Koga Tomoaki 古賀友紹

… Alternative Names

KOGA Tomoaki 古賀友紹

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Researcher Number	30615092
Other IDs	https://orcid.org/0000-0001-9584-2611
Affiliation (Current)	2025: 熊本大学, 発生医学研究所, 講師 2025: 順天堂大学, 医学部, 非常勤講師
Affiliation (based on the past Project Information) *help	2021 – 2024: 熊本大学, 発生医学研究所, 講師 2017 – 2020: 熊本大学, 発生医学研究所, 助教 2017: 順天堂大学, 大学院医学研究科, 助教 2016: 熊本大学, 大学院先導機構, 助教 2016: 熊本大学, 大学院先導機構, 特定事業教員 … More 2012 – 2015: 順天堂大学, 医学(系)研究科(研究院), 助教 2012: 順天堂大学, 医学部, 助教 2011: 九州大学, 医学研究院, 特任助教 Less
Review Section/Research Field	Principal Investigator Pathological medical chemistry / General medical chemistry / Medium-sized Section 49:Pathology, infection/immunology, and related fields / Basic Section 49010:Pathological biochemistry-related / Basic Section 48040:Medical biochemistry-related Except Principal Investigator Basic Section 59040:Nutrition science and health science-related / Medium-sized Section 50:Oncology and related fields / Pathological medical chemistry
Keywords	Principal Investigator 生理活性脂質 / 樹状細胞 / GPCR / マクロファージ / LTB4 / BLT1 / エピジェネティクス / ヒストン修飾 / 細胞記憶 / エピゲノム … More / 炎症メモリー / 免疫細胞 / 炎症 / ロイコトリエンB4 / 脂質免疫学 / コンディショナルノックアウト / T細胞 / 多階層オミクス / EpiFLUX-seq / 慢性腎臓病 / アルツハイマー病 / 遺伝子改変マウス / 代謝 / ヒストン脱メチル化酵素 / 脂質 / ヒストンメチル化 / 炎症反応 / 脂質エピゲノム / 肥満 / 脂質メディエーター / LTA4水解酵素 / LTA4H / RAGE / リピドミクス / 好中球 / 免疫応答 / 脂質免疫 / T 細胞 … More Except Principal Investigator 免疫制御 / ウイルス感染 / 生体防御 / 筋萎縮 / 乳酸アシドーシス / 高血糖 / 代謝 / 遺伝子 / エピゲノム / 胆管細胞癌 / 生理活性 / 非ステロイド性消炎鎮痛剤 / アラキドン酸 / バリア機能 / シグナル伝達 / 生体分子 / 生理活性脂質 Less

生体防御システムにおける骨格筋の新たな役割
- Principal Investigator
  
  藤巻慎
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kumamoto University
Development of novel therapeutic strategies of chronic inflammatory diseases by using inflammatory memory cell visualizing mousePrincipal Investigator
- Principal Investigator
  
  古賀友紹
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Kumamoto University
シン・マルチエピゲノム解析を基盤とした免疫細胞の多階層オミクス解析Principal Investigator
- Principal Investigator
  
  古賀友紹
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Kumamoto University
Elucidation of Epigenome network for regulating inflammation memoryPrincipal Investigator
- Principal Investigator
  
  KOGA Tomoaki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Kumamoto University
Analysis of epigenome and metabolic phenotypes in Thai liver fluke-associated cholangiocarcinoma
- Principal Investigator
  
  NAKAO MITSUYOSHI
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Kumamoto University
Biochemical elucidation of LTA4 hydrolase in immune cellsPrincipal Investigator
- Principal Investigator
  
  KOGA TOMOAKI
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kumamoto University
Elucidation of leukotriene B4 receptor 1, BLT1-dependent immune response by dendritic cells and neutrophilsPrincipal Investigator
- Principal Investigator
  
  KOGA TOMOAKI
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kumamoto University
  Juntendo University
The roles of receptors for lipid mediators in inflammation, immunity and barrier function
- Principal Investigator
  
  Yokomizo Takehiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Juntendo University
Elucidation of novel DC subset defined by expression of BLT1Principal Investigator
- Principal Investigator
  
  KOGA TOMOAKI
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Juntendo University
The role of Leukotrine B4 in dendritic cell-T cell interactionPrincipal Investigator
- Principal Investigator
  
  KOGA Tomoaki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  General medical chemistry
- Research Institution
  Juntendo University
  Kyushu University

[Book] 臨床免疫・アレルギー科　第70巻ロイコトリエンB4とその受容体による免疫調節機構2018
- Author(s)
  古賀友紹, 佐伯和子, 横溝岳彦.
- Total Pages
  10
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-17K08664
[Book] 医学のあゆみ256巻5号　GPCR研究の最前線2016「ロイコトリエン受容体」2016
- Author(s)
  市木貴子, 古賀友紹, 横溝岳彦
- Total Pages
  10
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-15K19032
[Book] 「疾患モデルの作製と利用―脂質代謝異常と関連疾患」下巻　第5章　脂質メディエーター、第4節　ロイコトリエン2015
- Author(s)
  古賀友紹, 横溝岳彦
- Total Pages
  9
- Publisher
  エルアイシー出版
- Data Source
  KAKENHI-PROJECT-15K19032
[Book] 疾患モデルの作製と利用ー脂質代謝異常と関連疾患ー2015
- Author(s)
  古賀友紹、横溝岳彦
- Publisher
  エルアイシー出版
- Data Source
  KAKENHI-PROJECT-25860223
[Book] Leukotriene B4 Receptors. In “Bioactive Lipid Mediators: Current Reviews and Protocols” (Murakami M, Yokomizo T, Ed)2015
- Author(s)
  Koga T, Yokomizo T
- Total Pages
  9
- Publisher
  Springer (Tokyo)
- Data Source
  KAKENHI-PROJECT-15K19032
[Book] 雑誌「生化学」書評：イラストレイテッドハーパー・生化学原著29版2014
- Author(s)
  古賀友紹
- Total Pages
  1
- Publisher
  日本生化学会
- Data Source
  KAKENHI-PROJECT-25860223
[Book] 疾患モデルの作製と利用「ロイコトリエンの生体内での役割」2013
- Author(s)
  古賀友紹・横溝岳彦
- Total Pages
  10
- Publisher
  株式会社　エル・アイ・シー
- Data Source
  KAKENHI-PROJECT-25860223
[Journal Article] Lactic acidosis induces metabolic and phenotypic reprogramming in cholangiocarcinoma cells via the upregulation of thrombospondin‐12023
- Author(s)
  Thamrongwaranggoon Ubonrat、Kuribayashi Kanji、Araki Hirotaka、Hino Yuko、Koga Tomoaki、Seubwai Wunchana、Wongkham Sopit、Nakao Mitsuyoshi、Hino Shinjiro
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 4 Pages: 1541-1555
- DOI
  10.1111/cas.15699
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19513, KAKENHI-PROJECT-20H04108, KAKENHI-PROJECT-20K07328, KAKENHI-PROJECT-23K18220, KAKENHI-PROJECT-20KK0185, KAKENHI-PROJECT-21H02686, KAKENHI-PROJECT-23K27381
[Journal Article] Phosphorylation of phase‐separated p62 bodies by ULK1 activates a redox‐independent stress response2023
- Author(s)
  Ikeda Ryo、Noshiro Daisuke、Morishita Hideaki、Takada Shuhei、Kageyama Shun、Fujioka Yuko、Funakoshi Tomoko、Komatsu‐Hirota Satoko、Arai Ritsuko、Ryzhii Elena、Abe Manabu、Koga Tomoaki、Motohashi Hozumi、Nakao Mitsuyoshi、Sakimura Kenji、Horii Arata、Waguri Satoshi、Ichimura Yoshinobu、Noda Nobuo N、Komatsu Masaaki
- Journal Title
  
  The EMBO Journal
  
  Volume: 42 Issue: 14
- DOI
  10.15252/embj.2022113349
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18220, KAKENHI-PROJECT-22K06300, KAKENHI-PROJECT-23K05683, KAKENHI-PROJECT-23K06415, KAKENHI-PROJECT-20KK0185, KAKENHI-ORGANIZER-19H05705, KAKENHI-PLANNED-19H05706, KAKENHI-PLANNED-19H05707, KAKENHI-ORGANIZER-21H05258, KAKENHI-PLANNED-21H05264, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-21H04771, KAKENHI-PROJECT-21H04799, KAKENHI-PROJECT-21H02686, KAKENHI-PROJECT-23K27122, KAKENHI-PROJECT-23K27134, KAKENHI-PROJECT-23K27351, KAKENHI-PROJECT-23K27381, KAKENHI-PROJECT-23H05327
[Journal Article] Loss of the transcription repressor ZHX3 induces senescence-associated gene expression and mitochondrial-nucleolar activation2022
- Author(s)
  Igata Tomoka、Tanaka Hiroshi、Etoh Kan、Hong Seonghyeon、Tani Naoki、Koga Tomoaki、Nakao Mitsuyoshi
- Journal Title
  
  PLOS ONE
  
  Volume: 17 Issue: 1 Pages: 02624880262488-02624880262488
- DOI
  10.1371/journal.pone.0262488
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15048, KAKENHI-PROJECT-21H02686, KAKENHI-PROJECT-19J00533, KAKENHI-PROJECT-20K07328, KAKENHI-PROJECT-20K16145, KAKENHI-PROJECT-20KK0185
[Journal Article] Lactic acidosis promotes aggressive features of cholangiocarcinoma cells via upregulating ALDH1A3 expression through EGFR axis2022
- Author(s)
  Thamrongwaranggoon Ubonrat、Detarya Marutpong、Seubwai Wunchana、Saengboonmee Charupong、Hino Shinjiro、Koga Tomoaki、Nakao Mitsuyoshi、Wongkham Sopit
- Journal Title
  
  Life Sciences
  
  Volume: 302 Pages: 120648-120648
- DOI
  10.1016/j.lfs.2022.120648
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19513, KAKENHI-PROJECT-20KK0185, KAKENHI-PROJECT-20H04108, KAKENHI-PROJECT-21H02686, KAKENHI-PROJECT-20K07328
[Journal Article] High glucose-ROS conditions enhance the progression in cholangiocarcinoma via upregulation of MAN2A2 and CHD82021
- Author(s)
  Thonsri U, Wongkham S, Wongkham C, Hino S, Nakao M, Roytrakul S, Koga T, Seubwai W
- Journal Title
  
  Cancer Sci.
  
  Volume: 112 Issue: 1 Pages: 254-264
- DOI
  10.1111/cas.14719
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07328, KAKENHI-PROJECT-18H02618, KAKENHI-PROJECT-20H04108, KAKENHI-PROJECT-21H02686, KAKENHI-PROJECT-20KK0185
[Journal Article] Leukotriene A4 hydrolase deficiency protects mice from diet-induced obesity by increasing energy expenditure through neuroendocrine axis.2020
- Author(s)
  Uzawa H, Kohno D, Koga T, Sasaki T, Fukunaka A, Okuno T, Jo-Watanabe A, Kazuno S, Miyatsuka T, Kitamura T, Fujitani Y, Watada H, Saeki K*, Yokomizo T
- Journal Title
  
  FASEB J
  
  Volume: 34(10) Issue: 10 Pages: 13949-13958
- DOI
  10.1096/fj.202001148r
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06923, KAKENHI-PROJECT-19K07357, KAKENHI-PROJECT-19K08971, KAKENHI-PROJECT-20K07328, KAKENHI-PROJECT-19KK0199, KAKENHI-PROJECT-18H02627, KAKENHI-PROJECT-20H03463
[Journal Article] The NSD2/WHSC1/MMSET methyltransferase prevents cellular senescence-associated epigenomic remodeling2020
- Author(s)
  Hiroshi Tanaka, Tomoka Igata, Kan Etoh, Tomoaki Koga, Shin-ichiro Takebayashi, and Mitsuyoshi Nakao.
- Journal Title
  
  Aging Cell
  
  Volume: － Issue: 7 Pages: 1-12
- DOI
  10.1111/acel.13173
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15048, KAKENHI-PROJECT-17J40011, KAKENHI-PROJECT-19K06610, KAKENHI-PROJECT-20K07328, KAKENHI-PROJECT-20K16145, KAKENHI-PROJECT-20KK0185, KAKENHI-PUBLICLY-20H05386, KAKENHI-PROJECT-18H02618, KAKENHI-PROJECT-19J00533
[Journal Article] α1-acid glycoprotein attenuates adriamycin-induced nephropathy via CD163 expressing macrophages induction2020
- Author(s)
  Fujimura Rui、Watanabe Hiroshi、Nishida Kento、Fujiwara Yukio、Koga Tomoaki、Bi Jing、Imafuku Tadashi、Kobayashi Kazuki、Komori Hisakazu、Miyahisa Masako、Maeda Hitoshi、Tanaka Motoko、Matsushita Kazutaka、Wada Takashi、Fukagawa Masafumi、Maruyama Toru
- Journal Title
  
  Kidney360
  
  Volume: ー Issue: 5 Pages: 343-353
- DOI
  10.34067/kid.0000782019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18J23070, KAKENHI-PROJECT-17K08664, KAKENHI-PROJECT-20K21485, KAKENHI-PROJECT-18H02604
[Journal Article] Expression of leukotriene B4 receptor 1 defines functionally distinct DCs that control allergic skin inflammation.2020
- Author(s)
  Tomoaki Koga, Fumiyuki Sasaki, Kazuko Saeki, Soken Tsuchiya, Toshiaki Okuno, Mai Ohba, Takako Ichiki, Satoshi Iwamoto, Hirotsugu Uzawa, Keiko Kitajima, Chikara Meno, Eri Nakamura, Norihiro Tada, Yoshinori Fukui, Junichi Kikuta, Masaru Ishii, Yukihiko Sugimoto, and Mitsuyoshi Nakao, Takehiko Yokomizo.
- Journal Title
  
  Cellular & Molecular Immunology
  
  Volume: 8 Issue: 6 Pages: 1-13
- DOI
  10.1038/s41423-020-00559-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05691, KAKENHI-PROJECT-18K06923, KAKENHI-PROJECT-18K07880, KAKENHI-PROJECT-19K07357, KAKENHI-PROJECT-19K22503, KAKENHI-PROJECT-17H01571, KAKENHI-PROJECT-17H03990, KAKENHI-PROJECT-18H02618, KAKENHI-PROJECT-18H02627, KAKENHI-PROJECT-19H00983, KAKENHI-PROJECT-21H04798, KAKENHI-PROJECT-21H02686, KAKENHI-PROJECT-20K07328, KAKENHI-PROJECT-19KK0199, KAKENHI-PROJECT-20KK0185
[Journal Article] Leukotriene B4 receptor 1 exacerbates inflammation following myocardial infarction.2020
- Author(s)
  Horii Y, Nakaya M, Ohara H, Nishihara H, Watari K, Nagasaka A, Nakaya T, Sugiura Y, Okuno T, Koga T, Tanaka A, Yokomizo T, Kurose H.
- Journal Title
  
  FASEB Journal
  
  Volume: 印刷中 Issue: 6 Pages: 8749-8763
- DOI
  10.1096/fj.202000041r
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08664, KAKENHI-PROJECT-19K07122, KAKENHI-PROJECT-19K07357, KAKENHI-PROJECT-20K07328, KAKENHI-PROJECT-19KK0199, KAKENHI-PROJECT-17H01525, KAKENHI-PROJECT-18H02627, KAKENHI-PROJECT-20H03383, KAKENHI-PROJECT-19J20083
[Journal Article] Computational analysis of morphological and molecular features in gastric cancer tissues.2020
- Author(s)
  Yasuda Y, Tokunaga K, Koga T, Goldberg I, Sakamoto C, *Saitoh N, *Nakao M
- Journal Title
  
  Cancer Med
  
  Volume: 9 Issue: 6 Pages: 2223-2234
- DOI
  10.1002/cam4.2885
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19310, KAKENHI-PROJECT-18H02618, KAKENHI-PROJECT-17K08664, KAKENHI-PROJECT-18K19479, KAKENHI-PLANNED-18H05531
[Journal Article] Cellular Senescence Variation by Metabolic and Epigenomic Remodeling.2020
- Author(s)
  Nakao M, Tanaka H, Koga T.
- Journal Title
  
  Trends Cell Biol
  
  Volume: 30 Issue: 12 Pages: 919-922
- DOI
  10.1016/j.tcb.2020.08.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07328, KAKENHI-PROJECT-20KK0185, KAKENHI-PROJECT-18H02618
[Journal Article] BLT1 mediates commensal bacteria-dependent innate immune signals to enhance antigen-specific intestinal IgA responses.2019
- Author(s)
  Nagatake T, Hirata SI, Koga T, Kuroda E, Suzuki H, Hosomi K, Matsumoto N, Yanrismet Y, Shimojou M, Morimoto S, Sasaki F, Ishii KJ, Yokomizo T, Kunisawa J.
- Journal Title
  
  Mucosal Immunology
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08664
[Journal Article] Leukotriene B4 promotes neovascularization and macrophage recruitment in murine wet-type AMD models.2018
- Author(s)
  Sasaki F., Koga T., Ohba M., Saeki K., Okuno T., Ishikawa K., Nakama T., Nakao S., Yoshida S., Ishibashi T., Ahmadieh H., Kanavi M. R., Hafezi-Moghadam A., Penninger J. M., Sonoda K. H., Yokomizo T.
- Journal Title
  
  JCI Insight
  
  Volume: 3 Issue: 18 Pages: 96902-96902
- DOI
  10.1172/jci.insight.96902
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08596, KAKENHI-PROJECT-17K08664, KAKENHI-PROJECT-18K06923, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05904, KAKENHI-PROJECT-18H02627, KAKENHI-PROJECT-15K08316
[Journal Article] Inhibition of local macrophage growth ameliorates focal inflammation and suppresses atherosclerosis.2018
- Author(s)
  Yamada S, Senokuchi T, Matsumura T, Morita Y, Ishii N, Fukuda K, Murakami S, Nishida S, Kawasaki S, Motoshima H, Furukawa N, Komohara Y, Fujiwara Y, Koga T, Yamagata K, Takeya M, Araki E
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology
  
  Volume: 印刷中 Issue: 5 Pages: 994-1006
- DOI
  10.1161/atvbaha.117.310320
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09835, KAKENHI-PROJECT-17K09863, KAKENHI-PROJECT-15K09394, KAKENHI-PROJECT-15K15348, KAKENHI-PROJECT-17K08664, KAKENHI-PROJECT-18K08482, KAKENHI-PROJECT-16H05328, KAKENHI-PROJECT-17H04060, KAKENHI-PROJECT-17H04201, KAKENHI-PROJECT-16K09247, KAKENHI-PROJECT-16K09759, KAKENHI-PROJECT-16K09787, KAKENHI-PROJECT-17K16151
[Journal Article] Profiling of bioactive lipids in different dendritic cell subsets using an improved multiplex quantitative LC-MS/MS method2018
- Author(s)
  Ohba M, Saeki K, Koga T, Okuno T, Kobayashi Y, Yokomizo T.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08664
[Journal Article] Genetic Fusion of Type-I Interferon to a Recombinant Albumin Mutant with polymannosylated N-linked oligosaccharide attached is a Novel and Superior Kupffer Cell Targeting Agent for the Treatment of Hepatitis.2018
- Author(s)
  Minayoshi Y, Maeda H, Yanagisawa H, Hamasaki K, Mizuta Y, Nishida K, Kinoshita R, Enoki Y, Imafuku T, Chuang VTG, Koga T, Fujiwara Y, Takeya M, Sonoda K, Wakayama T, Taguchi K, Ishima Y, Ishida T, Iwakiri Y, Tanaka M, Sasaki Y, Watanabe H, Otagiri M, Maruyama T.
- Journal Title
  
  Drug Delivery
  
  Volume: 25 Issue: 1 Pages: 1067-1077
- DOI
  10.1080/10717544.2018.1464083
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08664, KAKENHI-PROJECT-17K15511, KAKENHI-PROJECT-17H04060, KAKENHI-PROJECT-16K09247, KAKENHI-PROJECT-18H02587, KAKENHI-PROJECT-18H02798
[Journal Article] Profiling of bioactive lipids in different dendritic cell subsets using an improved multiplex quantitative LC-MS/MS method.2018
- Author(s)
  Ohba M., Saeki K., Koga T., Okuno T., Kobayashi Y., Yokomizo T.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 504 Issue: 3 Pages: 562-568
- DOI
  10.1016/j.bbrc.2018.06.026
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08596, KAKENHI-PROJECT-17K08664, KAKENHI-PROJECT-18K06923, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05904, KAKENHI-PROJECT-18H02627, KAKENHI-PROJECT-15K08316, KAKENHI-PROJECT-15KK0320
[Journal Article] Profiling of bioactive lipids in different dendritic cell subsets using an improved multiplex quantitative LC-MS/MS method2018
- Author(s)
  Ohba, M., Saeki, K., Koga, T., Okuno, T., Konbayashi, Y.,Yokomizo, T.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: In press
- Data Source
  KAKENHI-PROJECT-15H04708
[Journal Article] An aromatic amino acid within intracellular loop 2 of the prostaglandin EP2 receptor is a prerequisite for selective association and activation of Gαs.2017
- Author(s)
  Yano A, Takahashi Y, Moriguchi H, Inazumi T, Koga T, Otaka A, Sugimoto Y.
- Journal Title
  
  Biochim Biophys Acta Mol Cell Biol Lipids
  
  Volume: 1862 Issue: 6 Pages: 615-622
- DOI
  10.1016/j.bbalip.2017.03.006
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-15K19032, KAKENHI-PROJECT-15K18875, KAKENHI-PLANNED-15H05905, KAKENHI-PROJECT-16H02611, KAKENHI-PROJECT-17H03990, KAKENHI-PROJECT-26670030
[Journal Article] Gut microbiota promotes obesity-associated liver cancer through PGE2-mediated suppression of antitumor immunity.2017
- Author(s)
  Loo TM, Kamachi F, Watanabe Y, Yoshimoto S, Kanda H, Arai Y, Nakajima-Takagi Y, Iwama A, Koga T, Sugimoto Y, Ozawa T, Nakamura M, Kumagai M, Watashi K, Taketo M, Aoki T, Narumiya S, Oshima M, Arita M, Hara E, Ohtani N.
- Journal Title
  
  Cancer Discov
  
  Volume: in press Issue: 5 Pages: 522-538
- DOI
  10.1158/2159-8290.cd-16-0932
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PLANNED-15H05905, KAKENHI-PROJECT-26250028, KAKENHI-PROJECT-14J06998, KAKENHI-PROJECT-15K12709, KAKENHI-PROJECT-15K19032, KAKENHI-PROJECT-26670030, KAKENHI-PROJECT-15K19031, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17H01531, KAKENHI-PROJECT-15H04648, KAKENHI-PROJECT-17H03990, KAKENHI-PROJECT-26460565, KAKENHI-PROJECT-16H04699
[Journal Article] Inhibition of Leukotriene B4 Action Mitigates Intracerebral Hemorrhage-Associated Pathological Events in Mice2017
- Author(s)
  Hijioka, M., Anan, J., Ishibashi, H., Kurauchi, Y., Hisatsune, A., Seki, T., Koga, T., Yokomizo, T., Shimizu, T.,Katsuki, H.
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 360 Issue: 3 Pages: 399-408
- DOI
  10.1124/jpet.116.238824
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05904, KAKENHI-PROJECT-15H04708, KAKENHI-PROJECT-16H04673, KAKENHI-PROJECT-15K18865, KAKENHI-PROJECT-15K19032, KAKENHI-PROJECT-16K08276, KAKENHI-PROJECT-16K15204
[Journal Article] Mild electrical stimulation with heat shock guides differentiation of embryonic stem cells into Pdx1-expressing cells within the definitive endoderm.2017
- Author(s)
  Koga T, Shiraki N, Yano S, Suico MA, Morino-Koga S, Sato T, Shuto T, Kume S, Kai H
- Journal Title
  
  BMC Biotechnology
  
  Volume: 17 Issue: 1 Pages: 14-14
- DOI
  10.1186/s12896-017-0331-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461638, KAKENHI-PROJECT-15K12514, KAKENHI-PROJECT-15K19032, KAKENHI-PROJECT-16K01362, KAKENHI-PROJECT-16K18875
[Journal Article] Dioxin-induced increase in leukotriene B4 biosynthesis through the aryl hydrocarbon receptor and its relevance to hepatotoxicity owing to neutrophil infiltration2017
- Author(s)
  Takeda Tomoki、Komiya Yukiko、Koga Takayuki、Ishida Takumi、Ishii Yuji、Kikuta Yasushi、Nakaya Michio、Kurose Hitoshi、Yokomizo Takehiko、Shimizu Takao、Uchi Hiroshi、Furue Masutaka、Yamada Hideyuki
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 292 Issue: 25 Pages: 10586-10599
- DOI
  10.1074/jbc.m116.764332
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05904, KAKENHI-PUBLICLY-17H05510, KAKENHI-PROJECT-17H01525, KAKENHI-PROJECT-15H04708, KAKENHI-PROJECT-17H03984
[Journal Article] Non-steroidal anti-inflammatory drug delays corneal wound healing by reducing production of 12-hydroxyheptadecatrienoic acid, a ligand for leukotriene B4 receptor 22017
- Author(s)
  Iwamoto Satoshi、Koga Tomoaki、Ohba Mai、Okuno Toshiaki、Koike Masato、Murakami Akira、Matsuda Akira、Yokomizo Takehiko
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 13267-13267
- DOI
  10.1038/s41598-017-13122-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08596, KAKENHI-PROJECT-17K08522, KAKENHI-PROJECT-16K20334, KAKENHI-PROJECT-15KK0320, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05904, KAKENHI-PROJECT-15H04708
[Journal Article] Generation and characterization of a human-mouse chimeric high-affinity antibody that detects the DYKDDDDK FLAG peptide2017
- Author(s)
  Ikeda K, Koga T, Sasaki F, Ueno A, Saeki K, Okuno T, Yokomizo T.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 486 Issue: 4 Pages: 1077-1082
- DOI
  10.1016/j.bbrc.2017.03.165
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K19032, KAKENHI-PROJECT-15K08316, KAKENHI-PROJECT-16K08596, KAKENHI-PROJECT-15KK0320, KAKENHI-PLANNED-15H05904
[Journal Article] Biochemical and immunological characterization of a novel monoclonal antibody against mouse leukotriene B4 receptor 1.2017
- Author(s)
  Sasaki F, Koga T, Saeki K, Okuno T, Kazuno S, Fujimura T, Ohkawa Y, Yokomizo T
- Journal Title
  
  PLoS One
  
  Volume: 12 Issue: 9 Pages: 0185133-0185133
- DOI
  10.1371/journal.pone.0185133
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08316, KAKENHI-PROJECT-16K08596, KAKENHI-PROJECT-17K00874, KAKENHI-PROJECT-17K19356, KAKENHI-PROJECT-15KK0320, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05904, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-15H04708, KAKENHI-PROJECT-17H03608
[Journal Article] Receptor for Advanced Glycation End Products Regulates Leukotriene B4 Receptor 1 Signaling2016
- Author(s)
  Ichiki, T., Koga, T.,Yokomizo, T.
- Journal Title
  
  DNA Cell Biol
  
  Volume: 35 Issue: 12 Pages: 747-750
- DOI
  10.1089/dna.2016.3552
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05904, KAKENHI-PROJECT-15H04708, KAKENHI-PROJECT-15K19032
[Journal Article] Modulation of leukotriene B4 receptor 1 signaling by receptor for advanced glycation end products, RAGE.2016
- Author(s)
  Ichiki T, Koga T, Okuno T, Saeki K, Yamamoto Y, Yamamoto H, Sakaguchi M, Yokomizo T
- Journal Title
  
  FASEB J
  
  Volume: 30 Issue: 5 Pages: 1811-1822
- DOI
  10.1096/fj.201500117
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19032, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05904, KAKENHI-ORGANIZER-22116001, KAKENHI-PROJECT-15H04708, KAKENHI-PROJECT-13J02797, KAKENHI-PROJECT-25460374, KAKENHI-PROJECT-26293352, KAKENHI-PROJECT-15K08316, KAKENHI-PROJECT-16K08596, KAKENHI-PROJECT-15KK0320
[Journal Article] Leukotriene B4 receptor type 2 protects against pneumolysin-dependent acute lung injury2016
- Author(s)
  Shigematsu, M., Koga, T., Ishimori, A., Saeki, K., Ishii, Y., Taketomi, Y., Ohba, M., Jo-Watanabe, A., Okuno, T., Harada, N., Harayama, T., Shindou, H., Li, J. D., Murakami, M., Hoka, S.,Yokomizo, T.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 34560-34560
- DOI
  10.1038/srep34560
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05904, KAKENHI-PROJECT-24229003, KAKENHI-PROJECT-16H02613, KAKENHI-PROJECT-15H04708, KAKENHI-PROJECT-15H06604, KAKENHI-PROJECT-26460380, KAKENHI-PROJECT-15K19032, KAKENHI-PROJECT-15K08316, KAKENHI-PROJECT-16K08596, KAKENHI-PROJECT-16K09587, KAKENHI-PROJECT-16K15122, KAKENHI-PROJECT-15KK0320, KAKENHI-PROJECT-15J12316
[Journal Article] Leukotriene B4 receptor type 2 (BLT2) enhances skin barrier function by regulating tight junction proteins.2016
- Author(s)
  Ishii Y, Saeki K, Liu M, Sasaki F, Koga T, Kitajima K, Meno C, Okuno T, Yokomizo T
- Journal Title
  
  FASEB J
  
  Volume: 30 Issue: 2 Pages: 933-947
- DOI
  10.1096/fj.15-279653
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K08316, KAKENHI-PROJECT-26461637, KAKENHI-PROJECT-15K19032, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05904, KAKENHI-ORGANIZER-22116001, KAKENHI-PROJECT-15H04708, KAKENHI-PROJECT-25460374, KAKENHI-PROJECT-26291051, KAKENHI-PROJECT-16K08596, KAKENHI-PROJECT-15KK0320
[Journal Article] Podocyte p53 limits the severity of experimental Alport syndrome.2015
- Author(s)
  Fukuda R., et al.
- Journal Title
  
  Jounal of American Society of Nephrology
  
  Volume: just accepted Issue: 1 Pages: 144-157
- DOI
  10.1681/asn.2014111109
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25860223, KAKENHI-PROJECT-26460098, KAKENHI-PROJECT-15K12514, KAKENHI-PROJECT-15K19032, KAKENHI-PROJECT-25460102
[Journal Article] Endoplasmic Reticulum (ER) Stress Induces Sirtuin 1 (SIRT1) Expression via the PI3K-Akt-GSK3β Signaling Pathway and Promotes Hepatocellular Injury.2015
- Author(s)
  Koga T, Suico MA, Shimasaki S, Watanabe E, Kai Y, Koyama K, Omachi K, Morino-Koga S, Sato T, Shuto T, Mori K, Hino S, Nakao M, Kai H.
- Journal Title
  
  J Biol Chem.
  
  Volume: 290 Issue: 51 Pages: 30366-30374
- DOI
  10.1074/jbc.m115.664169
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460098, KAKENHI-PROJECT-15K19032, KAKENHI-PROJECT-25253012, KAKENHI-PROJECT-25430178, KAKENHI-PROJECT-25460102
[Journal Article] Suppression of inflammation viaPDE4B-JNK2-dependent upregulation of deubiquitinase CYLD2013
- Author(s)
  Komatsu K, Lee J, Miyata M, Lim JH, Jono H, Koga T, Xu H, Yan C, Kai H, Li JD
- Journal Title
  
  Nature Commun
  
  Volume: 4
- Data Source
  KAKENHI-PROJECT-23890146
[Journal Article] Insulin receptor activation through its accumulation in lipid rafts by mild electrical stress2013
- Author(s)
  Morino-Koga S, Yano S, Kondo T, Shimauchi Y, Matsuyama S, Okamoto Y, Suico MA, Koga T, Sato T, Shuto T, Arima H, Wada I, Araki E, Kai H
- Journal Title
  
  J Cell Physiol
  
  Volume: 228(2) Pages: 439-446
- Data Source
  KAKENHI-PROJECT-23890146
[Journal Article] Mild electrical stimulation and heat shock ameliorates progressive proteinuria and renal inflammation in mouse model of Alport syndrome.2012
- Author(s)
  Tomoaki Koga
- Journal Title
  
  PLoS One
  
  Volume: 7 Issue: 8 Pages: 43852-43852
- DOI
  10.1371/journal.pone.0043852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390015, KAKENHI-PROJECT-23590082, KAKENHI-PROJECT-23650269, KAKENHI-PROJECT-23890146, KAKENHI-PROJECT-24790079
[Journal Article] Mild electrical stimulation and heat shock ameliorates progressive proteinuria and renal inflammation in mouse model of Alport syndrome2012
- Author(s)
  Koga T, Kai Y, Fukuda R, Morino-Koga S, Suico MA, Koyama K, Sato T, Shuto T, Kai H
- Journal Title
  
  PLoS ONE
  
  Volume: 7(8)
- Data Source
  KAKENHI-PROJECT-23890146
[Journal Article]2012
- Author(s)
  Lim JH, Jono H, Komatsu K, Woo CH, Lee J, Miyata M, Matsuno T, Xu X, Huang Y, Zhang W, Park SH, Kim YI, Choi YD, Shen H, Heo KS, Xu H, Bourne P, Koga T, Xu H, Yan C, Wang B, Chen LF, Feng XH, Li JD.
- Journal Title
  
  Nature Commun
- Data Source
  KAKENHI-PROJECT-23890146
[Journal Article] STT3B-dependent posttranslational N- glycosylation as a sruceillance system for secretory protein2012
- Author(s)
  Sato T, Sako Y, Sho M, Momohara M, Suico MA, Shuto T, Nishitoh H, Okiyoneda T, Kokame K, Kaneko M, Taura M, Miyata M, Chosa K, Koga T, Morino-Koga S, Wada I, Kai H
- Journal Title
  
  Mol Cell
  
  Volume: 47(1) Pages: 99-110
- Data Source
  KAKENHI-PROJECT-23890146
[Journal Article] Insulin receptor activation through its accumulation in lipid rafts by mild electrical stress2012
- Author(s)
  Morino-Koga S
- Journal Title
  
  J Cell Physiol.
  
  Volume: 228 Issue: 2 Pages: 439-446
- DOI
  10.1002/jcp.24149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390015, KAKENHI-PROJECT-23390243, KAKENHI-PROJECT-23650269, KAKENHI-PROJECT-23890146, KAKENHI-PROJECT-24591336, KAKENHI-PROJECT-24790079
[Journal Article] Lucidenic acids-rich extract from antlered form of Ganoderma lucidum enhances TNF-alpha induction in THP-1 monocytic cells possibly via its modulation of MAP kinases p38 and JNK.2011
- Author(s)
  Watanabe K, Shuto T, Sato M, Onuki K, Mizunoe S, Suzuki S, Sato T, Koga T, Suico MA, Kai H, Ikeda T.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 408(1) Pages: 18-24
- Data Source
  KAKENHI-PROJECT-23890146
[Presentation] 骨髄球系細胞における炎症応答のエピゲノム制御機構2024
- Author(s)
  古賀友紹
- Organizer
  発生研ミニシンポジウム”酵母と哺乳類におけるエピジェネティック制御”
- Data Source
  KAKENHI-PROJECT-23K18220
[Presentation] 時間依存的トランスクリプトーム解析が解き明かす自然免疫記憶における脂質代謝の意義2024
- Author(s)
  洪性賢、古賀友紹、船藏直史、中尾光善
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K18220
[Presentation] リジン特異的脱メチル化酵素Kdm7aはM1/M2マクロファージ均衡を制御する2024
- Author(s)
  船藏直史、古賀友紹、洪性賢、衛藤貫、井上俊洋、中尾光善
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K18220
[Presentation] 骨髄球系細胞における炎症応答のエピゲノム制御機構2024
- Author(s)
  古賀友紹
- Organizer
  発生研ミニシンポジウム”酵母と哺乳類におけるエピジェネティック制御”
- Data Source
  KAKENHI-PROJECT-23K27381
[Presentation] 時間依存的トランスクリプトーム解析が解き明かす自然免疫記憶における脂質代謝の意義2023
- Author(s)
  洪性賢、古賀友紹、船藏直史、中尾光善
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K27381
[Presentation] リジン特異的脱メチル化酵素KDM7Aによる肺線維症のエピゲノム制御機構の解明2023
- Author(s)
  古賀友紹、中尾光善
- Organizer
  日本薬学会第１４３回年会
- Data Source
  KAKENHI-PROJECT-20K07328
[Presentation] リジン特異的脱メチル化酵素Kdm7aはM1/M2マクロファージ均衡を制御する2023
- Author(s)
  船藏直史、古賀友紹、洪性賢、衛藤貫、井上俊洋、中尾光善
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K27381
[Presentation] ロイコトリエンB4受容体BLT1で規定される炎症性樹状細胞のエピゲノム制御機構2023
- Author(s)
  古賀友紹、横溝岳彦、中尾光善
- Organizer
  日本薬学会第１４３回年会
- Data Source
  KAKENHI-PROJECT-20K07328
[Presentation] Leukotriene B4 receptor 1 defines functionally and epigenetically distinct DCs that control allergic skin inflammation.2022
- Author(s)
  Koga T, Sasaki F, Saeki K, Tsuchiya S, Okuno T, Fukui, Y, Kikuta J, Ishii M, Sugimoto Y, Yokomizo T, Nakao M.
- Organizer
  第５１回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07328
[Presentation] リジン特異的脱メチル化酵素KDM7AはM2マクロファージ極性化を抑制する2022
- Author(s)
  船藏直史、古賀友紹、中尾光善
- Organizer
  第４５回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K07328
[Presentation] Expression of leukotriene B4 receptor 1 defines functionally and epigenetically distinct DCs that control allergic skin inflammation.2022
- Author(s)
  Koga T, Sasaki F, Saeki K, Tsuchiya S, Okuno T, Sugimoto Y, Yokomizo T, Nakao M.
- Organizer
  Bioactive Lipids in Cancer, Inflammation and Related Diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07328
[Presentation] マクロファージにおける内毒素による自然免疫記憶の解明2022
- Author(s)
  洪性賢、古賀友紹、中尾光善
- Organizer
  第４５回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K07328
[Presentation] Epigenetic regulation of inflammatory dendritic cells2022
- Author(s)
  Koga T, Hong S, Yokomizo T, Nakao M.
- Organizer
  Keystone meeting for Innate Immune Memory: from evolutionary roots to human disease, X3.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07328
[Presentation] エピゲノム修飾酵素による肺線維症のエピゲノム制御2022
- Author(s)
  古賀友紹、船藏直史、洪性賢、中尾光善
- Organizer
  フォーラム2022 衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PROJECT-20K07328
[Presentation] M2マクロファージの極性化に関わるエピゲノム制御機構の解明2022
- Author(s)
  古賀友紹、船藏直史、洪性賢、中尾光善
- Organizer
  第１５回日本エピジェネティクス研究会年会
- Data Source
  KAKENHI-PROJECT-20K07328
[Presentation] ヒストン脱メチル化酵素KDM7Aによるマクロファージの極性化制御機構2021
- Author(s)
  古賀友紹、洪性賢、井形朋香、衛藤貫、日野信次朗、中尾光善
- Organizer
  第14回日本エピジェネティクス研究会年会
- Data Source
  KAKENHI-PROJECT-20KK0185
[Presentation] ロイコトリエンB4受容体で規定される炎症性樹状細胞の機能解析2021
- Author(s)
  古賀友紹、横溝岳彦、中尾光善
- Organizer
  2021年東京呼吸器リサーチフォーラム
- Data Source
  KAKENHI-PROJECT-20K07328
[Presentation] 脂質とエピゲノムによる炎症性単球系サブセットの機能制御2021
- Author(s)
  古賀友紹、中尾光善
- Organizer
  第42回日本基礎老化学会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20K07328
[Presentation] ヒストン脱メチル化酵素KDM7Aによるマクロファージの極性化制御機構2021
- Author(s)
  古賀友紹、洪性賢、中尾光善
- Organizer
  第14回日本エピジェネティクス研究会年会
- Data Source
  KAKENHI-PROJECT-20K07328
[Presentation] Epigenome reprogramming of M2 type macrophages by histone demethylase2020
- Author(s)
  Tomoaki Koga、Seong Hyeon Hong、Mitsuyoshi Nakao
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K07328
[Presentation] ロイコトリエンB4とその受容体BLT1による樹状細胞の機能制御2020
- Author(s)
  古賀友紹、佐々木文之、横溝岳彦、中尾光善
- Organizer
  第43回日本分子生物学会年会　フォーラム「脂質多様性を基軸とした炎症・免疫制御」
- Data Source
  KAKENHI-PROJECT-20K07328
[Presentation] 脂質メディエーターとエピゲノムによる単球系サブセットの制御機構2019
- Author(s)
  古賀友紹、横溝岳彦、中尾光善
- Organizer
  第13回日本エピジェネティクス研究会年会　2019年5月28日～29日　横浜
- Data Source
  KAKENHI-PROJECT-17K08664
[Presentation] 炎症・免疫細胞サブセットにおけるエピゲノム因子の機能解析2019
- Author(s)
  古賀友紹、横溝岳彦、中尾光善
- Organizer
  第43回蛋白質と酵素の構造と機能に関する九州シンポジウム　2019年9月5日～7日　福岡
- Data Source
  KAKENHI-PROJECT-17K08664
[Presentation] Regulation of Monocytic cell subset by Lipid mediator and Epigenome2019
- Author(s)
  Tomoaki Koga、Fumiyuki Sasaki、Takehiko Yokomizo、Mitsuyoshi Nakao
- Organizer
  第42回日本分子生物学会年会　2019年12月5日　福岡
- Data Source
  KAKENHI-PROJECT-17K08664
[Presentation] 生理活性脂質 LTB4 及びその受容体 BLT1 による新規樹状細胞サブセット制御機構2018
- Author(s)
  古賀友紹, 佐々木文之, 佐伯和子, 奥野利明, 中尾光善, 横溝岳彦.
- Organizer
  第15回　東京呼吸器リサーチフォーラム
- Data Source
  KAKENHI-PROJECT-17K08664
[Presentation] ロイコトリエンB4第一受容体により規定される新規樹状細胞サブセットの同定2018
- Author(s)
  古賀友紹、中尾光善、横溝岳彦
- Organizer
  第12回　日本エピジェネティクス研究会年会
- Data Source
  KAKENHI-PROJECT-17K08664
[Presentation] ロイコトリエンB4第一受容体BLT1による免疫活性化機構の解析2017
- Author(s)
  古賀友紹、佐々木文之、佐伯和子、奥野利明、中尾光善、横溝岳彦
- Organizer
  2017年度生命科学系学会合同年次大会(ConBio2017)
- Data Source
  KAKENHI-PROJECT-15H04708
[Presentation] Protective roles of 12-hydroxyheptadecatrienoic acid/BLT2 in acute lung injury2017
- Author(s)
  Shigematsu, M, Koga, T, Saeki, K, Ohba, M, Okuno, T and Yokomizo, T
- Organizer
  Keystone Symposium, Lipidomics and Bioactive Lipids in Metabolism and Disease
- Place of Presentation
  Tahoe
- Year and Date
  2017-02-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04708
[Presentation] A fatty acid 12-hydroxyheptadecatrienoic acid accelerates corneal wound healing through leukotriene B4 receptor 2, BLT22017
- Author(s)
  Yokomizo、 T.、 Iwamoto、 S.、 Koga、 T.、 Ohba、 M.、 Okuno、 T.、 Koike、 M.、 Murakami、 A.、Matsuda、 A.
- Organizer
  Keystone Symposium, GPCR Structure and Function
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04708
[Presentation] 生理活性脂質ロイコトリエンB4とその受容体BLT1による免疫制御機構の解析2017
- Author(s)
  古賀友紹、中尾光善、横溝岳彦
- Organizer
  第41回蛋白質と酵素の構造と機能に関する九州シンポジウム
- Data Source
  KAKENHI-PROJECT-17K08664
[Presentation] 生理活性脂質ロイコトリエンB4とその受容体BLT1による生体防御応答2017
- Author(s)
  古賀友紹、中尾光善、横溝岳彦
- Organizer
  第７回オルソオルガノジェネシス検討会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08664
[Presentation] ロイコトリエンA4水解酵素の代謝における解析2017
- Author(s)
  鵜澤博嗣、古賀友紹、佐伯和子、宮塚健、綿田裕孝、横溝岳彦
- Organizer
  2017年度生命科学系学会合同年次大会(ConBio2017)
- Data Source
  KAKENHI-PROJECT-15H04708
[Presentation] 12-HHT/BLT2 axis protects against pneumolysin-dependent acute lung injury2017
- Author(s)
  Saeki、 K.、 Shigematsu、 M.、 Koga、 T.、 Ohba、 M.、 Okuno、 T.、Yokomizo、 T.
- Organizer
  Keystone Symposium、 Integrating Metabolism and Immunity
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04708
[Presentation] The roles of 12-hydroxyheptadecatrienoic acid/BLT2 axis in skin2016
- Author(s)
  Shigematsu, M, Koga, T, Saeki, K, Okuno, T and Yokomizo, T
- Organizer
  57th ICBL, International Conference on the Bioscience of Lipids
- Place of Presentation
  Chamonix-Mont-Blanc, France
- Year and Date
  2016-09-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04708
[Presentation] Generation of chimeric high-affinity monoclonal antibody for FLAG tag2016
- Author(s)
  Ikeda, K, Sasaki, F, Ueno, A, Okuno, T, Koga, T and Yokomizo, T
- Organizer
  ASBMB meeting
- Place of Presentation
  San Diego
- Year and Date
  2016-04-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04708
[Presentation] Receptor for advanced glycation endproducts modulates leukotriene B4 receptor 1 signaling2016
- Author(s)
  Ichiki, T, Koga, T, Okuno, T, Saeki, K, Yamamoto, Y, Sakaguchi, M and Yokomizo, T
- Organizer
  ASBMB meeting
- Place of Presentation
  San Diego
- Year and Date
  2016-04-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04708
[Presentation] Expression and Function of Leukotriene B4 receptor 1 in dendritic cells2016
- Author(s)
  Tomoaki Koga, Fumiyuki Sasaki, Kazuko Saeki, Takako Ichiki, Toshiaki Okuno, Takehiko Yokomizo
- Organizer
  Environment Controlling normal and diseased hematopoietic and immune systems
- Place of Presentation
  横浜
- Year and Date
  2016-03-02
- Data Source
  KAKENHI-PROJECT-15K19032
[Presentation] RAGEはロイコトリエンB4第一受容体BLT1と機能的に相互作用する2016
- Author(s)
  市木貴子, 古賀友紹, 奥野利明, 佐伯和子, 阪口政清, 山本靖彦、横溝岳彦
- Organizer
  第89回日本生化学会
- Place of Presentation
  仙台
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15H04708
[Presentation] CRISPR/Cas9を用いたLeukotriene A4 hydrolase 欠損マウスの作製2016
- Author(s)
  古賀友紹、奥野利明、佐伯和子、横溝岳彦
- Organizer
  第40回タンパク質と酵素の機能に関する九州シンポジウム
- Place of Presentation
  指宿ベイテラス
- Year and Date
  2016-08-26
- Data Source
  KAKENHI-PROJECT-15K19032
[Presentation] BLT2 receptor protects against lethal acute lung injury induced by a pneumococcal toxin pneumolysin2016
- Author(s)
  Shigematsu, M, Koga, T, Saeki, K, Okuno, T and Yokomizo, T
- Organizer
  ASBMB meeting
- Place of Presentation
  San Diego
- Year and Date
  2016-04-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04708
[Presentation] CRISPR/Cas9によるロイコトリエンA4水解酵素欠損マウスの作製2015
- Author(s)
  古賀友紹, 奥野利明, 佐伯和子, 中村衣里, 多田昇弘, 横溝岳彦
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K19032
[Presentation] 新規樹状細胞サブセットマーカー分子としてのロイコトリエンB4受容体2014
- Author(s)
  古賀友紹
- Organizer
  第35回日本炎症・再生医学会／第1回日本骨免疫会議
- Place of Presentation
  沖縄
- Invited
- Data Source
  KAKENHI-PROJECT-25860223
[Presentation] 新規樹状細胞サブセットマーカー分子としてのロイコトリエンB4受容体2014
- Author(s)
  古賀友紹
- Organizer
  第１３４回日本薬学会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25860223
[Presentation] 新規樹状細胞サブセットマーカーとしてのBLT1受容体2013
- Author(s)
  古賀友紹
- Organizer
  第５５回日本脂質生化学会
- Place of Presentation
  松島
- Data Source
  KAKENHI-PROJECT-25860223
[Presentation] Role of leukotriene B4 receptor BLT1 in dendritic cells2013
- Author(s)
  Koga T. et al.
- Organizer
  Faseb SRC:Lysophospholipid and Other Related Mediators-From Bench to Clinic.
- Place of Presentation
  ニセコ
- Data Source
  KAKENHI-PROJECT-25860223
[Presentation] Leukotriene B4 receptor 1 is a potential marker of mouse dendritic cells2013
- Author(s)
  Koga T. et al.
- Organizer
  The 8th Korea-Japan Conference on Cellular Signaling for Young Scientists
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-25860223
[Presentation] BLT1 defines a DC1 subset that induces Th1 differentiation by releasing IL-12p35.2013
- Author(s)
  Koga T. et al.
- Organizer
  第４２回日本免疫学会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-25860223
[Presentation] BLT1 as a potential marker of mouse dendritic cell subsets.2012
- Author(s)
  古賀友紹
- Organizer
  第41回日本免疫学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23890146
[Presentation] A novel dendritic cell subset that promotes Th17 differentiation.2012
- Author(s)
  Koga T, et al.
- Organizer
  12th Biennial International Endotoxin & Innate Immunity Society (IEIIS) Meeting
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-23890146
[Presentation] BLT1 as a potential marker of mouse dendritic cell subsets2011
- Author(s)
  Koga T, et al
- Organizer
  The 10^<th> JBS Biofrontier Symposium : New aspects of phospholipid biology and medicine
- Place of Presentation
  Fukuoka
- Data Source
  KAKENHI-PROJECT-23890146
[Presentation] Distinct roles of BLT1hi DCs and BLT1lo DCs in activating T cells.
- Author(s)
  Koga T., et al.
- Organizer
  Keystone Symposium-macrophages and dendritic cells reunited-
- Place of Presentation
  Motreal, Canada
- Year and Date
  2015-03-08 – 2015-03-13
- Data Source
  KAKENHI-PROJECT-25860223
[Presentation] BLT1 defines dendritic cell subsets with different characteristics in differentiation and proliferation of T cells.
- Author(s)
  Koga T., et al.
- Organizer
  the 6th international conference on phospholipase A2 and lipid mediators
- Place of Presentation
  Keio Plaza Hotel, Tokyo
- Year and Date
  2015-02-10 – 2015-02-12
- Data Source
  KAKENHI-PROJECT-25860223
[Presentation] 新規樹状細胞サブセットマーカー分子としてのロイコトリエンB4受容体
- Author(s)
  古賀友紹
- Organizer
  第35回日本炎症・再生医学会
- Place of Presentation
  万国津梁館、沖縄
- Year and Date
  2014-07-01 – 2014-07-04
- Invited
- Data Source
  KAKENHI-PROJECT-25860223
[Presentation] ロイコトリエンB4第一受容体BLT1陽性樹状細胞はTh1分化誘導を促進する
- Author(s)
  古賀友紹
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都国際会議場、京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25860223

1. Yokomizo Takehiko (60302840)

# of Collaborated Projects: 2 results

# of Collaborated Products: 23 results
2. Saeki Kazuko (00553273)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
3. Okuno Toshiaki (60361466)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
4. NAKAO MITSUYOSHI (00217663)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 長岡克弥 (00759524)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 藤巻慎 (10795678)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 幸脇貴久 (90780784)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 甲斐広文 (30194658)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 斉藤貴志 (90360552)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SENOKUCHI Takafumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. SHIRAKI Nobuaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. HINO Shinjiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
13. 井形朋香

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. 松村剛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 石井規夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 杉本幸彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. 有田誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 有田正規

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 岡村孝司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 多田昇弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 斉藤典子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. メリー・アンスイコ

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Koga Tomoaki 古賀 友紹

KOGA Tomoaki 古賀 友紹

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Co-Researchers

生体防御システムにおける骨格筋の新たな役割

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Development of novel therapeutic strategies of chronic inflammatory diseases by using inflammatory memory cell visualizing mousePrincipal Investigator

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シン・マルチエピゲノム解析を基盤とした免疫細胞の多階層オミクス解析Principal Investigator

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Elucidation of Epigenome network for regulating inflammation memoryPrincipal Investigator

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Analysis of epigenome and metabolic phenotypes in Thai liver fluke-associated cholangiocarcinoma

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Biochemical elucidation of LTA4 hydrolase in immune cellsPrincipal Investigator

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Elucidation of leukotriene B4 receptor 1, BLT1-dependent immune response by dendritic cells and neutrophilsPrincipal Investigator

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The roles of receptors for lipid mediators in inflammation, immunity and barrier function

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Elucidation of novel DC subset defined by expression of BLT1Principal Investigator

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The role of Leukotrine B4 in dendritic cell-T cell interactionPrincipal Investigator

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[Book] 臨床免疫・アレルギー科 第70巻 ロイコトリエンB4とその受容体による免疫調節機構2018

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[Book] 医学のあゆみ256巻5号 GPCR研究の最前線2016「ロイコトリエン受容体」2016

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[Book] 「疾患モデルの作製と利用―脂質代謝異常と関連疾患」下巻 第5章 脂質メディエーター、第4節 ロイコトリエン2015

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Koga Tomoaki 古賀友紹

KOGA Tomoaki 古賀友紹

[Book] 臨床免疫・アレルギー科　第70巻ロイコトリエンB4とその受容体による免疫調節機構2018

[Book] 医学のあゆみ256巻5号　GPCR研究の最前線2016「ロイコトリエン受容体」2016

[Book] 「疾患モデルの作製と利用―脂質代謝異常と関連疾患」下巻　第5章　脂質メディエーター、第4節　ロイコトリエン2015