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LAI Chen-Yi  頼 貞儀

ORCIDConnect your ORCID iD *help
Researcher Number 30739925
Affiliation (based on the past Project Information) *help 2016 – 2017: 東京大学, 医科学研究所, 特任助教
2015: 東京大学, 医科学研究所, 特任研究員
Review Section/Research Field
Principal Investigator
General medical chemistry / Collagenous pathology/Allergology
Except Principal Investigator
Pediatrics / Experimental pathology
Keywords
Principal Investigator
慢性肉芽腫症 / CGD / Autoinflammation / intestine organoid / autoinflammation / 慢性肉芽腫
Except Principal Investigator
ゲノム編集 / 人工多能性幹細胞 / 生体分子 / 免疫学 … More / 先天性免疫不全症 / 遺伝子発現調節 / ウイルスベクター / 遺伝子治療 / 同種造血細胞移植 / 移植片対宿主病 / 移植 / 造血幹細胞 Less
  • Research Projects

    (4 results)
  • Research Products

    (6 results)
  • Co-Researchers

    (7 People)
  •  Ex vivo stem cell fate decision and oxidative stress status in chronic granulomatous diseasePrincipal Investigator

    • Principal Investigator
      頼 貞儀
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General medical chemistry
    • Research Institution
      The University of Tokyo
  •  Studies necessary to establish ideal HSC gene therapy for Wiskott Aldrich Syndrome

    • Principal Investigator
      大津 真
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      The University of Tokyo
  •  Mechanism of autoinflammation in chronic granulomatous disease: the molecular crosstalk between innate immune cells and gastrointestinal environmentsPrincipal Investigator

    • Principal Investigator
      Lai Chen-Yi
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Collagenous pathology/Allergology
    • Research Institution
      The University of Tokyo
  •  Immune suppressive function of allogeneic hematopoietic stem cells

    • Principal Investigator
      Otsu Makoto
    • Project Period (FY)
      2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Experimental pathology
    • Research Institution
      The University of Tokyo

All 2017 2015

All Journal Article Presentation

  • [Journal Article] 1.An All-Recombinant Protein-Based Culture System Specifically Identifies Hematopoietic Stem Cell Maintenance Factors.2017

    • Author(s)
      Ieyasu A, Ishida R, Kimura T, Morita M, Wilkinson AC, Sudo K, Nishimura T, Ohehara J, Tajima Y, Lai CY, Otsu M, Nakamura Y, Ema H, Nakauchi H, Yamazaki S
    • Journal Title

      Stem Cell Reports

      Volume: 14 Issue: 3 Pages: 500-508

    • DOI

      10.1016/j.stemcr.2017.01.015

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25713037, KAKENHI-PROJECT-15K20949, KAKENHI-PROJECT-16K15501, KAKENHI-PROJECT-16H02661, KAKENHI-PROJECT-17H05086
  • [Journal Article] Pre-Transplantation Blockade of TNF-α-Mediated Oxygen Species Accumulation Protects Hematopoietic Stem Cells.2017

    • Author(s)
      Ishida T, Suzuki S, Lai CY, Yamazaki S, Kakuta S, Iwakura Y, Nojima M, Takeuchi Y, Higashihara M, Nakauchi H, Otsu M.
    • Journal Title

      Stem Cells.

      Volume: 35 Issue: 4 Pages: 989-1002

    • DOI

      10.1002/stem.2524

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-16H02661, KAKENHI-PROJECT-25713037, KAKENHI-PROJECT-15K20949
  • [Presentation] Evaluation of the Utility of Induced Pluripotent Stem Cells as a Platform for Modeling Wiskott Aldrich Syndrome2017

    • Author(s)
      Honda-Ozaki F., Lin H.T., Lai C.Y., Otsu M
    • Organizer
      第46回日本免疫学会
    • Data Source
      KAKENHI-PROJECT-17H04225
  • [Presentation] Reevaluation of the utility of induced pluripotent stem cells as a model for Wiskott Aldrich Syndrome2017

    • Author(s)
      Honda-Ozaki F., Lin H.T., Okumra T., Lai C.Y., Otsu M
    • Organizer
      第23回日本遺伝子細胞治療学会
    • Data Source
      KAKENHI-PROJECT-17H04225
  • [Presentation] 骨髄炎症下における造血幹細胞保護2015

    • Author(s)
      石田 隆、鈴木幸恵、Chen-Yi Lai、角田 茂、岩倉 洋一郎、野島 正寛、竹内康雄、東原正明、中内啓光、大津 真
    • Organizer
      第80回日本インターフェロン・サイトカイン学会
    • Place of Presentation
      東京工業大学蔵前会館蔵前ホール(東京都目黒区)
    • Year and Date
      2015-07-17
    • Data Source
      KAKENHI-PROJECT-15K15109
  • [Presentation] Roles for Cxcr4 signaling in murine hematopoietic stem/progenitor cells in bone marrow repopulation2015

    • Author(s)
      Chen-Yi Lai
    • Organizer
      第80回日本インターフェロン・サイトカイン学会
    • Place of Presentation
      東京工業大学蔵前会館(東京都目黒区)
    • Year and Date
      2015-07-17
    • Data Source
      KAKENHI-PROJECT-15K20949
  • 1.  Otsu Makoto (30361330)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 2.  TAKAHASHI Satoshi (60226834)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  小野寺 雅史 (10334062)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  森尾 友宏 (30239628)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  ISHIDA Takashi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  山崎 聡
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  岩倉 洋一郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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