Aihara Masamune 相原正宗

Researcher Number	30748843
Other IDs
Affiliation (Current)	2025: 九州大学, 医学研究院, 講師
Affiliation (based on the past Project Information) *help	2023: 九州大学, 医学研究院, 講師 2021 – 2022: 九州大学, 大学病院, 臨床検査技師 2019 – 2020: 九州大学, 医学研究院, 講師 2017 – 2018: 九州大学, 大学病院, 臨床検査技師
Review Section/Research Field	Principal Investigator Basic Section 52010:General internal medicine-related / Laboratory medicine Except Principal Investigator Basic Section 59040:Nutrition science and health science-related
Keywords	Principal Investigator 全ゲノム / ゲノム進化 / ゲノム / 抗菌薬 / ゲノミクス / 宿主内ゲノム進化 / 細菌 / 薬剤耐性 / ATP / ミトコンドリアmRNA / Poly(A) / ミトコンドリア … More Except Principal Investigator … More タンパク質凝集 / ミトコンドリア Less

Reserch for within-host bacterial evolution leading to increased antimicrobial resistancePrincipal Investigator
- Principal Investigator
  
  Aihara Masamune
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kyushu University
Exploration of phenomena indicative of mitochondrial dysfunction and its applications
- Principal Investigator
  
  Matsushima Yuichi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kyushu University
Measurement of mitochondrial mRNA polyadenylation as a evaluation method for mitochondrial functionPrincipal Investigator
- Principal Investigator
  
  Aihara Masamune
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kyushu University

All 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] Polymyxin B nonapeptide を用いたカルバペネム低感受性腸内細菌目細菌における抗菌薬膜透過性低下の検出2023
- Author(s)
  相原正宗柳澤由佳子西凛佳子山下有加木部泰志清祐麻紀子堀田多恵子
- Journal Title
  
  日本臨床微生物学会雑誌
  
  Volume: 33 Pages: 296-301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03579
[Journal Article] Mitochondrial Lon protease is a gatekeeper for proteins newly imported into the matrix2021
- Author(s)
  Matsushima Yuichi、Takahashi Kazuya、Yue Song、Fujiyoshi Yuki、Yoshioka Hideaki、Aihara Masamune、Setoyama Daiki、Uchiumi Takeshi、Fukuchi Satoshi、Kang Dongchon
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1 Pages: 974-974
- DOI
  10.1038/s42003-021-02498-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00530, KAKENHI-PROJECT-18H03180, KAKENHI-PROJECT-21K19717
[Journal Article] Stepwise Evolution of a Klebsiella pneumoniae Clone within a Host Leading to Increased Multidrug Resistance2021
- Author(s)
  Yoshino Mai、Aihara Masamune、Gotoh Yasuhiro、Akimoto Masaru、Tatsuhara Wakana、Kiyosuke Makiko、Matsushima Yuichi、Uchiumi Takeshi、Hayashi Tetsuya、Kang Dongchon
- Journal Title
  
  mSphere
  
  Volume: 6 Issue: 6 Pages: 00734-21
- DOI
  10.1128/msphere.00734-21
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00530, KAKENHI-PROJECT-20H03579
[Journal Article] Within-host evolution of a Klebsiella pneumoniae clone: selected mutations associated with the alteration of outer membrane protein expression conferred multidrug resistance.2021
- Author(s)
  Aihara M, Nishida R, Akimoto M, Gotoh Y, Kiyosuke M, Uchiumi T, Nishioka M, Matsushima Y, Hayashi T, Kang D
- Journal Title
  
  J Antimicrob Chemother
  
  Volume: 76(2) Issue: 2 Pages: 362-369
- DOI
  10.1093/jac/dkaa439
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00530, KAKENHI-PROJECT-20H03579
[Journal Article] What is the best wavelength for the measurement of hemolysis index?2020
- Author(s)
  Ishiguro Akiyo、Nishioka Mitsuaki、Morishige Akihiro、Kawano Reo、Kobayashi Toshihiko、Fujinaga Aki、Takagi Fumiya、Kogo Tomihisa、Morikawa Yuki、Okayama Naoko、Mizuno Hidekazu、Aihara Masamune、Suehiro Yutaka、Yamasaki Takahiro
- Journal Title
  
  Clinica Chimica Acta
  
  Volume: 510 Pages: 15-20
- DOI
  10.1016/j.cca.2020.06.046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16980, KAKENHI-PROJECT-20H03579
[Presentation] 日当直に活かせるプラスワン技術2023
- Author(s)
  相原正宗
- Organizer
  日本医療検査科学会第55回大会
- Data Source
  KAKENHI-PROJECT-20H03579
[Presentation] 臨床分離Klebisella pneumoniaeにおける薬剤耐性遺伝子の増幅と耐性強化2023
- Author(s)
  相原正宗, 白濱早紀, 清祐麻紀子, 堀田多恵子
- Organizer
  第34回日本臨床微生物学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-20H03579
[Presentation] 血液培養検査ガイド第2版改定のポイント～臨床の現場で生かすには～同定・感受性検査の現状2023
- Author(s)
  相原正宗
- Organizer
  第34回日本臨床微生物学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-20H03579
[Presentation] 若手は集まろう！臨床から感染症リサーチに取り組む！臨床検査技師の立場から2023
- Author(s)
  相原正宗
- Organizer
  第93回日本感染症学会西日本地方会学術集会・第71回日本化学療法学会西日本支部総会合同学会
- Data Source
  KAKENHI-PROJECT-20H03579
[Presentation] 薬剤耐性（AMR）対策～ 2023年の提言を踏まえて～薬剤耐性菌検出を含めた検査体制2023
- Author(s)
  相原正宗
- Organizer
  第70回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03579
[Presentation] 肺炎桿菌の膜透過性低下に起因する耐性獲得と代謝関連遺伝子の代償的変化2022
- Author(s)
  相原正宗, 清祐麻紀子
- Organizer
  第92回日本感染症学会西日本地方会学術集会
- Data Source
  KAKENHI-PROJECT-20H03579
[Presentation] Polymyxin B nonapeptideを用いた腸内細菌目細菌における抗菌薬膜透過性低下の検出2022
- Author(s)
  柳澤由佳子, 相原正宗, 木部泰志, 清祐麻紀子, 堀田多恵子, 赤司　浩一
- Organizer
  日本医療検査科学会第54回大会
- Data Source
  KAKENHI-PROJECT-20H03579
[Presentation] 当院の人材育成の現状と工夫2021
- Author(s)
  相原正宗
- Organizer
  日本医療検査科学会第53回大会
- Data Source
  KAKENHI-PROJECT-20H03579
[Presentation] 同一患者内におけるKlebsiella pneumoniaeの薬剤高度耐性獲得過程の解析2021
- Author(s)
  相原正宗, 清祐麻紀子, 堀田多恵子, 康東天
- Organizer
  第68回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03579
[Presentation] 抗菌薬投与患者体内において段階的に薬剤耐性が強化されたKlebsiella pneumoniae ST628の解析2021
- Author(s)
  相原正宗, 後藤恭宏, 林哲也, 康東天
- Organizer
  九州微生物研究フォーラム2021
- Data Source
  KAKENHI-PROJECT-20H03579
[Presentation] 抗菌薬膜透過性低下によるカルバペネム耐性腸内細菌目細菌検出におけるpolymyxin B nonapeptideの有用性評価2021
- Author(s)
  相原正宗, 柳澤由佳子, 山下有加, 木部泰志, 清祐麻紀子, 堀田多恵子, 康東天
- Organizer
  日本医療検査科学会第53回大会
- Data Source
  KAKENHI-PROJECT-20H03579
[Presentation] 同一患者血液培養から経時的に検出されたKlebsiella pneumoniae 2株の全ゲノム比較解析2020
- Author(s)
  相原正宗　清祐麻紀子　康東天
- Organizer
  第30回福岡県医学検査学会
- Data Source
  KAKENHI-PROJECT-20H03579

1. Matsushima Yuichi (20571342)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 後藤恭宏 (20558358)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 瀬戸山大樹 (30550850)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 内海健 (80253798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. 康東天

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
6. 西岡光昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Aihara Masamune 相原 正宗

Research Projects

Research Products

Co-Researchers

Reserch for within-host bacterial evolution leading to increased antimicrobial resistancePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exploration of phenomena indicative of mitochondrial dysfunction and its applications

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Measurement of mitochondrial mRNA polyadenylation as a evaluation method for mitochondrial functionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Polymyxin B nonapeptide を用いたカルバペネム低感受性腸内細菌目細菌における抗菌薬膜透過性低下の検出2023

Author(s)

Journal Title

Data Source

[Journal Article] Mitochondrial Lon protease is a gatekeeper for proteins newly imported into the matrix2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Stepwise Evolution of a Klebsiella pneumoniae Clone within a Host Leading to Increased Multidrug Resistance2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Within-host evolution of a Klebsiella pneumoniae clone: selected mutations associated with the alteration of outer membrane protein expression conferred multidrug resistance.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] What is the best wavelength for the measurement of hemolysis index?2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] 日当直に活かせるプラスワン技術2023

Author(s)

Organizer

Data Source

[Presentation] 臨床分離Klebisella pneumoniaeにおける薬剤耐性遺伝子の増幅と耐性強化2023

Author(s)

Organizer

Data Source

[Presentation] 血液培養検査ガイド第2版改定のポイント～臨床の現場で生かすには～同定・感受性検査の現状2023

Author(s)

Organizer

Data Source

[Presentation] 若手は集まろう！臨床から感染症リサーチに取り組む！臨床検査技師の立場から2023

Author(s)

Organizer

Data Source

[Presentation] 薬剤耐性（AMR）対策～ 2023年の提言を踏まえて～ 薬剤耐性菌検出を含めた検査体制2023

Author(s)

Organizer

Data Source

[Presentation] 肺炎桿菌の膜透過性低下に起因する耐性獲得と代謝関連遺伝子の代償的変化2022

Author(s)

Organizer

Data Source

[Presentation] Polymyxin B nonapeptideを用いた腸内細菌目細菌における抗菌薬膜透過性低下の検出2022

Author(s)

Organizer

Data Source

[Presentation] 当院の人材育成の現状と工夫2021

Author(s)

Organizer

Data Source

[Presentation] 同一患者内におけるKlebsiella pneumoniaeの 薬剤高度耐性獲得過程の解析2021

Author(s)

Aihara Masamune 相原正宗

[Presentation] 薬剤耐性（AMR）対策～ 2023年の提言を踏まえて～薬剤耐性菌検出を含めた検査体制2023

[Presentation] 同一患者内におけるKlebsiella pneumoniaeの薬剤高度耐性獲得過程の解析2021

[Presentation] 抗菌薬投与患者体内において段階的に薬剤耐性が強化されたKlebsiella pneumoniae ST628の解析2021

[Presentation] 抗菌薬膜透過性低下によるカルバペネム耐性腸内細菌目細菌検出におけるpolymyxin B nonapeptideの有用性評価2021