Horinouchi Tomoko 堀之内智子

Researcher Number	30754593
Other IDs
Affiliation (Current)	2025: 神戸大学, 医学部附属病院, 講師
Affiliation (based on the past Project Information) *help	2023 – 2024: 神戸大学, 医学部附属病院, 講師 2020 – 2023: 神戸大学, 医学研究科, 助教 2019: 神戸大学, 医学研究科, 特命助教 2018: 神戸大学, 医学研究科, 医学研究員
Review Section/Research Field	Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Basic Section 53040:Nephrology-related / Medium-sized Section 53:Organ-based internal medicine and related fields / Basic Section 52050:Embryonic medicine and pediatrics-related
Keywords	Principal Investigator 小児特発性ネフローゼ症候群 / 自己抗体 / 腎病理組織 / RNA解析 / ウイルス感染 / HLA / NPHS1 / ネフリン / HLA class II / ステロイド感受性ネフローゼ症候群 … More / 小児ネフローゼ症候群 / Whole-exome sequencing / プロテインアクティブアレイ / 網羅的自己抗体検索 / 単一遺伝子異常 / 疾患関連自己抗体 / genotype-phenotype / 単一遺伝子病 / 疾患感受性遺伝子 … More Except Principal Investigator 小児ネフローゼ症候群 / ネフローゼ症候群 / 抗ネフリン抗体 / ネフリン / 疾患感受性遺伝子 / レニン・アンギオテンシン・アルドステロン系 / 早産、低出生体重児 / リツキシマブ / GWASメタ解析 / 腎臓オルガノイド / iPS細胞 / 器官システム内科学 / 腎臓学 / フィンランド型先天性ネフローゼ症候群 / ゲノムワイド関連解析 / ステロイド感受性ネフローゼ症候群 Less

Elucidation of the mechanism of rituximab-induced long-term remission in childhood nephrotic syndrome
- Principal Investigator
  
  飯島一誠
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Kobe University
レニンアンギオテンシン系に着目した早産、低出生体重児の腎障害進展機序の解明研究
- Principal Investigator
  
  石森真吾
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Aijinkai Healthcare Corporation Takatsuki General Hospital Clinical Research Center
RNA解析を用いた小児腎疾患と感染症の関連解明研究Principal Investigator
- Principal Investigator
  
  堀之内智子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kobe University
Joint international Research Project for International GWAS Meta-Analysis and Anti-Nephrin Autoantibodies in Childhood Nephrotic Syndrome
- Principal Investigator
  
  Iijima Kazumoto
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Kobe University
Study to clarify the pathophysiology of childhood nephrotic syndrome and HLA class IIPrincipal Investigator
- Principal Investigator
  
  Horinouchi Tomoko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kobe University
Clarification of the pathogenesis of childhood nephrotic syndrome using iPS cell-derived kidney organoids
- Principal Investigator
  
  Iijima Kazumoto
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Kobe University
Elucidation of pathogenesis of steroid-sensitive nephrotic syndromePrincipal Investigator
- Principal Investigator
  
  Horinouchi Tomoko
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kobe University
Joint International Research for identification of disease-susceptible genes and drug-sensitive genes in childhood nephrotic syndrome
- Principal Investigator
  
  IIJIMA KAZUMOTO
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Kobe University

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation Book

[Book] 6.【～エキスパートの経験に学ぶ～小児科Decision Making】腎・泌尿器に関する病態　蛋白尿(解説/特集)2021
- Author(s)
  堀之内智子, 野津寛大, 飯島一誠
- Total Pages
  3
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-20K16892
[Book] 3.【腎疾患-エキスパートへの質問で学ぶ診療のキホンと最新情報】遺伝性腎疾患　遺伝学的検査をすべき成人の遺伝性腎疾患について教えてください(解説/特集)2021
- Author(s)
  堀之内智子, 野津寛大
- Total Pages
  3
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-20K16892
[Journal Article] Role of Iron in Children With Immunoglobulin A Nephropathy and Macrohematuria-Induced Acute Kidney Injury2024
- Author(s)
  Ishimori Shingo、Horinouchi Tomoko、Yamamura Tomohiko、Fujimura Junya、Kamiyoshi Naohiro、Kaito Hiroshi、Tanaka Yuriko、Matsukura Hiroyoshi、Shimabukuro Wataru、Shima Yuko、Kawaguchi Azusa、Araki Yoshinori、Nakanishi Koichi、Hara Shigeo、Nozu Kandai
- Journal Title
  
  Kidney International Reports
  
  Volume: 未 Issue: 6 Pages: 1664-1673
- DOI
  10.1016/j.ekir.2024.03.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07242
[Journal Article] 【腎臓学この1年の進歩】ネフリンとネフローゼ症候群2024
- Author(s)
  飯島一誠, 堀之内智子, 長野智那, 野津寛大
- Journal Title
  
  日本腎臓学会誌
  
  Volume: 66巻 Pages: 303-309
- Data Source
  KAKENHI-PROJECT-21KK0147
[Journal Article] A multicenter retrospective study of calcineurin inhibitors in nephrotic syndrome secondary to podocyte gene variants2023
- Author(s)
  Malakasioti G, Iancu D, Milovanova A, Tsygin A, Horinouchi T, Nagano C, Nozu K, Kamei K, Fujinaga S, Iijima K, et al. ; CNI in Monogenic SRNS Study Investigators
- Journal Title
  
  Kidney International
  
  Volume: 103 Issue: 5 Pages: 962-972
- DOI
  10.1016/j.kint.2023.02.022
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21KK0147, KAKENHI-PROJECT-20H03698
[Journal Article] Anti-nephrin antibodies in steroid-sensitive nephrotic syndrome in Japanese children2023
- Author(s)
  Horinouchi Tomoko、Nagano China、Watts Andrew J. B.
- Journal Title
  
  Pediatric Nephrology
  
  Volume: 39 Issue: 1 Pages: 337-337
- DOI
  10.1007/s00467-023-06107-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21KK0147, KAKENHI-PROJECT-23K27617
[Journal Article] Rituximab in combination with cyclosporine and steroid pulse therapy for childhood-onset multidrug-resistant nephrotic syndrome: a multicenter single-arm clinical trial (JSKDC11 trial)2023
- Author(s)
  Nozu Kandai、Sako Mayumi、Tanaka Seiji、Kano Yuji、Ohwada Yoko、Morohashi Tamaki、Hamada Riku、Ohtsuka Yasufumi、Oka Masafumi、Kamei Koichi、Inaba Aya、Ito Shuichi、Sakai Tomoyuki、Kaito Hiroshi、Shima Yuko et al.
- Journal Title
  
  Clinical and Experimental Nephrology
  
  Volume: 28 Issue: 4 Pages: 337-348
- DOI
  10.1007/s10157-023-02431-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07300, KAKENHI-PROJECT-21KK0147, KAKENHI-PROJECT-23K27617
[Journal Article] Steroid resistant nephrotic syndrome with collapsing focal segmental glomerulosclerosis in a 12-year-old Japanese female after SARS-CoV-2 vaccination2023
- Author(s)
  Horinouchi Tomoko、Ueda Chika、Kitakado Hideaki、Yoshikawa Norishige、Nozu Kandai
- Journal Title
  
  Journal of Nephrology
  
  Volume: online ahead of print Issue: 5 Pages: 1-4
- DOI
  10.1007/s40620-023-01577-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K16892
[Journal Article] Multi-population genome-wide association study implicates immune and non-immune factors in pediatric steroid-sensitive nephrotic syndrome2023
- Author(s)
  Barry A, McNulty MT, Jia X, Nagano C, Horinouchi T, Nozu K, Tokunaga K, Ronco P, Iijima K, Sampson MG, et al.
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 2481-2481
- DOI
  10.1038/s41467-023-37985-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21KK0147, KAKENHI-PROJECT-23K27617
[Journal Article] 【遺伝を考える】(II章)遺伝学的診断　個別診療分野における遺伝学的診断の進歩　腎・泌尿器領域2023
- Author(s)
  飯島一誠, 堀之内智子, 野津寛大
- Journal Title
  
  日本医師会雑誌
  
  Volume: 152巻特別1
- Data Source
  KAKENHI-PROJECT-21KK0147
[Journal Article] 【遺伝を考える】(II章)遺伝学的診断　個別診療分野における遺伝学的診断の進歩　腎・泌尿器領域2023
- Author(s)
  飯島一誠, 堀之内智子, 野津寛大
- Journal Title
  
  日本医師会雑誌
  
  Volume: 152巻特別1
- Data Source
  KAKENHI-PROJECT-23K27617
[Journal Article] An updated view of the pathogenesis of steroid-sensitive nephrotic syndrome2022
- Author(s)
  Horinouchi Tomoko、Nozu Kandai、Iijima Kazumoto
- Journal Title
  
  Pediatric Nephrology
  
  Volume: - Issue: 9 Pages: 1957-1965
- DOI
  10.1007/s00467-021-05401-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03698, KAKENHI-PROJECT-20K16892, KAKENHI-PROJECT-21KK0147
[Journal Article] Clinical, Pathological, and Genetic Characteristics in Patients with Focal Segmental Glomerulosclerosis2022
- Author(s)
  Nagano C, Hara S, Yoshikawa N, Takeda A, Gotoh Y, Hamada R, Matsuoka K, Yamamoto M, Fujinaga S, Sakuraya K, Kamei K, Hamasaki Y, Oguchi H, Araki Y, Ogawa Y, Okamoto T, Ito S, Tanaka S, Kaito H, Aoto Y, Ishiko S, Rossanti R, Sakakibara N, Horinouchi T, Yamamura T, Nagase H, Iijima K, Nozu K
- Journal Title
  
  Kidney360
  
  Volume: 3 Issue: 8 Pages: 1384-1393
- DOI
  10.34067/kid.0000812022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21KK0147, KAKENHI-PROJECT-20H03698
[Journal Article] Cite Share Detecting MUC1 Variants in Patients Clinicopathologically Diagnosed With Having Autosomal Dominant Tubulointerstitial Kidney Disease2022
- Author(s)
  Okada E, Morisada N, Horinouchi T, Fujii H, Tsuji T, Miura M, Katori H, Kitagawa M, Morozumi K, Toriyama T, Nakamura Y, Nishikomori R, Nagai S, Kondo A, Aoto Y, Ishiko S, Rossanti R, Sakakibara N, Nagano C, Yamamura T, Ishimori S, Usui J, Yamagata K, Iijima K, Imasawa T, Nozu K.
- Journal Title
  
  Kidney Int Rep.
  
  Volume: 7 Issue: 4 Pages: 857-866
- DOI
  10.1016/j.ekir.2021.12.037
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16892, KAKENHI-PROJECT-22K08351, KAKENHI-PROJECT-23K21401
[Journal Article] Is influenza vaccination associated with nephrotic syndrome relapse in children? A multicenter prospective study2022
- Author(s)
  Ishimori S, Horinouchi T, Fujimura J, Yamamura T, Matsunoshita N, Kamiyoshi N, Sato M, Ogura M, Kamei K, Ishikura K, Iijima K, Nozu K
- Journal Title
  
  Pediatric Nephrology
  
  Volume: Nov 30 Issue: 7 Pages: 2107-2116
- DOI
  10.1007/s00467-022-05783-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21KK0147, KAKENHI-PROJECT-20H03698
[Journal Article] FAT1 biallelic truncating mutation causes a non-syndromic proteinuria in a child.2021
- Author(s)
  Rossanti R, Watanabe T, Nagano C, Hara S, Horinouchi T, Yamamura T, Sakakibara N, Ninchoji T, Iijima K, Nozu K.
- Journal Title
  
  CEN Case Reports
  
  Volume: 10(1) Issue: 1 Pages: 100-105
- DOI
  10.1007/s13730-020-00529-y
- Open Access
- Data Source
  KAKENHI-PROJECT-18KK0244
[Journal Article] Clear Evidence of <i>LAMA5</i> Gene Biallelic Truncating Variants Causing Infantile Nephrotic Syndrome2021
- Author(s)
  Taniguchi Yukimasa、Nagano China、Sekiguchi Kiyotoshi、Tashiro Atsushi、Sugawara Noriko、Sakaguchi Haruhide、Umeda Chisato、Aoto Yuya、Ishiko Shinya、Rossanti Rini、Sakakibara Nana、Horinouchi Tomoko、Yamamura Tomohiko、Kondo Atsushi、Nagai Sadayuki、Nagase Hiroaki、Iijima Kazumoto、Miner Jeffrey H.、Nozu Kandai
- Journal Title
  
  Kidney360
  
  Volume: 2 Issue: 12 Pages: 1968-1978
- DOI
  10.34067/kid.0004952021
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08726, KAKENHI-PROJECT-20K16892
[Journal Article] An extremely mild clinical course in a case with LAMB2-associated nephritis diagnosed with next-generation sequencing.2021
- Author(s)
  Sakuraya K, Nozu K, Murakami H, Nagano C, Horinouchi T, Fujinaga S, Iijima K, Ohtomo Y.
- Journal Title
  
  CEN Case Reports
  
  Volume: - Issue: 3 Pages: 359-363
- DOI
  10.1007/s13730-021-00574-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KK0244, KAKENHI-PROJECT-19K08726
[Journal Article] Glomerular galactose-deficient IgA1 expression analysis in pediatric patients with glomerular diseases2020
- Author(s)
  Ishiko Shinya、Horinouchi Tomoko、Fujimaru Rika、Shima Yuko et al.
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1
- DOI
  10.1038/s41598-020-71101-y
- NAID
  120006954852
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07799, KAKENHI-PROJECT-20K16892
[Journal Article] Common risk variants in NPHS1 and TNFSF15 are associated with childhood steroid-sensitive nephrotic syndrome2020
- Author(s)
  Jia Xiaoyuan、Yamamura Tomohiko、et al.
- Journal Title
  
  Kidney International
  
  Volume: 98 Issue: 5 Pages: 1308-1322
- DOI
  10.1016/j.kint.2020.05.029
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07799, KAKENHI-PROJECT-19K08726, KAKENHI-PROJECT-20K08370, KAKENHI-PROJECT-20K16892, KAKENHI-PROJECT-18KK0244, KAKENHI-PROJECT-20H03698
[Journal Article] Comprehensive genetic diagnosis of Japanese patients with severe proteinuria.2020
- Author(s)
  Nagano C, Yamamura T, Horinouchi T, Aoto Y, Ishiko S, Sakakibara N, Shima Y, Nakanishi K, Nagase H, Iijima K, Nozu K.
- Journal Title
  
  Sci Rep.
  
  Volume: 10(1) Issue: 1 Pages: 428-437
- DOI
  10.1038/s41598-019-57149-5
- NAID
  120006884200
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07799, KAKENHI-PROJECT-19K08726, KAKENHI-PROJECT-18KK0244, KAKENHI-PROJECT-18K15713
[Journal Article] Male CDPX2 patient with EBP mosaicism and asymmetrically lateralized skin lesions with strict midline demarcation2019
- Author(s)
  Horinouchi Tomoko、Morisada Naoya、Uemura Hiroyasu、Kobayashi Daisuke、Nozu Kandai、Okamoto Nobuhiko、Iijima Kazumoto
- Journal Title
  
  American Journal of Medical Genetics Part A
  
  Volume: 179 Issue: 7 Pages: 1315-1318
- DOI
  10.1002/ajmg.a.61159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08243, KAKENHI-PROJECT-18K15712
[Journal Article] Determination of the pathogenicity of known COL4A5 intronic variants by in vitro splicing assay.2019
- Author(s)
  Horinouchi T, Nozu K, Yamamura T, Minamikawa S, Nagano C, Sakakibara N, Nakanishi K, Shima Y, Morisada N, Ishiko S, Aoto Y, Nagase H, Takeda H, Rossanti R, Kaito H, Matsuo M, Iijima K.
- Journal Title
  
  Sci Rep.
  
  Volume: 9(1) Issue: 1 Pages: 12696-12696
- DOI
  10.1038/s41598-019-48990-9
- NAID
  120006825910
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07799, KAKENHI-PROJECT-18K08243, KAKENHI-PROJECT-19K08726, KAKENHI-PROJECT-17H04189, KAKENHI-PROJECT-18K15712
[Journal Article] Molecular assay for an intronic variant in NUP93 that causes steroid resistant nephrotic syndrome2019
- Author(s)
  Rossanti Rini、Shono Akemi、Miura Kenichiro、Hattori Motoshi、Yamamura Tomohiko、Nakanishi Keita、Minamikawa Shogo、Fujimura Junya、Horinouchi Tomoko、Nagano China、Sakakibara Nana、Kaito Hiroshi、Nagase Hiroaki、Morisada Naoya、Asanuma Katsuhiko、Matsuo Masafumi、Nozu Kandai、Iijima Kazumoto
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 64 Issue: 7 Pages: 673-679
- DOI
  10.1038/s10038-019-0606-4
- NAID
  120006653286
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08243, KAKENHI-PROJECT-19K09921, KAKENHI-PROJECT-18KK0244, KAKENHI-PROJECT-18K15712, KAKENHI-PROJECT-18H02823
[Journal Article] Study protocol: mycophenolate mofetil as maintenance therapy after rituximab treatment for childhood-onset, complicated, frequently-relapsing nephrotic syndrome or steroid-dependent nephrotic syndrome: a multicenter double-blind, randomized, placebo-controlled trial (JSKDC07)2018
- Author(s)
  Horinouchi Tomoko、Sako Mayumi、Nakanishi Koichi、Ishikura Kenji、Ito Shuichi、Nakamura Hidefumi、Oba Mari Saito、Nozu Kandai、Iijima Kazumoto
- Journal Title
  
  BMC Nephrology
  
  Volume: 19 Issue: 1 Pages: 302-302
- DOI
  10.1186/s12882-018-1099-7
- NAID
  120006539303
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KK0244
[Journal Article] The utility of urinary CD80 as a diagnostic marker in patients with renal diseases2018
- Author(s)
  Minamikawa Shogo、Nozu Kandai、Maeta Shingo、Yamamura Tomohiko、Nakanishi Keita、Fujimura Junya、Horinouchi Tomoko、Nagano China、Sakakibara Nana、Nagase Hiroaki、Shima Hideaki、Noda Kenta、Ninchoji Takeshi、Kaito Hiroshi、Iijima Kazumoto
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 17322-17322
- DOI
  10.1038/s41598-018-35798-2
- NAID
  120006543320
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KK0244
[Journal Article] Pair analysis and custom array CGH can detect a small copy number variation in COQ6 gene2018
- Author(s)
  Nakanishi Keita、Okamoto Takayuki、Nozu Kandai、Hara Shigeo、Sato Yasuyuki、Hayashi Asako、Takahashi Toshiyuki、Nagano China、Sakakibara Nana、Horinouchi Tomoko、Fujimura Junya、Minamikawa Shogo、Yamamura Tomohiko、Rossanti Rini、Nagase Hiroaki、Kaito Hiroshi、Ariga Tadashi、Iijima Kazumoto
- Journal Title
  
  Clinical and Experimental Nephrology
  
  Volume: 23 Issue: 5 Pages: 669-675
- DOI
  10.1007/s10157-018-1682-z
- NAID
  120006644119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18KK0244, KAKENHI-PROJECT-17K16262, KAKENHI-PROJECT-18K15712
[Journal Article] ステロイド感受性ネフローゼ症候群とゲノムワイド関連解析2018
- Author(s)
  飯島一誠, 堀之内智子, 野津寛大
- Journal Title
  
  【ネフローゼ症候群-MCNS/FSGSの最新知見】病因、病態、病理学
  
  Volume: 85巻6号 Pages: 777-781
- Data Source
  KAKENHI-PROJECT-18KK0244
[Journal Article] Strong Association of the HLA-DR/DQ Locus with Childhood Steroid-Sensitive Nephrotic Syndrome in the Japanese Population.2018
- Author(s)
  Jia X, Horinouchi T, Hitomi Y, Shono A, Khor SS, Omae Y, Kojima K, Kawai Y, Nagasaki M, Kaku Y, Okamoto T, Ohwada Y, Ohta K, Okuda Y, Fujimaru R, Hatae K, Kumagai N, Sawanobori E, Nakazato H, Ohtsuka Y, Nakanishi K, Shima Y, Tanaka R, Ashida A, Kamei K, Ishikura K, Nozu K, Tokunaga K, Iijima K
- Journal Title
  
  J Am Soc Nephrol.
  
  Volume: 29 Issue: 8 Pages: 2189-2199
- DOI
  10.1681/asn.2017080859
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07799, KAKENHI-PROJECT-18KK0244, KAKENHI-PLANNED-18H05511, KAKENHI-PROJECT-15K09694, KAKENHI-PROJECT-16K10066
[Presentation] 早産や低出生体重児の潜在的レニン・アンギオテンシン・アルドステロン系亢進の存在に関する検討2024
- Author(s)
  石森真吾、北角英晶、近藤淳、藤村順也、堀之内智子、野津寛大
- Organizer
  第59回　日本小児腎臓病学会学術集会
- Data Source
  KAKENHI-PROJECT-23K07242
[Presentation] 早産や低出生体重児の潜在的レニン・アンギオテンシン・アルドステロン（RAAS）系亢進の存在に関する検討2024
- Author(s)
  石森真吾、北角英晶、近藤淳、藤村順也、堀之内智子、野津寛大
- Organizer
  第67回　日本腎臓学会学術集会
- Data Source
  KAKENHI-PROJECT-23K07242
[Presentation] Common Variants in Mendelian Disease Genes as Risk Factors for CKD2023
- Author(s)
  Tomoko Horinouchi
- Organizer
  American Society of Nephrology Kidney week 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07266
[Presentation] Onset mechanisms and prognosis in pediatric patients with IgA nephropathy accompanied by macrohematuria-induced acute kidney injury: a multicenter study2023
- Author(s)
  Shingo Ishimori, Tomoko Horinouchi, Tomohiko Yamamura, Junya Fujimura, Naohiro Kamiyoshi, Hiroshi Kaito, Yuriko Tanaka, Hiroki Matsukura, Wataru Shimabukuro, Yuko Shima, Azusa Kawaguchi, Yoshinori Araki, Koichi Nakanishi, Shigeo Hara, Kandai Nozu
- Organizer
  15th Asian Congress of Pediatric Nephrology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07242
[Presentation] Twelve-year-old girl with steroid resistant nephrotic syndrome with collapsing focal segmental glomerulosclerosis after COVID-19 vaccination2022
- Author(s)
  Masuda C, Horinouchi T, Kitakado H et al.
- Organizer
  ASN kidney week 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16892
[Presentation] 15.Treatment with antisense-oligonucleotide or splicing regulating proteins for X-linked Alport syndrome cases with deep intronic variants2021
- Author(s)
  Horinouchi Tomoko, Yamamura Tomohiko, Nagai Sadayuki, Kondo Atsushi, Aoto Yuya, Okada Eri, Rossanti Rini, Sakakibara Nana, Nagano China, Ninchoji Takeshi, Iijima Kazumoto, Nozu Kandai
- Organizer
  第64回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-20K16892
[Presentation] Alport syndrome UP TO DATE 2 Genetics and novel treatment Tomoko2021
- Author(s)
  HORINOUCHI, Kandai NOZU, Tomohiko YAMAMURA and Kazumoto IIJIMA
- Organizer
  The 18thJAPAN-KOREA-CHINA Pediatric Nephrology Seminar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16892
[Presentation] 16.小児から成人へのシームレスなネフローゼ診療　単一遺伝子異常と小児および成人におけるネフローゼ症候群2021
- Author(s)
  堀之内智子, 野津寛大, 長野智那, 飯島一誠
- Organizer
  第64回日本腎臓学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K16892
[Presentation] Novel nephrin protein/HLA classII complexes: A new mechanism of steroid sensitive nephrotic syndrome2020
- Author(s)
  Tomoko Horinouchi, China Nagano, Tomohiko Yamamura, Masako Kohyama, Kandai Nozu, Kazumoto Iijima, Hisashi Arase
- Organizer
  第55回日本小児腎臓病学会学術集会
- Data Source
  KAKENHI-PROJECT-20K16892
[Presentation] Novel nephrin protein/HLA class II complexes: A new mechanism of steroid sensitive nephrotic syndrome2020
- Author(s)
  Tomoko Horinouchi, Sadayuki Nagai, Atsushi Kondo, Yuya Aoto, Shinya Ishiko, Rini Rossanti, Nana Sakakibara, China Nagano, Tomohiko Yamamura, Takeshi Ninchoji, Kandai Nozu, Kazumoto Iijima
- Organizer
  American Society of Nephrology, Kidney week 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16892
[Presentation] NPHS1は小児ステロイド感受性ネフローゼ症候群の疾患感受性遺伝子である2019
- Author(s)
  山村智彦、長野智那、堀之内智子、野津寛大、飯島一誠
- Organizer
  第62回日本腎臓学会学術集会
- Data Source
  KAKENHI-PROJECT-18KK0244
[Presentation] 常染色体劣性Alport症候群39家系46人の臨床遺伝学的検討2019
- Author(s)
  堀之内智子、野津寛大、榊原菜々、長野智那、南川将吾、山村智彦、飯島一誠
- Organizer
  第62回日本腎臓学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15712
[Presentation] Common risk variants in NPHS1 and TNFSF15 are associated with childhood steroid-sensitive nephrotic syndrome2019
- Author(s)
  Tomoko Horinouchi, Tomohiko Yamamura, Rasheed A. Gbadegesin, Matthew G. Sampson, China Nagano, Kandai Nozu, Kenji Ishikura, Pierre M. Ronco, Hae Il Cheong, Kazumoto Iijima
- Organizer
  American Society of Nephrology Kidney week 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0244
[Presentation] 多嚢胞性異形成腎20症例の臨床的検討2019
- Author(s)
  堀之内智子、貝藤裕史、稲熊洋祐、森貞直哉、飯島一誠、田中亮二郎
- Organizer
  第122回日本小児科学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15712
[Presentation] Common risk variants in NPHS1 and TNFSF15 are associated with childhood steroid-sensitive nephrotic syndrome2019
- Author(s)
  Tomoko Horinouchi, Tomohiko Yamamura, Rasheed A. Gbadegesin, Matthew G. Sampson, China Nagano, Kandai Nozu, Kenji Ishikura, Pierre M. Ronco, Hae Il Cheong, Kazumoto Iijima
- Organizer
  American Society of Nephrology Kidney week 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15712
[Presentation] 常染色体劣性Alport症候群39家系46人の臨床遺伝学的検討2019
- Author(s)
  堀之内智子、野津寛大、石河慎也、青砥悠哉、榊原菜々、長野智那、南川将吾、山村智彦、貝藤裕史、森貞直哉、飯島一誠
- Organizer
  第54回日本小児腎臓病学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15712
[Presentation] 遺伝性腎疾患に対するプレシジョンメデイスン　小児ステロイド感受性ネフローゼ症候群の疾患感受性遺伝子2019
- Author(s)
  飯島一誠、 Jia Xiaoyuan,、山村智彦、人見祐基、長野智那、堀之内智子、野津寛大、徳永勝士
- Organizer
  第54回日本小児腎臓病学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0244
[Presentation] ゲノムワイド関連解析による小児特発性ネフローゼ症候群のrisk haplotype同定2018
- Author(s)
  堀之内智子
- Organizer
  第53回日本小児腎臓病学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15712
[Presentation] ゲノムワイド関連解析による小児特発性ネフローゼ症候群のrisk haplotype同定2018
- Author(s)
  堀之内　智子、野津　寛大、石倉　健司、飯島　一誠
- Organizer
  第61回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-18KK0244
[Presentation] ゲノムワイド関連解析による小児特発性ネフローゼ症候群のrisk haplotype同定2018
- Author(s)
  堀之内智子
- Organizer
  第61回日本腎臓学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15712
[Presentation] ゲノムワイド関連解析による小児特発性ネフローゼ症候群のrisk haplotype同定2018
- Author(s)
  堀之内　智子、Xiaoyuan Jia、人見　祐基、石倉　健司、亀井　宏一、濱田　陸、郭　義胤、藤丸　季可、岡本　孝之、大和田　葉子、田中　亮二郎、後藤　芳充、貝籐　裕史、野津　寛大、徳永　勝士、飯島　一誠
- Organizer
  第53回小児腎臓病学会学術集会
- Data Source
  KAKENHI-PROJECT-18KK0244

1. 野津寛大 (70362796)

# of Collaborated Projects: 5 results

# of Collaborated Products: 24 results
2. IIJIMA KAZUMOTO (00240854)

# of Collaborated Projects: 4 results

# of Collaborated Products: 19 results
3. 長野智那 (60814316)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
4. 人見祐基 (10525819)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 高里実 (40788676)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 賈暁媛 (20914328)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 中山真紀子 (80469999)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 宮西正憲 (80542969)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 石森真吾 (30465950)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. SHIMA Yuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
11. NAKANISHI Koichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
12. MORISADA Naoya

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Horinouchi Tomoko 堀之内 智子

Research Projects

Research Products

Co-Researchers

Elucidation of the mechanism of rituximab-induced long-term remission in childhood nephrotic syndrome

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レニンアンギオテンシン系に着目した早産、低出生体重児の腎障害進展機序の解明研究

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RNA解析を用いた小児腎疾患と感染症の関連解明研究Principal Investigator

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Joint international Research Project for International GWAS Meta-Analysis and Anti-Nephrin Autoantibodies in Childhood Nephrotic Syndrome

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Study to clarify the pathophysiology of childhood nephrotic syndrome and HLA class IIPrincipal Investigator

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Clarification of the pathogenesis of childhood nephrotic syndrome using iPS cell-derived kidney organoids

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Elucidation of pathogenesis of steroid-sensitive nephrotic syndromePrincipal Investigator

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Joint International Research for identification of disease-susceptible genes and drug-sensitive genes in childhood nephrotic syndrome

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[Book] 6.【～エキスパートの経験に学ぶ～小児科Decision Making】腎・泌尿器に関する病態 蛋白尿(解説/特集)2021

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[Book] 3.【腎疾患-エキスパートへの質問で学ぶ診療のキホンと最新情報】遺伝性腎疾患 遺伝学的検査をすべき成人の遺伝性腎疾患について教えてください(解説/特集)2021

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[Journal Article] Role of Iron in Children With Immunoglobulin A Nephropathy and Macrohematuria-Induced Acute Kidney Injury2024

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[Journal Article] 【腎臓学この1年の進歩】ネフリンとネフローゼ症候群2024

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[Journal Article] A multicenter retrospective study of calcineurin inhibitors in nephrotic syndrome secondary to podocyte gene variants2023

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[Journal Article] Anti-nephrin antibodies in steroid-sensitive nephrotic syndrome in Japanese children2023

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Horinouchi Tomoko 堀之内智子

[Book] 6.【～エキスパートの経験に学ぶ～小児科Decision Making】腎・泌尿器に関する病態　蛋白尿(解説/特集)2021

[Book] 3.【腎疾患-エキスパートへの質問で学ぶ診療のキホンと最新情報】遺伝性腎疾患　遺伝学的検査をすべき成人の遺伝性腎疾患について教えてください(解説/特集)2021

[Journal Article] 【遺伝を考える】(II章)遺伝学的診断　個別診療分野における遺伝学的診断の進歩　腎・泌尿器領域2023

[Journal Article] 【遺伝を考える】(II章)遺伝学的診断　個別診療分野における遺伝学的診断の進歩　腎・泌尿器領域2023