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K20210
[Journal Article] Regulatory effect of TLR3 signaling on staphylococcal enterotoxin-induced IL-5, IL-13, IL-17A and IFN-γ production in chronic rhinosinusitis with nasal polyps2016
- Author(s)
  Okano M, Fujiwara T, Kariya S, Higaki T, Makihara S, Haruna T, Noyama Y, Koyama T, Omichi R, Orita Y, Miki K, Kanai K, Nishizaki K.
- Journal Title
  
  Allergol. Int.
  
  Volume: 65 Issue: 1 Pages: 96-102
- DOI
  10.1016/j.alit.2015.08.005
- NAID
  130005290330
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20210, KAKENHI-PROJECT-15H04987, KAKENHI-PROJECT-26670742, KAKENHI-PROJECT-25861562, KAKENHI-PROJECT-16K15721
[Journal Article] Staphylococcal protein A-formulated immune complexes suppress enterotoxin-induced cellular responses in nasal polyps.2015
- Author(s)
  Okano M, Fujiwara T, Kariya S, Haruna T, Higaki T, Noyama Y, Makihara SI, Kanai K, Nishizaki K.
- Journal Title
  
  Journal of Allergy and Clinical Immunology
  
  Volume: ━ Issue: 2 Pages: 343-350
- DOI
  10.1016/j.jaci.2014.10.058
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25861562, KAKENHI-PROJECT-25861563, KAKENHI-PROJECT-26670742, KAKENHI-PROJECT-15K20210, KAKENHI-PROJECT-15H04987
[Journal Article] Pulmonary function in never-smoker patients with chronic rhinosinusitis.2015
- Author(s)
  Kariya S, Okano M, Higaki T, Noyama Y, Haruna T, Nishizaki K.
- Journal Title
  
  International Forum of Allergy and Rhinology
  
  Volume: 5 Issue: 11 Pages: 990-995
- DOI
  10.1002/alr.21628
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K20210, KAKENHI-PROJECT-26670742, KAKENHI-PROJECT-25861562
[Presentation] 好酸球性上気道炎症におけるIL-22およびIL-22受容体発現の制御作用についての解析2019
- Author(s)
  檜垣貴哉、岡野光博、野田実里、春名威範、假谷伸、西﨑和則
- Organizer
  第37回　日本耳鼻咽喉科免疫アレルギー学会
- Data Source
  KAKENHI-PROJECT-18K16891
[Presentation] Involvement of IL-22 and IL-22 receptor signaling to the eosinophilic inflammation of chronic rhinosinusitis2019
- Author(s)
  Takaya Higaki, Mitsuhiro Okano, Minori Noda, Shin Kariya, Takahisa Koyama, Kazunori Nishizaki
- Organizer
  CEORL-HNS 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16891
[Presentation] IL-22、IL-22受容体の好酸球性副鼻腔炎病態への関与について2018
- Author(s)
  檜垣貴哉
- Organizer
  第57回　日本鼻科学会
- Data Source
  KAKENHI-PROJECT-18K16891
[Presentation] IL-31とアレルギー性鼻炎に関する新知見2016
- Author(s)
  檜垣貴哉
- Organizer
  第65回　日本アレルギー学会・学術大会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-15K20210
[Presentation] 唾液によるヒト末梢血単球からのIL-10産生誘導作用2016
- Author(s)
  岡野光博，仮谷伸，檜垣貴哉，春名威範，金井健吾，野山和廉，小山貴久，牧原靖一郎，西﨑和則
- Organizer
  日本耳鼻咽喉科学会総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-15H04987
[Presentation] マウスアレルギー性鼻炎モデルにおけるMinimal Persistent Inflammationの検討2016
- Author(s)
  檜垣貴哉、岡野光博、藤原瑠美、小山貴久、金井健吾、野山和廉、春名威範、假谷伸、西﨑和則
- Organizer
  第34回日本耳鼻咽喉科免疫アレルギー学会
- Place of Presentation
  鳥羽国際ホテル
- Year and Date
  2016-02-05
- Data Source
  KAKENHI-PROJECT-15K20210
[Presentation] ヒト末梢血における2型自然リンパ球の機能についての解析2016
- Author(s)
  檜垣貴哉，岡野光博，小山貴久，大道亮太郎，春名威範，假谷伸，西﨑和則
- Organizer
  第55回日本鼻科学会総会・学術講演会
- Place of Presentation
  栃木県総合文化センター
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K20210
[Presentation] スギ花粉症に対する鼻噴霧用ステロイド薬初期療法の医療経済学的評価2015
- Author(s)
  岡野光博、檜垣貴哉、春名威範、假谷　伸、野山和廉、小山貴久、藤原瑠美、趙　鵬飛、牧原靖一郎、金井健吾、西﨑和則
- Organizer
  日本耳鼻咽喉科免疫アレルギー学会
- Place of Presentation
  鳥羽市（三重県）
- Year and Date
  2015-10-23
- Data Source
  KAKENHI-PROJECT-15H04987
[Presentation] 鼻茸分離細胞を用いたPam3CSK4がサイトカイン産生に与える影響の検討2015
- Author(s)
  檜垣貴哉、岡野光博、藤原瑠美、小山貴久、野山和廉、春名威範、野田洋平、假谷伸、西﨑和則
- Organizer
  第54回日本鼻科学会総会・学術講演会
- Place of Presentation
  広島国際会議場
- Year and Date
  2015-10-01
- Data Source
  KAKENHI-PROJECT-15K20210

1. Okano Mitsuhiro (60304359)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. Kariya Shin (10274226)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. 春名威範 (70646182)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. 野山和廉 (80646183)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

HIGAKI TAKAYA 檜垣 貴哉

Higaki Takaya 檜垣 貴哉

Research Projects

Research Products

Co-Researchers

Analysis of the IL-22 regulation in Eosinophilic Rhinosinusitis with aspirin intolerancePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of macrophage migration inhibitory factor in otitis media

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Expression of innate lympgoid cell and its response to microbial components in eosinophilic upper airway inflammationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of predicting factor for the efficacy of sublingual immunotherapy for Japanese cedar pollinosis using saliva

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] INVOLVEMENT OF IL-22 AND IL-22 RECEPTOR SIGNALING TO THE EOSINOPHILIC INFLAMMATION OF CHRONIC RHINOSINUSITIS2020

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Role of Macrophage Migration Inhibitory Factor in NLRP3 Inflammasome Expression in Otitis Media2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Role of whole saliva in the efficacy of sublingual immunotherapy in seasonal allergic rhinitis2019

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] NLRP3 inflammasome expression in lipopolysaccharide-induced otitis media.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The impact of chronic rhinosinusitis on long-term survival in lung transplantation recipients2017

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Effect of intranasal corticosteroid on pre-onset activation of eosinophils and mast cells in experimental Japanese cedar pollinosis2016

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] IL-22/IL-22R1 signaling regulates the pathophysiology of chronic rhinosinusitis with nasal polyps via alteration of MUC1 expression.2016

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Regulatory effect of TLR3 signaling on staphylococcal enterotoxin-induced IL-5, IL-13, IL-17A and IFN-&gamma; production in chronic rhinosinusitis with nasal polyps2016

Author(s)

Journal Title

DOI

NAID

HIGAKI TAKAYA 檜垣貴哉

Higaki Takaya 檜垣貴哉

[Journal Article] Regulatory effect of TLR3 signaling on staphylococcal enterotoxin-induced IL-5, IL-13, IL-17A and IFN-γ production in chronic rhinosinusitis with nasal polyps2016