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Mizutani Anna  水谷 アンナ

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MIZUTANI ANNA  水谷 アンナ

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Researcher Number 30615159
Other IDs
Affiliation (based on the past Project Information) *help 2019: 公益財団法人がん研究会, がん化学療法センター 分子生物治療研究部, 特任研究員
2017 – 2018: 公益財団法人がん研究会, がん化学療法センター 分子生物治療研究部, 研究員
2015: 公益財団法人がん研究会, がん化学療法センター分子生物治療研究部, 研究員
2014: 公益財団法人がん研究会, その他部局等, 研究員
2013: 東京大学, 医学(系)研究科(研究院), 特任研究員
2012 – 2013: 東京大学, 医学(系)研究科(研究院), 研究員
Review Section/Research Field
Principal Investigator
Tumor biology / Tumor biology
Keywords
Principal Investigator
ポリADPリボシル化 / 翻訳後修飾 / タンキラーゼ / マイクロRNA生合成 / がん / ポリ(ADP-リボシル)化 / miRNA / ユビキチンリガーゼ / スプライシング制御 / タンパク質機能制御 … More / ユビキチン化 / 明細胞型腎細胞がん / スプライシング / 癌幹細胞 / 乳がん / がん幹細胞 Less
  • Research Projects

    (3 results)
  • Research Products

    (14 results)
  • Co-Researchers

    (4 People)
  •  Elucidation of integrative regulation mechanisms for tankyrase-mediated miRNA biosynthesis in cancerPrincipal Investigator

    • Principal Investigator
      Mizutani Anna
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor biology
    • Research Institution
      Japanese Foundation for Cancer Research
  •  Regulation of tumor-specific alternative splicingPrincipal Investigator

    • Principal Investigator
      MIZUTANI Anna
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Tumor biology
    • Research Institution
      Japanese Foundation for Cancer Research
  •  Regulation of EGF signaling transduction in breast cancer-initiating cells and their nichesPrincipal Investigator

    • Principal Investigator
      MIZUTANI ANNA
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Tumor biology
    • Research Institution
      The University of Tokyo

All 2020 2018 2016 2015 2013 Other

All Journal Article Presentation

  • [Journal Article] Tankyrase promotes primary precursor miRNA processing to precursor miRNA.2020

    • Author(s)
      Mizutani A, Seimiya H.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 52 Issue: 4 Pages: 945-951

    • DOI

      10.1016/j.bbrc.2019.11.191

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-18H04633, KAKENHI-PROJECT-19H03523, KAKENHI-PROJECT-17K07186, KAKENHI-PROJECT-16H06276
  • [Journal Article] RK-287107, a potent and specific tankyrase inhibitor, blocks colorectal cancer cell growth in a preclinical model.2018

    • Author(s)
      Mizutani A, Yashiroda Y, Muramatsu Y, Yoshisa H, Chikada T, Tsumura T, Okue M, Shirai F, Fukami T, Yoshida M, Seimiya H.
    • Journal Title

      Cancer Science

      Volume: 109 Issue: 12 Pages: 4003-4014

    • DOI

      10.1111/cas.13805

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07186, KAKENHI-PLANNED-18H05503, KAKENHI-PUBLICLY-18H04633, KAKENHI-PROJECT-16H04716, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-26221204
  • [Journal Article] The Arkadia-ESRP2 axis suppresses tumor progression: analyses in clear-cell renal cell carcinoma2016

    • Author(s)
      Mizutani A, Koinuma D, Seimiya H, Miyazono K.
    • Journal Title

      Oncogene

      Volume: - Issue: 27 Pages: 3514-3523

    • DOI

      10.1038/onc.2015.412

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22112002, KAKENHI-ORGANIZER-22112001, KAKENHI-PROJECT-26830066, KAKENHI-PROJECT-15H05774
  • [Journal Article] An adaptor protein complex of FRS2beta and CIN85/CD2AP provides a novel mechanism for ErbB2/HER2 protein downregulation2013

    • Author(s)
      後藤 典子
    • Journal Title

      Cancer Sci

      Volume: 104 Issue: 3 Pages: 345-352

    • DOI

      10.1111/cas.12086

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-22130009, KAKENHI-PROJECT-23390087, KAKENHI-PROJECT-23510261, KAKENHI-PROJECT-23659192, KAKENHI-PROJECT-23659626, KAKENHI-PUBLICLY-24121705, KAKENHI-PROJECT-24700968, KAKENHI-PROJECT-25460357
  • [Presentation] RK-287107, a potent and specific tankyrase inhibitor, blocks colorectal cancer cell growth in a preclinical model2018

    • Author(s)
      Anna Mizutani, Yukiko Muramatsu, Haruka Yoshida, Hiroyuki Seimiya
    • Organizer
      The 77th Annual Meeting of the Japanese Cancer Association
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07186
  • [Presentation] The Arladia-ESRP2 axis suppresses tumor progression: analyses in clear-cell renal cell carcinoma2015

    • Author(s)
      Anna Mizutani, Daizo Koinuma, Hiroyuki Seimiya, Kohei Miyazono
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋(愛知県)
    • Year and Date
      2015-10-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26830066
  • [Presentation] The Arladia-ESRP2 axis suppresses tumor progression: analyses in clear-cell renal cell carcinoma2015

    • Author(s)
      Anna Mizutani, Daizo Koinuma, Hiroyuki Seimiya, Kohei Miyazono
    • Organizer
      American Association for Cancer Research Annual Meeting 2015
    • Place of Presentation
      Pennsylvania Convention Center, Philadelphia, Pennsylvania, USA
    • Year and Date
      2015-04-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26830066
  • [Presentation] Regulatory mechanism of ESRP1 and ESRP2 proteins2013

    • Author(s)
      水谷アンナ、鯉沼代造、宮園浩平
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      神奈川、横浜(ポスター発表)
    • Data Source
      KAKENHI-PROJECT-24700968
  • [Presentation] An E3 ligase regulates ESRPs2013

    • Author(s)
      Mizutani A, Koinuma D and Miyazono K
    • Organizer
      TGF-bファミリーシグナル国際共同研究拠点第3回国際シンポジウム
    • Place of Presentation
      松山
    • Data Source
      KAKENHI-PROJECT-24700968
  • [Presentation] An E3 ligase regulates ESRPs2013

    • Author(s)
      Anna Mizutani, Daizo Koinuma, Kohei Miyazono
    • Organizer
      TGF-betaファミリーシグナル国際共同研究拠点第3回国際シンポジウム
    • Place of Presentation
      愛媛、松山(ポスター発表)
    • Data Source
      KAKENHI-PROJECT-24700968
  • [Presentation] Regulatory mechanism of ESRP1 and ESRP2 proteins2013

    • Author(s)
      水谷アンナ、鯉沼代造、宮園浩平
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24700968
  • [Presentation] The Arkadia-ESRP2 axis suppresses tumor progression: Analyses in clear cell renal cell carcinoma

    • Author(s)
      Anna Mizutani, Daizo Koinuma, Hiroyuki Seimiya, and Kohei Miyazono
    • Organizer
      AACR 2015
    • Place of Presentation
      Philadelphia, USA
    • Year and Date
      2015-04-18 – 2015-04-22
    • Data Source
      KAKENHI-PROJECT-26830066
  • [Presentation] Arkadia modulates the activity of epithelial splicing regulatory protein 2 (ESRP2)

    • Author(s)
      Anna Mizutani
    • Organizer
      TGF-beta Meeting 2014
    • Place of Presentation
      Leiden, The Nertherlands
    • Year and Date
      2014-05-08 – 2014-05-10
    • Data Source
      KAKENHI-PROJECT-26830066
  • [Presentation] Arkadiaによるスプライシング制御因子ESRP2の機能制御

    • Author(s)
      水谷アンナ、鯉沼代造、宮園浩平
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-26830066
  • 1.  KOINUMA Daizo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 2.  後藤 典子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 3.  宮園 浩平
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 4.  清宮 啓之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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