Hayata Manabu 早田学

Researcher Number	30646120
Other IDs
Affiliation (based on the past Project Information) *help	2019 – 2023: 熊本大学, 病院, 助教 2018: 熊本大学, 医学部附属病院, 病院教員 2015 – 2017: 熊本大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Kidney internal medicine Except Principal Investigator Basic Section 55060:Emergency medicine-related
Keywords	Principal Investigator CKD / AKI / 慢性腎臓病 / 急性腎障害 / 内科 / マクロファージ / 慢性炎症 Except Principal Investigator Infection / Ｉｎｆｌａｍｍａｔｉｏｎ / ｍｉｃｒｏＲＮＡ … More / Ｓｅｐｓｉｓ / Innate Immunity / 敗血症 / PDCD-4 / PTEN / PDCD4 / miR-21 / inflammation / microRNA-21 / Inflammation / SIRS / Sepsis / microRNA Less

Inovation of diagnosis and treatment for the regulation of sepsis by microRNA-21.
- Principal Investigator
  
  Kamohara Hidenobu
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Tokyo Medical University
  Kumamoto University
Elucidation of the role of homeostatic inflammation in the AKI to CKD transition mechanism focusing on the time phase changesPrincipal Investigator
- Principal Investigator
  
  Hayata Manabu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kumamoto University
The role of chronic inflammation on renal recovery after AKIPrincipal Investigator
- Principal Investigator
  
  Hayata Manabu
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kumamoto University

All 2019 2018 2017 2016 2015 2014

All Journal Article Presentation Book

[Book] CKDと脂質異常症―脂肪毒性の役割―2016
- Author(s)
  早田学、桒原孝成、向山政志
- Publisher
  最新医学社
- Data Source
  KAKENHI-PROJECT-15K19459
[Book] 腎と透析2015
- Author(s)
  早田学、桒原孝成、向山政志
- Publisher
  東京医学社
- Data Source
  KAKENHI-PROJECT-15K19459
[Journal Article] Circulating angiopoietin-like protein 2 levels and mortality risk in patients receiving maintenance hemodialysis: a prospective cohort study2019
- Author(s)
  Morinaga J, Kakuma T, Fukami H, Hayata M, Uchimura K, Mizumoto T, Kakizoe Y, Miyoshi T, Shiraishi N, Adachi M, Izumi Y, Kuwabara T, Okadome Y, Sato M, Horiguchi H, Sugizaki T, Kadomatsu T, Miyata K, Tajiri S, Tajiri T, Tomita K, Kitamura K, Oike Y, Mukoyama M.
- Journal Title
  
  Nephrology Dialysis Transplantation
  
  Volume: 印刷中 Issue: 5 Pages: 854-860
- DOI
  10.1093/ndt/gfz236
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08247, KAKENHI-PROJECT-19K08560, KAKENHI-PROJECT-19K08728, KAKENHI-PROJECT-19K17607, KAKENHI-PROJECT-18H02809, KAKENHI-PROJECT-17K09704, KAKENHI-PROJECT-17K09705, KAKENHI-PROJECT-17K09706, KAKENHI-PROJECT-19K08729, KAKENHI-PROJECT-20K08611
[Journal Article] Refractory peritonitis by spontaneous perforation of the common bile duct in a patient receiving peritoneal dialysis2017
- Author(s)
  Manabu Hayata, Junji Yamashita, Kentaro Tokunaga, Masashi Ejima, Katsuyuki Sagishima, Shigeki Nakagawa, Daisuke Hashimoto, Hideo Baba, Kosuke Maruyama, Yu Kohrogi, Teruhiko Mizumoto, Masashi Mukoyama and Hidenobu Kamohara
- Journal Title
  
  Renal Replacement Therapy
  
  Volume: 3: 53 Pages: 1-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09704
[Journal Article] A serine protease inhibitor attenuates aldosterone-induced kidney injuries via the suppression of plasmin activity.2016
- Author(s)
  Y. Kakizoe, Y. Miyasato, T. Onoue, T. Nakagawa, M. Hayata, K. Uchimura, J. Morinaga, T. Mizumoto, M. Adachi, T. Miyoshi, Y. Sakai, K. Tomita, M. Mukoyama, K. Kitamura
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 132 Issue: 2 Pages: 145-153
- DOI
  10.1016/j.jphs.2016.09.005
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461226, KAKENHI-PROJECT-15K19459, KAKENHI-PROJECT-15K19460
[Journal Article] Mild systemic thermal therapy ameliorates renal dysfunction in a rodent model of chronic kidney disease.2016
- Author(s)
  Iwashita Y, Kuwabara T, Hayata M, Kakizoe Y, Izumi Y, Iiyama J, Kitamura K, Mukoyama M.
- Journal Title
  
  Am J Physiol Renal Physiol.
  
  Volume: in press Issue: 11 Pages: 1-1
- DOI
  10.1152/ajprenal.00519.2015
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09268, KAKENHI-PROJECT-26461234, KAKENHI-PROJECT-15K19459, KAKENHI-PROJECT-26461226, KAKENHI-PROJECT-15K01406, KAKENHI-PROJECT-16K19493
[Journal Article] Combination therapy with renin-angiotensin-aldosterone system inhibitor telmisartan and serine protease inhibitor camostat mesilate provides further renoprotection in a rat chronic kidney disease model.2016
- Author(s)
  Yuki Narita, Miki Ueda, Kohei Uchimura, Yutaka Kakizoe, Yoshikazu Miyasato, Teruhiko Mizumoto, Jun Morinaga, Manabu Hayata, Terumasa Nakagawa, Masataka Adachi, Taku Miyoshi, Yoshiki Sakai, Daisuke Kadowaki, Sumio Hirata, Masashi Mukoyama, Kenichiro Kitamura
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 130 Issue: 2 Pages: 110-116
- DOI
  10.1016/j.jphs.2016.01.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461226, KAKENHI-PROJECT-26461234, KAKENHI-PROJECT-15K19459, KAKENHI-PROJECT-15K19460, KAKENHI-PROJECT-15K08100
[Journal Article] The serine protease inhibitor camostat mesilate attenuates the progression of chronic kidney disease through its antioxidant effects.2015
- Author(s)
  Miki Ueda, Kohei Uchimura, Yuki Narita, Yoshikazu Miyasato, Teruhiko Mizumoto, Jun Morinaga, Manabu Hayata, Yutaka Kakizoe, Masataka Adachi, Taku Miyoshi, Naoki Shiraishi, Daisuke Kadowaki, Y Sakai, Masashi Mukoyama, Kenichiro Kitamura
- Journal Title
  
  Nephron
  
  Volume: 129 Issue: 3 Pages: 223-232
- DOI
  10.1159/000375308
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461226, KAKENHI-PROJECT-26461234, KAKENHI-PROJECT-15K19459, KAKENHI-PROJECT-15K19460
[Journal Article] Low-density lipoprotein apheresis for proteinuria in lupus nephritis with intraglomerular foam cells containing cholesterol crystals.2014
- Author(s)
  Shiraishi N, Kitamura K, Hayata M, Ogata T, Tajiri-Okamura K, Nakayama Y, Kohda Y, Tomita K, Mukoyama M.
- Journal Title
  
  Am J Kidney Dis.
  
  Volume: 65 Issue: 3 Pages: 490-493
- DOI
  10.1053/j.ajkd.2014.09.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591206, KAKENHI-PROJECT-26461233, KAKENHI-PROJECT-15K19459
[Presentation] CKDにおけるMRP8の化学修飾の探索とその意義の検討2018
- Author(s)
  神吉智子, 桑原孝成, 梅本周朗, 藤本大介, 水本輝彦, 早田学, 中山憲司, 宮崎有, 井上貴博, 小川修, 向山政志
- Organizer
  日本腎臓学会
- Data Source
  KAKENHI-PROJECT-17K09704
[Presentation] 糸球体内クロストークにおけるメサンギウム細胞由来因子によるポドサイトERストレス応答の検討2018
- Author(s)
  藤本大介, 桑原孝成, 梅本周朗, 神吉智子, 水本輝彦, 早田学, 泉裕一郎, 柿添豊, 向山政志
- Organizer
  日本腎臓学会
- Data Source
  KAKENHI-PROJECT-17K09704
[Presentation] 抗酒薬シアナマイドによる汎血球減少から壊死性筋膜炎および敗血症性ショックを来した一例2017
- Author(s)
  早田学、徳永健太郎、江嶋正志、鷺島克之、蒲原英伸
- Organizer
  第1回日本集中治療医学会九州支部学術集会
- Data Source
  KAKENHI-PROJECT-17K09704
[Presentation] 当院で実施した心停止後症候群に対する体温管理療法2017
- Author(s)
  早田学、中原智史、徳永健太郎、江嶋正志、成松紀子、鷺島克之、蒲原英伸
- Organizer
  第20回日本脳低温療法・体温管理学会
- Data Source
  KAKENHI-PROJECT-17K09704
[Presentation] Doxycycline ameliorates cisplatin-induced nephrotoxicity in mice through directly acting on proximal tubular cells and promoting cell viability.2016
- Author(s)
  Terumasa Nakagawa, Yutaka Kakizoe, Naoki Suenaga, Yuki Narita, Yoshikazu Miyasato, Teruhiko Mizumoto, Manabu Hayata, Yuichiro Izumi, Takashige Kuwabara, Masataka Adachi, Hirofumi Jono, Hideyuki Saito, Kenichiro Kitamura, Masashi Mukoyama.
- Organizer
  American Society of Nephrology Kidney Week 2016
- Place of Presentation
  Chicago, IL
- Year and Date
  2016-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19459
[Presentation] Intraglomerular crosstalk between mesangial cells and macrophages in glomerular injury.2016
- Author(s)
  Shuro Umemoto, Takashige Kuwabara, Manabu Hayata, Daisuke Fujimoto, Tomoko Kanki, Yuichiro Izumi, Yutaka Kakizoe, Masashi Mukoyama.
- Organizer
  American Society of Nephrology Kidney Week 2016
- Place of Presentation
  Chicago, IL
- Year and Date
  2016-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19459
[Presentation] The role of activated renin-angiotensin system for the MRP8/TLR4 signaling in diabetic nephropathy.2016
- Author(s)
  Shuro Umemoto, Takashige Kuwabara, Hirotaka Imamaki, Manabu Hayata, Yuichiro Izumi, Yutaka Kakizoe, Kiyoshi Mori, Masashi Mukoyama.
- Organizer
  The 26th Scientific Meeting of the International Society of Hypertension
- Place of Presentation
  Seoul, Korea
- Year and Date
  2016-09-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19459
[Presentation] Myeloid-specific deletion of MRP8 ameliorates glomerulonephritis through affecting macrophage characterization.2016
- Author(s)
  Kuwabara Takashige, Kiyoshi Mori, Manabu Hayata, Shuro Umemoto, Hideki Yokoi, Masashi Mukoyama.
- Organizer
  American Society of Nephrology Kidney Week 2016
- Place of Presentation
  Chicago, IL
- Year and Date
  2016-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19459
[Presentation] メタボリックシンドロームモデルラットのポドサイト障害におけるセリンプロテアーゼの役割2015
- Author(s)
  早田　学、水本　輝彦、宮里　賢和、内村　幸平、森永　潤、柿添　豊、酒井　芳紀、向山　政志、北村　健一郎
- Organizer
  第58回日本腎臓学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-06-07
- Data Source
  KAKENHI-PROJECT-15K19459

1. Kamohara Hidenobu (90398222)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 桑原孝成 (00393356)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. 江嶋正志 (20718316)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 鷺島克之 (40336235)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 徳永健太郎 (50751335)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. IZUMI Yuichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 森潔

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
8. 向山政志

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
9. 北村健一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hayata Manabu 早田 学

Research Projects

Research Products

Co-Researchers

Inovation of diagnosis and treatment for the regulation of sepsis by microRNA-21.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the role of homeostatic inflammation in the AKI to CKD transition mechanism focusing on the time phase changesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of chronic inflammation on renal recovery after AKIPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] CKDと脂質異常症―脂肪毒性の役割―2016

Author(s)

Publisher

Data Source

[Book] 腎と透析2015

Author(s)

Publisher

Data Source

[Journal Article] Circulating angiopoietin-like protein 2 levels and mortality risk in patients receiving maintenance hemodialysis: a prospective cohort study2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Refractory peritonitis by spontaneous perforation of the common bile duct in a patient receiving peritoneal dialysis2017

Author(s)

Journal Title

Data Source

[Journal Article] A serine protease inhibitor attenuates aldosterone-induced kidney injuries via the suppression of plasmin activity.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mild systemic thermal therapy ameliorates renal dysfunction in a rodent model of chronic kidney disease.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Combination therapy with renin-angiotensin-aldosterone system inhibitor telmisartan and serine protease inhibitor camostat mesilate provides further renoprotection in a rat chronic kidney disease model.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The serine protease inhibitor camostat mesilate attenuates the progression of chronic kidney disease through its antioxidant effects.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Low-density lipoprotein apheresis for proteinuria in lupus nephritis with intraglomerular foam cells containing cholesterol crystals.2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] CKDにおけるMRP8の化学修飾の探索とその意義の検討2018

Author(s)

Organizer

Data Source

[Presentation] 糸球体内クロストークにおけるメサンギウム細胞由来因子によるポドサイトERストレス応答の検討2018

Author(s)

Organizer

Data Source

[Presentation] 抗酒薬シアナマイドによる汎血球減少から壊死性筋膜炎および敗血症性ショックを来した一例2017

Author(s)

Organizer

Data Source

[Presentation] 当院で実施した心停止後症候群に対する体温管理療法2017

Author(s)

Organizer

Data Source

Hayata Manabu 早田学