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Shimoda Masafumi  下田 雅史

ORCIDConnect your ORCID iD *help
Researcher Number 30644455
Other IDs
Affiliation (Current) 2022: 大阪大学, 大学院医学系研究科, 准教授
Affiliation (based on the past Project Information) *help 2021 – 2022: 大阪大学, 医学系研究科, 准教授
2020: 大阪大学, 医学系研究科, 講師
2016 – 2019: 大阪大学, 医学系研究科, 助教
2015: 大阪大学, 医学(系)研究科(研究院), 助教
2014: 大阪大学, 医学(系)研究科(研究院), 特任助教(常勤)
Review Section/Research Field
Principal Investigator
General surgery / Basic Section 55010:General surgery and pediatric surgery-related
Except Principal Investigator
Basic Section 55010:General surgery and pediatric surgery-related
Keywords
Principal Investigator
乳癌 / HER2陽性乳癌 / HER2 / TGF-beta / SMAD3 / トラスツズマブ / ラパチニブ / 癌幹細胞 / TGFβ / trastuzumab … More / 抗HER2抗体 / TGF-β / 腫瘍微小環境 / 液性免疫 / 自己抗体 / B細胞 / 形質細胞 / 濾胞性T細胞 / 腫瘍免疫 / 腫瘍浸潤B細胞 / 腫瘍浸潤形質細胞 / Neoantigen / 癌 / 免疫学 / 外科 / 高悪性度 / 血管擬態 / Focal adhesion kinase / focal adhesion kinase / 細胞内骨格 / 転移 … More
Except Principal Investigator
乳癌 / エクソーム解析 / 術前化学療法 / HRD / 感受性 / 予後 / 全エクソーム解析 / 抗癌剤感受性 / 血管擬態 / 細胞運動 / 転移 / ディープラーニング Less
  • Research Projects

    (5 results)
  • Research Products

    (9 results)
  • Co-Researchers

    (4 People)
  •  A search for a possible therapeutic drug targeting vasculogenic mimicry in breast cancer

    • Principal Investigator
      増山 美里
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Osaka University
  •  血管擬態の阻害によるHER2陽性乳癌の新規治療法の開発Principal Investigator

    • Principal Investigator
      下田 雅史
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Osaka University
  •  The development of personalized treatment for breast cancer based on genome profiling using whole exome sequence

    • Principal Investigator
      Kim Seung Jin
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Osaka University
  •  Association of autoantibodies to HER2 with tumor microenvironments for humoral immunity and prognosis in patients with breast cancerPrincipal Investigator

    • Principal Investigator
      Shimoda Masafumi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Osaka University
  •  Involvement of TGF-beta/SMAD signaling in trastuzumab resistancePrincipal Investigator

    • Principal Investigator
      Shimoda Masafumi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Osaka University

All 2021 2020 2019 2017 2015

All Journal Article Presentation

  • [Journal Article] Determining homologous recombination deficiency scores with whole exome sequencing and their association with responses to neoadjuvant chemotherapy in breast cancer.2021

    • Author(s)
      Kim SJ, Sota Y, Naoi Y, Honma K, Kagara N, Miyake T, Shimoda M, Tanei T, Seno S, Matsuda H, Noguchi S, Shimazu K.
    • Journal Title

      Transl Oncol.

      Volume: 14 Pages: 100986-100986

    • DOI

      10.1016/j.tranon.2020.100986

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02870
  • [Presentation] 高悪性度乳癌にみられる血管擬態を標的とする新規治療法の開発2021

    • Author(s)
      増山美里、下田雅史、他
    • Organizer
      第29回日本乳癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K08980
  • [Presentation] Association of autoantibodies to HER2 with tumor microenvironments for humoral immunity and prognosis in patients with breast cancer2020

    • Author(s)
      Masafumi Shimoda, Yasufumi Sato, Yoshiaki Sota, Tomohiro Miyake, Tomonori Tanei, Naofumi Kagara, Yasuto Naoi, Kenzo Shimazu, Seung Jin Kim, Shinzaburo Noguchi
    • Organizer
      American Association of Cancer Research Annual Meeting 2020
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10547
  • [Presentation] 術前化学療法施行乳癌症例を対象としたWhole Exome SequencingによるTumor Mutational BurdenとMicrosatellite Instabilityの解析2020

    • Author(s)
      草田義昭、金昇晋、加々良尚文、三宅智博、直居靖人、下田雅史、多根井智紀、島津研三、野口眞三郎
    • Organizer
      日本乳癌学会
    • Data Source
      KAKENHI-PROJECT-18H02870
  • [Presentation] 術前化学療法施行乳癌症例を対象としたWhole Exome SequencingによるHomologous Recombination Deficiency Score解析2020

    • Author(s)
      金昇晋, 草田義昭, 直居靖人, 加々良尚文, 三宅智博, 下田雅史, 島津研三, 野口眞三郎
    • Organizer
      日本乳癌学会
    • Data Source
      KAKENHI-PROJECT-18H02870
  • [Presentation] HER2自己抗体高値乳癌患者における液性免疫の活性化2020

    • Author(s)
      佐藤泰史、下田雅史、三宅智博、多根井智紀、加々良尚文、直居靖人、島津研三、金昇晋、野口眞三郎
    • Organizer
      第28回日本乳癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K10547
  • [Presentation] HER2自己抗体高値乳癌患者における液性免疫2019

    • Author(s)
      佐藤泰史、下田雅史、三宅智博、多根井智紀、加々良尚文、直居靖人、島津研三、金昇晋、野口眞三郎
    • Organizer
      第27回日本乳癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K10547
  • [Presentation] 乳癌患者における HER2 自己抗体と腫瘍浸潤 B 細胞との相関2017

    • Author(s)
      下田雅史
    • Organizer
      第25回日本乳癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K10547
  • [Presentation] Importance of TGFβ-SMAD3 axis in resistance to anti-HER2 drugs2015

    • Author(s)
      下田雅史
    • Organizer
      San Antonio Breast Cancer Symposium 2015
    • Place of Presentation
      San Antonio, Texas, USA
    • Year and Date
      2015-12-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461945
  • 1.  Kim Seung Jin (90346213)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 2.  直居 靖人 (30646211)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  増山 美里 (30894266)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  CHIHARA Yoko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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