HORAI Yoshiro 寶來吉朗

… Alternative Names

HORAI YOSHIRO 寶來吉朗

寳來吉朗ホウライヨシロウ

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Researcher Number	30646782
Other IDs
External Links
Affiliation (Current)	2025: 長崎大学, 医歯薬学総合研究科(医学系), 客員研究員
Affiliation (based on the past Project Information) *help	2022 – 2023: 長崎大学, 医歯薬学総合研究科(医学系), 客員研究員 2017 – 2021: 独立行政法人国立病院機構(長崎医療センター臨床研究センター), 臨床研究センター, 自己免疫研究室長 2015: 長崎大学, 病院(医学系), 医員 2014: 長崎大学, 病院(医学系), 研究員 2013: 長崎大学, 大学病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related / Collagenous pathology/Allergology Except Principal Investigator Collagenous pathology/Allergology
Keywords	Principal Investigator long non-coding RNA / シェーグレン症候群 / 免疫学 / NFATｃ１ / PIM-1 / NFATc1 / NRON Except Principal Investigator アポトーシス / RANTES / IP-10 … More / ICAM-１ / 膠原病 / HTLV-I / シェーグレン症候群 Less

LncRNAと関連分子の包括的解析によるシェーグレン症候群病態解明と治療標的同定Principal Investigator
- Principal Investigator
  
  寶來吉朗
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Nagasaki University
LncRNA in labial salivary glands of Sjogren's syndrome patientsPrincipal Investigator
- Principal Investigator
  
  HORAI Yoshiro
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Department of Clinical Research, National Hospital Organization Nagasaki Medical Center
Elucidation of mechanism for HTLV-I-associated Sjogren's syndrome
- Principal Investigator
  
  NAKAMURA Hideki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Nagasaki University

All 2024 2023 2022 2021 2020 2019 2018 2017 2015 Other

All Journal Article Presentation Book

[Book] シェーグレン症候群の診断と治療マニュアル(第4章臨床症状 2.腺外症状 7 原発性シェーグレン症候群の筋・骨格系徴候；筋・関節病変)2018
- Author(s)
  日本シェーグレン症候群学会(分担執筆者寶來吉朗)
- Publisher
  診断と治療社
- ISBN
  9784787823694
- Data Source
  KAKENHI-PROJECT-17K16210
[Journal Article] Human leucocyte antigens and Japanese patients with polymyalgia rheumatica: the protective effect of<i>DRB1*09:01</i>2024
- Author(s)
  Nogi Shinichi、Oka Shomi、Higuchi Takashi、Furukawa Hiroshi、Shimada Kota、Azuma Takanori、Sugiyama Takao、Hirano Fuminori、Okamoto Akira、Fujimori Misuzu、Horai Yoshiro、Ihata Atsushi、Hashimoto Atsushi、Komiya Akiko、Matsui Toshihiro、Fukui Naoshi、Katayama Masao、Migita Kiyoshi、Tohma Shigeto
- Journal Title
  
  RMD Open
  
  Volume: 10 Issue: 1 Pages: e003897-e003897
- DOI
  10.1136/rmdopen-2023-003897
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16352, KAKENHI-PROJECT-23K06879
[Journal Article] Takayasu’s arteritis after a prolonged course of hypertrophic osteoarthropathy2023
- Author(s)
  Jubashi Takashi、Horai Yoshiro、Tomokawa Takuya、Hara Kazusato、Kawakami Atsushi
- Journal Title
  
  Modern Rheumatology Case Reports
  
  Volume: 8 Issue: 1 Pages: 107-111
- DOI
  10.1093/mrcr/rxad042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16352
[Journal Article] Current Views on Pathophysiology and Potential Therapeutic Targets in Sjoegren’s Syndrome: A Review from the Perspective of Viral Infections, Toll-like Receptors, and Long-Noncoding RNAs2023
- Author(s)
  Horai Yoshiro、Shimizu Toshimasa、Umeda Masataka、Nishihata Shin-Ya、Nakamura Hideki、Kawakami Atsushi
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 12 Issue: 18 Pages: 5873-5873
- DOI
  10.3390/jcm12185873
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16352
[Journal Article] Comparison of complications during 1-year follow-up between remitting seronegative symmetrical synovitis with pitting edema syndrome and elderly-onset rheumatoid arthritis2022
- Author(s)
  Origuchi Tomoki、Umeda Masataka、Koga Tomohiro、Kawashiri Shin-ya、Iwamoto Naoki、Ichinose Kunihiro、Tamai Mami、Tsukada Toshiaki、Miyashita Taiichiro、Iwanaga Nozomi、Horai Yoshiro、Arima Kazuhiko、Aramaki Toshiyuki、Ueki Yukitaka、Eguchi Katsumi、Kawakami Atsushi
- Journal Title
  
  Immunological Medicine
  
  Volume: - Issue: 3 Pages: 1-7
- DOI
  10.1080/25785826.2022.2046307
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08439, KAKENHI-PROJECT-21K20905, KAKENHI-PROJECT-22K16352, KAKENHI-PROJECT-22K16362
[Journal Article] Clinical analysis of gender and pre-existing diabetes mellitus in patients with polymyalgia rheumatica: A retrospective study in a Japanese population2022
- Author(s)
  Horai Yoshiro、Otsuka Mizuna、Kawahara Chieko、Iwanaga Nozomi、Yamasaki Yusuke、Watanobe Taro、Yasui Junichi、Saishoji Yusuke、Torisu Yuichi、Mori Takahiro、Mori Hideki、Izumi Yasumori、Kawakami Atsushi
- Journal Title
  
  Modern Rheumatology
  
  Volume: 33 Issue: 1 Pages: 182-186
- DOI
  10.1093/mr/roac012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16352
[Journal Article] Clinical Characteristics of Patients With IgG4-Related Disease Complicated by Hypocomplementemia2022
- Author(s)
  Fujita Yuya、Fukui Shoichi、Umeda Masataka、Tsuji Sosuke、Iwamoto Naoki、Nakashima Yoshikazu、Horai Yoshiro、Suzuki Takahisa、Okada Akitomo、Aramaki Toshiyuki、Ueki Yukitaka、Mizokami Akinari、Origuchi Tomoki、Watanabe Hiroshi、Migita Kiyoshi、Kawakami Atsushi
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 13 Pages: 828122-828122
- DOI
  10.3389/fimmu.2022.828122
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16210, KAKENHI-PROJECT-21K08439, KAKENHI-PROJECT-21K20905
[Journal Article] Comparison of the quantitative measurement of 18F-FDG PET/CT and histopathological findings in IgG4-related disease.2021
- Author(s)
  Tsuji S, Iwamoto N, Horai Y, et al.
- Journal Title
  
  Clin Exp Rheumatol.
  
  Volume: 39 Pages: 1338-1344
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16210
[Journal Article] Increased Expression of the lncRNA NRON Along With NFATc1/PIM-1 in Labial Salivary Glands of Sj?gren’s Syndrome Patients2021
- Author(s)
  Horai Yoshiro、Nakamura Hideki、Shimizu Toshimasa、Nishihata Shinya、Iwamoto Naoki、Kuroki Tamotsu、Okano Shinji、Kawakami Atsushi
- Journal Title
  
  Applied Immunohistochemistry & Molecular Morphology
  
  Volume: 29 Issue: 10 Pages: 734-740
- DOI
  10.1097/pai.0000000000000959
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16210
[Journal Article] Development of hypocomplementemic urticarial vasculitis during certolizumab pegol treatment for rheumatoid arthritis: A case report2020
- Author(s)
  Horai Yoshiro、Ishikawa Hiroshi、Iwanaga Nozomi、Izumi Yasumori、Matsuoka Yuki、Miura Shiro、Kawakami Atsushi
- Journal Title
  
  Journal of Clinical Pharmacy and Therapeutics
  
  Volume: 45 Issue: 5 Pages: 1179-1182
- DOI
  10.1111/jcpt.13117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16210
[Journal Article] Rheumatoid arthritis patients with low baseline Health Assessment Questionnaire scores have a risk of functional disability progression: a post hoc analysis of a nationwide longitudinal cohort in Japan2020
- Author(s)
  Sumiyoshi, R., Hidaka, T., Koga, T., Okada, A., Fukuda, T., Ishii, T., Ueki, Y., Kodera, T., Nakashima, M., Takahashi, Y., Honda, S., Horai, Y., Watanabe, R., Okuno, H., Aramaki, T., Izumiyama, T., Takai, O., Miyashita, T., Kawashiri, S. Y., Iwamoto, N., … and the Japanese RA Patients with RRP Study Group
- Journal Title
  
  Clinical and experimental rheumatology
  
  Volume: 38(6) Pages: 1096-1101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16210
[Journal Article] IL‐15 is a biomarker involved in the development of rapidly progressive interstitial lung disease complicated with polymyositis/dermatomyositis2020
- Author(s)
  Shimizu T.、Koga T.、Furukawa K.、Horai Y.、Fujikawa K.、Okada A.、Okamoto M.、Endo Y.、Tsuji S.、Takatani A.、Umeda M.、Fukui S.、Sumiyoshi R.、Kawashiri S.‐y.、Iwamoto N.、Igawa T.、Ichinose K.、Tamai M.、Sakamoto N.、Nakamura H.、Origuchi T.、Mukae H.、Kuwana M.、Kawakami A.
- Journal Title
  
  Journal of Internal Medicine
  
  Volume: 289 Issue: 2 Pages: 206-220
- DOI
  10.1111/joim.13154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16210, KAKENHI-PROJECT-18K16153, KAKENHI-PROJECT-20K08543, KAKENHI-PROJECT-20K08520
[Journal Article] A Case Report and Literature Review2020
- Author(s)
  Akagi Midori、Iwanaga Nozomi、Torisu Yuichi、Fujita Hisayuki、Kawahara Chieko、Horai Yoshiro、Izumi Yasumori、Kawakami Atsushi
- Journal Title
  
  Int. Heart J.
  
  Volume: 61 Issue: 2 Pages: 404-408
- DOI
  10.1536/ihj.19-446
- NAID
  130007821505
- ISSN
  1349-2365, 1349-3299
- Year and Date
  2020-03-28
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16210
[Journal Article] Clinical analysis of pre-existing diabetes mellitus and dipeptidyl peptidase-4 inhibitors in patients with remitting seronegative symmetrical synovitis and pitting edema syndrome2020
- Author(s)
  Horai Yoshiro、Origuchi Tomoki、Iwanaga Nozomi、Tokumitsu Junichi、Ikeoka Toshiyuki、Kuriya Genpei、Izumi Yasumori、Kawakami Atsushi
- Journal Title
  
  Modern Rheumatology
  
  Volume: 30 Issue: 4 Pages: 703-707
- DOI
  10.1080/14397595.2019.1666463
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16210
[Journal Article] Comparison of complete renal response and mortality in early- and late-onset lupus nephritis: a multicenter retrospective study of a Japanese cohort2020
- Author(s)
  Ichinose Kunihiro、Kitamura Mineaki、Sato Shuntaro、Fujikawa Keita、Horai Yoshiro、Matsuoka Naoki、Tsuboi Masahiko、Nonaka Fumiaki、Shimizu Toshimasa、Sumiyoshi Remi、Koga Tomohiro、Kawashiri Shin-ya、Iwamoto Naoki、Igawa Takashi、Tamai Mami、Nakamura Hideki、Origuchi Tomoki、Nishino Tomoya、Kawakami Atsushi
- Journal Title
  
  Arthritis Research & Therapy
  
  Volume: 22 Issue: 1 Pages: 175-175
- DOI
  10.1186/s13075-020-02271-3
- NAID
  120006988113
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16210, KAKENHI-PROJECT-18K08411
[Journal Article] A case of simultaneously diagnosed microscopic polyangiitis and lung adenocarcinoma2019
- Author(s)
  Kawaguchi Y, Iwanaga N, Michitsuji T, Kawahara C, Horai Y, Mori H, Nagayoshi Y, Izumi Y, Ito M, Kawakami A.
- Journal Title
  
  Acta Med Nagasaki
  
  Volume: 62 Pages: 69-72
- NAID
  130007683977
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16210
[Journal Article] Swollen joints and peripheral arthritis are signs of malignancy in polymyalgia rheumatica2019
- Author(s)
  Michitsuji Tohru、Iwanaga Nozomi、Horai Yoshiro、Tsuji Yoshika、Kawahara Chieko、Izumi Yasumori、Taniguchi Ken、Yoshida Shinichiro、Kawakami Atsushi
- Journal Title
  
  Modern Rheumatology
  
  Volume: 29 Issue: 6 Pages: 1013-1016
- DOI
  10.1080/14397595.2018.1538027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16210
[Journal Article] Activation of Toll‐like receptor 7 signaling in labial salivary glands of primary Sj?gren's syndrome patients2019
- Author(s)
  Shimizu T.、Nakamura H.、Takatani A.、Umeda M.、Horai Y.、Kurushima S.、Michitsuji T.、Nakashima Y.、Kawakami A.
- Journal Title
  
  Clinical & Experimental Immunology
  
  Volume: 196 Issue: 1 Pages: 39-51
- DOI
  10.1111/cei.13242
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16210
[Journal Article] Factors predictive of long-term mortality in lupus nephritis: a multicenter retrospective study of a Japanese cohort2019
- Author(s)
  Ichinose K、Kitamura M、Sato S、Fujikawa K、Horai Y、Matsuoka N、Tsuboi M、Nonaka F、Shimizu T、Fukui S、Umeda M、Koga T、Kawashiri S、Iwamoto N、Tamai M、Nakamura H、Origuchi T、Nishino T、Kawakami A
- Journal Title
  
  Lupus
  
  Volume: 28 Issue: 3 Pages: 295-303
- DOI
  10.1177/0961203319826690
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16210, KAKENHI-PROJECT-17K09977
[Journal Article] Giant Cell Arteritis with Generalized Granuloma Annulare2019
- Author(s)
  Torisu Yuichi、Horai Yoshiro、Michitsuji Tohru、Kawahara Chieko、Mori Takahiro、Iwanaga Nozomi、Izumi Yasumori、Kawakami Atsushi
- Journal Title
  
  Intern. Med.
  
  Volume: 58 Issue: 8 Pages: 1173-1177
- DOI
  10.2169/internalmedicine.1978-18
- NAID
  130007632727
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2019-04-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16210
[Journal Article] Detection of human T lymphotropic virus type-I bZIP factor and tax in the salivary glands of Sjögren's syndrome patients2018
- Author(s)
  11.Nakamura H, Hasegawa H, Sasaki D, Takatani A, Shimizu T, Kurushima S, Horai Y, Nakashima Y, Nakamura T, Fukuoka J, Kawakami A.
- Journal Title
  
  Clin Exp Rheumatol
  
  Volume: 36 Suppl 112 Pages: 51-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16210
[Journal Article] Combined classification system based on ACR/EULAR and ultrasonographic scores for improving the diagnosis of Sjogren's syndrome2018
- Author(s)
  Takagi Y, Nakamura H, Sumi M, Shimizu T, Horai Y, Eida S, Sasaki M, Nakamura T
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Issue: 4 Pages: 1-15
- DOI
  10.1371/journal.pone.0195113
- NAID
  120006987320
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11674, KAKENHI-PROJECT-15K11078, KAKENHI-PROJECT-17K11675, KAKENHI-PROJECT-17K16210
[Journal Article] The efficacy of adjunct tacrolimus treatment in pregnancy outcomes in patients with systemic lupus erythematosus2018
- Author(s)
  Ichinose K、Sato S、Kitajima Y、Horai Y、Fujikawa K、Umeda M、Fukui S、Nishino A、Koga T、Kawashiri S Y、Iwamoto N、Tamai M、Nakamura H、Origuchi T、Yasuhi I、Masuzaki H、Kawakami A
- Journal Title
  
  Lupus
  
  Volume: - Issue: 8 Pages: 1312-1320
- DOI
  10.1177/0961203318770536
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19605, KAKENHI-PROJECT-17K09977, KAKENHI-PROJECT-17K16210
[Journal Article] M1 and M2 Monocytes in Rheumatoid Arthritis: A Contribution of Imbalance of M1/M2 Monocytes to Osteoclastogenesis2018
- Author(s)
  Fukui Shoichi、Iwamoto Naoki、Takatani Ayuko、Igawa Takashi、Shimizu Toshimasa、Umeda Masataka、Nishino Ayako、Horai Yoshiro、Hirai Yasuko、Koga Tomohiro、Kawashiri Shin-ya、Tamai Mami、Ichinose Kunihiro、Nakamura Hideki、Origuchi Tomoki、Masuyama Ritsuko、Kosai Kosuke、Yanagihara Katsunori、Kawakami Atsushi
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 8 Pages: 1958-1958
- DOI
  10.3389/fimmu.2017.01958
- NAID
  120006987316
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09531, KAKENHI-PROJECT-17K19771, KAKENHI-PROJECT-17K16210, KAKENHI-PROJECT-17H01967, KAKENHI-PROJECT-16K19605, KAKENHI-PROJECT-16K19606
[Journal Article] Modulation of Apoptosis by Cytotoxic Mediators and Cell-Survival Molecules in Sj?gren’s Syndrome2018
- Author(s)
  Nakamura Hideki、Horai Yoshiro、Shimizu Toshimasa、Kawakami Atsushi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 19 Issue: 8 Pages: 2369-2369
- DOI
  10.3390/ijms19082369
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16210
[Journal Article] Development of Diffuse Alveolar Hemorrhage during Maintenance Therapy for Systemic Lupus Erythematosus: a Case Report2018
- Author(s)
  Horai Y, Michitsuji T, Chikamatsu G, Moritsuka T, Torisu Y, Kubota Y, Iwanaga N, Iwanaga N, Izumi Y.
- Journal Title
  
  Clin Rheumatol Rel Res
  
  Volume: 30 Pages: 175-82
- NAID
  130007657461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16210
[Journal Article] Serum cytokine profiles and Mac-2 binding protein glycosylation isomer (M2BPGi) level in patients with autoimmune hepatitis2018
- Author(s)
  Migita K, Horai Y, Kozuru H, Koga T, Abiru S, Yamasaki K, et al.
- Journal Title
  
  Medicine
  
  Volume: 97 Issue: 50 Pages: e13450-e13450
- DOI
  10.1097/md.0000000000013450
- NAID
  120007128247
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16210
[Journal Article] Podocyte foot process width is a prediction marker for complete renal response at 6 and 12 months after induction therapy in lupus nephritis.2018
- Author(s)
  Ichinose K, Kitamura M, Sato S, Fujikawa K, Horai Y, Matsuoka N, Tsuboi M, Nonaka F, Shimizu T, Fukui S, Umeda M, Koga T, Kawashiri SY, Iwamoto N, Igawa T, Tamai M, Nakamura H, Origuchi T, Nishino T, Kawakami A.
- Journal Title
  
  Clin Immunol.
  
  Volume: 197 Pages: 161-168
- DOI
  10.1016/j.clim.2018.10.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09977, KAKENHI-PROJECT-18K08411, KAKENHI-PROJECT-17K16210
[Journal Article] Anti-SS-A antibody-negative/anti-SS-B antibody-positive Sjögren's syndrome with increased serum concentration and lymph node infiltration of immunoglobulin G4: a case report2018
- Author(s)
  Horai Y, Izumi Y, Michitsuji T, Iwanaga N, Nakashima Y, Nakamura H, Ito M, Kawakami A.
- Journal Title
  
  Clin Rheumatol Rel Res
  
  Volume: 30 Pages: 276-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16210
[Journal Article] Therapeutic effect of certolizumab pegol in patients with rheumatoid arthritis in daily clinical practice: A single-center, retrospective study2018
- Author(s)
  Horai Y, IwanagaN, Izumi Y, Migita K.
- Journal Title
  
  Clin Rheumatol Rel Res
  
  Volume: 30 Pages: 98-106
- NAID
  130007502007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16210
[Journal Article] Efficacy of infliximab as a switched biologic in rheumatoid arthritis patients in daily clinical practice2018
- Author(s)
  Umeda Masataka、Koga Tomohiro、Ichinose Kunihiro、Takatani Ayuko、Igawa Takashi、Shimizu Toshimasa、Fukui Shoichi、Nishino Ayako、Horai Yoshiro、Hirai Yasuko、Kawashiri Shin-Ya、Iwamoto Naoki、Tamai Mami、Nakamura Hideki、Origuchi Tomoki、Aramaki Toshiyuki　et al.
- Journal Title
  
  Immunological Medicine
  
  Volume: 41 Issue: 4 Pages: 181-186
- DOI
  10.1080/25785826.2018.1542942
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08411, KAKENHI-PROJECT-17K16210
[Journal Article] CD4+ CD52lo T-cell expression contributes to the development of systemic lupus erythematosus.2018
- Author(s)
  Umeda M, Koga T, Ichinose K(corresponding author), Igawa T, Sato T, Takatani A, Shimizu T, Fukui S, Nishino A, Horai Y, Hirai Y, Kawashiri SY, Iwamoto N, Aramaki T, Tamai M, Nakamura H, Yamamoto K, Abiru N, Origuchi T, Ueki Y, Kawakami A.
- Journal Title
  
  Clin Immunol.
  
  Volume: 187 Pages: 50-57
- DOI
  10.1016/j.clim.2017.10.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09977, KAKENHI-PROJECT-17K16210, KAKENHI-PROJECT-16K19604, KAKENHI-PROJECT-16K19605, KAKENHI-PROJECT-16H06276
[Journal Article] Protein-losing gastroenteropathy in a patient with concomitant systemic lupus erythematosus and Sjögren’s syndrome2018
- Author(s)
  Eguchi M, Iwanaga N, Sakai K, Michitsuji T, Tsuji Y, Kawahara C, Kobayashi H, Horai Y, Mori T, Izumi Y, Ito M, Kawakami A.
- Journal Title
  
  Immunological Medicine
  
  Volume: 41 Issue: 1 Pages: 34-38
- DOI
  10.1080/09114300.2018.1451614
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16210
[Journal Article] A case of mixed connective tissue disease positive for proteinase 3 antineutrophil cytoplasmic antibody in a patient with slowly progressive type 1 diabetes mellitus and chronic thyroiditis2017
- Author(s)
  Michitsuji T, Horai Y, Sako A, Asano T, Iwanaga N, Izumi Y, Kawakami A.
- Journal Title
  
  Japanese Journal of Clinical Immunology
  
  Volume: 40 Issue: 6 Pages: 467-470
- DOI
  10.2177/jsci.40.467
- NAID
  130006319725
- ISSN
  0911-4300, 1349-7413
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16210
[Journal Article] Phalangeal Microgeodic Syndrome in a Patient with Systemic Lupus Erythematosus2017
- Author(s)
  Kurushima S, Horai Y, Takatani A, Nishino A, Kawashiri SY, Ichinose K, Nakamura H, Kawakami A
- Journal Title
  
  Intern. Med.
  
  Volume: 56 Issue: 24 Pages: 3385-3387
- DOI
  10.2169/internalmedicine.9195-17
- NAID
  130006250545
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16210
[Journal Article] Coexistence of Takayasu's arteritis and inflammatory colitis detected by fluorodeoxyglucose positron emission tomography2017
- Author(s)
  Horai Y, Kurushima S, Igawa T, Ichinose K, Nakamura H, Kawakami A.
- Journal Title
  
  Japanese Journal of Clinical Immunology
  
  Volume: 40 Issue: 5 Pages: 387-390
- DOI
  10.2177/jsci.40.387
- NAID
  130006251854
- ISSN
  0911-4300, 1349-7413
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16210
[Journal Article] Efficacy and safety at 24 weeks of daily clinical use of tofacitinib in patients with rheumatoid arthritis2017
- Author(s)
  Iwamoto N, Tsuji S, Takatani A, Shimizu T, Fukui S, Umeda M, Nishino A, Horai Y, Koga T, Kawashiri SY, Aramaki T, Ichinose K, Hirai Y, Tamai M, Nakamura H, Terada K, Origuchi T, Eguchi K, Ueki Y, Kawakami A
- Journal Title
  
  PLoS One
  
  Volume: 12 Issue: 5 Pages: 0177057-0177057
- DOI
  10.1371/journal.pone.0177057
- NAID
  120006987500
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16210, KAKENHI-PROJECT-16K19605
[Journal Article] Steroid Treatment of Remitting Seronegative Symmetrical Synovitis with Pitting Edema Syndrome Complicated by Pleural Effusion : A Case Report2017
- Author(s)
  HORAI Y, MATSUO Y, TAKEMOTO S, IWANAGA N, IZUMI Y.
- Journal Title
  
  Fukuoka Igaku Zasshi
  
  Volume: 108 Pages: 217-222
- NAID
  120006413995
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16210
[Journal Article] Anti-citrullinated peptide antibodies are the strongest predictor of clinically relevant radiographic progression in rheumatoid arthritis patients achieving remission or low disease activity: A post hoc analysis of a nationwide cohort in Japan2017
- Author(s)
  Koga T, Okada A, Fukuda T, Hidaka T, Ishii T, Ueki Y, Kodera T, Nakashima M, Takahashi Y, Honda S, Horai Y, et al.
- Journal Title
  
  PLoS One
  
  Volume: 12 Issue: 5 Pages: e0175281-e0175281
- DOI
  10.1371/journal.pone.0175281
- NAID
  120006987476
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16210
[Journal Article] Anti-transcription Intermediary Factor1γ-antibody-positive Dermatomyositis Complicated by Dysphagia2017
- Author(s)
  Kurushima S, Horai Y, Umeda M, Kawakami A
- Journal Title
  
  Intern. Med.
  
  Volume: 56 Issue: 21 Pages: 2965-2966
- DOI
  10.2169/internalmedicine.9149-17
- NAID
  130006191979
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16210
[Journal Article] Baseline MRI bone erosion predicts the subsequent radiographic progression in early rheumatoid arthritis patients who achieved sustained good clinical response.2017
- Author(s)
  Tamai M, Arima K, Nakashima Y, Kita J, Umeda M, Fukui S, Nishino A, Suzuki T, Horai Y, Okada A, Koga T, Kawashiri SY, Iwamoto N, Ichinose K, Yamasaki S, Nakamura H, Origuchi T, Aoyagi K, Uetani M, Eguchi K, Kawakami A
- Journal Title
  
  Mod Rheumatol
  
  Volume: 印刷中 Issue: 6 Pages: 1-6
- DOI
  10.1080/14397595.2017.1294280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461829, KAKENHI-PROJECT-15K09531, KAKENHI-PROJECT-17K16210
[Journal Article] Direct infection of primary salivary gland epithelial cells by HTLV-I that induces the niche of the salivary glands of Sjögren’s syndrome patients.2015
- Author(s)
  Nakamura H, Takahashi Y, Yamamoto-Fukuda T, Horai Y, Nakashima Y, Arima K, Nakamura T, Koji T, Kawakami A.
- Journal Title
  
  Arthritis Rheumatol.
  
  Volume: 67 Issue: 4 Pages: 1096-1106
- DOI
  10.1002/art.39009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591267, KAKENHI-PROJECT-25461477, KAKENHI-PROJECT-25461478, KAKENHI-PROJECT-26650174
[Presentation] リウマチ性多発筋痛症の病態に対する性別と既存糖尿病の関与についての臨床的検討2022
- Author(s)
  寶來吉朗, 大塚瑞奈, 川原知瑛子, 岩永希, 山﨑悠介, 渡部太郎, 安井順一, 最勝寺佑介, 鳥巣裕一, 森隆浩, 森英毅, 和泉泰衛, 川上純
- Organizer
  第63回九州リウマチ学会
- Data Source
  KAKENHI-PROJECT-17K16210
[Presentation] 長崎県のRS3PE症候群患者における既存糖尿病と治療薬についての後ろ向き研究2021
- Author(s)
  寶來吉朗，清水俊匡, 岡田覚丈, 徳満純一, 池岡俊幸, 厨　源平, 岩永希，和泉泰衛，折口智樹, 川上純
- Organizer
  第61回九州リウマチ学会
- Data Source
  KAKENHI-PROJECT-17K16210
[Presentation] シェーグレン症候群小唾液腺における LncRNA NRON及びNFATc1関連分子発現の解析2021
- Author(s)
  寶來吉朗, 中村英樹, 清水俊匡, 西畑伸哉, 岩本直樹, 黒木保, 岡野慎士, 川上純
- Organizer
  第29回日本シェーグレン症候群学会
- Data Source
  KAKENHI-PROJECT-17K16210
[Presentation] LncRNA NRON upregulation associates with clinical manifestations of Sjogren's syndrome by keeping NFATc1 and PIM-1 in the cytoplasm in labial salivary glands2020
- Author(s)
  Yoshiro Horai, Hideki Nakamura, Toshimasa Shimizu, Naoki Iwamoto, Atsushi Kawakami
- Organizer
  第65回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17K16210
[Presentation] RS3PE症候群患者における既存糖尿病と治療薬についての臨床的検討2019
- Author(s)
  寶來吉朗，折口智樹，岩永希，徳満純一，池岡俊幸，厨源平，和泉泰衛，川上純
- Organizer
  第57回九州リウマチ学会
- Data Source
  KAKENHI-PROJECT-17K16210
[Presentation] ステロイド反応性胸水を合併したRS3PE症候群の1例2018
- Author(s)
  松尾友里子, 和泉泰衛, 竹本真之輔, 寶來吉朗, 岩永希
- Organizer
  第320回日本内科学会九州地方会
- Data Source
  KAKENHI-PROJECT-17K16210
[Presentation] 当科におけるセルトリズマブペゴル使用関節リウマチの治療効果に関する後ろ向き研究2018
- Author(s)
  寶來吉朗, 岩永希, 和泉泰衛, 右田清志
- Organizer
  第62回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17K16210
[Presentation] 高IgG4血症及び耳介組織へのIgG4陽性形質細胞浸潤を認めた抗SS-A抗体陰性/抗SS-B抗体陽性シェーグレン症候群の1例2018
- Author(s)
  寶來吉朗, 和泉泰衛, 道辻徹, 岩永希, 中島好一, 中村英樹, 伊東正博, 川上純
- Organizer
  第27回日本シェーグレン症候群学会学術集会
- Data Source
  KAKENHI-PROJECT-17K16210
[Presentation] シェーグレン症候群唾液腺上皮細胞へのHTLV-I直接感染と関連分子発現について2015
- Author(s)
  中村英樹、高橋良子、福田智美、寶來吉朗、中島好一、有馬和彦、小路武彦、川上純
- Organizer
  第59回日本リウマチ学会総会学術集会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-25461477
[Presentation] シェーグレン症候群唾液腺上皮細胞に対するHTLV-I感染のin vitroでの影響について
- Author(s)
  中村英樹、高橋良子、寶來吉朗、福田智美、有馬和彦、中村龍文、小路武彦、川上純
- Organizer
  第42回日本臨床免疫学会
- Place of Presentation
  京王プラザホテル（東京）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25461477
[Presentation] シェーグレン症候群唾液腺上皮細胞に対するHTLV-I感染のin vitroでの影響について
- Author(s)
  中村英樹、高橋良子、寶來吉朗、福田智美、中村龍文、小路武彦、川上純
- Organizer
  第58回日本リウマチ学会
- Place of Presentation
  グランドプリンスホテル新高輪(東京）
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-25461477

1. NAKAMURA Hideki (10437832)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
2. KAWAKAMI ATSUSHI (90325639)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
3. NAKAMURA TATSUFUMI (00198219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. IWAMOTO Naoki

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
5. KAWASHIRI Shinya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 角美佐

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 榮田智

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 高木幸則

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 佐々木美穂

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 中村卓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 一瀬邦弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
12. 玉井慎美

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
13. 古賀智裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 上谷雅孝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HORAI Yoshiro 寶來 吉朗

HORAI YOSHIRO 寶來 吉朗

寳來 吉朗 ホウライ ヨシロウ

Research Projects

Research Products

Co-Researchers

LncRNAと関連分子の包括的解析によるシェーグレン症候群病態解明と治療標的同定Principal Investigator

Principal Investigator

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Review Section

Research Institution

LncRNA in labial salivary glands of Sjogren's syndrome patientsPrincipal Investigator

Principal Investigator

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Research Institution

Elucidation of mechanism for HTLV-I-associated Sjogren's syndrome

Principal Investigator

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Research Institution

[Book] シェーグレン症候群の診断と治療マニュアル(第4章 臨床症状 2.腺外症状 7 原発性シェーグレン症候群の筋・骨格系徴候；筋・関節病変)2018

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[Journal Article] Human leucocyte antigens and Japanese patients with polymyalgia rheumatica: the protective effect of<i>DRB1*09:01</i>2024

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[Journal Article] Takayasu’s arteritis after a prolonged course of hypertrophic osteoarthropathy2023

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[Journal Article] Current Views on Pathophysiology and Potential Therapeutic Targets in Sjoegren’s Syndrome: A Review from the Perspective of Viral Infections, Toll-like Receptors, and Long-Noncoding RNAs2023

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[Journal Article] Comparison of complications during 1-year follow-up between remitting seronegative symmetrical synovitis with pitting edema syndrome and elderly-onset rheumatoid arthritis2022

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[Journal Article] Clinical analysis of gender and pre-existing diabetes mellitus in patients with polymyalgia rheumatica: A retrospective study in a Japanese population2022

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[Journal Article] Clinical Characteristics of Patients With IgG4-Related Disease Complicated by Hypocomplementemia2022

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[Journal Article] Comparison of the quantitative measurement of 18F-FDG PET/CT and histopathological findings in IgG4-related disease.2021

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[Journal Article] Increased Expression of the lncRNA NRON Along With NFATc1/PIM-1 in Labial Salivary Glands of Sj?gren’s Syndrome Patients2021

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[Journal Article] Development of hypocomplementemic urticarial vasculitis during certolizumab pegol treatment for rheumatoid arthritis: A case report2020

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[Journal Article] Rheumatoid arthritis patients with low baseline Health Assessment Questionnaire scores have a risk of functional disability progression: a post hoc analysis of a nationwide longitudinal cohort in Japan2020

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[Journal Article] IL‐15 is a biomarker involved in the development of rapidly progressive interstitial lung disease complicated with polymyositis/dermatomyositis2020

Author(s)

Journal Title

HORAI Yoshiro 寶來吉朗

HORAI YOSHIRO 寶來吉朗

寳來吉朗ホウライヨシロウ

[Book] シェーグレン症候群の診断と治療マニュアル(第4章臨床症状 2.腺外症状 7 原発性シェーグレン症候群の筋・骨格系徴候；筋・関節病変)2018

[Journal Article] Detection of human T lymphotropic virus type-I bZIP factor and tax in the salivary glands of Sjögren's syndrome patients2018