Okada Masahiro 岡田匡央

Researcher Number	30749479
Affiliation (based on the past Project Information) *help	2021 – 2022: 国立研究開発法人理化学研究所, 生命医科学研究センター, 研究員 2017 – 2018: 慶應義塾大学, 医学部(信濃町), 特任助教
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Biological pharmacy
Keywords	Principal Investigator TCR / Multiple Myeloma / Neoantigens / multiple myeloma / single cell / TCR-T / neoantigens / フコース / コアフコシル化 / 糖鎖 … More / 腫瘍免疫 / Fut8 / PD-1 / tumor immunity / core fucose / fut8 / pd-1 Less

Donor derived neoantigens specific TCR-T therapy against multiple myeloma in preclinical modelPrincipal Investigator
- Principal Investigator
  
  Okada Masahiro
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Institute of Physical and Chemical Research
Blocking core fucosylation of PD-1 reduces cell-surface expression and promotes anti-tumor immune responses of T CellsPrincipal Investigator
- Principal Investigator
  
  Okada Masahiro
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Keio University

All 2022 2021 2017

All Journal Article Presentation

[Journal Article] ゲルゾリンと腫瘍免疫2022
- Author(s)
  岡田匡央、伊豫田智典、清水佳奈子、藤井眞一郎
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 77(6) Pages: 764-770
- Data Source
  KAKENHI-PROJECT-21K16278
[Journal Article] Identification of Neoantigens in Cancer Cells as Targets for Immunotherapy.2022
- Author(s)
  Okada M, Shimizu K, Fujii S.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 5 Pages: 2594-2594
- DOI
  10.3390/ijms23052594
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07653, KAKENHI-PROJECT-21K16278
[Journal Article] Identification of TCR repertoires in functionally competent cytotoxic T cells cross-reactive to SARS-CoV-22021
- Author(s)
  Shimizu Kanako、Iyoda Tomonori、Sanpei An、Nakazato Hiroshi、Okada Masahiro、Ueda Shogo、Kato-Murayama Miyuki、Murayama Kazutaka、Shirouzu Mikako、Harada Naoko、Hidaka Michihiro、Fujii Shin-ichiro
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1
- DOI
  10.1038/s42003-021-02885-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16278
[Journal Article] Blockage of Core Fucosylation Reduces Cell-Surface Expression of PD-1 and Promotes Anti-tumor Immune Responses of T Cells.2017
- Author(s)
  Okada M, Chikuma S et al.
- Journal Title
  
  Cell Reports
  
  Volume: 20 Issue: 5 Pages: 1017-1028
- DOI
  10.1016/j.celrep.2017.07.027
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08847, KAKENHI-PROJECT-17K15451, KAKENHI-INTERNATIONAL-16K21731, KAKENHI-ORGANIZER-16H06495, KAKENHI-PLANNED-16H06501, KAKENHI-PUBLICLY-17H05801, KAKENHI-PROJECT-17H03600, KAKENHI-PROJECT-17H07088, KAKENHI-PROJECT-15J07566, KAKENHI-PROJECT-15K19128
[Presentation] Chromatin remodeling complex curtails the efficacy of PD-1 blockade in anti-cancer drug-resistant tumor.2022
- Author(s)
  Masahiro Okada, Kanako Shimizu and Shin-ichiro Fujii
- Organizer
  第51回　日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21K16278
[Presentation] 腫瘍PD-L1の発現はネオ抗原反応性を決定する2021
- Author(s)
  岡田　匡央、清水　佳奈子、伊豫田　智典、藤井　眞一郎
- Organizer
  第13回　日本血液疾患免疫療法学会学術集会
- Data Source
  KAKENHI-PROJECT-21K16278

1. FUJII Shinーichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 竹馬俊介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 清水佳奈子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Okada Masahiro 岡田 匡央

Research Projects

Research Products

Co-Researchers

Donor derived neoantigens specific TCR-T therapy against multiple myeloma in preclinical modelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Blocking core fucosylation of PD-1 reduces cell-surface expression and promotes anti-tumor immune responses of T CellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] ゲルゾリンと腫瘍免疫2022

Author(s)

Journal Title

Data Source

[Journal Article] Identification of Neoantigens in Cancer Cells as Targets for Immunotherapy.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of TCR repertoires in functionally competent cytotoxic T cells cross-reactive to SARS-CoV-22021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Blockage of Core Fucosylation Reduces Cell-Surface Expression of PD-1 and Promotes Anti-tumor Immune Responses of T Cells.2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] Chromatin remodeling complex curtails the efficacy of PD-1 blockade in anti-cancer drug-resistant tumor.2022

Author(s)

Organizer

Data Source

[Presentation] 腫瘍PD-L1の発現はネオ抗原反応性を決定する2021

Author(s)

Organizer

Data Source

Okada Masahiro 岡田匡央