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Kaku Masami  角 正美

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KAKU Masami  角 正美

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Researcher Number 30646261
Affiliation (Current) 2025: 植草学園大学, 保健医療学部, 教授
Affiliation (based on the past Project Information) *help 2018 – 2019: 植草学園大学, 保健医療学部, 講師
2013 – 2017: 茨城県立医療大学, 保健医療学部, 嘱託助手
2014: 茨城県立医療大学, 保健医療学部, 助手
Review Section/Research Field
Principal Investigator
Rehabilitation science/Welfare engineering / Kansei informatics
Except Principal Investigator
Rehabilitation science/Welfare engineering / Neurophysiology / General neuroscience
Keywords
Principal Investigator
ラット / 社会的孤立 / アルツハイマー病 / 記憶保持能力 / シナプス機能障害 / 非薬物的介入 / 脳内ストレス応答 / 閉じこもり / 自発運動 / 認知記憶障害 … More / 習慣的運動 / 認知機能障害 / アルツハイマー病モデルラット / 運動の質 / 参照記憶 / アミロイドβ蛋白質 / Barnes迷路 / BDNF / 逆転学習 / 強制的運動 / 自発的運動 / ストレス / 参照記憶障害 … More
Except Principal Investigator
行動解析 / GFP / トランスジェニックマウス / オリゴマー / シナプス / アミロイドβタンパク質 / アルツハイマー病 / 老化 / 脳神経疾患 / 神経科学 / 習慣的運動 / 運動 / 長期増強 Less
  • Research Projects

    (4 results)
  • Research Products

    (15 results)
  • Co-Researchers

    (4 People)
  •  Behavioral and electrophysiological analyses of new Alzheimer's disease model mouse that express amyloid beta oligomer intraneuronally

    • Principal Investigator
      OCHIISHI TOMOYO
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Rehabilitation science/Welfare engineering
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  To elucidate the brain mechanisms of non-pharmacological treatment of cognitive impairment in Alzheimer's disease.Principal Investigator

    • Principal Investigator
      Kaku Masami
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Rehabilitation science/Welfare engineering
    • Research Institution
      Uekusa Gakuen University
      Ibaraki Prefectural University of Health Science
  •  Development of new amyloid beta-GFP fusion protein which is a useful tool for the analysis of the synaptic function of amyloid beta monomers and oligomers

    • Principal Investigator
      OCHIISHI TOMOYO
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurophysiology / General neuroscience
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  Influence of the isolation rearing or the type of exercise on cognitive function in alzheimer's disease model rats.Principal Investigator

    • Principal Investigator
      Kaku Masami
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Kansei informatics
    • Research Institution
      Ibaraki Prefectural University of Health Science

All 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

  • [Journal Article] New Alzheimer’s disease model mouse specialized for analyzing the function and toxicity of intraneuronal Amyloid β oligomers2019

    • Author(s)
      Ochiishi Tomoyo、Kaku Masami、Kiyosue Kazuyuki、Doi Motomichi、Urabe Takao、Hattori Nobutaka、Shimura Hideki、Ebihara Tatsuhiko
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 17368-17368

    • DOI

      10.1038/s41598-019-53415-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K11362, KAKENHI-PROJECT-16K16434
  • [Presentation] Characteristic features of new Alzheimer’s disease model mouse that express amyloid β oligomer intraneuronally.2019

    • Author(s)
      Tomoyo Ochiishi, Masami Kaku, Kazuyuki Kiyosue, Motomichi Doi, Tatsuhiko Ebihara
    • Organizer
      第42回日本分子生物学学会年会
    • Data Source
      KAKENHI-PROJECT-16K16434
  • [Presentation] Behavioral and electrophysiological analyses of new Alzheimer’s model mouse that express amyloid β oligomer intraneuronally.2018

    • Author(s)
      Tomoyo Ochiishi, Masami Kaku, Kazuyuki Kiyosue, Motomichi Doi, Tatsuhiko Ebihara
    • Organizer
      Neuroscience 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K12944
  • [Presentation] Behavioral and electrophysiological analysis of the Alzheimer’s model mouse the express amyloid β oligomer.2017

    • Author(s)
      落石知世、清末 和之、戸井 基道、海老原 達彦、角正美
    • Organizer
      生命科学系学会合同年次大会
    • Data Source
      KAKENHI-PROJECT-16K12944
  • [Presentation] Volantary exercise facilitates acquisition and reversal learning of rats in the Barnes maze task.2016

    • Author(s)
      Masami Kaku
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      横浜
    • Year and Date
      2016-07-20
    • Data Source
      KAKENHI-PROJECT-25870587
  • [Presentation] アミロイドβオリゴマーを発現する新規アルツハイマーモデルマウスの解析2016

    • Author(s)
      落石知世、角正美、清末和之、志村秀樹、卜部貴夫、服部信孝、戸井基道、海老原達彦
    • Organizer
      第35回日本認知症学会学術集会
    • Place of Presentation
      東京国際フォーラム(東京都)
    • Year and Date
      2016-12-02
    • Data Source
      KAKENHI-PROJECT-16K12944
  • [Presentation] Behavioral and electrophysiological analysis of the Alzheimer’s disease model mouse that express amyloid β oligomer intraneuronally.2016

    • Author(s)
      Tomoyo Ochiishi, Kazuyuki Kiyosue, Masami Kaku, Motomichi Doi, Tatsuhiko Ebihara
    • Organizer
      第39回日本神経科学学会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Year and Date
      2016-07-21
    • Data Source
      KAKENHI-PROJECT-16K12944
  • [Presentation] Voluntary Exercise Facilitates Acquisition and Reversal Learning of Rats in the Barnes Maze Task.2016

    • Author(s)
      角正美、角友起、八島康太郎、落石知世、永田博司
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      横浜
    • Year and Date
      2016-07-20
    • Data Source
      KAKENHI-PROJECT-16K16434
  • [Presentation] Continuous intraventrivular infusion of β-amyloid protein causes spatial and nonspatial reference memory deficit in rats.2015

    • Author(s)
      Masami Kaku
    • Organizer
      第38回日本神経科学大会
    • Place of Presentation
      神戸
    • Year and Date
      2015-07-28
    • Data Source
      KAKENHI-PROJECT-25870587
  • [Presentation] Physiological and behavioral roles of intracellular amyloid β oligomer in a novel amyloid β protein transgenic mouse.2015

    • Author(s)
      Tomoyo Ochiishi, Masami Kaku, Kazuhiko Yamasaki, Motomichi Doi, Tatsuhiko Ebihara
    • Organizer
      第38回日本神経科学大会
    • Place of Presentation
      神戸国際会議場(兵庫県)
    • Year and Date
      2015-07-28
    • Data Source
      KAKENHI-PROJECT-26640023
  • [Presentation] Isolation rearing hastens the onset of reference memory deficit in β-amyloid protein infused rats.2014

    • Author(s)
      Masami Kaku, Kazuo Yamada, Yukio Ichitani, Hiroshi Nagata
    • Organizer
      第37回日本神経科学大会
    • Place of Presentation
      神奈川
    • Data Source
      KAKENHI-PROJECT-25870587
  • [Presentation] Reference memory deficit in AD may induce disorientation to place: analysis of residential maze behavior in β-amyloid protein infused rats.2013

    • Author(s)
      Masami Kaku, Kazuo Yamada, Yukio Ichitani, Hiroshi Nagata
    • Organizer
      第36回日本神経科学大会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-25870587
  • [Presentation] 脳内βアミロイドの蓄積はラットの居住型迷路における参照記憶障害を引き起こす2013

    • Author(s)
      角正美、山田一夫、一谷幸男、永田博司
    • Organizer
      日本動物心理学会73回大会
    • Place of Presentation
      茨城
    • Data Source
      KAKENHI-PROJECT-25870587
  • [Presentation] Continuous intraventricular infusion of β-amyloid protein causes spatial and non-spatial reference memory deficit in rats.

    • Author(s)
      角正美、古家宏樹、角友起、永田博司
    • Organizer
      第38回日本神経科学大会
    • Place of Presentation
      神戸
    • Year and Date
      2015-07-28 – 2015-07-31
    • Data Source
      KAKENHI-PROJECT-25870587
  • [Presentation] Isolation rearing hastens the onset of reference memory deficit in β-amyloid protein infused rats.

    • Author(s)
      角正美、山田一夫、一谷幸男、永田博司
    • Organizer
      第37回日本神経科学大会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-11 – 2014-09-13
    • Data Source
      KAKENHI-PROJECT-25870587
  • 1.  OCHIISHI TOMOYO (30356729)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 2.  EBIHARA Tatsuhiko (00344119)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 3.  DOI Motomichi (50344213)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  Kiyosue Kazuyuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results

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