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Huang Zhe  黄 哲

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… Alternative Names

黄 哲  コウ テツ

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Researcher Number 30745112
Other IDs
Affiliation (Current) 2025: 産業医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help 2023: 産業医科大学, 医学部, 助教
2020 – 2022: 名古屋大学, 医学系研究科, 特任講師
2015 – 2016: 産業医科大学, 医学部, 助教
Review Section/Research Field
Except Principal Investigator
Basic Section 52020:Neurology-related / Basic Section 52010:General internal medicine-related / Medium-sized Section 52:General internal medicine and related fields / Neurology
Keywords
Except Principal Investigator
サルコペニア / オートファジー / 凝集体形成抑制 / 病因蛋白質の選択的な分解 / 運動ニューロン疾患 / 神経変性 / カテプシン / 悪性腫瘍 / カテブシン / カテプシンK … More / 悪液質 / マウス / 老化制御 / エクソゾーム / 細胞治療 / 間葉系幹細胞 / 老化 / ユビキチンープロテアソーム系 / 筋萎縮性側索硬化症 / 球脊髄性筋萎縮症 / ポリグルタミン病 / HIKESHI / TFEB / ユビキチン・プロテアソーム系 / 分子シャペロン / 神経変性疾患 Less
  • Research Projects

    (4 results)
  • Research Products

    (13 results)
  • Co-Researchers

    (7 People)
  •  Reducing toxicity of disease-causative molecules with the aim of developing therapies for neurodegenerative diseases

    • Principal Investigator
      足立 弘明
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Research on mesenchymal stem cells and their exosomes as aging regulators

    • Principal Investigator
      Kuzuya Masafumi
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Nagoya University
  •  Research on cathepsin K as a new target for treatment of sarcopenia associated with cachexia

    • Principal Investigator
      葛谷 雅文
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Nagoya University
  •  Selective protein degradation with the aim of developing therapies for neurodegenarative diseases

    • Principal Investigator
      Adachi Hiroaki
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      University of Occupational and Environmental Health, Japan

All 2024 2023 2022 2021 2020 2016

All Journal Article Presentation Patent

  • [Journal Article] CSF 14-3-3 zeta(ζ) isoform is associated with tau pathology and cognitive decline in Alzheimer’s disease.2024

    • Author(s)
      Qiang Q, Skudder-Hill L, Toyota T, Huang Z, Wei W, Adachi H.
    • Journal Title

      J Neurol Sci

      Volume: 457 Pages: 122861-122861

    • DOI

      10.1016/j.jns.2023.122861

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K06976
  • [Journal Article] Cathepsin K activity controls cachexia-induced muscle atrophy via the modulation of IRS1 ubiquitination.2022

    • Author(s)
      Meng X, Huang Z, Inoue A, Wang H, Wan Y, Yue X, Xu S, Jin X, Shi GP, Kuzuya M, Cheng XW.
    • Journal Title

      J Cachexia Sarcopenia Muscle.

      Volume: 13(2) Issue: 2 Pages: 1197-1209

    • DOI

      10.1002/jcsm.12919

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03574
  • [Journal Article] Natural Compounds Preventing Neurodegenerative Diseases Through Autophagic Activation2016

    • Author(s)
      Huang Z, Adachi H.
    • Journal Title

      Journal of UOEH

      Volume: 38 Issue: 2 Pages: 139-148

    • DOI

      10.7888/juoeh.38.139

    • NAID

      130005157739

    • ISSN
      0387-821X, 2187-2864
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26293207
  • [Patent] 筋肉量の低下抑制に用いる細胞調製物2020

    • Inventor(s)
      成憲武、黄哲、朴麗梅、葛谷雅文、原田雅充
    • Industrial Property Rights Holder
      名古屋大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-20K21572
  • [Presentation] Kaempferol promotes the degradation of mutant proteins via a novel mTOR-dependent autophagic pathway2023

    • Author(s)
      足立 弘明、黄 哲、豊田 知子、勝野 雅央、祖父江 元
    • Organizer
      第64回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-23K06976
  • [Presentation] 神経変性疾患の病因蛋白質の分解亢進による予防2023

    • Author(s)
      足立弘明、黄 哲、豊田知子
    • Organizer
      第5回日本脳サプリメント学会
    • Data Source
      KAKENHI-PROJECT-23K06976
  • [Presentation] Kaempferol promotes the degradation of mutant proteins via a novel mTOR-dependent autophagic pathway2023

    • Author(s)
      足立 弘明、黄 哲、豊田 知子、勝野 雅央、祖父江 元
    • Organizer
      第46回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-23K06976
  • [Presentation] Kaempferol promotes the degradation of mutant proteins via a novel mTOR-dependent autophagic pathway2023

    • Author(s)
      Adachi H, Huang Z, Toyota T, Qiang Q, Katsuno M, Sobue G
    • Organizer
      Neuroscience 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K06976
  • [Presentation] ヒト臍帯由来間葉系幹細胞を用いたサルコペニア治療の可能性2021

    • Author(s)
      黄 哲
    • Organizer
      第8回日本サルコペニア・フレイル学会大会
    • Data Source
      KAKENHI-PROJECT-20K21572
  • [Presentation] オートファジーによる変異アンドロゲン受容体の分解とその治療への応用2016

    • Author(s)
      足立弘明、黄哲、岡田和将、大成圭子、橋本智代、岩中行己男、豊田知子、勝又 竜
    • Organizer
      第11回 臨床ストレス応答学会大会
    • Place of Presentation
      山口大学(山口県・山口市)
    • Year and Date
      2016-11-11
    • Data Source
      KAKENHI-PROJECT-26293207
  • [Presentation] TFEB and Hikeshi influence the degradation of the disease-causative proteins in cellular models of neurodegenerative diseases.2016

    • Author(s)
      Adachi H, Huang Z, Okada K, Ohnari K, Hashimoto T, Toyota T, Iwanakan Y, Sobue G.
    • Organizer
      Neuroscience 2016
    • Place of Presentation
      San Diego(米国)
    • Year and Date
      2016-11-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293207
  • [Presentation] Effects of the overexpression of TFEB in cellular models of neurodegenerative diseases2016

    • Author(s)
      Adachi H, Huang Z, Okada K, Ohnari K, Hashimoto T, Toyota T, Iwanakan Y
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-07-20
    • Data Source
      KAKENHI-PROJECT-26293207
  • [Presentation] Effects of the overexpression of TFEB in cellular models of neurodegenerative diseases2016

    • Author(s)
      Adachi H, Huang Z, Okada K, Ohnari K, Hashimoto T, Toyota T, Iwanakan Y
    • Organizer
      第57回日本神経学会学術大会
    • Place of Presentation
      神戸国際会議場(兵庫県・神戸市)
    • Year and Date
      2016-05-18
    • Data Source
      KAKENHI-PROJECT-26293207
  • 1.  Adachi Hiroaki (40432257)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 2.  Kuzuya Masafumi (10283441)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 3.  朴 麗梅 (60867208)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  岡田 和将 (30341499)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 5.  岩中 行己男 (60590461)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 6.  橋本 智代 (70425685)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 7.  豊田 知子 (30596432)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results

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