Yanagiya Akiko 柳谷朗子

Researcher Number	30608138
Other IDs	https://orcid.org/0000-0002-5553-0311
Affiliation (based on the past Project Information) *help	2020 – 2022: 沖縄科学技術大学院大学, 細胞シグナルユニット, スタッフサイエンティスト 2018 – 2020: 沖縄科学技術大学院大学, 細胞シグナルユニット, 研究員
Review Section/Research Field	Principal Investigator Basic Section 49010:Pathological biochemistry-related / Biological Sciences
Keywords	Principal Investigator 膵β細胞 / CCR4-NOT複合体 / mRNA分解 / 転写後制御 / インスリン生合成 / 恒常性維持 / オートファジー / m6A修飾 / 転写後調節 / CR4-NOT複合体 / 脱アデニル化

Research Projects
(3 results)
Research Products
(11 results)

Post-transcriptional regulation mediated by m6A modification to maintain pancreatic beta cell homeostasisPrincipal Investigator
- Principal Investigator
  
  柳谷朗子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Okinawa Institute of Science and Technology Graduate University
The post-transcriptional regulation of autophagy as a key determinant of physiological homeostasis in pancreatic beta cells.Principal Investigator
- Principal Investigator
  
  柳谷朗子
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Okinawa Institute of Science and Technology Graduate University
Post-transcriptional regulation in glucose-induced insulin secretion by the CCR4-NOT deadenylase complex in mouse pancreatic beta cellsPrincipal Investigator
- Principal Investigator
  
  Yanagiya Akiko
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Okinawa Institute of Science and Technology Graduate University

All 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] CNOT7 Outcompetes Its Paralog CNOT8 for Integration into The CCR4-NOT Complex.2022
- Author(s)
  Patrick N Stoney , Akiko Yanagiya , Saori Nishijima , Tadashi Yamamoto
- Journal Title
  
  Journal of molecular biology
  
  Volume: 434 Issue: 9 Pages: 167523-167523
- DOI
  10.1016/j.jmb.2022.167523
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06975
[Journal Article] Neuronal XRN1 is required for maintenance of whole-body metabolic homeostasis.2021
- Author(s)
  Shohei Takaoka , Akiko Yanagiya , Haytham Mohamed Aly Mohamed , Rei Higa , Takaya Abe , Ken-Ichi Inoue , Akinori Takahashi , Patrick Stoney , Tadashi Yamamoto
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 10 Pages: 103151-103151
- DOI
  10.1016/j.isci.2021.103151
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06975
[Journal Article] Essential functions of the CNOT7/8 catalytic subunits of the CCR4-NOT complex in mRNA regulation and cell viability2020
- Author(s)
  Mostafa Dina、Takahashi Akinori、Yanagiya Akiko、Yamaguchi Tomokazu、Abe Takaya、Kureha Taku、Kuba Keiji、Kanegae Yumi、Furuta Yasuhide、Yamamoto Tadashi、Suzuki Toru
- Journal Title
  
  RNA Biology
  
  Volume: 17 Issue: 3 Pages: 403-416
- DOI
  10.1080/15476286.2019.1709747
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06975, KAKENHI-PROJECT-18K07079, KAKENHI-PROJECT-17H04028, KAKENHI-PROJECT-18K15038, KAKENHI-PROJECT-20K08195
[Journal Article] Loss of β-cell identity and diabetic phenotype in mice caused by disruption of CNOT3-dependent mRNA deadenylation.2020
- Author(s)
  Mostafa D, Yanagiya A, Georgiadou E, Wu Y, Stylianides T, Rutter GA, Suzuki T*, Yamamoto T*
- Journal Title
  
  Communications biology.
  
  Volume: 476 Issue: 1 Pages: 1-16
- DOI
  10.1038/s42003-020-01201-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06975, KAKENHI-PROJECT-18K07079, KAKENHI-PROJECT-18H02425
[Journal Article] The CCR4-NOT complex maintains liver homeostasis through mRNA deadenylation2020
- Author(s)
  Takahashi Akinori、Suzuki Toru、Soeda Shou、Takaoka Shohei、Kobori Shungo、Yamaguchi Tomokazu、Mohamed Haytham Mohamed Aly、Yanagiya Akiko、Abe Takaya、Shigeta Mayo、Furuta Yasuhide、Kuba Keiji、Yamamoto Tadashi
- Journal Title
  
  Life Science Alliance
  
  Volume: 3 Issue: 5 Pages: 1-19
- DOI
  10.26508/lsa.201900494
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06975, KAKENHI-PROJECT-18K07079, KAKENHI-PROJECT-20K07285, KAKENHI-PROJECT-20K21566, KAKENHI-PROJECT-20H03426
[Presentation] Translational control is a potential therapeutic target to cure a variety of diseases: Translational control of m6A-methylated mRNAs to maintain pancreatic β cell homeostasis2021
- Author(s)
  Akiko Yanagiya, Yuki Tara, Tadashi Yamamoto
- Organizer
  The 44th the Molecular Biology Society of Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H05351
[Presentation] 膵β細胞の恒常性維持に重要なCCR4-NOT複合体を介したmRNA分解制御の解析2021
- Author(s)
  Akiko Yanagiya
- Organizer
  The 11th Signaling network meeting
- Invited
- Data Source
  KAKENHI-PROJECT-18K06975
[Presentation] Translational control by poly(A)-binding protein in glucose-stimulated insulin biosynthesis in diabetes2020
- Author(s)
  Akiko Yanagiya
- Organizer
  43rd Annual Meeting of the Molecular Biology Society of Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06975
[Presentation] Post-transcriptional regulation to maintain redox homeostasis in insulin biosynthesis by the Ccr4-Not deadenylase complex in mouse pancreatic β-cells2019
- Author(s)
  Akiko Yanagiya, Tadashi Yamamoto
- Organizer
  8th RNA Stability Conference: mRNA Turnover Mechanisms, Regulation and their Implication in Infectious and Age-Related Diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06975
[Presentation] Post-transcriptional regulation maintains redox homeostasis in insulin biosynthesis by the Ccr4-Not deadenylase complex2019
- Author(s)
  Akiko Yanagiya, Tadashi Yamamoto
- Organizer
  第21回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-18K06975
[Presentation] Post-transcriptional regulation in insulin biosynthesis by the Ccr4-Not deadenylase complex in mouse pancreatic β cells2019
- Author(s)
  Akiko Yanagiya, Tadashi Yamamoto
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06975

Yanagiya Akiko 柳谷 朗子

Research Projects

Research Products

Post-transcriptional regulation mediated by m6A modification to maintain pancreatic beta cell homeostasisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The post-transcriptional regulation of autophagy as a key determinant of physiological homeostasis in pancreatic beta cells.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Post-transcriptional regulation in glucose-induced insulin secretion by the CCR4-NOT deadenylase complex in mouse pancreatic beta cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] CNOT7 Outcompetes Its Paralog CNOT8 for Integration into The CCR4-NOT Complex.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Neuronal XRN1 is required for maintenance of whole-body metabolic homeostasis.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Essential functions of the CNOT7/8 catalytic subunits of the CCR4-NOT complex in mRNA regulation and cell viability2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Loss of β-cell identity and diabetic phenotype in mice caused by disruption of CNOT3-dependent mRNA deadenylation.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The CCR4-NOT complex maintains liver homeostasis through mRNA deadenylation2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] Translational control is a potential therapeutic target to cure a variety of diseases: Translational control of m6A-methylated mRNAs to maintain pancreatic β cell homeostasis2021

Author(s)

Organizer

Data Source

[Presentation] 膵β細胞の恒常性維持に重要なCCR4-NOT複合体を介したmRNA分解制御の解析2021

Author(s)

Organizer

Data Source

[Presentation] Translational control by poly(A)-binding protein in glucose-stimulated insulin biosynthesis in diabetes2020

Author(s)

Organizer

Data Source

[Presentation] Post-transcriptional regulation to maintain redox homeostasis in insulin biosynthesis by the Ccr4-Not deadenylase complex in mouse pancreatic β-cells2019

Author(s)

Organizer

Data Source

[Presentation] Post-transcriptional regulation maintains redox homeostasis in insulin biosynthesis by the Ccr4-Not deadenylase complex2019

Author(s)

Organizer

Data Source

[Presentation] Post-transcriptional regulation in insulin biosynthesis by the Ccr4-Not deadenylase complex in mouse pancreatic β cells2019

Author(s)

Organizer

Data Source

Yanagiya Akiko 柳谷朗子