• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Okita Yukari  沖田 結花里

ORCIDConnect your ORCID iD *help
… Alternative Names

OKITA Yukari  沖田 結花里

Less
Researcher Number 30743710
Other IDs
Affiliation (Current) 2025: 筑波大学, 医学医療系, 助教
Affiliation (based on the past Project Information) *help 2025: 筑波大学, 医学医療系, 助教
2017 – 2023: 筑波大学, 医学医療系, 助教
2015 – 2016: 筑波大学, 医学医療系, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 50010:Tumor biology-related / Tumor biology / Experimental pathology
Except Principal Investigator
Experimental pathology
Keywords
Principal Investigator
腫瘍形成 / GPNMB / がん幹細胞 / EMT / 細胞運動 / スフェア形成 / 環状ペプチド / 分子標的治療 / 転移形成 / MafK … More / TGF-β / 上皮間葉転換 / 幹細胞マーカー / 抗体 / 特殊環状ペプチド / 乳がん / Gpnmb … More
Except Principal Investigator
Gpnmb / 幹細胞 / 上皮間葉転換 / MAFK / 特殊環状ペプチド / GPNMB / MafK / TMEPAI / TGF-β / トランスフォーミング増殖因子β / がん幹細胞 / 足場非依存性増殖 / がん Less
  • Research Projects

    (6 results)
  • Research Products

    (43 results)
  • Co-Researchers

    (4 People)
  •  GPNMBによるがん幹細胞性誘導と可塑性に関する研究Principal Investigator

    • Principal Investigator
      沖田 結花里
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      University of Tsukuba
  •  Role of glycoprotein NMB in cancer stemness inductionPrincipal Investigator

    • Principal Investigator
      沖田 結花里
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      University of Tsukuba
  •  Role of TGF-beta related molecules in tumorigenesis through cancer stemness inductionPrincipal Investigator

    • Principal Investigator
      Okita Yukari
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      University of Tsukuba
  •  Roles of GPNMB in cancer stem cells and development of therapeutic agent targeting GPNMBPrincipal Investigator

    • Principal Investigator
      Okita Yukari
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Tumor biology
    • Research Institution
      University of Tsukuba
  •  Roles of MafK-Gpnmb axis in malignant progression of cancer and molecular targeted therapyPrincipal Investigator

    • Principal Investigator
      OKITA Yukari
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Experimental pathology
    • Research Institution
      University of Tsukuba
  •  Roles of TGF-beta target genes TMEPAI and MafK on cancer development

    • Principal Investigator
      Kato Mitsuyasu
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      University of Tsukuba

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2013 Other

All Journal Article Presentation

  • [Journal Article] Glycoprotein nonmetastatic melanoma protein B impacts the malignant potential of bladder cancer cells through its hem‐immunoreceptor tyrosine‐based activation motif2024

    • Author(s)
      Kimura Tomokazu、Okita Yukari、Nagumo Yoshiyuki、Chin Jas Min、Fikry Muhammad Ali、Shiga Masanobu、Kandori Shuya、Kawahara Takashi、Suzuki Hiroyuki、Nishiyama Hiroyuki、Kato Mitsuyasu
    • Journal Title

      Pathology International

      Volume: - Issue: 5 Pages: 262-273

    • DOI

      10.1111/pin.13419

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K07184, KAKENHI-PROJECT-20K20597
  • [Journal Article] Glycoprotein NMB promotes tumor formation and malignant progression of laryngeal squamous cell carcinoma2022

    • Author(s)
      Manevich L, Okita Y, Okano Y, Sugasawa T, Kawanishi K, Poullikkas T, Dang Cao LTL, Zheng L, Nakayama M, Matsumoto S, Tabuchi K, Kato M
    • Journal Title

      Cancer Science

      Volume: - Issue: 9 Pages: 3244-3254

    • DOI

      10.1111/cas.15359

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07658, KAKENHI-PROJECT-20K20597
  • [Journal Article] Polyvinyl alcohol scaffolds and supplementation support 3D and sphere culturing of human cancer cell lines by reducing apoptosis and promoting cellular proliferation2021

    • Author(s)
      Okita Yukari、Zheng Ling、Kawanishi Kunio、Miyoshi Hirotoshi、Yanagihara Kazuyoshi、Kato Mitsuyasu
    • Journal Title

      Genes to Cells

      Volume: 26(5) Issue: 5 Pages: 336-343

    • DOI

      10.1111/gtc.12843

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07658, KAKENHI-PROJECT-20K20597, KAKENHI-PROJECT-19K17730, KAKENHI-PROJECT-20K16434, KAKENHI-PROJECT-18H02676
  • [Journal Article] Glycoprotein non-metastatic melanoma protein B functions with growth factor signaling to induce tumorigenesis through its serine phosphorylation2021

    • Author(s)
      Wang Chen、Okita Yukari、Zheng Ling、Shinkai Yasuhiro、Manevich Lev、Chin Jas M.、Kimura Tomokazu、Suzuki Hiroyuki、Kumagai Yoshito、Kato Mitsuyasu
    • Journal Title

      Cancer Science

      Volume: 112 Issue: 10 Pages: 4187-4197

    • DOI

      10.1111/cas.15090

    • NAID

      120007178942

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07473, KAKENHI-PROJECT-19K07658, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-20K20597
  • [Journal Article] Role of the kringle-like domain in glycoprotein NMB for its tumorigenic potential.2019

    • Author(s)
      Xie R, Okita Y, Ichikawa Y, Fikry MA, Huynh Dam KT, Tran STP, Kato M
    • Journal Title

      Cancer Science

      Volume: 110 Issue: 7 Pages: 2237-2246

    • DOI

      10.1111/cas.14076

    • NAID

      120007133159

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07658, KAKENHI-PROJECT-18H02676
  • [Journal Article] Glycoprotein nmb is exposed on the surface of dormant breast cancer cells and induces stem cell-like properties2018

    • Author(s)
      Chen Chen、Okita Yukari、Watanabe Yukihide、Abe Fumie、Fikry Muhammad Ali、Ichikawa Yumu、Suzuki Hiroyuki、Shibuya Akira、Kato Mitsuyasu
    • Journal Title

      Cancer Research

      Volume: 78 Issue: 22 Pages: 6424-6435

    • DOI

      10.1158/0008-5472.can-18-0599

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05022, KAKENHI-PROJECT-16H06387, KAKENHI-PROJECT-16K08706, KAKENHI-PROJECT-17K14981
  • [Journal Article] Cell-surface GPNMB and induction of stemness.2018

    • Author(s)
      Okita Y, Chen C, Kato M.
    • Journal Title

      Oncotarget

      Volume: 9(99) Issue: 99 Pages: 37289-37290

    • DOI

      10.18632/oncotarget.26472

    • Open Access
    • Data Source
      KAKENHI-PROJECT-18H02676, KAKENHI-PROJECT-17K14981
  • [Journal Article] The transcription factor MAFK induces EMT and malignant progression of triple-negative breast cancer cells through its target GPNMB2017

    • Author(s)
      Yukari Okita, Minori Kimura, Rudy Xie, Chen Chen, Larina Tzu-Wei Shen, Yurika Kojima, Hiroyuki Suzuki, Masafumi Muratani, Masao Saitoh, Kentaro Semba, Carl-Henrik Heldin, Mitsuyasu Kato
    • Journal Title

      Science Signaling

      Volume: 10 Issue: 474 Pages: 11-11

    • DOI

      10.1126/scisignal.aak9397

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19070, KAKENHI-PROJECT-16K08706, KAKENHI-PUBLICLY-15H01343, KAKENHI-PROJECT-15H05576
  • [Journal Article] Transforming growth factor-&βinduces transcription factors MafK and Bach1 to suppress expression of the heme oxygenase-1 gene.2013

    • Author(s)
      Okita Y, Kamoshida A, Suzuki H, Itoh K, Motohashi H, Igarashi K, Ogami T, Koinuma D, Kato M.
    • Journal Title

      J Biol Chem

      Volume: 288 Issue: 28 Pages: 20658-20667

    • DOI

      10.1074/jbc.m113.450478

    • NAID

      120007136878

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390066, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-25293092, KAKENHI-PROJECT-25460472, KAKENHI-PROJECT-25640059
  • [Presentation] 乳がんの進展におけるGPNMBの作用2024

    • Author(s)
      沖田結花里、加藤光保
    • Organizer
      第113回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-22K07184
  • [Presentation] 乳がんにおけるGPNMBとFGFRの相互作用2023

    • Author(s)
      エルヒナウィ マナール、沖田結花里、加藤光保
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K07184
  • [Presentation] 細胞運動性獲得におけるGPNMBの作用2023

    • Author(s)
      沖田結花里、加藤光保
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K07184
  • [Presentation] 乳がんにおけるglycoprotein NMBの役割2022

    • Author(s)
      沖田結花里、加藤光保
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K07184
  • [Presentation] 薬剤耐性における転写因子MAFKの作用2021

    • Author(s)
      八幡原礼音、 沖田結花里、加藤 光保
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K07658
  • [Presentation] 乳がん細胞の幹細胞性獲得におけるGPNMBの作用2020

    • Author(s)
      沖田結花里、加藤光保
    • Organizer
      第109回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-19K07658
  • [Presentation] 幹細胞性誘導によるがんの持続的増殖機構2020

    • Author(s)
      加藤光保、沖田結花里
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K07658
  • [Presentation] GPNMBによる幹細胞性誘導機構の解明2019

    • Author(s)
      沖田結花里、陳晨、加藤光保
    • Organizer
      第3回がん三次元培養研究会
    • Data Source
      KAKENHI-PROJECT-19K07658
  • [Presentation] 乳がんの発生・進展における転写因子MAFKとその標的遺伝子GPNMBの作用2018

    • Author(s)
      沖田結花里
    • Organizer
      第107回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-17K14981
  • [Presentation] 幹細胞性誘導による腫瘍形成機構2018

    • Author(s)
      加藤光保、陳晨、沖田結花里
    • Organizer
      第2回がん三次元培養研究会
    • Data Source
      KAKENHI-PROJECT-17K14981
  • [Presentation] 乳がん細胞におけるGPNMBの幹細胞性誘導作用2018

    • Author(s)
      沖田結花里、鈴木裕之、加藤光保
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K14981
  • [Presentation] 幹細胞性誘導によるがん細胞の持続的増加機構2018

    • Author(s)
      加藤光保、沖田結花里
    • Organizer
      第107回日本病理学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K14981
  • [Presentation] Glycoprotein nmbとがん幹細胞性2018

    • Author(s)
      沖田結花里、陳晨、加藤光保
    • Organizer
      第107回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-17K14981
  • [Presentation] 乳がん細胞の運動におけるGPNMBとFGF-2の作用2018

    • Author(s)
      市川優矛、沖田結花里、加藤光保
    • Organizer
      第107回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-17K14981
  • [Presentation] Kringle-like domain is essential in GPNMB-induced breast cancer formation2017

    • Author(s)
      Rudy Xie, Yukari Okita, and Mitsuyasu Kato
    • Organizer
      第40回日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-17K14981
  • [Presentation] Cell surface expression of GPNMB on dormant breast cancer stem cells2017

    • Author(s)
      Chen Chen, Yukari Okita, and Mitsuyasu Kato
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K14981
  • [Presentation] Mutual induction of GPNMB and LPAR1 in Breast Cancer2017

    • Author(s)
      Xinzhu Hong, Minori Kimura,Yukari Okita, and Mitsuyasu Kato
    • Organizer
      第106回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-17K14981
  • [Presentation] Norvel therapeutic strategy targeting GPNMB expressing dormant cancer cells2017

    • Author(s)
      Yukari Okita
    • Organizer
      TGF-β meeting in Uppsala 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K14981
  • [Presentation] 乳がんの発生・進展におけるGPNMBの役割2017

    • Author(s)
      沖田結花里、陳晨、加藤光保
    • Organizer
      第1回がん三次元培養研究会
    • Data Source
      KAKENHI-PROJECT-17K14981
  • [Presentation] 乳がんの発生・進展におけるGPNMBの役割2017

    • Author(s)
      沖田結花里、陳晨、鈴木裕之、加藤光保
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K14981
  • [Presentation] 転写因子MafKはTGF-βによって誘導され、腫瘍形成を促進する2016

    • Author(s)
      加藤光保、沖田結花里
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜 神奈川県 横浜市
    • Year and Date
      2016-10-06
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K19070
  • [Presentation] 乳がんにおけるGPNMBの役割2016

    • Author(s)
      沖田結花里、陳晨、鈴木裕之、加藤光保
    • Organizer
      第39回分子生物学会年会
    • Place of Presentation
      パシフィコ横浜 神奈川県 横浜市
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-15K19070
  • [Presentation] Roles of GPNMB in breast cancer initiation and malignant progression2016

    • Author(s)
      Yukari Okita, Ai Kato, Chen Chen, Hiroyuki Suzuki, and Mitsuyasu Kato
    • Organizer
      the 41st Naito Conference
    • Place of Presentation
      シャトレーゼ ガトーキングダム サッポロ 北海道 札幌市
    • Year and Date
      2016-07-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19070
  • [Presentation] Roles of GPNMB in breast cancer malignant formation and progression2016

    • Author(s)
      Yukari Okita, Hiroyuki Suzuki, and Mitsuyasu Kato
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜 神奈川県 横浜市
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15K19070
  • [Presentation] 乳がんの発生・進展におけるGPNMBの役割2016

    • Author(s)
      沖田結花里、鈴木裕之、加藤光保
    • Organizer
      第105回日本病理学会総会
    • Place of Presentation
      宮城県仙台市、仙台国際交流センター
    • Year and Date
      2016-05-12
    • Data Source
      KAKENHI-PROJECT-15K19070
  • [Presentation] Roles of GPNMB in Breast Cancer Stem Cells2016

    • Author(s)
      陳晨、沖田結花里、加藤光保
    • Organizer
      第39回分子生物学会年会
    • Place of Presentation
      パシフィコ横浜 神奈川県 横浜市
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-15K19070
  • [Presentation] 乳がんの発生・進展におけるGPNMBの役割2016

    • Author(s)
      沖田結花里、鈴木裕之、加藤光保
    • Organizer
      第105回日本病理学会総会
    • Place of Presentation
      仙台国際センター 宮城県 仙台市
    • Year and Date
      2016-05-12
    • Data Source
      KAKENHI-PROJECT-15K19070
  • [Presentation] 乳がんにおける転写因子MafKの働き2015

    • Author(s)
      沖田結花里、鈴木裕之、加藤光保
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-25293092
  • [Presentation] 乳がんにおける転写因子MafKの働き2015

    • Author(s)
      沖田結花里、鈴木裕之、加藤光保
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      愛知県名古屋市、名古屋国際会議場
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-15K19070
  • [Presentation] Transcription factor MafK induces epithelial-mesenchymal transition and malignant progression of breast cancer cells.2015

    • Author(s)
      Yukari Okita, Hiroyuki Suzuki and Mitsuyasu Kato
    • Organizer
      FASEB Science Research Conference
    • Place of Presentation
      Snowmass, Colorado
    • Year and Date
      2015-07-12
    • Data Source
      KAKENHI-PROJECT-25293092
  • [Presentation] Transcription factor MafK induces epithelial-mesenchymal transition and malignant progression of breast cancer cells2015

    • Author(s)
      Yukari Okita, Hiroyuki Suzuki, and Mitsuyasu Kato
    • Organizer
      FASEB meeting The TGF-β Superfamily: Signaling in Development and Disease
    • Place of Presentation
      アメリカ合衆国コロラド州
    • Year and Date
      2015-07-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19070
  • [Presentation] 乳腺細胞の上皮間葉転換と腫瘍形成における転写因子MafKの役割2013

    • Author(s)
      沖田結花里
    • Organizer
      第32回分子病理学研究会
    • Place of Presentation
      奈良
    • Data Source
      KAKENHI-PROJECT-25293092
  • [Presentation] 乳腺上皮細胞の上皮間葉転換と腫瘍形成における小Maf群転写因子の役割2013

    • Author(s)
      沖田結花里
    • Organizer
      第102回日本病理学会総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-25293092
  • [Presentation] 乳がんにおける転写因子MafKの役割

    • Author(s)
      沖田結花里
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-25293092
  • 1.  KATO Mitsuyasu (20194855)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 23 results
  • 2.  WATANABE Yukihide (40618534)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  鈴木 裕之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 4.  本橋 ほづみ
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi