• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Horie Kayo  堀江 香代

ORCIDConnect your ORCID iD *help
Researcher Number 30626825
Other IDs
Affiliation (Current) 2025: 弘前大学, 保健学研究科, 准教授
Affiliation (based on the past Project Information) *help 2022 – 2024: 弘前大学, 保健学研究科, 准教授
2015 – 2021: 弘前大学, 保健学研究科, 助教
Review Section/Research Field
Principal Investigator
Basic Section 08030:Family and consumer sciences, and culture and living-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Tumor biology
Except Principal Investigator
Basic Section 08030:Family and consumer sciences, and culture and living-related / Eating habits
Keywords
Principal Investigator
miRNA / エクソソーム / 卵巣癌 / 動脈硬化 / カシス / micro RNA(miRNA) / 植物由来エクソソーム様ナノ粒子 / マイクロRNA / 腹水 / micro RNA … More / exosome / 腫瘍マーカー / 卵巣明細胞癌 / micro array / microRNA / microRNa … More
Except Principal Investigator
フィトエストロゲン / カシス / エストロゲン受容体 / 更年期症状 / リグノイド / エストロゲン / 食品 / 皮膚 / 更年期 / 血管内皮機能 Less
  • Research Projects

    (6 results)
  • Research Products

    (41 results)
  • Co-Researchers

    (10 People)
  •  カシス由来ナノ粒子(ELNs)内在miRNAの動脈硬化抑制効果の検証と分子機構の解明Principal Investigator

    • Principal Investigator
      堀江 香代
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 08030:Family and consumer sciences, and culture and living-related
    • Research Institution
      Hirosaki University
  •  カシス由来新規機能性リグノイドの更年期症状に対する軽減効果の検証と分子機構の解明

    • Principal Investigator
      七島 直樹
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 08030:Family and consumer sciences, and culture and living-related
    • Research Institution
      Aomori University of Health and Welfare
  •  Search for novel plant-derived estrogens and evaluation of their effect on alleviation menopausal symptoms

    • Principal Investigator
      Nanashima Naoki
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 08030:Family and consumer sciences, and culture and living-related
    • Research Institution
      Aomori University of Health and Welfare
      Hirosaki University
  •  卵巣癌エクソソーム内在miR574-3Pを用いた腹膜播種の抑制Principal Investigator

    • Principal Investigator
      堀江 香代
    • Project Period (FY)
      2019 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Hirosaki University
  •  Effects of blackcurrant phytoestrogens on vascular endothelium and skin

    • Principal Investigator
      Naoki Nanashima
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Eating habits
    • Research Institution
      Hirosaki University
  •  Profiling of human ovarian cancer using comprehensive microRNA analysis and clarify of mechanism.Principal Investigator

    • Principal Investigator
      Horie Kayo
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor biology
    • Research Institution
      Hirosaki University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation Patent

  • [Journal Article] Microorganisms involved in the preparation of “<i>Sushiko</i>,” a fermented food produced in Tsugaru, Aomori, Japan2023

    • Author(s)
      堀江祐範,七島直樹
    • Journal Title

      Journal of the Japanese Society of Taste Technology

      Volume: 22 Issue: 1 Pages: 6-13

    • DOI

      10.11274/bimi.22.1_6

    • ISSN
      2186-7224, 2186-7232
    • Language
      Japanese
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K02038, KAKENHI-PROJECT-20K02402
  • [Journal Article] Exosomal MicroRNA as Biomarkers for Diagnosing or Monitoring the Progression of Ovarian Clear Cell Carcinoma: A Pilot Study2022

    • Author(s)
      Horie Kayo、Nanashima Naoki、Yokoyama Yoshihito、Yoshioka Haruhiko、Watanabe Jun
    • Journal Title

      Molecules

      Volume: 27 Issue: 12 Pages: 3953-3953

    • DOI

      10.3390/molecules27123953

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07748, KAKENHI-PROJECT-20K02402, KAKENHI-PROJECT-20K09589
  • [Journal Article] Hypocholesterolemic Effect of Blackcurrant ( Ribes nigrum) Extract in Healthy Female Subjects: A Pilot Study2021

    • Author(s)
      Naoki Nanashima, Kayo Horie, Maiko Kitajima, Shizuka Takamagi, Kasumi Mikami, Naoya In, Toshiko Tomisawa
    • Journal Title

      Molecules

      Volume: 26 Issue: 13 Pages: 4085-4085

    • DOI

      10.3390/molecules26134085

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K02402
  • [Journal Article] Blackcurrant (Ribes nigrum L.) Extract Exerts Potential Vasculoprotective Effects in Ovariectomized Rats, Including Prevention of Elastin Degradation and Pathological Vascular Remodeling.2021

    • Author(s)
      Horie K, Nanashima N, Maeda H, Tomisawa T, Oey I.
    • Journal Title

      Nutrients

      Volume: 13 Issue: 2 Pages: 560-560

    • DOI

      10.3390/nu13020560

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K02402
  • [Journal Article] Potential Vasculoprotective Effects of Blackcurrant ( Ribes nigrum) Extract in Diabetic KK-A y Mice2021

    • Author(s)
      Kayo Horie, Hayato Maeda, Naoki Nanashima, Indrawati Oey
    • Journal Title

      Molecules

      Volume: 26 Issue: 21 Pages: 6459-6459

    • DOI

      10.3390/molecules26216459

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K02402
  • [Journal Article] Blackcurrant (Ribes nigrum) Extract Prevents Dyslipidemia and Hepatic Steatosis in Ovariectomized Rats2020

    • Author(s)
      Naoki Nanashima, Kayo Horie, Kanako Yamanouchi, Toshiko Tomisawa, Maiko Kitajima, Indrawati Oey, Hayato Maeda
    • Journal Title

      Nutrients

      Volume: 12 Issue: 5 Pages: 1541-1541

    • DOI

      10.3390/nu12051541

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K02402
  • [Journal Article] Phytoestrogenic Effects of Blackcurrant Anthocyanins Increased Endothelial Nitric Oxide Synthase (eNOS) Expression in Human Endothelial Cells and Ovariectomized Rats2019

    • Author(s)
      Horie Kayo、Nanashima Naoki、Maeda Hayato
    • Journal Title

      Molecules

      Volume: 24 Issue: 7 Pages: 1259-1259

    • DOI

      10.3390/molecules24071259

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K00844
  • [Journal Article] Blackcurrant Extract with Phytoestrogen Activity Alleviates Hair Loss in Ovariectomized Rats2019

    • Author(s)
      Nanashima Naoki、Horie Kayo
    • Journal Title

      Molecules

      Volume: 24 Issue: 7 Pages: 1272-1272

    • DOI

      10.3390/molecules24071272

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K00844
  • [Journal Article] Effects of Blackcurrant Anthocyanin on Endothelial Function and Peripheral Temperature in Young Smokers.2019

    • Author(s)
      Toshiko Tomisawa, Naoki Nanashima, Maiko Kitajima, Kasumi Mikami, Shizuka Takamagi, Hayato Maeda, Kayo Horie, Fu-chih Lai,Tomohiro Osanai
    • Journal Title

      Molecules

      Volume: 24 Issue: 23 Pages: 4295-4295

    • DOI

      10.3390/molecules24234295

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K00844
  • [Journal Article] Blackcurrant Anthocyanins Increase the Levels of Collagen, Elastin, and Hyaluronic Acid in Human Skin Fibroblasts and Ovariectomized Rats2018

    • Author(s)
      Nanashima Naoki、Horie Kayo、Maeda Hayato、Tomisawa Toshiko、Kitajima Maiko、Nakamura Toshiya
    • Journal Title

      Nutrients

      Volume: 10 Issue: 4 Pages: 495-495

    • DOI

      10.3390/nu10040495

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K00844, KAKENHI-PROJECT-18K11068
  • [Journal Article] Hair keratin KRT81 is expressed in normal and breast cancer cells and contributes to their invasiveness.2017

    • Author(s)
      Naoki Nanashima, Kayo Horie, Toshiyuki Yamada, Takeshi Shimizu, Shigeki Tsuchida.
    • Journal Title

      Oncology reports

      Volume: 37 Issue: 5 Pages: 2964-2970

    • DOI

      10.3892/or.2017.5564

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K00844
  • [Journal Article] Phytoestrogenic Activity of Blackcurrant Anthocyanins Is Partially Mediated through Estrogen Receptor Beta2017

    • Author(s)
      Nanashima Naoki、Horie Kayo、Maeda Hayato
    • Journal Title

      Molecules

      Volume: 23 Issue: 1 Pages: 74-74

    • DOI

      10.3390/molecules23010074

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K00844
  • [Journal Article] Anthocyanin-rich blackcurrant extract inhibits proliferation of the MCF10A healthy human breast epithelial cell line through induction of G0/G1 arrest and apoptosis2017

    • Author(s)
      Nanashima Naoki、Horie Kayo、Chiba Mitsuru、Nakano Manabu、Maeda Hayato、Nakamura Toshiya
    • Journal Title

      Molecular Medicine Reports

      Volume: 16 Issue: 5 Pages: 6134-6141

    • DOI

      10.3892/mmr.2017.7391

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K00844, KAKENHI-PROJECT-17K19779, KAKENHI-PROJECT-17H04761
  • [Patent] 更年期症状改善用組成物2019

    • Inventor(s)
      堀江香代、七島直樹
    • Industrial Property Rights Holder
      弘前大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2019-093226
    • Filing Date
      2019
    • Data Source
      KAKENHI-PROJECT-16K00844
  • [Presentation] カシス抽出物は骨芽細胞様細胞の分化を誘導する2023

    • Author(s)
      七島 直樹、堀江 香代、Indrawati Oey
    • Organizer
      第77回日本栄養・食糧学会大会
    • Data Source
      KAKENHI-PROJECT-23K02038
  • [Presentation] 卵巣癌細胞株培養上清エクソソーム内在miRNAを用いた明細胞癌マーカーの探索2023

    • Author(s)
      堀江香代
    • Organizer
      第64回 日本臨床細胞学会総会(春期大会)
    • Data Source
      KAKENHI-PROJECT-19K07748
  • [Presentation] カシスに含まれる新規フィトエストロゲンの探索および活性評価2023

    • Author(s)
      七島直樹、堀江香代、前多隼人、加藤陽治
    • Organizer
      2023年度青森県 保健医療福祉研究発表会 日本ヒューマンケア科学学会第16回学術集会 合同集会
    • Data Source
      KAKENHI-PROJECT-20K02402
  • [Presentation] カシスに含まれる新規フィトエストロゲンの探索および活性評価2023

    • Author(s)
      七島直樹、堀江香代、前多隼人、加藤陽治
    • Organizer
      2023年度青森県保健医療福祉研究発表会・日本ヒューマンケア科学学会第16回学術集会 合同集会
    • Data Source
      KAKENHI-PROJECT-23K02038
  • [Presentation] ヒト皮膚線維芽細胞におけるEstrogen-related receptorαの機能解析2023

    • Author(s)
      七島直樹、乗鞍敏夫、中野学、堀江香代
    • Organizer
      第46回 日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-23K02038
  • [Presentation] ヒト皮膚線維芽細胞におけるEstrogen-related receptorαの機能解析2023

    • Author(s)
      七島直樹、乗鞍敏夫、中野学、堀江香代
    • Organizer
      第46回 日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-20K02402
  • [Presentation] カシス抽出物は骨芽細胞様細胞の分化を誘導する2023

    • Author(s)
      七島直樹、堀江香代、Indrawati Oey
    • Organizer
      第77回 日本栄養・食料学会
    • Data Source
      KAKENHI-PROJECT-20K02402
  • [Presentation] 卵巣癌細胞株培養上清エクソソーム内在miRNAを用いた明細胞癌マーカーの探索2023

    • Author(s)
      堀江香代
    • Organizer
      第64回日本臨床細胞学会総会
    • Data Source
      KAKENHI-PROJECT-19K07748
  • [Presentation] カシス抽出物は更年期モデルラットにおける脂質異常症を軽減する2022

    • Author(s)
      七島直樹、堀江香代、前多隼人、Indrawati Oey
    • Organizer
      2022年度青森県保健医療福祉研究発表会・日本ヒューマンケア科学学会第15回学術集会 合同集会
    • Data Source
      KAKENHI-PROJECT-20K02402
  • [Presentation] Alleviating effects of blackcurrant extract against dyslipidemia in menopausal and diabetic animal models2022

    • Author(s)
      七島直樹、堀江香代、前多隼人
    • Organizer
      第45回日本分子生物学会年会 日本生物物理学会 共催
    • Data Source
      KAKENHI-PROJECT-20K02402
  • [Presentation] 卵巣癌患者腹水エクソソーム回収および内在microRNA解析のための実験系の確立2021

    • Author(s)
      堀江香代
    • Organizer
      第62回日本臨床細胞学会
    • Data Source
      KAKENHI-PROJECT-19K07748
  • [Presentation] 卵巣癌患者腹水エクソソーム回収および内在microRNA解析のための実験系の確立2021

    • Author(s)
      堀江香代
    • Organizer
      第62回 日本臨床細胞学会総会 web開催
    • Data Source
      KAKENHI-PROJECT-19K07748
  • [Presentation] 更年期モデルラットにおけるカシス抽出物の脂質異常症に対する軽減効果2020

    • Author(s)
      Naoki Nanashima, Kayo Horie, Indrawati Oey, Hayato Maeda
    • Organizer
      第74回日本栄養・食糧学会大会
    • Data Source
      KAKENHI-PROJECT-20K02402
  • [Presentation] 卵巣癌由来腹水エクソソーム回収および内在micro RNA 実験系の確立2020

    • Author(s)
      佐藤瑠璃、堀江香代,吉岡治彦、渡邊純
    • Organizer
      第69回日本医学検査学会 発表予定
    • Data Source
      KAKENHI-PROJECT-19K07748
  • [Presentation] ヒト卵巣癌細胞株で高発現を示したエクソソーム内在miRNAの検証2020

    • Author(s)
      堀江香代
    • Organizer
      第61回日本臨床細胞学会
    • Data Source
      KAKENHI-PROJECT-19K07748
  • [Presentation] 血管内皮細胞に対するカシスアントシアニンのフィトエストロゲン作用2019

    • Author(s)
      西山広亮, 七島直樹, 堀江香代, 前多隼人
    • Organizer
      日本油化学会第58回年会
    • Data Source
      KAKENHI-PROJECT-16K00844
  • [Presentation] エストロゲン受容体βを介したカシスアントシアニンのフィトエストロゲン作用2018

    • Author(s)
      七島直樹、堀江香代、前多隼人
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-16K00844
  • [Presentation] An Investigation of Exosomal Endogenous MicroRNA Profiles in Ovarian Cancer.2018

    • Author(s)
      Kayo Horie
    • Organizer
      The 25th Thai-Japanese Workshop in Diagnostic Cytopathology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06820
  • [Presentation] カシスアントシアニンが秘めるフィトエストロゲン活性の探索2017

    • Author(s)
      七島直樹, 堀江香代, 冨澤登志子, 北島麻衣子, 前多隼人
    • Organizer
      日本分子生物学会/日本生化学会 2017年度生命科学系学会合同年次大会
    • Data Source
      KAKENHI-PROJECT-16K00844
  • [Presentation] エストロゲン受容体αを介したカシスアントシアニンのフィトエストロゲン活性2017

    • Author(s)
      七島直樹, 堀江香代, 冨澤登志子, 北島麻衣子, 藤田俊文, 前多隼人, 加藤陽治
    • Organizer
      第71回日本栄養・食糧学会大会
    • Data Source
      KAKENHI-PROJECT-16K00844
  • [Presentation] Profiling of human ovarian cancer using comprehensive microRNA analysis.2017

    • Author(s)
      Kayo Horie
    • Organizer
      International congress of cytology (The 19th)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06820
  • [Presentation] 卵巣癌バイオマーカーとしてのエクソソーム内在microRNAの検討2017

    • Author(s)
      堀江香代
    • Organizer
      日本臨床細胞学会秋期大会(第56回)
    • Data Source
      KAKENHI-PROJECT-15K06820
  • [Presentation] ヒト卵巣癌エクソソーム内在miRNA発現プロファイルの探索2016

    • Author(s)
      堀江香代
    • Organizer
      日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Data Source
      KAKENHI-PROJECT-15K06820
  • [Presentation] 乳がん細胞におけるHair keratin 81の発現と浸潤への関与2016

    • Author(s)
      七島直樹, 堀江香代, 山田俊幸, 清水武史, 土田成紀.
    • Organizer
      第75回 日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-16K00844
  • [Presentation] ヒト卵巣癌エクソソーム内在miRNAと細胞内miRNA発現プロファイルの探索2016

    • Author(s)
      堀江香代
    • Organizer
      第57回日本臨床細胞学会総会
    • Place of Presentation
      パシフィコ横浜 神奈川県 横浜市
    • Year and Date
      2016-05-29
    • Data Source
      KAKENHI-PROJECT-15K06820
  • [Presentation] Profiling of human ovarian cancer using comprehensive microRNA analysis.2016

    • Author(s)
      堀江香代
    • Organizer
      The 19th International Congress of Cytology
    • Place of Presentation
      パシフィコ横浜 神奈川県 横浜市
    • Year and Date
      2016-05-30
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06820
  • [Presentation] 卵巣癌エクソソーム内在microRNAの探索2015

    • Author(s)
      堀江香代
    • Organizer
      平成27年度 がん若手ワークショップ
    • Place of Presentation
      蓼科グランドホテル 長野県 茅野市
    • Year and Date
      2015-09-04
    • Data Source
      KAKENHI-PROJECT-15K06820
  • 1.  Naoki Nanashima (80333730)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 25 results
  • 2.  渡邉 純 (10201188)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  前多 隼人 (80507731)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 4.  冨澤 登志子 (70333705)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 5.  北島 麻衣子 (70455731)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 6.  下田 浩 (20274748)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  堀江 祐範 (30514591)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results
  • 8.  二瓶 賢一 (10307209)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  Yokoyama Yoshihito
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  渡辺 純
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi