ishibashi tomohiko 石橋知彦

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Ishibashi Tomohiko 石橋知彦

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Researcher Number	30722285
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立循環器病研究センター, 研究所, 上級研究員
Affiliation (based on the past Project Information) *help	2016 – 2023: 国立研究開発法人国立循環器病研究センター, 研究所, 上級研究員 2018: 国立研究開発法人国立循環器病研究センター, 研究所, 研究員 2016: 国立研究開発法人国立循環器病研究センター, 研究所, 研究員 2014 – 2015: 大阪大学, 医学部附属病院, その他 2014 – 2015: 大阪大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related / Hematology Except Principal Investigator Basic Section 53020:Cardiology-related / Basic Section 52050:Embryonic medicine and pediatrics-related / Hematology
Keywords	Principal Investigator 造血幹細胞 / サイトカイン / IL-6 / gp130 / 肺動脈性肺高血圧症 / インターロイキン-6 / CD4 T細胞 / 肺血管リモデリング / CD4陽性細胞 / interleukin-6 … More / 肺高血圧症 / 血管平滑筋 / リンパ球 / 平滑筋細胞 / 血液内科学 / Klf2 / 血管内皮細胞 / KLF2 … More Except Principal Investigator 炎症 / Interleukin-6 / 血管リモデリング / 肺動脈性肺高血圧症 / 炎症性サイトカイン / 肺高血圧症 / フォンタン関連肝臓病 / 慢性心不全 / フォンタン循環 / 腸内細菌叢 / 肝硬変 / 心不全 / 腸内細菌 / フォンタン / 免疫細胞 / 炎症性サイトカイ / Interleukin-21 / 右心不全 / ヘルパーT細胞 / 肺血管リモデリング / interleukin-6 / 血球分化 / MS4A3 / SATB1 / 造血幹細胞 Less

炎症シグナルによる肺動脈性肺高血圧症の発症機構解明に向けた基盤的研究
- Principal Investigator
  
  稲垣薫克
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  National Cardiovascular Center Research Institute
Study of intestinal dysbiosis in patients with Fontan Circulation
- Principal Investigator
  
  大内秀雄
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  National Cardiovascular Center Research Institute
Role of gp130-dependent cytokine signaling in pulmonary hypertensionPrincipal Investigator
- Principal Investigator
  
  Ishibashi Tomohiko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  National Cardiovascular Center Research Institute
Fundamental research for the development of a new strategy for the treatment of severe pulmonary hypertension by IL-6 blockade
- Principal Investigator
  
  Inagaki Tadakatsu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  National Cardiovascular Center Research Institute
The role of hematopoietic lineage cells marked by smooth muscle-targeted Cre mice in cardiovascular diseasesPrincipal Investigator
- Principal Investigator
  
  Ishibashi Tomohiko
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  National Cardiovascular Center Research Institute
The role of transcription factor KLF2 in the regulation of hematopoiesisPrincipal Investigator
- Principal Investigator
  
  Ishibashi Tomohiko
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  National Cardiovascular Center Research Institute
The role of SATB1-MS4A3 in the differentiation of hematopoietic stem cells
- Principal Investigator
  
  SATOH YUSUKE
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kobe Shoin Women's University
ESAM is a novel human hematopoietic stem cell marker associated with a subset of human leukemiasPrincipal Investigator
- Principal Investigator
  
  Ishibashi Tomohiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  National Cardiovascular Center Research Institute
  Osaka University

All 2024 2023 2022 2021 2020 2019 2018 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] IL-6/gp130 signaling in CD4+ T cells drives the pathogenesis of pulmonary hypertension.2024
- Author(s)
  Ishibashi T, Inagaki T, Okazawa M, Yamagishi A, Ohta-Ogo K, Asano R, Masaki T, Kotani Y, Ding X, Chikaishi-Kirino T, Maedera N, Shirai M, Hatakeyama K, Kubota Y, Kishimoto T, Nakaoka Y.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 121 Issue: 16
- DOI
  10.1073/pnas.2315123121
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08144, KAKENHI-PROJECT-21K08070, KAKENHI-PROJECT-23K27605
[Journal Article] Current Immunosuppressive Treatment for Takayasu Arteritis2024
- Author(s)
  Arita Yoh、Ishibashi Tomohiko、Nakaoka Yoshikazu
- Journal Title
  
  Circ J
  
  Volume: 88 Issue: 10 Pages: 1605-1609
- DOI
  10.1253/circj.CJ-23-0780
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2024-09-25
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08070, KAKENHI-PROJECT-23K27605
[Journal Article] Gut dysbiosis is associated with aortic aneurysm formation and progression in Takayasu arteritis2023
- Author(s)
  Manabe Yusuke*, Ishibashi Tomohiko*, et al. (*co-first author)
- Journal Title
  
  Arthritis Research & Therapy
  
  Volume: 25 Issue: 1 Pages: 46-46
- DOI
  10.1186/s13075-023-03031-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08070, KAKENHI-PROJECT-22K16121, KAKENHI-PROJECT-22H04379
[Journal Article] Aryl hydrocarbon receptor is essential for the pathogenesis of pulmonary arterial hypertension2021
- Author(s)
  Masaki T, Okazawa M, Asano R, Inagaki T, Ishibashi T, Yamagishi A, Umeki-Mizushima S, Nishimura M, Manabe Y, Ishibashi-Ueda H, Shirai M, Tsuchimochi H, Pearson JT, Kumanogoh A, Sakata Y, Ogo T, Kishimoto T, Nakaoka Y
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 118 Issue: 11
- DOI
  10.1073/pnas.2023899118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17622, KAKENHI-PROJECT-20K17137, KAKENHI-PROJECT-19K08506
[Journal Article] Autonomous TGFβ signaling induces phenotypic variation in human acute myeloid leukemia2021
- Author(s)
  Yasuhiro Shingai , Takafumi Yokota，et al
- Journal Title
  
  Stem cells
  
  Volume: - Issue: 6 Pages: 723-736
- DOI
  10.1002/stem.3348
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16356, KAKENHI-PROJECT-18K08355, KAKENHI-PROJECT-19K17622, KAKENHI-PROJECT-19K08861, KAKENHI-PROJECT-19K08863, KAKENHI-PROJECT-20K17378, KAKENHI-PROJECT-21K08415
[Journal Article] Ectonucleotidase CD39 is highly expressed on ATLL cells and is responsible for their immunosuppressive function.2020
- Author(s)
  Yasuhiro Nagate, Sachiko Ezoe, Jiro Fujita, Daisuke Okuzakis, Daisuke Motooka, Tomohiko Ishibashi, Michiko Ichii, Akira Tanimura, Masako Kurashige, Eiichi Morii, Takuya Fukushima, Youko Suehiro, Takafumi Yokota, Hirohiko Shibayama, Kenji Oritani, Yuzuru Kanakura
- Journal Title
  
  Leukemia
  
  Volume: － Issue: 1 Pages: 107-118
- DOI
  10.1038/s41375-020-0788-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17622, KAKENHI-PROJECT-19K08861, KAKENHI-PROJECT-18K08355, KAKENHI-PROJECT-19K16585
[Journal Article] Pristane/Hypoxia (PriHx) Mouse as a Novel Model of Pulmonary Hypertension Reflecting Inflammation and Fibrosis2020
- Author(s)
  Mori Hiroyoshi、Ishibashi Tomohiko、Inagaki Tadakatsu、Okazawa Makoto、Masaki Takeshi、Asano Ryotaro、Manabe Yusuke、Ohta-Ogo Keiko、Narazaki Masashi、Ishibashi-Ueda Hatsue、Kumanogoh Atsushi、Nakaoka Yoshikazu
- Journal Title
  
  Circ J
  
  Volume: 84 Issue: 7 Pages: 1163-1172
- DOI
  10.1253/circj.CJ-19-1102
- NAID
  130007864283
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2020-06-25
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08506, KAKENHI-PROJECT-20K17137, KAKENHI-PROJECT-17K10002, KAKENHI-PROJECT-19K17622
[Journal Article] Endothelial Cell-Selective Adhesion Molecule Contributes to the Development of Definitive Hematopoiesis in the Fetal Liver2019
- Author(s)
  Ueda Tomoaki、Yokota Takafumi、Okuzaki Daisuke、Uno Yoshihiro、Mashimo Tomoji、Kubota Yoshiaki、Sudo Takao、Ishibashi Tomohiko、Shingai Yasuhiro、Doi Yukiko、Ozawa Takayuki、Nakai Ritsuko、Tanimura Akira、Ichii Michiko、Ezoe Sachiko、Shibayama Hirohiko、Oritani Kenji、Kanakura Yuzuru
- Journal Title
  
  Stem Cell Reports
  
  Volume: 13 Issue: 6 Pages: 992-1005
- DOI
  10.1016/j.stemcr.2019.11.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08355, KAKENHI-PROJECT-19K08861, KAKENHI-PROJECT-19K08863, KAKENHI-PROJECT-19K17622, KAKENHI-PROJECT-18KK0307, KAKENHI-PROJECT-18H03974, KAKENHI-PROJECT-18K16114
[Journal Article] Identification of MS4A3 as a reliable marker for early myeloid differentiation in human hematopoiesis.2018
- Author(s)
  Ishibashi T, Yokota T, Satoh Y, Ichii M, Sudo T, Doi Y, Ueda T, Nagate Y, Hamanaka Y, Tanimura A, Ezoe S, Shibayama H, Oritani K, Kanakura Y.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 495 Issue: 3 Pages: 2338-2343
- DOI
  10.1016/j.bbrc.2017.12.117
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16201, KAKENHI-PROJECT-16H05339, KAKENHI-PROJECT-15K09475, KAKENHI-PROJECT-17K09903, KAKENHI-PROJECT-16K09871, KAKENHI-PROJECT-16K09874
[Journal Article] Variable SATB1 Levels Regulate Hematopoietic Stem Cell Heterogeneity with Distinct Lineage Fate2018
- Author(s)
  Yukiko Doi, Takafumi Yokota, Yusuke Satoh, Daisuke Okuzaki, Masahiro Tokunaga, Tomohiko Ishibashi, Takao Sudo, Tomoaki Ueda, Yasuhiro Shingai, Michiko Ichii, Akira Tanimura, Sachiko Ezoe, Hirohiko Shibayama, Terumi Kohwi-Shigematsu, Junji Takeda, Kenji Oritani, and Yuzuru Kanakura
- Journal Title
  
  Cell Reports
  
  Volume: 23 Issue: 11 Pages: 3223-3235
- DOI
  10.1016/j.celrep.2018.05.042
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09952, KAKENHI-PROJECT-18K08355, KAKENHI-PROJECT-16H05339, KAKENHI-PROJECT-16K09871, KAKENHI-PROJECT-16K09872, KAKENHI-PROJECT-16K09874, KAKENHI-PROJECT-18K19445, KAKENHI-PROJECT-17K16201
[Journal Article] Endothelial cell-selective adhesion molecule expression in hematopoietic stem/progenitor cells is essential for erythropoiesis recovery after bone marrow injury.2016
- Author(s)
  Sudo T, Yokota T, Okuzaki D, Ueda T, Ichii M, Ishibashi T, Isono T, Habuchi Y, Oritani K, Kanakura Y.
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 4 Pages: e0154189-e0154189
- DOI
  10.1371/journal.pone.0154189
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05339, KAKENHI-PROJECT-15H06373, KAKENHI-PROJECT-26461420, KAKENHI-PROJECT-26461444, KAKENHI-PROJECT-26461446, KAKENHI-PROJECT-15K09475, KAKENHI-PROJECT-16K09872, KAKENHI-PROJECT-16K09874
[Journal Article] ESAM is a novel human hematopoietic stem cell marker associated with a subset of human leukemias.2016
- Author(s)
  Ishibashi T, Yokota T, Tanaka H, Ichii M, Sudo T, Satoh Y, Doi Y, Ueda T, Tanimura A, Hamanaka Y, Ezoe S, Shibayama H, Oritani K, Kanakura Y.
- Journal Title
  
  Experimental Hematology
  
  Volume: 44 Issue: 4 Pages: 269-281
- DOI
  10.1016/j.exphem.2015.12.010
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09475, KAKENHI-PROJECT-26461412, KAKENHI-PROJECT-26461446, KAKENHI-PROJECT-25461418, KAKENHI-PROJECT-25461439, KAKENHI-PROJECT-16H05339, KAKENHI-PROJECT-15H06373, KAKENHI-PROJECT-26461420, KAKENHI-PROJECT-26461444, KAKENHI-PROJECT-15K09461, KAKENHI-PROJECT-16K09862, KAKENHI-PROJECT-16K09872
[Journal Article] Estrogen-inducible sFRP5 inhibits early B-lymphopoiesis in vivo, but not during pregnancy2015
- Author(s)
  Takafumi Yokota, Kenji Oritani, Takao Sudo, Tomohiko Ishibashi1, Yukiko Doi, Yoko Habuchi, Michiko Ichii, Kentaro Fukushima, Daisuke Okuzaki, Kazuma Tomizuka, Kengo Yamawaki, Makoto Kakitani, Akihiko Shimono, Eiichi Morii, Paul W. Kincade, Yuzuru Kanakura
- Journal Title
  
  European Journal of Immunology
  
  Volume: in press Issue: 5 Pages: 1390-1401
- DOI
  10.1002/eji.201444939
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591423, KAKENHI-PROJECT-25461450, KAKENHI-PROJECT-26461412, KAKENHI-PROJECT-26461420, KAKENHI-PROJECT-15H06373, KAKENHI-PROJECT-25461418, KAKENHI-PROJECT-25293220
[Journal Article] The anti-apoptotic gene Anamorsin is essential for both autonomous and extrinsic regulation of murine fetal liver hematopoiesis.2014
- Author(s)
  Tanimura A, Shibayama H, Hamanaka Y, Fujita N, Ishibashi T, Sudo T, Yokota T, Ezoe S, Tanaka H, Matsumura I, Oritani K, Kanakura Y.
- Journal Title
  
  Exp Hematol.
  
  Volume: 42 Issue: 5 Pages: 410-422
- DOI
  10.1016/j.exphem.2014.01.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-25130712, KAKENHI-PROJECT-25293220, KAKENHI-PROJECT-25461416, KAKENHI-PROJECT-25461439, KAKENHI-PROJECT-25461449, KAKENHI-PROJECT-26461401, KAKENHI-PROJECT-26461412
[Presentation] IL-6/gp130 signaling in CD4+ T cells drives the pathogenesis of pulmonary hypertension.2024
- Author(s)
  Tadakatsu Inagaki, Tomohiko Ishibashi, Makoto Okazawa, Ryotaro Asano, Yoshikazu Nakaoka
- Organizer
  第88回日本循環器学会
- Data Source
  KAKENHI-PROJECT-21K08070
[Presentation] IL-6/gp130 signaling in CD4+ T cells drives the pathogenesis of pulmonary hypertension.2024
- Author(s)
  Tadakatsu Inagaki, Tomohiko Ishibashi, Makoto Okazawa, Ryotaro Asano, Yoshikazu Nakaoka
- Organizer
  第88回日本循環器学会
- Data Source
  KAKENHI-PROJECT-22K08144
[Presentation] Interleukin-6欠損による肺高血圧症病態形成の抑制2023
- Author(s)
  稲垣薫克、石橋知彦、山岸亜希子、丁欣、岡澤慎、中岡良和
- Organizer
  第8回日本肺高血圧・肺循環学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08070
[Presentation] CD4陽性細胞のIL-6シグナルを介した肺高血圧症病態形成2023
- Author(s)
  稲垣薫克、石橋知彦、岡澤慎、浅野遼太郎、中岡良和
- Organizer
  第31回日本血管生物医学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08070
[Presentation] CD4陽性細胞のIL-6シグナルを介した肺高血圧症病態形成2023
- Author(s)
  稲垣薫克、石橋知彦、岡澤慎、浅野遼太郎、中岡良和
- Organizer
  第31回日本血管生物医学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08144
[Presentation] Interleukin-6欠損による肺高血圧症病態形成の抑制2023
- Author(s)
  稲垣薫克、石橋知彦、山岸亜希子、丁欣、岡澤慎、中岡良和
- Organizer
  第8回日本肺高血圧・肺循環学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08144
[Presentation] IL-6 signaling in the pathogenesis of pulmonary arterial hypertension2022
- Author(s)
  Tomohiko Ishibashi, Yoshikazu Nakaoka
- Organizer
  CVMW2022
- Data Source
  KAKENHI-PROJECT-21K08070
[Presentation] Anti-interleukin-21 aptamer treatment improves pathology in a rodent models of pulmonary hypertension.2021
- Author(s)
  Tadakatsu Inagaki, Ryotaro Asano, Marie Mitsui, Tomohiko Ishibashi, Makoto Okazawa, Takeshi Ogo, Yoshikazu Nakaoka
- Organizer
  The 5th JCS Council Forum on Basic Cardio Vascular Research
- Data Source
  KAKENHI-PROJECT-19K08506
[Presentation] 肺高血圧症における IL-6 の重要性:遺伝子改変ラットを用いた検討2021
- Author(s)
  稲垣薫克, 石橋知彦, 岡澤慎, 正木豪, 真鍋侑資, 浅野遼太郎, 中岡良和
- Organizer
  第29回日本血管生物医学会学術集会 (CVMW2021)
- Data Source
  KAKENHI-PROJECT-21K08070
[Presentation] 芳香族炭化水素受容体を介した肺動脈性肺高血圧症の病態形成メカニズム2021
- Author(s)
  岡澤慎, 正木豪, 浅野遼太郎, 稲垣薫克, 石橋知彦, 山岸亜紀子, 真鍋侑資, 大郷剛, 中岡良和
- Organizer
  第29回日本血管生物医学会学術集会 (CVMW2021)
- Data Source
  KAKENHI-PROJECT-21K08070
[Presentation] The role of gp130-mediated IL-6 signaling in the CD4+ lymphocytes for the pathogenesis of pulmonary arterial hypertension2021
- Author(s)
  Ishibashi T, Masaki T, Inagaki T, Chikaishi-Kirino T, Okazawa M, Nakaoka Y
- Organizer
  第5回日本循環器学会基礎研究フォーラム (BCVR)
- Data Source
  KAKENHI-PROJECT-21K08070
[Presentation] Anti-interleukin-21 aptamer treatment improves pathology in a rodent models of pulmonary hypertension2021
- Author(s)
  Inagaki T, Asano R, Mitsui M, Ishibashi T, Okazawa M, Ogo T, Nakaoka Y
- Organizer
  第5回日本循環器学会基礎研究フォーラム (BCVR)
- Data Source
  KAKENHI-PROJECT-21K08070
[Presentation] 肺高血圧症におけるIL-6の重要性：遺伝子改変ラットを用いた検討2021
- Author(s)
  稲垣薫克、石橋知彦、岡澤慎、正木豪、真鍋侑資、浅野遼太郎、大郷剛、中岡良和
- Organizer
  第29回日本血管生物医学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08506
[Presentation] Interleukin-21阻害による肺動脈性肺高血圧症の新規治療法開発2020
- Author(s)
  稲垣薫克,浅野遼太郎,石橋知彦,岡澤慎,正木豪,三井麻利江,青木一晃,大郷剛,中岡良和
- Organizer
  第5回日本肺高血圧・肺循環学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08506
[Presentation] gp130 signaling in CD4 cells is important for the pathogenesis of pulmonary arterial hypertension2020
- Author(s)
  Ishibashi T, Masaki T, Inagaki T, Okazawa M, Nakaoka Y
- Organizer
  IVBM 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17622
[Presentation] IL-6 signaling in the CD4-positive T cells is important for the pathogenesis of PAH2020
- Author(s)
  Ishibashi T, Masaki T, Inagaki T, Asano R, Okazawa M, Nakaoka Y
- Organizer
  第4回日本循環器学会基礎研究フォーラム (BCVR)
- Data Source
  KAKENHI-PROJECT-19K17622
[Presentation] Critical Roles of Interleukin-21 Signaling in the Pathogenesis of Pulmonary Arterial Hypertension2020
- Author(s)
  Tadakatsu Inagaki, Tomohiko Ishibashi, Makoto Okazawa, Takeshi Masaki, Marie Mitsui, Kazuteru Aoki, Ryotaro Asano, Takeshi Ogo, Yoshikazu Nakaoka
- Organizer
  The 21st International Vascular Biology Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08506
[Presentation] Critical Roles of Interleukin-21 Signaling in the Pathogenesis of Pulmonary Arterial Hypertension2020
- Author(s)
  Inagaki T, Ishibashi T, Okazawa M, Masaki T, Mitsui M, Aoki K, Asano R, Ogo T, Nakaoka Y
- Organizer
  IVBM 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17622
[Presentation] gp130 Signaling in CD4 Cells Is Important for the Pathogenesis of Pulmonary Arterial Hypertension2020
- Author(s)
  Tomohiko Ishibashi, Takeshi Masaki, Tadakatsu Inagaki, Makoto Okazawa, Yoshikazu Nakaoka
- Organizer
  The 21st International Vascular Biology Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08506
[Presentation] 肺高血圧症における炎症性サイトカインの意義2020
- Author(s)
  石橋知彦
- Organizer
  第6回血管生物医学会若手研究会
- Data Source
  KAKENHI-PROJECT-19K17622
[Presentation] Interleukin-21阻害による肺動脈性肺高血圧症の新規治療法開発2020
- Author(s)
  稲垣薫克, 浅野遼太郎, 石橋知彦, 岡澤慎, 正木豪, 三井麻利江, 青木一晃, 大郷剛, 中岡良和
- Organizer
  第5回日本肺高血圧・肺循環学会学術集会
- Data Source
  KAKENHI-PROJECT-19K17622
[Presentation] 肺動脈性肺高血圧症の病態形成におけるInterleukin-21の役割の解明と治療法開発2019
- Author(s)
  稲垣薫克, 浅野遼太郎, 三井麻利江, 青木一晃, 石橋知彦, 岡澤慎, 大郷剛, 中岡良和
- Organizer
  第27回日本血管生物医学会学術集会
- Data Source
  KAKENHI-PROJECT-19K17622
[Presentation] CD4陽性細胞におけるgp130シグナルの肺高血圧症病態形成における役割2019
- Author(s)
  石橋知彦, 正木豪, 稲垣薫克, 森啓悦, 浅野遼太郎, 岡澤慎, 中岡良和
- Organizer
  第27回日本血管生物医学会学術集会
- Data Source
  KAKENHI-PROJECT-19K17622
[Presentation] CD4陽性細胞におけるgp130シグナルは肺高血圧症の病態形成に重要である2019
- Author(s)
  石橋知彦、正木豪、稲垣薫克、森啓悦、浅野遼太郎、岡澤慎、中岡良和
- Organizer
  第27回日本血管生物医学会
- Data Source
  KAKENHI-PROJECT-19K08506
[Presentation] TrkB has a protective role for right ventricular dysfunction under chronic hypoxia-induced PH2019
- Author(s)
  Okazawa M, Inagaki T, Ishibashi T, Masaki T, Mori H, Asano R, Takei K, Nakaoka Y
- Organizer
  第3回日本循環器学会基礎研究フォーラム
- Data Source
  KAKENHI-PROJECT-19K17622
[Presentation] CD4陽性細胞のIL-6シグナルは肺高血圧症の病態形成に重要である2019
- Author(s)
  石橋知彦, 正木豪, 稲垣薫克, 森啓悦, 浅野遼太郎, 岡澤慎, 中岡良和
- Organizer
  第4回日本肺高血圧・肺循環学会
- Data Source
  KAKENHI-PROJECT-19K17622
[Presentation] Critical roles of interleukin-21 signaling in the pathogenesis of pulmonary arterial hypertension2019
- Author(s)
  Inagaki T, Mitsui M, Asano R, Ogo T, Aoki K, Masaki T, Ishibashi T, Okazawa M, Nakaoka Y
- Organizer
  第3回日本循環器学会基礎研究フォーラム
- Data Source
  KAKENHI-PROJECT-19K17622
[Presentation] A novel mouse model of connective tissue disease-associated pulmonary arterial hypertension accompanied by infiltration of inflammatory cells2018
- Author(s)
  Mori H, Inagaki T, Ishibashi T, Okazawa M, Masaki T, Asano R, Kumanogoh A, Nakaoka Y
- Organizer
  第26回日本血管生物医学会学術集会 (CVMW2018)
- Data Source
  KAKENHI-PROJECT-17K16201
[Presentation] 平滑筋細胞特異的Creマウスの血液細胞におけるCre発現の解析2018
- Author(s)
  石橋知彦, 稲垣薫克, 森啓悦, 正木豪, 浅野遼太郎, 岡澤慎, 中岡良和
- Organizer
  第26回日本血管生物医学会学術集会 (CVMW2018)
- Data Source
  KAKENHI-PROJECT-17K16201
[Presentation] Cre expression in hematopoietic cells of smooth muscle cell-targeted Cre recombination mice2018
- Author(s)
  Ishibashi T, Inagaki T, Mori H, Masaki T, Asano R, Okazawa M, Nakaoka Y
- Organizer
  第2回日本循環器学会基礎研究フォーラム
- Data Source
  KAKENHI-PROJECT-17K16201
[Presentation] プリスタンを用いた新しい膠原病性肺高血圧症モデル作製の試み2018
- Author(s)
  森啓悦, 稲垣薫克, 石橋知彦, 岡澤慎, 正木豪, 中岡良和
- Organizer
  第3回日本肺高血圧・肺循環学会学術集会
- Data Source
  KAKENHI-PROJECT-17K16201
[Presentation] Pristane might be useful for creating a novel model of CTD-PAH in mice2018
- Author(s)
  Mori H, Inagaki T, Ishibashi T, Okazawa M, Masaki T, Asano R, Nakaoka Y
- Organizer
  第2回日本循環器学会基礎研究フォーラム
- Data Source
  KAKENHI-PROJECT-17K16201
[Presentation] A novel mouse model of PAH reflecting inflammation and fibrosis2018
- Author(s)
  Mori H, Inagaki T, Ishibashi T, Okazawa M, Masaki T, Asano R, Nakaoka Y
- Organizer
  The 16th Korea-Japan Joint Symposium on Vasucular Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16201
[Presentation] TrkB might have a role for right vascular homeostasis under chronic hypoxia-induced pulmonary hypertension in mice2018
- Author(s)
  Okazawa M, Inagaki T, Ishibashi T, Masaki T, Mori H, Asano R, Nakaoka Y
- Organizer
  第26回日本血管生物医学会学術集会 (CVMW2018)
- Data Source
  KAKENHI-PROJECT-17K16201
[Presentation] Cre recombination in hematopoietic cells of smooth muscle cell-targeted Cre recombination mice2018
- Author(s)
  Ishibashi T, Inagaki T, Mori H, Masaki T, Okazawa M, Nakaoka Y
- Organizer
  International Vascular Biology Meeting (IVBM) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16201
[Presentation] TrkB might have a role for right ventricular homeostasis under chronic hypoxia-induced pulmonary hypertension2018
- Author(s)
  Okazawa M, Inagaki T, Ishibashi T, Masaki T, Mori H, Asano R, Nakaoka Y
- Organizer
  第2回日本循環器学会基礎研究フォーラム
- Data Source
  KAKENHI-PROJECT-17K16201
[Presentation] A novel mouse model of PAH reflecting inflammation and fibrosis2018
- Author(s)
  森啓悦, 稲垣薫克, 石橋知彦, 岡澤慎, 正木豪, 浅野遼太郎, 熊ノ郷淳, 中岡良和
- Organizer
  第23回日本血管病理研究会
- Data Source
  KAKENHI-PROJECT-17K16201
[Presentation] Cre-mediated recombination in hematopoietic lineage cells of smooth muscle cell-specific targeted Cre mice2018
- Author(s)
  Ishibashi T, Inagaki T, Mori H, Masaki T, Asano R, Okazawa M, Nakaoka Y
- Organizer
  The 16th Korea-Japan Joint Symposium on Vasucular Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16201
[Presentation] Endothelial antigen ESAM is a human HSC marker associated with a subset of human leukemias2016
- Author(s)
  Tomohiko Ishibashi, Takafumi Yokota, Hirokazu Tanaka, Michiko Ichii, Takao Sudo, Yusuke Satoh, Yukiko Doi, Tomoaki Ueda, Akira Tanimura, Yuri Hamanaka, Sachiko Ezoe, Hirohiko Shibayama, Kenji Oritani, Yuzuru Kanakura
- Organizer
  第14回幹細胞シンポジウム
- Place of Presentation
  兵庫県立淡路夢舞台国際会議場
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PROJECT-26461446
[Presentation] SATB1 expression marks lymphoid-lineage-biased hematopoietic stem cells in mouse bone marrow2016
- Author(s)
  横田貴史, 石橋知彦, 佐藤友亮, 一井倫子, 谷村朗, 江副幸子, 柴山浩彦, 織谷健司, 金倉譲
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26461412
[Presentation] ESAM is a human HSC marker associated with a subset of human leukemias2016
- Author(s)
  Tomohiko Ishibashi, Takafumi Yokota, Hirokazu Tanaka, Michiko Ichii, Takao Sudo, Yusuke Satoh, Yukiko Doi, Tomoaki Ueda, Yasuhiro Shingai, Akira Tanimura, Yuri Hamanaka, Sachiko Ezoe, Hirohiko Shibayama, Kenji Oritani, Yuzuru Kanakura
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26461446
[Presentation] Endothelial antigen ESAM is a human hematopoietic stem cell marker associated with a subset of human leukemias2016
- Author(s)
  Tomohiko Ishibashi, Takafumi Yokota, Hirokazu Tanaka, Michiko Ichii, Yoshikazu Nakaoka, Yuzuru Kanakura
- Organizer
  第24回日本血管生物医学会学術集会
- Place of Presentation
  長崎ブリックホール
- Year and Date
  2016-12-09
- Data Source
  KAKENHI-PROJECT-26461446
[Presentation] ESAM Is a Novel Human Hematopoietic Stem Cell Marker Associated with a Subset of Human Leukemias2015
- Author(s)
  Ishibashi T, Yokota T, Tanaka H, Ichii M,　Sudo T, Satoh Y, Doi Y, Tanimura A, Hamanaka Y, Ezoe S, Shibayama H, Oritani K, Kanakura Y.
- Organizer
  57th ASH Annual Meeting and Exposition.
- Place of Presentation
  Orlando, FL
- Year and Date
  2015-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461412
[Presentation] Endothelial cell-selective adhesion molecule is a novel human hematopoietic stem cell marker associated with a subset of human leukemias.2015
- Author(s)
  Tomohiko Ishibashi, Takafumi Yokota, Hirokazu Tanaka, Michiko Ichii, Takao Sudo, Yusuke Satoh, Yukiko Doi, Akira Tanimura, Yuri Hamanaka, Sachiko Ezoe, Hirohiko Shibayama, Kenji Oritani, Yuzuru Kanakura
- Organizer
  International Society for Experimental Hematology 44th Annual Meeting
- Place of Presentation
  International Conference Center, Kyoto, Japan
- Year and Date
  2015-09-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461446
[Presentation] ESAM is a novel human hematopoietic stem cell marker associated with a subset of human leukemias.2015
- Author(s)
  Tomohiko Ishibashi, Takafumi Yokota, Hirokazu Tanaka, Michiko Ichii, Takao Sudo, Yusuke Satoh, Yukiko Doi, Akira Tanimura, Yuri Hamanaka, Sachiko Ezoe, Hirohiko Shibayama, Kenji Oritani, Yuzuru Kanakura
- Organizer
  57th American Society of Hematology Annual Meeting and Exposition
- Place of Presentation
  Orange County Convention Center, Orlando, FL, USA
- Year and Date
  2015-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461446
[Presentation] SATB1 Expression Marks Lymphoid-Lineage-Biased Hematopoietic Stem Cells in Mouse Bone Marrow.2015
- Author(s)
  Doi Y, Yokota T, Ishibashi T, Satoh Y, Ichii M, Tanimura A, Ezoe S, Shibayama H, Oritani K, Kanakura Y.
- Organizer
  57th ASH Annual Meeting and Exposition.
- Place of Presentation
  Orlando, FL
- Year and Date
  2015-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461412
[Presentation] 血管内皮抗原ESAMは幹細胞ソースに関わらずヒト造血幹細胞のマーカーとなる2014
- Author(s)
  石橋知彦, 横田貴史, 一井倫子, 数藤孝雄, 佐藤友亮, 土居由貴子, 藤田奈津子, 長手泰宏, 濱中有理, 松井敬子, 谷村朗, 齋藤則充, 江副幸子, 柴山浩彦, 織谷健司, 金倉譲
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2014-10-31
- Data Source
  KAKENHI-PROJECT-26461446
[Presentation] MS4A3-Marks-Early-Myeloid-Differen>a>on-in-Human-Hematopoiesis.
- Author(s)
  Ishibashi T, Yokota T, Satoh Y, Sudo T, Doi Y, Fujita N, Nagate Y, Hamanaka Y, Matsui K, Tanimura A, Ichii M, Saitoh N, Ezoe S, Shibayama H, Oritani K, Kanakura Y.
- Organizer
  56th ASH Annual Meeting and Exposition.
- Place of Presentation
  San Francisco, CA
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-26461412

1. Inagaki Tadakatsu (20638366)

# of Collaborated Projects: 3 results

# of Collaborated Products: 17 results
2. 横田貴史 (60403200)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
3. 織谷健司 (70324762)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
4. SATOH YUSUKE (20506307)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. TANAKA HIROKAZU (40360846)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 金倉譲 (20177489)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
7. 中岡良和 (90393214)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
8. 大内秀雄 (00517807)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 浅野遼太郎 (60827004)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Tokudome Takeshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 土居由貴子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. 上田智朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 新開泰宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. 小澤孝幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 松村到

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ishibashi tomohiko 石橋 知彦

Ishibashi Tomohiko 石橋 知彦

Research Projects

Research Products

Co-Researchers

炎症シグナルによる肺動脈性肺高血圧症の発症機構解明に向けた基盤的研究

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Study of intestinal dysbiosis in patients with Fontan Circulation

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Role of gp130-dependent cytokine signaling in pulmonary hypertensionPrincipal Investigator

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Fundamental research for the development of a new strategy for the treatment of severe pulmonary hypertension by IL-6 blockade

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The role of hematopoietic lineage cells marked by smooth muscle-targeted Cre mice in cardiovascular diseasesPrincipal Investigator

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The role of transcription factor KLF2 in the regulation of hematopoiesisPrincipal Investigator

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The role of SATB1-MS4A3 in the differentiation of hematopoietic stem cells

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ESAM is a novel human hematopoietic stem cell marker associated with a subset of human leukemiasPrincipal Investigator

Principal Investigator

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[Journal Article] IL-6/gp130 signaling in CD4+ T cells drives the pathogenesis of pulmonary hypertension.2024

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[Journal Article] Current Immunosuppressive Treatment for Takayasu Arteritis2024

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[Journal Article] Gut dysbiosis is associated with aortic aneurysm formation and progression in Takayasu arteritis2023

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[Journal Article] Aryl hydrocarbon receptor is essential for the pathogenesis of pulmonary arterial hypertension2021

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[Journal Article] Autonomous TGFβ signaling induces phenotypic variation in human acute myeloid leukemia2021

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ishibashi tomohiko 石橋知彦

Ishibashi Tomohiko 石橋知彦