Hirai Keita 平井啓太

Researcher Number	30740203
Other IDs	https://orcid.org/0000-0001-8027-3508
Affiliation (Current)	2025: 信州大学, 学術研究院医学系(医学部附属病院), 准教授
Affiliation (based on the past Project Information) *help	2025: 信州大学, 学術研究院医学系(医学部附属病院), 准教授 2022 – 2023: 信州大学, 学術研究院医学系(医学部附属病院), 准教授 2022: 信州大学, 医学部, 准教授 2019 – 2021: 静岡県立大学, 薬学部, 講師 2016 – 2018: 静岡県立大学, 薬学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 47060:Clinical pharmacy-related / Medical pharmacy Except Principal Investigator Basic Section 47060:Clinical pharmacy-related / Medical pharmacy
Keywords	Principal Investigator 慢性閉塞性肺疾患 / 喘息 / ステロイド抵抗性 / バイオマーカー / 気管支喘息 / マイクロRNA / 遺伝子発現解析 / 治療有効性 / COPD / 慢性呼吸器疾患 … More / 個別化医療 / クラスター解析 / ヘルパーT細胞 / NOS2 / microRNA / 喘息・COPD オーバーラップ / 遺伝子多型 / 重症喘息 / 喘息・COPDオーバーラップ … More Except Principal Investigator 乳がん / 細胞外マトリクス / 抗体医薬 / CSPG4 / 個別化医療 / DNAアプタマー / 血中濃度モニタリング / 個別化薬物療法 / 血漿中濃度 / 予後予測 / 早期診断 / 腫瘍マーカー / CSPG4自己抗体 / がんの予後モニタリング / がんの早期診断 / コンドロイチン硫酸プロテオグリカン4 / がん診断・予後モニタリング / 自己抗体 / がん関連抗原 / エピトープペプチド / ヒト型抗体 / 細胞外マトリックス / メラノーマ / リコンビナントFab / ADCC活性 / 悪性中皮腫 / すい臓がん / IgG / がん免疫組織化学 / がん分子標的治療 Less

難治性喘息患者の最適な治療選択を志向した治療応答性マーカーの構築研究Principal Investigator
- Principal Investigator
  
  平井啓太
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Shinshu University
喘息・COPD患者の包括的な治療応答性評価に基づくプレシジョンメディスンの構築Principal Investigator
- Principal Investigator
  
  平井啓太
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Shinshu University
Clinical pharmacokinetic analysis of antibody drugs by application of innovative measurement techniques directed to personalized medicine
- Principal Investigator
  
  Hayashi Hideki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Gifu Pharmaceutical University
Construction of early diagnosis and prognosis prediction system by monitoring of cancer-related antigen CSPG4 specific autoantibodies.
- Principal Investigator
  
  ITOH Kunihiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  University of Shizuoka
Development of predictive markers of drug response for precision medicine in COPD patientsPrincipal Investigator
- Principal Investigator
  
  Hirai Keita
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  University of Shizuoka
Development of cancer therapeutic strategies targeting for extracellular matrix CSPG4.
- Principal Investigator
  
  ITOH Kunihiko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  University of Shizuoka
Development of precision medicine for patients with asthma and chronic obstructive pulmonary diseasePrincipal Investigator
- Principal Investigator
  
  Hirai Keita
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  University of Shizuoka

All 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Benralizumab restores gene and microRNA expression involved in steroid sensitivity in severe asthma2021
- Author(s)
  Hirai Keita、Uehara Sekiko、Shirai Toshihiro、Rachi Yuuka、Kimura Tomoki、Akamatsu Taisuke、Itoh Kunihiko
- Journal Title
  
  Allergy
  
  Volume: 76 Issue: 8 Pages: 2589-2592
- DOI
  10.1111/all.14819
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16450
[Journal Article] Annual changes in forced oscillation technique parameters correlate with FEV1 decline in patients with asthma, COPD, and asthma-COPD overlap2020
- Author(s)
  Tanaka Yuko、Hirai Keita、Nakayasu Hiromasa、Tamura Kanami、Masuda Toshihiro、Takahashi Shingo、Watanabe Hirofumi、Kishimoto Yutaro、Ohishi Kyouhei、Saigusa Mika、Akamatsu Taisuke、Yamamoto Akito、Morita Satoru、Asada Kazuhiro、Shirai Toshihiro
- Journal Title
  
  Allergol. Int.
  
  Volume: 69 Issue: 4 Pages: 626-627
- DOI
  10.1016/j.alit.2020.03.013
- NAID
  130007926265
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16450
[Journal Article] Circulating microRNA‐15b‐5p as a biomarker for asthma‐COPD overlap2020
- Author(s)
  Hirai Keita、Shirai Toshihiro、Shimoshikiryo Takayuki、Ueda Megumi、Gon Yasuhiro、Maruoka Shuichiro、Itoh Kunihiko
- Journal Title
  
  Allergy
  
  Volume: 76 Issue: 3 Pages: 766-774
- DOI
  10.1111/all.14520
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07482, KAKENHI-PROJECT-19K16450
[Journal Article] Oscillometry improves earlier than spirometry after benralizumab initiation in severe asthma2020
- Author(s)
  Shirai Toshihiro、Akamatsu Taisuke、Hirai Keita、Watanabe Hirofumi、Tamura Kanami、Kishimoto Yutaro、Saigusa Mika
- Journal Title
  
  Allergy
  
  Volume: - Issue: 10 Pages: 2678-2680
- DOI
  10.1111/all.14339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16450
[Journal Article] Forced oscillation technique may identify severe asthma2019
- Author(s)
  Shirai Toshihiro、Hirai Keita、Gon Yasuhiro、Maruoka Shuichiro、Mizumura Kenji、Hikichi Mari、Itoh Kunihiko、Hashimoto Shu
- Journal Title
  
  The Journal of Allergy and Clinical Immunology: In Practice
  
  Volume: 7 Issue: 8 Pages: 2857-2860.e1
- DOI
  10.1016/j.jaip.2019.05.036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07482, KAKENHI-PROJECT-19K16450
[Journal Article] Combined assessment of serum periostin and YKL-40 may identify asthma-COPD overlap2019
- Author(s)
  Shirai Toshihiro, Hirai Keita, Gon Yasuhiro, Maruoka Shuichiro, Mizumura Kenji, Hikichi Mari, Holweg Cecile, Itoh Kunihiko, Inoue Hiromasa, Hashimoto Shu
- Journal Title
  
  The Journal of Allergy and Clinical Immunology: In Practice
  
  Volume: 7 Issue: 1 Pages: 134-145
- DOI
  10.1016/j.jaip.2018.06.015
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18949
[Journal Article] Forced oscillation technique may identify asthma-COPD overlap2019
- Author(s)
  Shirai Toshihiro, Hirai Keita, Gon Yasuhiro, Maruoka Shuichiro, Mizumura Kenji, Hikichi Mari, Itoh Kunihiko, Hashimoto Shu
- Journal Title
  
  Allergol. Int.
  
  Volume: 68 Issue: 3 Pages: 385-387
- DOI
  10.1016/j.alit.2019.01.002
- NAID
  130007678494
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K18949
[Journal Article] Impact of Gene Expression Associated with Glucocorticoid-Induced Transcript 1 (GLCCI1) on Severe Asthma and Future Exacerbation2019
- Author(s)
  Hirai Keita、Shirai Toshihiro、Rachi Yuuka、Uehara Sekiko、Ueda Megumi、Nakatani Eiji、Itoh Kunihiko
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 42 Issue: 10 Pages: 1746-1752
- DOI
  10.1248/bpb.b19-00476
- NAID
  130007722397
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2019-10-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16450
[Journal Article] BIOMARKERS FOR PREDICTING FUTURE EXACERBATIONS IN ADULT PATIENTS WITH ASTHMA2019
- Author(s)
  平井啓太、白井敏博、伊藤邦彦
- Journal Title
  
  Japanese Journal of Allergology
  
  Volume: 68 Issue: 8 Pages: 942-947
- DOI
  10.15036/arerugi.68.942
- NAID
  130007709339
- ISSN
  0021-4884, 1347-7935
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16450
[Journal Article] Development of Stratified and Personalized Medicine Based on Pharmacogenomic and Pharmacokinetic Analyses2019
- Author(s)
  Hirai Keita
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 139 Issue: 10 Pages: 1253-1258
- DOI
  10.1248/yakushi.19-00145
- NAID
  130007721896
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2019-10-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16450
[Journal Article] Comparison of the Association between Circulating Vitamin D<sub>3</sub> Levels and Clinical Outcomes in Patients with Asthma and Chronic Obstructive Pulmonary Disease: A Prospective Observational Study2019
- Author(s)
  Hirai Keita、Shirai Toshihiro、Suzuki Yuya、Shimomura Tatsuki、Itoh Kunihiko
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 42 Issue: 11 Pages: 1861-1866
- DOI
  10.1248/bpb.b19-00385
- NAID
  130007740609
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2019-11-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16450
[Journal Article] Association between (CCTTT)n repeat polymorphism in NOS2 promoter and asthma exacerbations2018
- Author(s)
  Hirai Keita、Shirai Toshihiro、Suzuki Masayuki、Shimomura Tatsuki、Itoh Kunihiko
- Journal Title
  
  Journal of Allergy and Clinical Immunology
  
  Volume: 印刷中 Issue: 2 Pages: 663-665
- DOI
  10.1016/j.jaci.2018.02.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K18949
[Journal Article] A clustering approach to identify and characterize the asthma and chronic obstructive pulmonary disease overlap phenotype2017
- Author(s)
  Hirai K.、Shirai T.、Suzuki M.、Akamatsu T.、Suzuki T.、Hayashi I.、Yamamoto A.、Akita T.、Morita S.、Asada K.、Tsuji D.、Inoue K.、Itoh K.
- Journal Title
  
  Clinical & Experimental Allergy
  
  Volume: 47 Issue: 11 Pages: 1374-1382
- DOI
  10.1111/cea.12970
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K18949
[Presentation] ステロイド抵抗性喘息とマイクロRNA2023
- Author(s)
  平井啓太
- Organizer
  第72回日本アレルギー学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K06772
[Presentation] 重症喘息患者におけるステロイド反応性の低下機序2023
- Author(s)
  上原星輝子, 平井啓太, 白井敏博, 赤松泰介, 伊藤邦彦
- Organizer
  第72回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-22K06772
[Presentation] Treatable traitsとは？閉塞性肺疾患患者の治療層別化に向けたバイオマーカー構築の重要性2022
- Author(s)
  平井啓太
- Organizer
  第38回日本TDM学会・学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16450
[Presentation] 喘息およびCOPD患者の治療層別化マーカーの構築研究2022
- Author(s)
  平井啓太
- Organizer
  第62回日本呼吸器学会学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16450
[Presentation] 好酸球性気道炎症の病態から考える生物学的製剤の選択2021
- Author(s)
  白井敏博, 平井啓太
- Organizer
  第70回日本アレルギー学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16450
[Presentation] 薬物療法の層別化・個別化に向けたバイオマーカー構築の重要性2021
- Author(s)
  平井啓太
- Organizer
  第37回日本TDM学会・学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16450
[Presentation] High serum EDN levels may be a predictive biomarker for the responsiveness of benralizumab treatment2021
- Author(s)
  Uehara S, Hirai K, Shirai T, Akamatsu T, Itoh K.
- Organizer
  25th Annual Congress of the Asian Pacific Society of Respirology (APSR 2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16450
[Presentation] 重症喘息患者におけるステロイド抵抗性関連分子に対する生物学的製剤の影響2021
- Author(s)
  平井啓太
- Organizer
  第3回日本アレルギー学会東海地方会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16450
[Presentation] 薬剤師による研究~薬物治療に貢献する強力な一手~2021
- Author(s)
  平井啓太
- Organizer
  医療薬学フォーラム2021
- Invited
- Data Source
  KAKENHI-PROJECT-19K16450
[Presentation] 重症喘息患者におけるステロイド感受性関連分子に対するベンラリズマブの影響2021
- Author(s)
  平井啓太、上原星輝子、白井敏博、良知優花、木村朋起、赤松泰介、伊藤邦彦
- Organizer
  第61回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K16450
[Presentation] プレシジョンメディスンの実現を目指した治療層別化マーカーの構築2021
- Author(s)
  平井啓太
- Organizer
  日本薬学会第142年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16450
[Presentation] Annual change in forced oscillation technique correlates with FEV1 decline in patients with asthma, COPD, and asthma-COPD overlap2020
- Author(s)
  Yuko Tanaka, Keita Hirai, Hiromasa Nakayasu, Kanami Tamura, Toshihiro Masuda, Shingo Takahashi, Hirofumi Watanabe, Yutaro Kishimoto, Kyohei Oishi, Mika Saigusa, Taisuke Akamatsu, Akito Yamamoto, Satoru Morita, Kazuhiro Asada, Toshihiro Shirai
- Organizer
  American Academy of Allergy, Asthma & Immunology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16450
[Presentation] Effectiveness of benralizumab in patients with severe asthma2020
- Author(s)
  Hirofumi Watanabe, Taisuke Akamatsu, Keita Hirai, Hiromasa Nakayasu, Kanami Tamura, Toshihiro Masuda, Shingo Takahashi, Yuko Tanaka, Yutaro Kishimoto, Kyohei Oishi, Mika Saigusa, Akito Yamamoto, Satoru Morita, Kazuhiro Asada, Toshihiro Shirai
- Organizer
  American Academy of Allergy, Asthma & Immunology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16450
[Presentation] Benralizumab restored expression of key molecules involved in steroid-resistance in patients with severe asthma2020
- Author(s)
  Keita Hirai, Toshihiro Shirai, Taisuke Akamatsu, Sekiko Uehara, Yuka Rachi, Kanami Tamura, Yutaro Kishimoto, Mika Saigusa, Kazuhiro Asada, Kunihiko Itoh
- Organizer
  European Respiratory Society (ERS) International Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16450
[Presentation] Forced oscillation technique may identify severe asthma2019
- Author(s)
  Shirai Toshihiro, Hirai Keita, Gon Yasuhiro, Maruoka Shuichiro, Mizumura Kenji, Hikichi Mari, Itoh Kunihiko, Hashimoto Shu
- Organizer
  European Respiratory Society International Congress 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18949
[Presentation] NLRP3インフラマソーム遺伝子多型と喘息の病態との関連2019
- Author(s)
  鈴木裕也、平井啓太、良知優花、白井敏博、伊藤邦彦
- Organizer
  日本薬学会東海支部総会・大会
- Data Source
  KAKENHI-PROJECT-19K16450
[Presentation] SPG4 is a promising marker for immunohistochemical detection of breast cancer, including triple negative breast cancer2019
- Author(s)
  Kunihiko Itoh, Keita Hirai, Hisashi Yoshimura, and Toshiyuki Ishiwata
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K08375
[Presentation] CSPG4はトリプルネガティブ乳がんを含めた乳がんの免疫組織化学的検出における有望なマーカーである2019
- Author(s)
  伊藤邦彦、平井啓太、吉村久志、石渡俊行
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07197
[Presentation] Asthma-COPD Overlapの診断における血清ペリオスチン, YKL-40測定の意義2019
- Author(s)
  12.平井啓太、白井敏博、權寧博、丸岡秀一郎、水村賢司、引地麻梨、Cecile Holweg、伊藤邦彦、井上博雅、橋本修
- Organizer
  第49回吸入療法研究会
- Data Source
  KAKENHI-PROJECT-19K16450
[Presentation] 慢性呼吸器疾患患者における血中ビタミンD濃度と健康関連QOLおよび病態との関連2019
- Author(s)
  鈴木裕也、平井啓太、下村建貴、良知優花、白井敏博、伊藤邦彦
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16K18949
[Presentation] 重症喘息におけるglucocorticoid induced 1 (GLCCI1) 遺伝子多型および遺伝子発現量の関与2019
- Author(s)
  平井啓太、白井敏博、良知優花、上原星輝子、植田萌美、伊藤邦彦
- Organizer
  第59回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-16K18949
[Presentation] 細胞外マトリックスCSPG4の各種がん組織での発現2019
- Author(s)
  伊藤邦彦、志田幸平、青山春菜、鈴木詩絵里、平井啓太、吉村久志、石渡俊行
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16K08375
[Presentation] 血漿中microRNAを用いた喘息・COPDオーバーラップ (ACO) 病態マーカーの構築2019
- Author(s)
  平井啓太、白井敏博、權寧博、下敷領貴之、植田萌美、伊藤邦彦
- Organizer
  第68回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-16K18949
[Presentation] 喘息およびCOPDのプレシジョンメディスンの実現を目指した病態解析研究2019
- Author(s)
  平井啓太
- Organizer
  第13回次世代を担う若手医療薬科学シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19K16450
[Presentation] 喘息およびCOPD患者における1-メチルアデノシン濃度測定の意義2018
- Author(s)
  平井啓太、白井敏博、岸山和樹、山部喬之、秋山紗記子、下敷領貴之、伊藤邦彦
- Organizer
  第58回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-16K18949
[Presentation] Usefulness of the Forced Oscillation Technique in Diagnosing Asthma- COPD Overlap2018
- Author(s)
  Toshihiro Shirai, Keita Hirai, Yasuhiro Gon, Shuichiro Maruoka, Kenji Mizumura, Kunihiko Itoh, Shu Hashimoto
- Organizer
  American Thoracic Society International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18949
[Presentation] 喘息患者における増悪発現とNOS2遺伝子多型との関連2018
- Author(s)
  平井啓太、白井敏博、鈴木将之、下村建貴、伊藤邦彦
- Organizer
  第67回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-16K18949
[Presentation] 喘息患者の増悪発現に関わる分子病態および遺伝的因子の探索2018
- Author(s)
  平井啓太、白井敏博、植田萌美、良知優花、伊藤邦彦
- Organizer
  第17回 Kinki Hokuriku Airway disease Conference
- Data Source
  KAKENHI-PROJECT-16K18949
[Presentation] 喘息・COPDオーバラップの病態解析におけるmicro-RNAの有用性2018
- Author(s)
  植田萌美、平井啓太、下敷領貴之、白井敏博、伊藤邦彦
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K18949
[Presentation] 喘息・COPDオーバーラップ (ACO) の病態解析と特異的バイオマーカーの構築2018
- Author(s)
  平井啓太、白井敏博、権寧博、伊藤邦彦、橋本修
- Organizer
  第27回Pneumo Forum
- Data Source
  KAKENHI-PROJECT-16K18949
[Presentation] 喘息患者の増悪発現に関わる分子病態および遺伝的因子の解明2017
- Author(s)
  平井啓太、白井敏博、下敷領貴之、植田萌美、伊藤邦彦
- Organizer
  第63回日本薬学会東海支部総会・大会
- Data Source
  KAKENHI-PROJECT-16K18949
[Presentation] クラスタ解析による喘息・COPDオーバーラップ症候群における診断マーカーの構築2017
- Author(s)
  平井啓太、白井敏博、鈴木将之、植田萌美、辻大樹、井上和幸、伊藤邦彦
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-16K18949
[Presentation] Association between pentanucleotide repeat polymorphism in NOS2 promoter and asthma exacerbations.2017
- Author(s)
  Keita Hirai, Toshihiro Shirai, Masayuki Suzuki, Daiki Tsuji, Kazuyuki Inoue, Kunihiko Itoh
- Organizer
  European Respiratory Society International Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18949
[Presentation] 喘息および慢性閉塞性肺疾患患者における唾液中1-メチルアデノシン濃度測定の意義2017
- Author(s)
  平井啓太、白井敏博、岸山和樹、山部喬之、秋山紗記子、下敷領貴之、伊藤邦彦
- Organizer
  第11回次世代を担う若手医療薬科学シンポジウム
- Data Source
  KAKENHI-PROJECT-16K18949
[Presentation] Comparable serum periostin levels among a Japanese population with asthma, COPD, and asthma-COPD overlap.2017
- Author(s)
  Toshihiro Shirai, Keita Hirai, Yasuhiro Gon, Hiromasa Inoue, Shu Hashimoto
- Organizer
  European Respiratory Society International Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18949
[Presentation] T細胞特異的転写因子発現解析による喘息・COPDオーバーラップ症候群の病態解析2016
- Author(s)
  平井啓太、白井敏博、赤松泰介、鈴木貴人、林一郎、山本輝人、秋田剛史、森田悟、朝田和博、伊藤邦彦
- Organizer
  第15回Kinki Hokuriku Airway disease Conference
- Place of Presentation
  大阪
- Year and Date
  2016-04-03
- Data Source
  KAKENHI-PROJECT-16K18949
[Presentation] Usefulness of the forced oscillation technique in diagnosing asthma-COPD overlap syndrome2016
- Author(s)
  Toshihiro Shirai, Keita Hirai, Taisuke Akamatsu, Takahito Suzuki, Ichiro Hayashi, Akito Yamamoto, Takefumi Akita, Satoru Morita, Kazuhiro Asada
- Organizer
  European Respiratory Society International Congress 2016
- Place of Presentation
  London
- Year and Date
  2016-09-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18949
[Presentation] エンドタイプ解析に基づいた喘息・COPDオーバーラップ症候群の病態解析2016
- Author(s)
  平井啓太、白井敏博、赤松泰介、鈴木貴人、林一郎、山本輝人、秋田剛史、森田悟、朝田和博、伊藤邦彦
- Organizer
  第90回閉塞性肺疾患研究会
- Place of Presentation
  東京
- Year and Date
  2016-07-16
- Data Source
  KAKENHI-PROJECT-16K18949

1. ITOH Kunihiko (90221770)

# of Collaborated Projects: 4 results

# of Collaborated Products: 23 results
2. 井上和幸 (90514589)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 辻大樹 (90565615)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 白井敏博 (50522760)

# of Collaborated Projects: 2 results

# of Collaborated Products: 22 results
5. Hayashi Hideki (00419665)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 大野康 (00334938)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 飯原大稔 (40775095)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 轟木堅一郎 (70341451)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 鈴木昭夫 (80775148)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 権寧博 (80339316)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. Gon Yasuhiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
12. Hashimoto Shu

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
13. 丸岡秀一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Hirai Keita 平井 啓太

Research Projects

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Co-Researchers

難治性喘息患者の最適な治療選択を志向した治療応答性マーカーの構築研究Principal Investigator

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喘息・COPD患者の包括的な治療応答性評価に基づくプレシジョンメディスンの構築Principal Investigator

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Clinical pharmacokinetic analysis of antibody drugs by application of innovative measurement techniques directed to personalized medicine

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Construction of early diagnosis and prognosis prediction system by monitoring of cancer-related antigen CSPG4 specific autoantibodies.

Principal Investigator

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Development of predictive markers of drug response for precision medicine in COPD patientsPrincipal Investigator

Principal Investigator

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Development of cancer therapeutic strategies targeting for extracellular matrix CSPG4.

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Development of precision medicine for patients with asthma and chronic obstructive pulmonary diseasePrincipal Investigator

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[Journal Article] Benralizumab restores gene and microRNA expression involved in steroid sensitivity in severe asthma2021

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[Journal Article] Annual changes in forced oscillation technique parameters correlate with FEV1 decline in patients with asthma, COPD, and asthma-COPD overlap2020

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[Journal Article] Circulating microRNA‐15b‐5p as a biomarker for asthma‐COPD overlap2020

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[Journal Article] Oscillometry improves earlier than spirometry after benralizumab initiation in severe asthma2020

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[Journal Article] Forced oscillation technique may identify severe asthma2019

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[Journal Article] Combined assessment of serum periostin and YKL-40 may identify asthma-COPD overlap2019

Author(s)

Journal Title

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Data Source

[Journal Article] Forced oscillation technique may identify asthma-COPD overlap2019

Hirai Keita 平井啓太

[Presentation] Treatable traitsとは？閉塞性肺疾患患者の治療層別化に向けたバイオマーカー構築の重要性2022