TANEIKE Manabu 種池学

Researcher Number	30609756
Other IDs	https://orcid.org/0000-0002-4550-091X
Affiliation (Current)	2025: 奈良先端科学技術大学院大学, 学内共同利用施設等, 教授 2025: 大阪大学, 大学院医学系研究科, 招へい教授
Affiliation (based on the past Project Information) *help	2023: 大阪大学, 大学院医学系研究科, 講師 2022: 大阪大学, 大学院医学系研究科, 助教 2020 – 2021: 大阪大学, 医学系研究科, 助教 2018 – 2019: 大阪大学, キャンパスライフ健康支援センター, 助教
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related / 0903:Organ-based internal medicine and related fields Except Principal Investigator Basic Section 53020:Cardiology-related / Cardiovascular medicine
Keywords	Principal Investigator 心不全 / 無菌性炎症 / 拡張機能障害 / 心筋炎症 / 脂質メディエーター / 細胞死 / オートファジー / エンドサイトーシス / β受容体 Except Principal Investigator 心不全 … More / 心筋炎症 / ミトコンドリア / 炎症 / β受容体 / ダウンレギュレーション / β1アドレナリン受容体 / DNAメチル化 / マイトファジー / DNA分解 / 循環器・高血圧 / 心肥大 / 老化 / アドレナリン受容体 / 線維芽細胞 / 心臓老化 Less

HFpEF発症進展機構における無菌性炎症の役割の解明と新規治療法開発への応用Principal Investigator
- Principal Investigator
  
  種池学
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Osaka University
Elucidation of mitochondrial degradation mechanisms and their application to drug development for heart failure
- Principal Investigator
  
  Kinya Otsu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  National Cardiovascular Center Research Institute
心筋細胞内β受容体リサイクリング機構の解明と心不全創薬への応用
- Principal Investigator
  
  中山博之
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Osaka University
The role of a lipid mediator on cardiac cell death in the pathogenesis of heart failurePrincipal Investigator
- Principal Investigator
  
  TANEIKE Manabu
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Osaka University
Investigation for a molecular regulatory mechanism inducing endogenous myocardial inflammation
- Principal Investigator
  
  OTSU Kinya
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Osaka University
The regulatory mechanism of autophagy by Rubicon in the heartPrincipal Investigator
- Principal Investigator
  
  TANEIKE Manabu
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0903:Organ-based internal medicine and related fields
- Research Institution
  Osaka University
The role of beta adrenergic signaling in fibroblasts during cardiac senescence
- Principal Investigator
  
  NAKAYAMA Hiroyuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Osaka University

All 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Lysophosphatidylserine induces necrosis in pressure overloaded male mouse hearts via G protein coupled receptor 342023
- Author(s)
  Sugihara Ryuta、Taneike Manabu、Murakawa Tomokazu、Tamai Takahito、Ueda Hiromichi、Kitazume-Taneike Rika、Oka Takafumi、Akazawa Yasuhiro、Nishida Hiroki、Mine Kentaro、Hioki Ayana、Omi Jumpei、Omiya Shigemiki、Aoki Junken、Ikeda Kazutaka、Nishida Kazuhiko、Arita Makoto、Yamaguchi Osamu、Sakata Yasushi、Otsu Kinya
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 4494-4494
- DOI
  10.1038/s41467-023-40201-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K21350, KAKENHI-PROJECT-20K08491, KAKENHI-PROJECT-22KJ0530, KAKENHI-PROJECT-22H00438
[Journal Article] Rubicon-regulated beta-1 adrenergic receptor recycling protects the heart from pressure overload2022
- Author(s)
  Akazawa Yasuhiro、Taneike Manabu、Ueda Hiromichi、Kitazume-Taneike Rika、Murakawa Tomokazu、Sugihara Ryuta、Yorifuji Hiroki、Nishida Hiroki、Mine Kentaro、Hioki Ayana、Omiya Shigemiki、Nakayama Hiroyuki、Yamaguchi Osamu、Yoshimori Tamotsu、Sakata Yasushi、Otsu Kinya
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 41-41
- DOI
  10.1038/s41598-021-03920-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02913, KAKENHI-PROJECT-20K08448, KAKENHI-PROJECT-20K08491, KAKENHI-PROJECT-21K08104, KAKENHI-PROJECT-21K21350
[Journal Article] Iron derived from autophagy-mediated ferritin degradation induces cardiomyocyte death and heart failure in mice2021
- Author(s)
  Ito Jumpei、Omiya Shigemiki、Rusu Mara-Camelia、Ueda Hiromichi、Murakawa Tomokazu、Tanada Yohei、Abe Hajime、Nakahara Kazuki、Asahi Michio、Taneike Manabu、Nishida Kazuhiko、Shah Ajay M、Otsu Kinya
- Journal Title
  
  eLife
  
  Volume: 10
- DOI
  10.7554/elife.62174
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02807
[Journal Article] Cytokine mRNA Degradation in Cardiomyocytes Restrains Sterile Inflammation in Pressure-Overloaded Hearts2020
- Author(s)
  Omiya Shigemiki、Omori Yosuke、Taneike Manabu、Murakawa Tomokazu、Ito Jumpei、Tanada Yohei、Nishida Kazuhiko、Yamaguchi Osamu、Satoh Takashi、Shah Ajay M.、Akira Shizuo、Otsu Kinya
- Journal Title
  
  Circulation
  
  Volume: 141 Issue: 8 Pages: 667-677
- DOI
  10.1161/circulationaha.119.044582
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02807
[Journal Article] Administration of a TLR9 Inhibitor Attenuates the Development and Progression of Heart Failure in Mice2019
- Author(s)
  Hiromichi Ueda, Osamu Yamaguchi, Manabu Taneike, Yasuhiro Akazawa, Haruko Wada-Kobayashi, Ryuta Sugihara, Hiroki Yorifuji, Hiroyuki Nakayama, Shigemiki Omiya, MD, Tomokazu Murakawa, Yasushi Sakata, Kinya Otsu
- Journal Title
  
  J Am Coll Cardiol Basic Trans Science
  
  Volume: 印刷中
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02807
[Presentation] Pressure overload induces phospholipase A2-mediated lysophosphatidylserine production, leading to necrotic cardiomyocyte death and heart failure via G protein-coupled receptor 342023
- Author(s)
  Ryuta Sugihara, Manabu Taneike, Tomokazu Murakawa, Kinya Otsu, Yasushi Sakata
- Organizer
  The 7th JCS Council Forum on Basic Cardiovascular Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08491
[Presentation] Non-apoptotic Cell Death Induced by a Lipid Mediator in the Development of Heart Failure2023
- Author(s)
  種池　学
- Organizer
  第87回日本循環器学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08491
[Presentation] Ferritin degradation mediated by autophagyleads to cardiomyocyte death and heart failure by inducing iron release in mouse pressure-overload hearts2021
- Author(s)
  種池学
- Organizer
  第37回国際心臓研究学会日本部会
- Data Source
  KAKENHI-PROJECT-18H02807

1. OTSU Kinya (20294051)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
2. NAKAYAMA Hiroyuki (40581062)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 山口修 (90467580)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. 上田宏達 (30865746)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 村川智一 (50902194)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 大宮茂幹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TANEIKE Manabu 種池 学

Research Projects

Research Products

Co-Researchers

HFpEF発症進展機構における無菌性炎症の役割の解明と新規治療法開発への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of mitochondrial degradation mechanisms and their application to drug development for heart failure

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

心筋細胞内β受容体リサイクリング機構の解明と心不全創薬への応用

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of a lipid mediator on cardiac cell death in the pathogenesis of heart failurePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation for a molecular regulatory mechanism inducing endogenous myocardial inflammation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The regulatory mechanism of autophagy by Rubicon in the heartPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of beta adrenergic signaling in fibroblasts during cardiac senescence

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Lysophosphatidylserine induces necrosis in pressure overloaded male mouse hearts via G protein coupled receptor 342023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Rubicon-regulated beta-1 adrenergic receptor recycling protects the heart from pressure overload2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Iron derived from autophagy-mediated ferritin degradation induces cardiomyocyte death and heart failure in mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cytokine mRNA Degradation in Cardiomyocytes Restrains Sterile Inflammation in Pressure-Overloaded Hearts2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Administration of a TLR9 Inhibitor Attenuates the Development and Progression of Heart Failure in Mice2019

Author(s)

Journal Title

Data Source

[Presentation] Pressure overload induces phospholipase A2-mediated lysophosphatidylserine production, leading to necrotic cardiomyocyte death and heart failure via G protein-coupled receptor 342023

Author(s)

Organizer

Data Source

[Presentation] Non-apoptotic Cell Death Induced by a Lipid Mediator in the Development of Heart Failure2023

Author(s)

Organizer

Data Source

[Presentation] Ferritin degradation mediated by autophagyleads to cardiomyocyte death and heart failure by inducing iron release in mouse pressure-overload hearts2021

Author(s)

TANEIKE Manabu 種池学