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Maruyama Junichi  丸山 順一

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MARUYAMA Junichi  丸山 順一

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Researcher Number 30723639
Other IDs
Affiliation (Current) 2025: 国立研究開発法人理化学研究所, 生命医科学研究センター, 研究員
Affiliation (based on the past Project Information) *help 2025: 国立研究開発法人理化学研究所, 生命医科学研究センター, 研究員
2018 – 2020: 東京医科歯科大学, 大学院医歯学総合研究科, 助教
2016: 東京医科歯科大学, 大学院医歯学総合研究科, 助教
2014 – 2015: 東京医科歯科大学, 医歯(薬)学総合研究科, 助教
Review Section/Research Field
Principal Investigator
Basic Section 47040:Pharmacology-related / Basic Section 49010:Pathological biochemistry-related / General medical chemistry
Except Principal Investigator
General medical chemistry
Keywords
Principal Investigator
DNA損傷修復 / DNA修復 / 肺がん / NF-κB / DCLK1 / 特発性肺線維症 / 癌転移 / 肺癌 / 肺線維症
Except Principal Investigator
腫瘍抑制 … More / シグナル伝達 / 翻訳後修飾 / RASSF / フェイルセーフ / ケミカルバイオロジー / 線維症 / 筋委縮 / がん Less
  • Research Projects

    (5 results)
  • Research Products

    (12 results)
  • Co-Researchers

    (3 People)
  •  トランスオミクス解析による双極性障害治療薬リチウムの作用機序全容解明Principal Investigator

    • Principal Investigator
      丸山 順一
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47040:Pharmacology-related
    • Research Institution
      Institute of Physical and Chemical Research
  •  Functional analysis of DCLK1 in pulmonary cancer associated with IPFPrincipal Investigator

    • Principal Investigator
      MARUYAMA Junichi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 49010:Pathological biochemistry-related
    • Research Institution
      Tokyo Medical and Dental University
  •  Analysis of the molecular pathology of frequently-accompanied pulmonary cancer in fibrotic lungPrincipal Investigator

    • Principal Investigator
      Maruyama Junichi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Tokyo Medical and Dental University
  •  Study on the tumor suppressor Hippo pathway and RASSF proteins

    • Principal Investigator
      Hata Yutaka
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Tokyo Medical and Dental University
  •  Analysis of tumor suppressors RASSF3 and RASSF6

    • Principal Investigator
      Iwasa Hiroaki
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Tokyo Medical and Dental University

All 2021 2019 2018 2017 2016 2015 2014

All Journal Article Presentation

  • [Journal Article] Doublecortin-like kinase 1 expression is induced by alternative NF-κB signaling in human lung cancer cells2021

    • Author(s)
      Yuxiong Lu, Junichi Maruyama, Haruhiko Sugimura and Yutaka Hata
    • Journal Title

      Journal of Medical and Dental Sciences

      Volume: 68 Issue: 0 Pages: 39-48

    • DOI

      10.11480/jmds.680005

    • NAID

      130007995188

    • ISSN
      1342-8810, 2185-9132
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K15059
  • [Journal Article] Doublecortin-like kinase 1 compromises DNA repair and induces chromosomal instability2018

    • Author(s)
      Lu Yuxiong、Maruyama Junichi、Kuwata Keiko、Fukuda Hiroyuki、Iwasa Hiroaki、Arimoto-Matsuzaki Kyoko、Sugimura Haruhiko、Hata Yutaka
    • Journal Title

      Biochemistry and Biophysics Reports

      Volume: 16 Pages: 130-137

    • DOI

      10.1016/j.bbrep.2018.10.014

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08624, KAKENHI-PROJECT-18K15059, KAKENHI-PROJECT-16K19029
  • [Journal Article] Domain analysis of Ras-association domain family member 6 upon interaction with MDM2.2017

    • Author(s)
      Sarkar A, Iwasa H, Hossain S, Xu X, Sawada T, Shimizu T, Maruyama J, Arimoto-Matsuzaki K, Hata Y.
    • Journal Title

      FEBS Letters

      Volume: 591 Issue: 2 Pages: 260-272

    • DOI

      10.1002/1873-3468.12551

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293061, KAKENHI-PROJECT-26460359, KAKENHI-PROJECT-26860185, KAKENHI-PROJECT-16K19029
  • [Journal Article] Validation of the chemical compound library screening for TAZ inhibitors by use of green fluorescence protein-fused TAZ.2016

    • Author(s)
      Nagashima S, Maruyama J, Kawano S, Iwasa H, Nakagawa K, Ishigami-Yuasa M, Kagechika H, Nishina H, Hata Y.
    • Journal Title

      Cancer Sci.

      Volume: - Issue: 6 Pages: 791-802

    • DOI

      10.1111/cas.12936

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460359, KAKENHI-PLANNED-26114005, KAKENHI-PROJECT-26293061, KAKENHI-PROJECT-26293012, KAKENHI-PROJECT-26860185
  • [Journal Article] Osmotic stress induces the phosphorylation of WNK4 Ser575 via the p38MAPK-MK pathway.2016

    • Author(s)
      Maruyama J, Kobayashi Y, Umeda T, Vandewalle A, Takeda K, Ichijo H, Naguro I.
    • Journal Title

      Sci. Rep.

      Volume: 6 Issue: 1 Pages: 18710-18710

    • DOI

      10.1038/srep18710

    • NAID

      120006987229

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26860185, KAKENHI-PROJECT-25221302, KAKENHI-PROJECT-15H04643, KAKENHI-PROJECT-26293016, KAKENHI-PLANNED-26114009
  • [Journal Article] A cell-based screening for TAZ activators identifies ethacridine, a widely used antiseptic and abortifacient, as a compound that promotes dephosphorylation of TAZ and inhibits adipogenesis in C3H10T1/2 cells.2015

    • Author(s)
      Kawano S, Maruyama J, Nagashima S, Inami K, Qiu W, Iwasa H, Nakagawa K, Ishigami-Yuasa M, Kagechika H, Nishina H, Hata Y.
    • Journal Title

      J. Biochem.

      Volume: 158 Issue: 5 Pages: 413-423

    • DOI

      10.1093/jb/mvv051

    • NAID

      40020646985

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460359, KAKENHI-PROJECT-26860185, KAKENHI-PLANNED-26114005, KAKENHI-PROJECT-26293061
  • [Journal Article] A new cell-based assay to evaluate myogenesis in mouse myoblast C2C12 cells2015

    • Author(s)
      Kodaka, M.; Yang, Z.; Nakagawa, K.; Maruyama, J.; Xu, X.; Sarkar, A.; Ichimura, A.; Nasu, Y.; Ozawa, T.; Iwasa, H.; Ishigami-Yuasa, M.; Ito, S.; Kagechika, H.; Hata, Y.
    • Journal Title

      Exp. Cell. Res.

      Volume: 336 Issue: 2 Pages: 171-181

    • DOI

      10.1016/j.yexcr.2015.06.015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26670052, KAKENHI-PROJECT-26860185, KAKENHI-PROJECT-26293061, KAKENHI-PROJECT-26220805
  • [Journal Article] Screening with a Novel Cell-Based Assay for TAZ Activators Identifies a Compound That Enhances Myogenesis in C2C12 Cells and Facilitates Muscle Repair in a Muscle Injury Model.2014

    • Author(s)
      Yang, Z. Y.; Nakagawa, K.; Sarkar, A.; Maruyama, J.; Iwasa, H.; Bao, Y. J.; Ishigami-Yuasa, M.; Ito, S.; Kagechika, H.; Hata, S.; Nishina, H.; Abe, S.; Kitagawa, M.; Hata, Y.
    • Journal Title

      Mol. Cell. Biol.

      Volume: 34 Issue: 9 Pages: 1607-1621

    • DOI

      10.1128/mcb.01346-13

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22136013, KAKENHI-PROJECT-23790325, KAKENHI-PLANNED-26114005, KAKENHI-PROJECT-26293012, KAKENHI-PROJECT-26293061, KAKENHI-PROJECT-26860185
  • [Presentation] Doublecortin-like kinase 1 compromises DNA repair and induces chromosomal instability.2019

    • Author(s)
      Junichi Maruyama, Haruhiko Sugimura and Yutaka Hata
    • Organizer
      第78回日本癌学会学術総会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15059
  • [Presentation] 新規に同定したYAP1活性化化合物は多発性骨髄腫細胞においてYAP1-p73経路依存的な細胞死を誘導する2016

    • Author(s)
      丸山 順一、江 欣亮、岩佐 宏晃、湯浅(石上) 磨里、影近 弘之、仁科 博史、畑 裕
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜、神奈川県横浜市
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-26860185
  • [Presentation] 新規に同定したYAP1活性化化合物は多発性骨髄腫に置いてYAP1-p73経路依存的な細胞死を誘導する2016

    • Author(s)
      丸山順一、江欣亮、岩佐宏晃、湯浅―石上磨里、影近弘之、仁科博史、畑裕
    • Organizer
      日本分子生物学会
    • Place of Presentation
      横浜パシフィコ
    • Data Source
      KAKENHI-PROJECT-26293061
  • [Presentation] 細胞内局在を指標とする探索系による転写共役因子(TAZ)抑制剤探索の有効性の検証2016

    • Author(s)
      長島俊太、丸山順一、湯浅―石上磨里、影近弘之、仁科博史、畑裕
    • Organizer
      日本分子生物学会
    • Place of Presentation
      横浜パシフィコ
    • Data Source
      KAKENHI-PROJECT-26293061
  • 1.  Iwasa Hiroaki (70582188)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 2.  Hata Yutaka (80313237)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 3.  影近 弘之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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