• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Sakoda Yukimi  佐古田 幸美

ORCIDConnect your ORCID iD *help
… Alternative Names

SAKODA Yukimi  佐古田 幸美

Less
Researcher Number 30629754
Other IDs
Affiliation (Current) 2025: 山口大学, 大学院医学系研究科, 准教授
Affiliation (based on the past Project Information) *help 2018 – 2024: 山口大学, 大学院医学系研究科, 准教授
2017: 山口大学, 大学院医学系研究科, 講師
2016: 山口大学, 医学(系)研究科(研究院), 講師
2015: 山口大学, 大学院医学系研究科, 助教
2012 – 2015: 山口大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field
Principal Investigator
Basic Section 49070:Immunology-related / Tumor therapeutics / Immunology
Except Principal Investigator
Tumor therapeutics / Medium-sized Section 50:Oncology and related fields / Ophthalmology
Keywords
Principal Investigator
キメラ抗原受容体 / 固形がん / 免疫チェックポイント分子 / CAR-NK細胞療法 / がん免疫 / シグナル伝達 / 癌 / 免疫学 / がん傷害活性 / 免疫チェックポイント … More / 免疫抑制シグナル / 免疫療法 / 共シグナル / 免疫 … More
Except Principal Investigator
がん免疫療法 / 遺伝子改変技術 / 免疫細胞療法 / がん免疫 / エピトープスプレッディング / 新規CAR-T細胞療法 / 免疫学 / 癌 / チトクロームP450 / チトクロームP / オメガ3脂肪酸 / ぶどう膜炎 / 加齢黄斑変性症 / 眼炎症 / 抗体医療 / ADCC活性 / NK細胞 / 抗体療法 / 遺伝子改変T細胞 / CAR-T細胞 Less
  • Research Projects

    (10 results)
  • Research Products

    (25 results)
  • Co-Researchers

    (12 People)
  •  Development of next-generation CAR-NK cell immunotherapy against solid tumorsPrincipal Investigator

    • Principal Investigator
      佐古田 幸美
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49070:Immunology-related
    • Research Institution
      Yamaguchi University
  •  Mechanistic analysis of novel CAR-T cell therapy against solid tumors

    • Principal Investigator
      玉田 耕治
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 50:Oncology and related fields
    • Research Institution
      Yamaguchi University
  •  Next generation CAR-T cell therapy for malignant melanomaPrincipal Investigator

    • Principal Investigator
      SAKODA YUKIMI
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49070:Immunology-related
    • Research Institution
      Yamaguchi University
  •  Cancer immunology research to enhance therapeutic effects of immune checkpoint blockade

    • Principal Investigator
      TAMADA Koji
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Tumor therapeutics
    • Research Institution
      Yamaguchi University
  •  Engineering CAR T cells for improved function against solid tumorsPrincipal Investigator

    • Principal Investigator
      SAKODA Yukimi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor therapeutics
    • Research Institution
      Yamaguchi University
  •  Elucidation of a destruction mechanism and development of new treatment on intraocular chronic inflammatory diseases with CYP metabolites

    • Principal Investigator
      YANAI Ryoji
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      Yamaguchi University
  •  Novel caner immunotherapy using gene-modification of Fc receptors

    • Principal Investigator
      TAMADA Koji
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Tumor therapeutics
    • Research Institution
      Yamaguchi University
  •  Development of novel CAR-T cell therapy against cancer

    • Principal Investigator
      TAMADA Koji
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor therapeutics
    • Research Institution
      Yamaguchi University
  •  Development of new engineered CAR-T cells with the ability to block immune checkpoint pathwaysPrincipal Investigator

    • Principal Investigator
      SAKODA Yukimi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Tumor therapeutics
    • Research Institution
      Yamaguchi University
  •  HVEMを標的とした自己免疫疾患に対する新規治療法の開発Principal Investigator

    • Principal Investigator
      佐古田 幸美
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Immunology
    • Research Institution
      Yamaguchi University

All 2022 2021 2019 2018 2017 2016 2015 2014

All Journal Article Presentation Book

  • [Book] キメラ抗原受容体発現T細胞(CAR-T)療法2017

    • Author(s)
      佐古田幸美、玉田耕治
    • Total Pages
      350
    • Publisher
      日本臨牀社
    • Data Source
      KAKENHI-PROJECT-16K07176
  • [Book] がん抗原の新しい概念2017

    • Author(s)
      佐古田幸美、玉田耕治
    • Total Pages
      94
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-16K07176
  • [Book] Adaptive immune resistance2017

    • Author(s)
      佐古田幸美
    • Total Pages
      94
    • Publisher
      ライフメディコム
    • Data Source
      KAKENHI-PROJECT-16K07176
  • [Journal Article] Novel technologies for improving the safety and efficacy of CAR-T cell therapy2022

    • Author(s)
      Ohta K, Sakoda Y, Tamada K
    • Journal Title

      Int J Hematol

      Volume: - Issue: 5 Pages: 647-651

    • DOI

      10.1007/s12185-022-03478-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21H04808
  • [Journal Article] Enhanced Antitumor Responses of Tumor Antigen-Specific TCR T Cells Genetically Engineered to Produce IL7 and CCL192021

    • Author(s)
      Tokunaga Yoshihiro、Sasaki Takahiro、Goto Shunsuke、Adachi Keishi、Sakoda Yukimi、Tamada Koji
    • Journal Title

      Molecular Cancer Therapeutics

      Volume: 21 Issue: 1 Pages: 138-148

    • DOI

      10.1158/1535-7163.mct-21-0400

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21H04808
  • [Journal Article] Enhanced anti-tumor efficacy of IL-7/CCL19-producing human CAR-T cells in orthotopic and patient-derived xenograft tumor models2021

    • Author(s)
      Goto Shunsuke、Sakoda Yukimi、Adachi Keishi、Sekido Yoshitaka、Yano Seiji、Eto Masatoshi、Tamada Koji
    • Journal Title

      Cancer Immunology, Immunotherapy

      Volume: 70 Issue: 9 Pages: 2503-2515

    • DOI

      10.1007/s00262-021-02853-3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07625, KAKENHI-PROJECT-19H03527
  • [Journal Article] Improved survival of CAR-T and tumor-specific T cells caused by anti-PD-1 scFv-producing CAR-T cells2019

    • Author(s)
      Nakajima M, Sakoda Y, Adachi K, Nagano H, Tamada K
    • Journal Title

      Cancer Sci

      Volume: 110(10) Issue: 10 Pages: 3079-3088

    • DOI

      10.1111/cas.14169

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K08646, KAKENHI-PROJECT-15H05791, KAKENHI-PROJECT-16H02474
  • [Journal Article] 腫瘍免疫研究の最前線「免疫チェックポイント阻害薬」2019

    • Author(s)
      中島正夫、佐古田幸美、玉田耕治
    • Journal Title

      大腸がんperspective

      Volume: Vol4(2) Pages: 20-25

    • Data Source
      KAKENHI-PROJECT-16H02474
  • [Journal Article] Inhibitory functions of PD-L1 and PD-L2 in the regulation of anti-tumor immunity in murine tumor microenvironment.2019

    • Author(s)
      Umezu D, Okada N, Sakoda Y, Adachi K, Ojima T, Yamaue H, Eto M, Tamada K.
    • Journal Title

      Cancer Immunology and Immunotheraoy

      Volume: 68 Issue: 2 Pages: 201-211

    • DOI

      10.1007/s00262-018-2263-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10603, KAKENHI-PROJECT-16H02474, KAKENHI-PROJECT-17H01580, KAKENHI-PROJECT-16K15623
  • [Journal Article] IL-7 and CCL19 expression in CAR-T cells improves immune cell infiltration and CAR-T cell survival in the tumor.2018

    • Author(s)
      1.Keishi Adachi, Yosuke Kano, Tomohiko Nagai, Namiko Okuyama, Yukimi Sakoda, Koji Tamada
    • Journal Title

      Nature Biotechnology

      Volume: 36(4) Issue: 4 Pages: 346-351

    • DOI

      10.1038/nbt.4086

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02474, KAKENHI-PROJECT-26830107, KAKENHI-PROJECT-16H05420
  • [Journal Article] 固形がんに対するCAR-T細胞療法の研究と開発の現状2017

    • Author(s)
      佐古田幸美、玉田耕治
    • Journal Title

      血液フロンティア

      Volume: 27(7) Pages: 59-68

    • Data Source
      KAKENHI-PROJECT-16H02474
  • [Journal Article] がん免疫療法の変遷2017

    • Author(s)
      佐古田幸美、玉田耕治
    • Journal Title

      呼吸器内科

      Volume: 32(6) Pages: 521-525

    • Data Source
      KAKENHI-PROJECT-16H02474
  • [Journal Article] Combined adjuvants of poly(I:C) plus LAG-3-Ig improve anti-tumor effects of tumor-specific T cells preventing their exhaustion.2016

    • Author(s)
      Kano Y, Iguchi T, Matsui H, Adachi K, Sakoda Y, Miyakawa T, Doi S, Hazama S, Nagano H, Ueyama Y, Tamada K.
    • Journal Title

      Cancer Sci.

      Volume: 107(4) Issue: 4 Pages: 398-406

    • DOI

      10.1111/cas.12861

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26640104, KAKENHI-PROJECT-25290057, KAKENHI-PROJECT-16H02474
  • [Journal Article] 造血器腫瘍に対するPD-L1/PD-1免疫チェックポイント阻害療法の進展2016

    • Author(s)
      奥山奈美子、佐古田幸美、玉田耕治
    • Journal Title

      血液内科

      Volume: Vol.72 No.5 Pages: 703-708

    • NAID

      40020870195

    • Data Source
      KAKENHI-PROJECT-16H02474
  • [Journal Article] Pathogenic Function of Herpesvirus Entry Mediator in Experimental Autoimmune Uveitis by Induction of Th1- and Th17-Type T Cell Responses.2016

    • Author(s)
      Sakoda Y, Nagai T, Murata S, Mizuno Y, Kurosawa H, Shoda H, Morishige N, Yanai R, Sonoda KH, Tamada K.
    • Journal Title

      J Immunol.

      Volume: 196(7) Issue: 7 Pages: 2947-54

    • DOI

      10.4049/jimmunol.1501742

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26640104, KAKENHI-PROJECT-25290057, KAKENHI-PROJECT-16H02474, KAKENHI-PROJECT-15K10869
  • [Journal Article] がん抗原の新しい概念2016

    • Author(s)
      佐古田幸美、玉田耕治
    • Journal Title

      臨床泌尿器科

      Volume: Vol.71(1) Pages: 24-29

    • Data Source
      KAKENHI-PROJECT-16H02474
  • [Journal Article] Dietary Omega-3 Fatty Acids Suppress Experimental Autoimmune Uveitis in Association with Inhibition of Th1 and Th17 Cell Function.2015

    • Author(s)
      Shoda H,Yanai R,Yoshimura T,Nagai T,Kimura K,Sobrin L,Connor KM,Sakoda Y, Tamada K,Ikeda T,Sonoda KH
    • Journal Title

      PLoS One

      Volume: 10 Issue: 9 Pages: e0138241-e0138241

    • DOI

      10.1371/journal.pone.0138241

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26462663, KAKENHI-PROJECT-26640104, KAKENHI-PROJECT-25290057
  • [Journal Article] Dietary Omega-3 Fatty Acids Suppress Experimental Autoimmune Uveitis in Association with Inhibition of Th1 and Th17 Cell Function.2015

    • Author(s)
      Shoda H,Yanai R,Yoshimura T,Nagai T,Kimura K,Sobrin L,Connor KM,Sakoda Y, Tamada K,Ikeda T,Sonoda KH
    • Journal Title

      PLoS One

      Volume: 10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K10869
  • [Journal Article] Vγ2Vδ2 T cell Costimulation Increases NK cell Killing of Monocyte-derived Dendritic Cells. Immunology.2015

    • Author(s)
      Cairo C, Surendran N, Harris KM, Mazan-Mamczarz K, Sakoda Y, Diaz-Mendez F, Tamada K, Gartenhaus RB, Mann DL, Pauza CD.
    • Journal Title

      Immunoogy

      Volume: 144 Issue: 3 Pages: 422-430

    • DOI

      10.1111/imm.12386

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25290057
  • [Journal Article] 複数のがん標的分子を認識する次世代型CAR-T細胞の研究と開発2014

    • Author(s)
      佐古田幸美、玉田耕治
    • Journal Title

      臨床血液

      Volume: 55 Pages: 1-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25290057
  • [Journal Article] T複数のがん標的分子を認識する次世代型CAR-T細胞の研究と開発2014

    • Author(s)
      佐古田幸美、玉田耕治
    • Journal Title

      臨床血液

      Volume: 55 Pages: 651-656

    • Data Source
      KAKENHI-PROJECT-25290057
  • [Presentation] 実験的自己免疫性ぶどう膜炎誘導におけるHVEM共シグナルの免疫学的制御2016

    • Author(s)
      柳井 亮二,佐古田 幸美,永井 智彦,庄田 裕美,森重 直行,園田 康平,玉田 耕治
    • Organizer
      第50回日本眼炎症学会
    • Place of Presentation
      東京都(東京国際フォーラム)
    • Year and Date
      2016-07-01
    • Data Source
      KAKENHI-PROJECT-15K10869
  • [Presentation] ω-3脂肪酸の眼炎症抑制機序におけるマクロファージの関与の検討2016

    • Author(s)
      内 翔平,柳井 亮二,陳 上,庄田 裕美,永井 智彦,佐古田 幸美,玉田 耕治,園田 康平
    • Organizer
      第50回日本眼炎症学会
    • Place of Presentation
      東京都(東京国際フォーラム)
    • Year and Date
      2016-07-01
    • Data Source
      KAKENHI-PROJECT-15K10869
  • [Presentation] ω-3脂肪酸による実験的自己免疫性ぶどう膜炎に対する炎症抑制効果2015

    • Author(s)
      庄田 裕美,柳井 亮二,木村 和博,吉村 武,Connor Kip,玉田 耕治,佐古田 幸美,池田 恒彦,園田 康平
    • Organizer
      第49回日本眼炎症学会
    • Place of Presentation
      大阪府(コンベンションセンター)
    • Year and Date
      2015-07-10
    • Data Source
      KAKENHI-PROJECT-15K10869
  • [Presentation] Omega-3 fatty acids suppress Experimental Autoimmune Uveitis by inhibiting Th1/Th17 cells.2015

    • Author(s)
      Shoda H,Yanai R,Yoshimura T,Nagai T,Kimura K,Sobrin L,Kip M Connor,Sakoda Y,Tamada K,Ikeda T,Sonoda KH
    • Organizer
      13th Congress of the International Ocular Inflammation Society
    • Place of Presentation
      USA(San Francisco)
    • Year and Date
      2015-09-29
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10869
  • 1.  TAMADA Koji (00615841)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 16 results
  • 2.  OKA Masaaki (70144946)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  YANAI Ryoji (10346554)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 4.  園田 康平 (10294943)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 5.  折田 朋子 (50467792)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  木村 和博 (60335255)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 7.  寺西 慎一郎 (90649360)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  安達 圭志 (40598611)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  城崎 幸介 (80721323)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  OJIMA Toshiyasu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  永野 浩昭
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  山上 裕機
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi