Kono Susumu 河野晋

… Alternative Names

河野晋コウノススム

Kohno Susumu 河野晋

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Researcher Number	30625463
Other IDs
External Links
Affiliation (Current)	2023: 金沢大学, がん進展制御研究所, 助教
Affiliation (based on the past Project Information) *help	2020 – 2021: 金沢大学, がん進展制御研究所, 助教 2016 – 2018: 金沢大学, がん進展制御研究所, 特任助教 2016: 金沢大学, がん進展制御研究所, 研究員 2015 – 2016: 金沢大学, がん進展制御研究所, 助教
Review Section/Research Field	Principal Investigator Tumor biology / Basic Section 50010:Tumor biology-related Except Principal Investigator Tumor biology
Keywords	Principal Investigator PGAM / RB / 糖代謝 / がん幹細胞 / グルコース代謝 / KDM5A / エピジェネティクス / MYC / 休眠細胞 Except Principal Investigator がん代謝 … More / RB / 解糖系 / 脂質代謝 / PGAM / がん抑制遺伝子 / がん / 代謝 / がん幹細胞 / コレステロール / 糖代謝 / グルタミン Less

晩期再発乳がんにおける休眠トリガーと分子機構の解明Principal Investigator
- Principal Investigator
  
  河野晋
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kanazawa University
Tumor progression through epigenetics remodeling by RB-PGAMPrincipal Investigator
- Principal Investigator
  
  Kohno Susumu
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Kanazawa University
Analysis of reprogrammed metabolism by PGAM in cancer stem cell modelPrincipal Investigator
- Principal Investigator
  
  Kohno Susumu
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Kanazawa University
Regulation of metabolism by RB tumor suppressor gene
- Principal Investigator
  
  Takahashi Chiaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  Kanazawa University

All 2021 2020 2019 2018 2017 2016 2015 2014

All Journal Article Presentation Book Patent

[Book] 『代謝変化とエピジェテックス制御』「RBがん抑制遺伝子産物による細胞未分化性制御」2016
- Author(s)
  河野晋、北嶋俊輔、佐々木信成、髙橋智聡.
- Total Pages
  7
- Publisher
  生化学
- Data Source
  KAKENHI-PROJECT-26290037
[Book] マウス甲状腺C細胞および線維芽細胞は高度な未分化性を獲得する. BioMedサーカス.com 最新研究情報「執筆者自身による研究論文レビュー第35回」2015
- Author(s)
  北嶋俊輔, 河野晋, 髙橋智聡
- Publisher
  BioMedサーカス.com
- Data Source
  KAKENHI-PROJECT-26290037
[Journal Article] Essential role of autophagy in protecting neonatal haematopoietic stem cells from oxidative stress in a p62-independent manner2021
- Author(s)
  Nomura Naho、Ito Chiaki、Ooshio Takako、Tadokoro Yuko、Kohno Susumu、Ueno Masaya、Kobayashi Masahiko、Kasahara Atsuko、Takase Yusuke、Kurayoshi Kenta、Si Sha、Takahashi Chiaki、Komatsu Masaaki、Yanagawa Toru、Hirao Atsushi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Pages: 1666-1666
- DOI
  10.1038/s41598-021-81076-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06657, KAKENHI-PROJECT-19K08860, KAKENHI-PROJECT-20K07566, KAKENHI-PLANNED-19H05706, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-18H02611, KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-19K22555, KAKENHI-PROJECT-19K17824, KAKENHI-PROJECT-19H03846, KAKENHI-PROJECT-20K07565, KAKENHI-PROJECT-20K07612, KAKENHI-PROJECT-16H06276
[Journal Article] Chemical inducer of regucalcin attenuates lipopolysaccharide‐induced inflammatory responses in pancreatic MIN6 β‐cells and RAW264.7 macrophages2021
- Author(s)
  Murata Tomiyasu、Hashimoto Kazunori、Kohno Susumu、Takahashi Chiaki、Yamaguchi Masayoshi、Ito Chihiro、Masataka Itoigawa、Kojima Roji、Hikita Kiyomi、Kaneda Norio
- Journal Title
  
  FEBS Open Bio
  
  Volume: 12 Pages: 175-191
- DOI
  10.1002/2211-5463.13321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-20K07612
[Journal Article] Treatment of RB1-intact hepatocellular carcinoma with CDK4/6 inhibitor combination therapy.2021
- Author(s)
  Sheng Jindan、Kohno Susumu、Okada Nobuhiro、Okahashi Nobuyuki、Teranishi Kana、Matsuda Fumio、Shimizu Hiroshi、Linn Paing、Nagatani Naoko、Yamamura Minako、Harada Kenichi、Horike Shin‐ichi、Inoue Hiroshi、Yano Seiji、Kumar Sharad、Kitajima Shunsuke、Ajioka Itsuki、Takahashi Chiaki
- Journal Title
  
  Hepatology
  
  Volume: 74 Pages: 1971-1993
- DOI
  10.1002/hep.31872
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07365, KAKENHI-PUBLICLY-20H04943, KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-20H04102, KAKENHI-PROJECT-20K07612
[Journal Article] Cytotoxic activity of dimeric acridone alkaloids derived from Citrus plants towards human leukaemia HL-60 cells2020
- Author(s)
  Murata Tomiyasu、Kohno Susumu、Ogawa Kazuma、Ito Chihiro、Itoigawa Masataka、Ito Masafumi、Hikita Kiyomi、Kaneda Norio
- Journal Title
  
  J. Pharm. Pharmacol.
  
  Volume: 72 Pages: 1445-1457
- DOI
  10.1111/jphp.13327
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07612, KAKENHI-PROJECT-19H01889
[Journal Article] Regucalcin enhances adipocyte differentiation and attenuates inflammation in 3T3-L1 cells.2020
- Author(s)
  Murata Tomiyasu、Yamaguchi Masayoshi、Kohno Susumu、Takahashi Chiaki、Risa Watanabe、Hatori Kanna、Hikita Kiyomi、Kaneda Norio
- Journal Title
  
  FEBS Open Bio.
  
  Volume: 10 Pages: 1967-1984
- DOI
  10.1002/2211-5463.12947
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07612, KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-19K22555
[Journal Article] Pharmacologically targetable vulnerability in prostate cancer carrying RB1-SUCLA2 deletion.2020
- Author(s)
  2. Kohno S*, Linn P*, Nagatani N, Watanabe Y, Kumar S, Soga T and Takahashi C. * equal contribution
- Journal Title
  
  Oncogene
  
  Volume: 39 Pages: 5690-5707
- DOI
  10.1038/s41388-020-1381-6
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07612, KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-19K22555, KAKENHI-PROJECT-16H06276
[Journal Article] Peripubertal High Fat Diet Promotes c-Myc Stabilization in Mammary Gland Epithelium.2020
- Author(s)
  Kulathunga Nilakshi、Kohno Susumu、Linn Paing、Nishimoto Yuuki、Horike Shin‐ichi、Zaraiskii Mikhail I.、Kumar Sharad、Muranaka Hayato、Takahashi Chiaki
- Journal Title
  
  Cancer Sci.
  
  Volume: 111 Pages: 2336-2348
- DOI
  10.1111/cas.14492
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07612, KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-19K22555
[Journal Article] Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD22019
- Author(s)
  Tatsunori Nishimura, Asuka Nakata, Xiaoxi Chen, Kurumi Nishi, Makiko Meguro-Horike, Soichiro Sasaki, Kenji Kita, Shin-ichi Horike, Kaori Saitoh, Keiko Kato, Kaori Igarashi, Takahiko Murayama, Susumu Kohno, Chiaki Takahashi, Naofumi Mukaida, Seiji Yano, Tomoyoshi Soga, Arinobu Tojo, Noriko Gotoh
- Journal Title
  
  Oncogene
  
  Volume: 38 Issue: 14 Pages: 2464-2481
- DOI
  10.1038/s41388-018-0589-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05615, KAKENHI-PROJECT-18H02679, KAKENHI-PROJECT-17K19586, KAKENHI-PROJECT-17K19587, KAKENHI-PROJECT-17K14992, KAKENHI-PROJECT-17K15021, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K22555, KAKENHI-PROJECT-17H03576
[Journal Article] Regucalcin confers resistance to amyloid-β toxicity in neuronally differentiated PC12 cells2018
- Author(s)
  Murata Tomiyasu、Yamaguchi Masayoshi、Kohno Susumu、Takahashi Chiaki、Kakimoto Mitsumi、Sugimura Yukiko、Kamihara Mako、Hikita Kiyomi、Kaneda Norio
- Journal Title
  
  FEBS Open Bio
  
  Volume: 8 Pages: 349-360
- DOI
  10.1002/2211-5463.12374
- NAID
  40021638634
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05615, KAKENHI-PROJECT-17H03576, KAKENHI-PROJECT-17K19586, KAKENHI-PROJECT-17K14992, KAKENHI-PROJECT-16K08252
[Journal Article] The RB-IL-6 axis controls self-renewal and endocrine therapy resistance by fine-tuning mitochondrial activity2017
- Author(s)
  Kitajima S、Yoshida A、Kohno S、Li F、Suzuki S、Nagatani N、Nishimoto Y、Sasaki N、Muranaka H、Wan Y、Thai T C、Okahashi N、Matsuda F、Shimizu H、Nishiuchi T、Suzuki Y、Tominaga K、Gotoh N、Suzuki M、Ewen M E、Barbie D A、Hirose O、Tanaka T、Takahashi C
- Journal Title
  
  Oncogene
  
  Volume: 36 Pages: 5145-5157
- DOI
  10.1038/onc.2017.124
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19586, KAKENHI-PROJECT-17K14992, KAKENHI-PUBLICLY-17H05615, KAKENHI-PROJECT-16J40231, KAKENHI-PROJECT-17J06037, KAKENHI-PROJECT-17H03576
[Journal Article] MicroRNA-140 mediates RB tumor suppressor function to control stem cell-like activity through interleukin-62017
- Author(s)
  Yoshida A, Kitajima S, Li F, Chaoyang C, Yujiro T, Susumu K, Wan Y, Naoyuki H, Hayato M, Nishimoto Y, Nagatani N, Nishiuchi T, Thai T C, Suzuki S, Nakao S, Tanaka T, Hirose O, Barbie D A and Takahashi C.
- Journal Title
  
  Oncotarget.
  
  Volume: 印刷中 Pages: 13872-13885
- DOI
  10.18632/oncotarget.14681
- NAID
  120006226780
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01487, KAKENHI-PROJECT-26290037, KAKENHI-PROJECT-26430105, KAKENHI-PROJECT-16KK0197, KAKENHI-PROJECT-17K19586, KAKENHI-PROJECT-17K14992, KAKENHI-PUBLICLY-17H05615, KAKENHI-PROJECT-17H03576
[Journal Article] A distinct function of the retinoblastoma protein in the control of lipid composition identified by lipidomic profiling.2017
- Author(s)
  Muranaka H、Hayashi A、Minami K、Kitajima S、Kohno S、Nishimoto Y、Nagatani N、Suzuki M、Kulathunga L A N、Sasaki N、Okada N、Matsuzaka T、Shimano H、Tada H、Takahashi C
- Journal Title
  
  Oncogenesis.
  
  Volume: 6
- DOI
  10.1038/oncsis.2017.51
- NAID
  120007134535
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19586, KAKENHI-PROJECT-17K14992, KAKENHI-PUBLICLY-17H05615, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03093, KAKENHI-PROJECT-17J06037, KAKENHI-PROJECT-17H03576
[Journal Article] Glucoraphanin Ameliorates Obesity and Insulin Resistance Through Adipose Tissue Browning and Reduction of Metabolic Endotoxemia in Mice.2017
- Author(s)
  Nagata N, Xu L, Kohno S, Ushida Y, Aoki Y, Umeda R, Fuke N, Zhuge F, Ni Y, Nagashimada M, Takahashi C, Suganuma H, Kaneko S and Ota T.
- Journal Title
  
  Diabetes
  
  Volume: 印刷中 Pages: 1222-1236
- DOI
  10.2337/db16-0662
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01487, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-15H05345, KAKENHI-PROJECT-26290037, KAKENHI-PROJECT-15K00813, KAKENHI-PROJECT-17K19586, KAKENHI-PROJECT-17K14992, KAKENHI-PUBLICLY-17H05615, KAKENHI-PROJECT-16H03035, KAKENHI-PROJECT-17H03576
[Journal Article] Stem cell strategies shared by cancer cells: the role of RB tumor suppressor2016
- Author(s)
  Kohno S, Kitajima S, Sasaki N and Takahashi C.
- Journal Title
  
  World J Stem Cells
  
  Volume: 8 Pages: 170-184
- DOI
  10.4252/wjsc.v8.i4.170
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01487, KAKENHI-PROJECT-26290037, KAKENHI-PROJECT-15K18404
[Journal Article] Therapeutic strategy for targeting aggressive malignant gliomas by disrupting their energy balance.2016
- Author(s)
  Hegazy AM, Yamada D, Kobayashi M, Kohno S, Ueno M, Ali MA, Ohta K, Tadokoro Y, Ino Y, Todo T, Soga T, Takahashi C and Hirao A.
- Journal Title
  
  J Biol Chem
  
  Volume: 291 Pages: 170-184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26290037
[Journal Article] Metabolic characterization of cultured mammalian cells by mass balance analysis, tracer labeling experiments and computer-aided simulations.2015
- Author(s)
  Okahashi N, Kohno S, Kitajima S, Matsuda F, Takahashi C, Shimizu H.
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 120 Issue: 6 Pages: 725-731
- DOI
  10.1016/j.jbiosc.2015.04.003
- NAID
  110010022659
- ISSN
  1389-1723
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K18404, KAKENHI-PUBLICLY-15H01487, KAKENHI-PROJECT-15J05988, KAKENHI-PROJECT-26640070, KAKENHI-PROJECT-26290037
[Journal Article] Undifferentiated state induced by Rb-p53 double inactivation in mouse thyroid neuroendocrine cells and embryonic fibroblasts.2015
- Author(s)
  Kitajima S, Kohno S, Kondoh A, Sasaki N, Nishimoto Y, Li F, Mohammed MS, Muranaka H, Nagatani N, Suzuki M, Kido Y, Takahashi C
- Journal Title
  
  Stem Cells.
  
  Volume: - Pages: 1657-1669
- DOI
  10.1002/stem.1971
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25830076, KAKENHI-PROJECT-25830077, KAKENHI-PROJECT-26640070, KAKENHI-PROJECT-15K18404, KAKENHI-PUBLICLY-15H01487, KAKENHI-PROJECT-26290037
[Journal Article] An in vitro system to characterize prostate cancer progression identified signaling required for self-renewal.2015
- Author(s)
  Salah M, Nishimoto Y, Kohno S, Kondoh A, Kitajima S, Muranaka H, Nishiuchi T, Ibrahim A, Yoshida A, Takahashi C.
- Journal Title
  
  Molecular Carcinogenesis
  
  Volume: in press
- DOI
  10.1002/mc.22444
- NAID
  120005973612
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18404, KAKENHI-PUBLICLY-15H01487, KAKENHI-PROJECT-26640070, KAKENHI-PROJECT-26290037
[Patent] ＲＢ１陽性癌の治療用医薬組成物及びキット2020
- Inventor(s)
  高橋智聡、河野晋、盛金丹
- Industrial Property Rights Holder
  高橋智聡、河野晋、盛金丹
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-20K07612
[Presentation] Pharmacologically targetable vulnerability in prostate cancer carrying RB1-SUCLA2 loss.2021
- Author(s)
  Kohno Susumu, Paing Linn, Mishiro Kenji, Kunishima Munetaka, Watanabe Yoshihiro and Takahashi Chiaki.
- Organizer
  AACR Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07612
[Presentation] Pharmacologically targetable metabolic vulnerability in prostate cancer carrying RB1-SUCLA2 deletion.2021
- Author(s)
  Kohno Susumu, Paing Linn, Soga Tomoyoshi, Takahashi Chiaki.
- Organizer
  Keystone symposia tumor metabolism and microenvironment
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07612
[Presentation] RB-コレステロールによる未分化性維持機構の解明2021
- Author(s)
  河野晋, 佐々木信成, 高橋智聡
- Organizer
  第94回日本生化学大
- Data Source
  KAKENHI-PROJECT-20K07612
[Presentation] RB1-SUCLA2欠失による代謝脆弱性を標的とした前立腺がん治療法の開発2021
- Author(s)
  河野晋, 高橋智聡
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07612
[Presentation] RB欠損に付随する代謝遺伝子欠損を標的とした治療法の探索2020
- Author(s)
  河野晋
- Organizer
  第1回日本癌学会若手の会
- Data Source
  KAKENHI-PROJECT-20K07612
[Presentation] NFYAによる乳がん悪性化機構への影響2020
- Author(s)
  植木ちひろ、辻本剛己、河野晋、高橋智聡、岡田宣宏
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K07612
[Presentation] 進行前立腺がんにおけるRB1-SUCLA2遺伝子欠失を標的とする新規治療2020
- Author(s)
  高橋智聡、Paing Linn、曽我朋義、河野晋
- Organizer
  第58回日本癌治療学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07612
[Presentation] RB1-SUCLA2 欠損による代謝脆弱性を標的とした前立腺がん治療法の探索2020
- Author(s)
  河野晋、曽我朋義、高橋智聡
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-20K07612
[Presentation] RB欠損に付随する代謝遺伝子欠損を標的とした治療法の探索2020
- Author(s)
  河野晋
- Organizer
  第2回金沢大学がん進展制御研究所・国立がん研究センター研究所若手研究発表会
- Data Source
  KAKENHI-PROJECT-20K07612
[Presentation] KDM5AとRBが制御する代謝分子の探索2018
- Author(s)
  3.河野晋, 岡橋伸幸, 松田史生, 清水浩, 髙橋智聡.
- Organizer
  第6回がんと代謝研究会
- Data Source
  KAKENHI-PROJECT-17K14992
[Presentation] ストン脱メチル化酵素KDM5AとRBが制御する代謝分子の探索.2018
- Author(s)
  河野晋, 岡橋伸幸, 松田史生, 清水浩, 髙橋智聡.
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K14992
[Presentation] RB controls differentiation through positive regulation of phosphoglycerate mutases.2018
- Author(s)
  Kohno S and Takahashi C.
- Organizer
  Abcam Cancer and Metabolism conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K14992
[Presentation] ヒストン脱メチル化酵素KDM5AとRBが制御する代謝分子の探索.2018
- Author(s)
  河野晋, 岡橋伸幸, 松田史生, 清水浩, 髙橋智聡.
- Organizer
  第1回金沢大学がん進展制御研究所・国立がん研究センター研究所若手研究発表会
- Data Source
  KAKENHI-PROJECT-17K14992
[Presentation] 悪性進展過程におけるRBの代謝調節機能2017
- Author(s)
  河野晋, 岡橋伸幸, 松田史生, 清水浩, 髙橋智聡
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17K14992
[Presentation] 前立腺がんにおけるRBホモ欠損に伴う脆弱性の獲得2017
- Author(s)
  河野晋, Paing Linn, 髙橋智聡
- Organizer
  第5回がんと代謝研究会
- Data Source
  KAKENHI-PROJECT-17K14992
[Presentation] Metabolic rewiring in Rb deficient cells during cancer progression.2016
- Author(s)
  Kohno S, Okahashi N, Kitajima S Suzuki S, Tanaka T, Matsuda F, Shimizu H and Takahashi C.
- Organizer
  AACR Annual Meeting 2016
- Place of Presentation
  New Orleans USA/Ernest N. Morial Convention Center
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] CONTROL OF GLUCOSE METABOLISM BY RB.2016
- Author(s)
  Kohno S, Takahashi C
- Organizer
  Translational research in cancer cell metabolism
- Place of Presentation
  Palacio Euskalduna Jauregia /ビルバオスペイン
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] Phosphoglyceratemutases (PGAMs) mediate RB function to control differentiation.2016
- Author(s)
  Kohno S and Takahashi C
- Organizer
  Fourth International Rb Meeting
- Place of Presentation
  コロンバス　オハイオ州
- Year and Date
  2016-09-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18404
[Presentation] Metabolic rewiring in Rb deficient cells during cancer progression2016
- Author(s)
  Kohno S, Okahashi N, Kitajima S Suzuki S, Tanaka T, Matsuda F, Shimizu H and Takahashi C.
- Organizer
  AACR Annual Meeting 2016
- Place of Presentation
  New Orleans USA
- Year and Date
  2016-04-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18404
[Presentation] RB function in controlling glycolysis.2016
- Author(s)
  Kohno S, Kitajima S and Takahashi C.
- Organizer
  Keystone Symposia
- Place of Presentation
  Banff, Canada/Fairmont Banff Springs
- Year and Date
  2016-02-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] Phosphoglyceratemutases (PGAMs) mediate RB function to control differentiation.2016
- Author(s)
  Kohno S and Takahashi C.
- Organizer
  Fourth International Rb Meeting
- Place of Presentation
  Hilton Columbus Downtown /コロンバス　オハイオ州
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] RBがん抑制遺伝子による代謝制御と細胞未分化性2016
- Author(s)
  髙橋智聡, 北嶋俊輔, 河野晋
- Organizer
  第68回日本細胞生物学会大会
- Place of Presentation
  京都/京都テルサ
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] Control of glucose metabolism by RB2016
- Author(s)
  Kohno S　and Takahashi C
- Organizer
  Translational research in cancer cell metabolism
- Place of Presentation
  ビルバオスペイン
- Year and Date
  2016-10-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18404
[Presentation] RBの中心炭素代謝制御機能2016
- Author(s)
  河野晋, 髙橋智聡
- Organizer
  第4回がんと代謝研究会
- Place of Presentation
  鹿児島
- Year and Date
  2016-07-07
- Data Source
  KAKENHI-PROJECT-15K18404
[Presentation] Rb不活性化による代謝リワイヤリング機構の解明2015
- Author(s)
  河野晋，岡橋伸幸，北嶋俊輔，鈴木佐和子，田中知明，松田史生，清水浩，高橋智聡
- Organizer
  平成27年度がん若手研究者ワークショップ
- Place of Presentation
  蓼科/蓼科グランドホテル
- Year and Date
  2015-09-05
- Data Source
  KAKENHI-PROJECT-15K18404
[Presentation] Rb不活性化による代謝リワイヤリング機構の解明2015
- Author(s)
  河野晋，岡橋伸幸，北嶋俊輔，鈴木佐和子，田中知明，松田史生，清水浩，高橋智聡
- Organizer
  第38回日本分子生物学会年会　第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸/神戸ポートアイランド
- Year and Date
  2015-12-04
- Data Source
  KAKENHI-PROJECT-15K18404
[Presentation] Rb不活性化による代謝リワイヤリング機構の解明2015
- Author(s)
  河野晋，岡橋伸幸，北嶋俊輔，鈴木佐和子，田中知明，松田史生，清水浩，高橋智聡
- Organizer
  第3回がんと代謝研究会
- Place of Presentation
  金沢/石川県立音楽堂
- Year and Date
  2015-07-16
- Data Source
  KAKENHI-PROJECT-15K18404
[Presentation] The metabolic function of RB in controlling mevalonate (MVA) pathway regulates tumor progression2015
- Author(s)
  Sasaki N, Kitajima S, Muranaka H, Shamma A, Kohno S, Takahashi C
- Organizer
  Keystone Symposia
- Place of Presentation
  Vancouver・Canada・Fairmont Hotel
- Year and Date
  2015-01-16
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] Rb不活性化に伴うメタボリックリワイヤリング機構の解明2015
- Author(s)
  河野晋，北嶋俊輔，鈴木佐和子，田中知明，佐々木信成，村中勇人，高橋智聡
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋/名古屋国際会議場
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-15K18404
[Presentation] Control of cellular metabolism by tumor suppressors2015
- Author(s)
  Susumu Kohno
- Organizer
  2015 Kanazawa University Cancer Research Institute Fudan University Shanghai Cancer Center Joint Symposium
- Place of Presentation
  金沢/金沢大学　医学部記念館
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-15K18404
[Presentation] The metabolic function of RB in controlling mevalonate (MVA) pathway and tumor progression.2014
- Author(s)
  Sasaki N, Muranaka H, Kitajima S, Kohno S, Shamma A and Takahashi C
- Organizer
  第37回日本癌学会学術総会
- Place of Presentation
  神奈川県・横浜市・パシフィコ横浜
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] Rbによるサイトカインを介したがん悪性化制御機構の解明2014
- Author(s)
  北嶋俊輔, 吉田晶代, 河野晋, 鈴木佐和子, 田中知明, 後藤典子, 髙橋智聡
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  神奈川県・横浜市・パシフィコ横浜
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] RBによるメバロン酸経路を介したがん悪性進展制御機構.2014
- Author(s)
  佐々木信成, 村中勇人, 北嶋俊輔, 河野晋, Shamma A, 髙橋智聡
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  神奈川県・横浜市・パシフィコ横浜
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] RBの中心代謝制御機能2014
- Author(s)
  河野晋, 北嶋俊輔, 吉田晶代, 鈴木佐和子, 田中知明, 佐々木信成, 村中勇人, 髙橋智聡
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  神奈川県・横浜市・パシフィコ横浜
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] がん抑制遺伝子RBによるSREBP-1の制御とがんにおける役割の解析2014
- Author(s)
  村中勇人, 北嶋俊輔, 佐々木信成, 河野晋, 吉田晶代, 丹下正一朗, 鈴木健之, 林昭夫, 多田秀昭, Shamma A, 髙橋智聡
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  神奈川県・横浜市・パシフィコ横浜
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] RB不活性化によって誘導されるがん幹細胞様未分化状態におけるPgam2の役割2014
- Author(s)
  河野晋, 北嶋俊輔, 佐々木信成, 村中勇人, 鈴木佐和子, 田中知明, 岡橋伸幸, 松田史生, 清水浩, 髙橋智聡
- Organizer
  第2回がんと代謝研究会
- Place of Presentation
  東京都・葛飾区・東京理科大学
- Year and Date
  2014-07-16
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] Reductive glutamine metabolism in p53-null soft tissue sarcoma cells.2014
- Author(s)
  Okahashi N, Matsuda F, Kohno S, Takahashi C and Shimizu H.
- Organizer
  Metabolomics 2014.
- Place of Presentation
  山形県・鶴岡市・慶応大学鶴岡キャンパス
- Year and Date
  2014-06-05
- Data Source
  KAKENHI-PROJECT-26290037

1. Takahashi Chiaki (50283619)

# of Collaborated Projects: 1 results

# of Collaborated Products: 25 results
2. Hayashi Naoyuki (50253456)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. Kitajima Syunsuke (90566465)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results
4. Shamma Awad (50402839)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. Sasaki Nobunari (40415170)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
6. Nakata Asuka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. Nishi Kurumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. Meguro Makiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. Sasaki Soichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. Kita Kenji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. Horike Shin-ichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. Saito Kaori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. Kato Keiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. Igarashi Kaori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. Murayama Takahiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. Mukaida Naofumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. Yano Seiji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. Soga Tomoyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. Tojo Arinobu

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
20. Gotoh Noriko

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
21. OTA Tsuguhito

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. NAGATA Naoto

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
23. ABE Manabu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. Hikita Kiyomi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 田中知明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 鈴木佐和子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 村田富保

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
28. 伊藤昌文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 笠原敦子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 田所優子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 小林昌彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 小松雅明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 平尾敦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 倉吉健太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 柳川徹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 上野将也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 松坂賢

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 島野仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 西村建徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. Chen Xiaoxi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 高橋智

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
42. 金子周一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 永島田まゆみ

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 井上啓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kono Susumu 河野 晋

河野 晋 コウノ ススム

Kohno Susumu 河野 晋

Research Projects

Research Products

Co-Researchers

晩期再発乳がんにおける休眠トリガーと分子機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Tumor progression through epigenetics remodeling by RB-PGAMPrincipal Investigator

Principal Investigator

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Analysis of reprogrammed metabolism by PGAM in cancer stem cell modelPrincipal Investigator

Principal Investigator

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Regulation of metabolism by RB tumor suppressor gene

Principal Investigator

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Research Institution

[Book] 『代謝変化とエピジェテックス制御』「RBがん抑制遺伝子産物による細胞未分化性制御」2016

Author(s)

Total Pages

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Data Source

[Book] マウス甲状腺C細胞および線維芽細胞は高度な未分化性を獲得する. BioMedサーカス.com 最新研究情報「執筆者自身による研究論文レビュー 第35回」2015

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[Journal Article] Essential role of autophagy in protecting neonatal haematopoietic stem cells from oxidative stress in a p62-independent manner2021

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[Journal Article] Chemical inducer of regucalcin attenuates lipopolysaccharide‐induced inflammatory responses in pancreatic MIN6 β‐cells and RAW264.7 macrophages2021

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[Journal Article] Treatment of RB1-intact hepatocellular carcinoma with CDK4/6 inhibitor combination therapy.2021

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[Journal Article] Cytotoxic activity of dimeric acridone alkaloids derived from Citrus plants towards human leukaemia HL-60 cells2020

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[Journal Article] Regucalcin enhances adipocyte differentiation and attenuates inflammation in 3T3-L1 cells.2020

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[Journal Article] Pharmacologically targetable vulnerability in prostate cancer carrying RB1-SUCLA2 deletion.2020

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[Journal Article] Peripubertal High Fat Diet Promotes c-Myc Stabilization in Mammary Gland Epithelium.2020

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[Journal Article] Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD22019

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[Journal Article] Regucalcin confers resistance to amyloid-β toxicity in neuronally differentiated PC12 cells2018

Kono Susumu 河野晋

河野晋コウノススム

Kohno Susumu 河野晋

[Book] マウス甲状腺C細胞および線維芽細胞は高度な未分化性を獲得する. BioMedサーカス.com 最新研究情報「執筆者自身による研究論文レビュー第35回」2015