Tachibana Shunsuke 立花俊祐

Researcher Number	30737309
Other IDs	https://orcid.org/0000-0001-7452-4358
Affiliation (Current)	2025: 札幌医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2020 – 2025: 札幌医科大学, 医学部, 助教 2015 – 2019: 札幌医科大学, 医学部, 研究員
Review Section/Research Field	Principal Investigator Basic Section 55050:Anesthesiology-related / Anesthesiology Except Principal Investigator Basic Section 55050:Anesthesiology-related
Keywords	Principal Investigator 麻酔 / セボフルラン / 術後認知機能低下 / トランスクリプトーム解析 / 術後認知機能障害 / マイオカイン / 術後せん妄 / 周術期侵襲 / 脳機能 / コグニティブフレイル … More / 腸内細菌叢 / フレイル / 神経麻酔 / 周術期の腸脳相関 / 神経炎症 / 腸脳相関 / 手術侵襲 / 脳内炎症 / 麻酔侵襲 / dysbiosis / 腸内フローラ / 術後認知機能 / 海馬 / 麻酔手術ストレス / デクスメデトミジン / 手術ストレス … More Except Principal Investigator 術後せん妄 / 腸内細菌叢 / フレイル / 難消化性オリゴ糖 / 周術期神経炎症 / 抗炎症性物質 / 制御性T細胞 / 神経炎症 / プロバイオティクス / 手術侵襲 / 周術期 / 手術ストレス / 急性せん妄 / 行動変化 / せん妄 / 神経麻酔 Less

A novel strategy for postoperative delirium control focusing on Irisin administration -protection the brain frailtyPrincipal Investigator
- Principal Investigator
  
  立花俊祐
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Sapporo Medical University
SIRT6 activation can prevent for exacerbating perioperative frailty : A Novel Strategy
- Principal Investigator
  
  田中聡一
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Sapporo Medical University
Establishment of a strategy to prevent postoperative delirium with the stability of the intestinal microbiota
- Principal Investigator
  
  西原教晃
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Sapporo Medical University
How to reduce anesthesia and surgical invasions in the frail brain - Strategies via gut microbiota regulationPrincipal Investigator
- Principal Investigator
  
  立花俊祐
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Sapporo Medical University
Prevention strategies for perioperative neuroinflammation related diseases with a focus on stabilization of intestinal microbiota
- Principal Investigator
  
  Yamakage Michiaki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Sapporo Medical University
Elucidation of the link between the environmental change in the intestinal flora and cognitive decline due to anesthetic surgeryPrincipal Investigator
- Principal Investigator
  
  Tachibana Shunsuke
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Sapporo Medical University
Elucidation of the mechanism of postoperative cognitive dysfunction through epigeneticsPrincipal Investigator
- Principal Investigator
  
  Tachibana Shunsuke
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Anesthesiology
- Research Institution
  Sapporo Medical University

All 2019 2018 2016 2015

All Journal Article Presentation

[Journal Article] 麻酔科医として術後認知機能障害を俯瞰する2018
- Author(s)
  立花俊祐
- Journal Title
  
  臨床麻酔
  
  Volume: 7 Pages: 1003-9
- Data Source
  KAKENHI-PROJECT-15K20051
[Presentation] デクスメデトミジンは、高齢マウスにおいて手術侵襲由来のMapt発現増大を抑制し、術後の認知機能低下を減弱する。2019
- Author(s)
  立花俊祐
- Organizer
  第23回日本神経集中治療学会
- Data Source
  KAKENHI-PROJECT-15K20051
[Presentation] Dexmedetomidine attenuates up-regulation of the Rtn4rl2 gene and restores down-regulation of the Syt1 gene induced by sevoflurane/surgery stress in the hippocampus of elderly mice2018
- Author(s)
  立花俊祐
- Organizer
  The European anaesthesiology congress, Euroanaesthesia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20051
[Presentation] Dexmedetomidine attenuates up-regulation of the Rtn4rl2 gene and restores down-regulation of the Syt1 gene induced by sevoflurane/surgery stress in the hippocampus of elderly mice2018
- Author(s)
  立花俊祐、山蔭道明
- Organizer
  Euroanaesthesia 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20051
[Presentation] トランスクリプトーム解析を用いた術後認知機能障害の機序解明2016
- Author(s)
  立花俊祐、早瀬知、山蔭道明
- Organizer
  日本麻酔科学会第63回学術集会JAシンポジウム：Neuroscience up to date:postoperative cognitive dysfunction
- Place of Presentation
  福岡
- Year and Date
  2016-05-27
- Data Source
  KAKENHI-PROJECT-15K20051
[Presentation] Possible Mechanism of Neuroinflammation Induced by Surgical Procedure in the Mouse Hippocampus Determined by Using Transcriptome Analysis2015
- Author(s)
  Shunsuke Tachibana
- Organizer
  ASA annual meeting
- Place of Presentation
  San Diego,USA
- Year and Date
  2015-10-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20051

1. 西原教晃 (70836436)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. 田中聡一 (20969290)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. Yamakage Michiaki (70285005)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Tachibana Shunsuke 立花 俊祐

Research Projects

Research Products

Co-Researchers

A novel strategy for postoperative delirium control focusing on Irisin administration -protection the brain frailtyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

SIRT6 activation can prevent for exacerbating perioperative frailty : A Novel Strategy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of a strategy to prevent postoperative delirium with the stability of the intestinal microbiota

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

How to reduce anesthesia and surgical invasions in the frail brain - Strategies via gut microbiota regulationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Prevention strategies for perioperative neuroinflammation related diseases with a focus on stabilization of intestinal microbiota

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the link between the environmental change in the intestinal flora and cognitive decline due to anesthetic surgeryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism of postoperative cognitive dysfunction through epigeneticsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 麻酔科医として術後認知機能障害を俯瞰する2018

Author(s)

Journal Title

Data Source

[Presentation] デクスメデトミジンは、高齢マウスにおいて手術侵襲由来のMapt発現増大を抑制し、術後の認知機能低下を減弱する。2019

Author(s)

Organizer

Data Source

[Presentation] Dexmedetomidine attenuates up-regulation of the Rtn4rl2 gene and restores down-regulation of the Syt1 gene induced by sevoflurane/surgery stress in the hippocampus of elderly mice2018

Author(s)

Organizer

Data Source

[Presentation] Dexmedetomidine attenuates up-regulation of the Rtn4rl2 gene and restores down-regulation of the Syt1 gene induced by sevoflurane/surgery stress in the hippocampus of elderly mice2018

Author(s)

Organizer

Data Source

[Presentation] トランスクリプトーム解析を用いた術後認知機能障害の機序解明2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Possible Mechanism of Neuroinflammation Induced by Surgical Procedure in the Mouse Hippocampus Determined by Using Transcriptome Analysis2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Tachibana Shunsuke 立花俊祐