Shimoda Masafumi 下田雅史

Researcher Number	30644455
Other IDs
Affiliation (Current)	2022: 大阪大学, 大学院医学系研究科, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2022: 大阪大学, 医学系研究科, 准教授 2020: 大阪大学, 医学系研究科, 講師 2016 – 2019: 大阪大学, 医学系研究科, 助教 2015: 大阪大学, 医学(系)研究科(研究院), 助教 2014: 大阪大学, 医学(系)研究科(研究院), 特任助教(常勤)
Review Section/Research Field	Principal Investigator General surgery / Basic Section 55010:General surgery and pediatric surgery-related Except Principal Investigator Basic Section 55010:General surgery and pediatric surgery-related
Keywords	Principal Investigator 乳癌 / HER2陽性乳癌 / HER2 / TGF-beta / SMAD3 / トラスツズマブ / ラパチニブ / 癌幹細胞 / TGFβ / trastuzumab … More / 抗HER2抗体 / TGF-β / 腫瘍微小環境 / 液性免疫 / 自己抗体 / B細胞 / 形質細胞 / 濾胞性T細胞 / 腫瘍免疫 / 腫瘍浸潤B細胞 / 腫瘍浸潤形質細胞 / Neoantigen / 癌 / 免疫学 / 外科 / 高悪性度 / 血管擬態 / Focal adhesion kinase / focal adhesion kinase / 細胞内骨格 / 転移 … More Except Principal Investigator 乳癌 / エクソーム解析 / 術前化学療法 / HRD / 感受性 / 予後 / 全エクソーム解析 / 抗癌剤感受性 / 血管擬態 / 細胞運動 / 転移 / ディープラーニング Less

A search for a possible therapeutic drug targeting vasculogenic mimicry in breast cancer
- Principal Investigator
  
  増山美里
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Osaka University
血管擬態の阻害によるHER2陽性乳癌の新規治療法の開発Principal Investigator
- Principal Investigator
  
  下田雅史
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Osaka University
The development of personalized treatment for breast cancer based on genome profiling using whole exome sequence
- Principal Investigator
  
  Kim Seung Jin
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Osaka University
Association of autoantibodies to HER2 with tumor microenvironments for humoral immunity and prognosis in patients with breast cancerPrincipal Investigator
- Principal Investigator
  
  Shimoda Masafumi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
Involvement of TGF-beta/SMAD signaling in trastuzumab resistancePrincipal Investigator
- Principal Investigator
  
  Shimoda Masafumi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka University

All 2021 2020 2019 2017 2015

All Journal Article Presentation

[Journal Article] Determining homologous recombination deficiency scores with whole exome sequencing and their association with responses to neoadjuvant chemotherapy in breast cancer.2021
- Author(s)
  Kim SJ, Sota Y, Naoi Y, Honma K, Kagara N, Miyake T, Shimoda M, Tanei T, Seno S, Matsuda H, Noguchi S, Shimazu K.
- Journal Title
  
  Transl Oncol.
  
  Volume: 14 Pages: 100986-100986
- DOI
  10.1016/j.tranon.2020.100986
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02870
[Presentation] 高悪性度乳癌にみられる血管擬態を標的とする新規治療法の開発2021
- Author(s)
  増山美里、下田雅史、他
- Organizer
  第29回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08980
[Presentation] Association of autoantibodies to HER2 with tumor microenvironments for humoral immunity and prognosis in patients with breast cancer2020
- Author(s)
  Masafumi Shimoda, Yasufumi Sato, Yoshiaki Sota, Tomohiro Miyake, Tomonori Tanei, Naofumi Kagara, Yasuto Naoi, Kenzo Shimazu, Seung Jin Kim, Shinzaburo Noguchi
- Organizer
  American Association of Cancer Research Annual Meeting 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10547
[Presentation] 術前化学療法施行乳癌症例を対象としたWhole Exome SequencingによるTumor Mutational BurdenとMicrosatellite Instabilityの解析2020
- Author(s)
  草田義昭、金昇晋、加々良尚文、三宅智博、直居靖人、下田雅史、多根井智紀、島津研三、野口眞三郎
- Organizer
  日本乳癌学会
- Data Source
  KAKENHI-PROJECT-18H02870
[Presentation] 術前化学療法施行乳癌症例を対象としたWhole Exome SequencingによるHomologous Recombination Deficiency Score解析2020
- Author(s)
  金昇晋, 草田義昭, 直居靖人, 加々良尚文, 三宅智博, 下田雅史, 島津研三, 野口眞三郎
- Organizer
  日本乳癌学会
- Data Source
  KAKENHI-PROJECT-18H02870
[Presentation] HER2自己抗体高値乳癌患者における液性免疫の活性化2020
- Author(s)
  佐藤泰史、下田雅史、三宅智博、多根井智紀、加々良尚文、直居靖人、島津研三、金昇晋、野口眞三郎
- Organizer
  第28回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10547
[Presentation] HER2自己抗体高値乳癌患者における液性免疫2019
- Author(s)
  佐藤泰史、下田雅史、三宅智博、多根井智紀、加々良尚文、直居靖人、島津研三、金昇晋、野口眞三郎
- Organizer
  第27回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10547
[Presentation] 乳癌患者における HER2 自己抗体と腫瘍浸潤 B 細胞との相関2017
- Author(s)
  下田雅史
- Organizer
  第25回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10547
[Presentation] Importance of TGFβ-SMAD3 axis in resistance to anti-HER2 drugs2015
- Author(s)
  下田雅史
- Organizer
  San Antonio Breast Cancer Symposium 2015
- Place of Presentation
  San Antonio, Texas, USA
- Year and Date
  2015-12-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461945

1. Kim Seung Jin (90346213)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. 直居靖人 (30646211)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 増山美里 (30894266)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. CHIHARA Yoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Shimoda Masafumi 下田 雅史

Research Projects

Research Products

Co-Researchers

A search for a possible therapeutic drug targeting vasculogenic mimicry in breast cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

血管擬態の阻害によるHER2陽性乳癌の新規治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The development of personalized treatment for breast cancer based on genome profiling using whole exome sequence

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Association of autoantibodies to HER2 with tumor microenvironments for humoral immunity and prognosis in patients with breast cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Involvement of TGF-beta/SMAD signaling in trastuzumab resistancePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Determining homologous recombination deficiency scores with whole exome sequencing and their association with responses to neoadjuvant chemotherapy in breast cancer.2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] 高悪性度乳癌にみられる血管擬態を標的とする新規治療法の開発2021

Author(s)

Organizer

Data Source

[Presentation] Association of autoantibodies to HER2 with tumor microenvironments for humoral immunity and prognosis in patients with breast cancer2020

Author(s)

Organizer

Data Source

[Presentation] 術前化学療法施行乳癌症例を対象としたWhole Exome SequencingによるTumor Mutational BurdenとMicrosatellite Instabilityの解析2020

Author(s)

Organizer

Data Source

[Presentation] 術前化学療法施行乳癌症例を対象としたWhole Exome SequencingによるHomologous Recombination Deficiency Score解析2020

Author(s)

Organizer

Data Source

[Presentation] HER2自己抗体高値乳癌患者における液性免疫の活性化2020

Author(s)

Organizer

Data Source

[Presentation] HER2自己抗体高値乳癌患者における液性免疫2019

Author(s)

Organizer

Data Source

[Presentation] 乳癌患者における HER2 自己抗体と腫瘍浸潤 B 細胞との相関2017

Author(s)

Organizer

Data Source

[Presentation] Importance of TGFβ-SMAD3 axis in resistance to anti-HER2 drugs2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Shimoda Masafumi 下田雅史