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Yoshioka Hiroki  吉岡 弘毅

… Alternative Names

YOSHIOKA HIROKI  吉岡 弘毅

吉岡 弘毅  ヨシオカ ヒロキ

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Researcher Number 30756606
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-0977-434X
Affiliation (Current) 2025: 北里大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help 2022 – 2025: 岐阜医療科学大学, 薬学部, 講師
2023: 岐阜医療科学大学, 薬学部薬学科, 講師
2022: 金城学院大学, 薬学部, 助教
2020 – 2022: 岐阜医療科学大学, 保健科学部, 研究員
2017 – 2018: 金城学院大学, 薬学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 58020:Hygiene and public health-related: including laboratory approach / Basic Section 47060:Clinical pharmacy-related
Except Principal Investigator
Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Basic Section 52050:Embryonic medicine and pediatrics-related / Basic Section 57060:Surgical dentistry-related / Basic Section 58010:Medical management and medical sociology-related / Risk sciences of radiation and chemicals
Keywords
Principal Investigator
シスプラチン / 時間毒性 / 時間薬理
Except Principal Investigator
糖鎖代謝 / N-glycan / 遊離N-glycan / ゴルジ体ストレス / 時空間解析 / 代謝フラックス / in vivoイメージング … More / 胚発生 / ゲノム毒性 / 精子 / 小児がんサバイバー / 歯髄幹細胞 / シェーグレン症候群 / ヘルパーT細胞 / 抗炎症作用 / エクソソーム / iPS細胞 / シフトワーカー / 生体リズム / 糖尿病患者 / 交替勤務者 / 血糖トレンド値 / 血糖管理 / 概日リズム / 血糖降下剤 / 糖尿病 / 交替制勤務 / 衛生 / 肝障害 / 酸化チタン / トキシコロジー / 精巣毒性 / 二酸化チタンナノ粒子 / IVF法 / チタンナノ粒子 / 精子運動能 / 精巣機能 / ナノ粒子 / 二酸化チタン / 2-フルオロフコース / 1-デオキシマンノジリマイシン / キフネシン / スワインソニン / 遊離オリゴ糖 / 複合糖質 / ケミカルグライコミクス / ブレフェルディンA / 阻害剤 / グライコミクス / 細胞内動態 / 定性・定量解析 / パウチマンノース型 / モノアンテナ型 / ハイブリッド型 Less
  • Research Projects

    (8 results)
  • Research Products

    (25 results)
  • Co-Researchers

    (14 People)
  •  ゼロヒャクの感受性時刻差を示す金属毒性に対する時計遺伝子の関与に関する研究Principal Investigator

    • Principal Investigator
      吉岡 弘毅
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58020:Hygiene and public health-related: including laboratory approach
    • Research Institution
      Gihu University of Medical Science
  •  Studying on contributing to ensuring fertility and avoiding developmental toxicity risks in paediatric cancer patients

    • Principal Investigator
      横田 理
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      National Institute of Health Sciences
  •  ゴルジ体の機能阻害が誘導する遊離および結合型N-glycanの代謝フラックスの時空間解析

    • Principal Investigator
      篠原 康郎
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
    • Research Institution
      Kinjo Gakuin University
  •  iPS細胞のエクソソームを用いたT細胞制御による自己免疫疾患の新規治療法開発

    • Principal Investigator
      緒方 謙一
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Kyushu University
  •  diurnal variation of cisplatin-induced anti-tumor effect and renal toxicityPrincipal Investigator

    • Principal Investigator
      YOSHIOKA HIROKI
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 47060:Clinical pharmacy-related
    • Research Institution
      Gihu University of Medical Science
  •  Basic and clinical research aiming at optimization of blood sugar management for shift workers

    • Principal Investigator
      吉川 昌江
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58010:Medical management and medical sociology-related
    • Research Institution
      Kinjo Gakuin University
  •  Comprehensive analysis of glycan metabolic networks by chemical glycomic approach

    • Principal Investigator
      Shinohara Yasuro
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
    • Research Institution
      Kinjo Gakuin University
  •  Molecular mechanism of testicular dysfunction induced by titanium dioxide nanoparticles

    • Principal Investigator
      Miura Nobuhiko
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Risk sciences of radiation and chemicals
    • Research Institution
      National Institute of Occupational Safety and Health,Japan

All 2024 2023 2022 2021 2019 2017

All Journal Article Presentation

  • [Journal Article] Extracellular vesicles of iPS cells highly capable of producing HGF and TGF-β1 can attenuate Sj?gren's syndrome via innate immunity regulation2024

    • Author(s)
      Ogata Kenichi、Moriyama Masafumi、Kawado Tatsuya、Yoshioka Hiroki、Yano Aiko、Matsumura-Kawashima Mayu、Nakamura Seiji、Kawano Shintaro
    • Journal Title

      Cellular Signalling

      Volume: 113 Pages: 110980-110980

    • DOI

      10.1016/j.cellsig.2023.110980

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K18401, KAKENHI-PROJECT-22K19631, KAKENHI-PROJECT-21K10075, KAKENHI-PROJECT-22K10221
  • [Journal Article] Let-7c-5p associate with inhibition of phenobarbital-induced cell proliferation in human palate cells2024

    • Author(s)
      Tsukiboshi Yosuke、Noguchi Azumi、Horita Hanane、Mikami Yurie、Yokota Satoshi、Ogata Kenichi、Yoshioka Hiroki
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 696 Pages: 149516-149516

    • DOI

      10.1016/j.bbrc.2024.149516

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K10221
  • [Journal Article] Involvement of <i>microRNA-4680-3p</i> against phenytoin-induced cell proliferation inhibition in human palate cells2024

    • Author(s)
      Yosuke Tsukiboshi , Hanane Horita , Yurie Mikami , Azumi Noguchi , Satoshi Yokota , Kenichi Ogata , Hiroki Yoshioka
    • Journal Title

      The Journal of Toxicological Sciences

      Volume: 49 Issue: 1 Pages: 1-8

    • DOI

      10.2131/jts.49.1

    • ISSN
      0388-1350, 1880-3989
    • Language
      English
    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K19235, KAKENHI-PROJECT-22K10221
  • [Journal Article] Exposure to brefeldin A induces unusual expression of hybrid- and complex-type free N-glycans in HepG2 cells2023

    • Author(s)
      Sugiura Kanako、Kawai Yuho、Yamamoto Arisa、Yoshioka Hiroki、Kiyohara Yuika、Iida Ayaka、Ozawa Yurika、Nishikawa Mai、Miura Nobuaki、Hanamatsu Hisatoshi、Furukawa Jun-ichi、Shinohara Yasuro
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - General Subjects

      Volume: 1867 Issue: 5 Pages: 130331-130331

    • DOI

      10.1016/j.bbagen.2023.130331

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K12124, KAKENHI-PROJECT-18H02565, KAKENHI-PROJECT-23K24759
  • [Journal Article] Copper-induced diurnal hepatic toxicity is associated with <i>Cry2</i> and <i>Per1</i> in mice2023

    • Author(s)
      Sarah Tominaga, Hiroki Yoshioka, Satoshi Yokota, Yosuke Tsukiboshi, Masumi Suzui, Makoto Nagai, Hirokazu Hara, Tohru Maeda, Nobuhiko Miura
    • Journal Title

      Environ Health Prev Med

      Volume: 28 Issue: 0 Pages: 78-78

    • DOI

      10.1265/ehpm.23-00205

    • ISSN
      1342-078X, 1347-4715
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K15328
  • [Journal Article] Involvement of <i>Bmal1</i> and <i>Clock</i> in Bromobenzene Metabolite-Induced Diurnal Renal Toxicity2023

    • Author(s)
      Yoshioka Hiroki、Yokota Satoshi、Tominaga Sarah、Tsukiboshi Yosuke、Suzui Masumi、Shinohara Yasuro、Yoshikawa Masae、Sasaki Hayato、Sasaki Nobuya、Maeda Tohru、Miura Nobuhiko
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 46 Issue: 6 Pages: 824-829

    • DOI

      10.1248/bpb.b23-00072

    • ISSN
      0918-6158, 1347-5215
    • Year and Date
      2023-06-01
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K10416, KAKENHI-PROJECT-23K05603, KAKENHI-PROJECT-22K15328
  • [Journal Article] Evaluation of the context of downstream N- and free N-glycomic alterations induced by swainsonine in HepG2 cells2022

    • Author(s)
      Morikawa Chie、Sugiura Kanako、Kondo Keina、Yamamoto Yurie、Kojima Yuma、Ozawa Yurika、Yoshioka Hiroki、Miura Nobuaki、Piao Jinhua、Okada Kazue、Hanamatsu Hisatoshi、Tsuda Masumi、Tanaka Shinya、Furukawa Jun-ichi、Shinohara Yasuro
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - General Subjects

      Volume: 1866 Issue: 9 Pages: 130168-130168

    • DOI

      10.1016/j.bbagen.2022.130168

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K12124, KAKENHI-PROJECT-19H01171, KAKENHI-PROJECT-21H03802, KAKENHI-PROJECT-21K19878, KAKENHI-PROJECT-18H02565
  • [Journal Article] Impaired GATE16-mediated exocytosis in exocrine tissues causes Sj?gren’s syndrome-like exocrinopathy2022

    • Author(s)
      Suzuki Akiko、Iwaya Chihiro、Ogata Kenichi、Yoshioka Hiroki、Shim Junbo、Tanida Isei、Komatsu Masaaki、Tada Norihiro、Iwata Junichi
    • Journal Title

      Cellular and Molecular Life Sciences

      Volume: 79 Issue: 6 Pages: 307-307

    • DOI

      10.1007/s00018-022-04334-x

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K10221, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-21H04771, KAKENHI-PROJECT-18K05691, KAKENHI-ORGANIZER-19H05705, KAKENHI-PLANNED-19H05706, KAKENHI-PUBLICLY-22H04652
  • [Journal Article] Different Renal Chronotoxicity of Bromobenzene and Its Intermediate Metabolites in Mice2021

    • Author(s)
      Yoshioka Hiroki、Tominaga Sarah、Nishikawa Mai、Shinohara Yasuro、Nakao Makoto、Yoshikawa Masae、Maeda Tohru、Miura Nobuhiko
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 44 Issue: 1 Pages: 150-153

    • DOI

      10.1248/bpb.b20-00694

    • NAID

      130007965324

    • ISSN
      0918-6158, 1347-5215
    • Year and Date
      2021-01-01
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K10416
  • [Journal Article] Impairment of fertilization efficiency in mice following nano-sized titanium exposure2019

    • Author(s)
      Nobuhiko Miura, Katsumi Ohtani, Tatsuya Hasegawa, Gi-Wook Hwang, Hiroki Yoshioka
    • Journal Title

      Fund Toxicol Sci

      Volume: 6 Pages: 113-116

    • NAID

      130007649489

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H02829
  • [Journal Article] Biphasic adverse effect of titanium nanoparticles on testicular function in mice2019

    • Author(s)
      Nobuhiko Miura, Katsumi Ohtani, Tatsuya Hasegawa, Hiroki Yoshioka & Gi-Wook Hwang
    • Journal Title

      Scientific Report

      Volume: 9 Issue: 1 Pages: 14373-14380

    • DOI

      10.1038/s41598-019-50741-9

    • Open Access
    • Data Source
      KAKENHI-PROJECT-15H02829
  • [Journal Article] High sensitivity of testicular function to titanium nanoparticles2017

    • Author(s)
      Nobuhiko Miura, Katsumi Ohtani, Tatsuya Hasegawa, Hiroki Yoshioka, Gi-Wook Hwang
    • Journal Title

      The Journal of Toxicological Sciences

      Volume: 42 Issue: 3 Pages: 359-366

    • DOI

      10.2131/jts.42.359

    • NAID

      130006865652

    • ISSN
      0388-1350, 1880-3989
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02829
  • [Presentation] 歯髄幹細胞由来の細胞外小胞を付加した人工神経を使った新たな末梢神経再生療法の開発2024

    • Author(s)
      緒方 謙一、矢野 亜衣子、森山 雅文、吉岡 弘毅、川戸 達也、川野 真太郎
    • Organizer
      第23回 日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-22K10221
  • [Presentation] α-グルコシダーゼ阻害剤がHepG2細胞のN-グリカン、遊離オリゴ糖、スフィンゴ糖脂質の発現に与える影響2024

    • Author(s)
      廣瀬 郁実、田中 志歩、榊原 真帆、田上 明里、渡邊 真里菜、吉岡 弘毅、篠原 康郎
    • Organizer
      日本薬学会第144年会
    • Data Source
      KAKENHI-PROJECT-23K06087
  • [Presentation] ゴルジ体ストレス誘導剤のBrefeldin AとGolgicide AがHepG2細胞のN-glycan, 遊離N-glycanの代謝に与える影響2024

    • Author(s)
      加田 真彩、寺川 実那、廣瀬 郁実、田中 志歩、清原 由衣可、杉浦 花菜子、川合 裕穂、山本 有紗、吉岡 弘毅、篠原 康郎
    • Organizer
      日本薬学会第144年会
    • Data Source
      KAKENHI-PROJECT-23K06087
  • [Presentation] MonensinやNigericinはHepG2細胞においてモノアンテナ型やコンプレックス型の遊離N-グリカンの発現を誘導する2024

    • Author(s)
      西村 音々、廣瀬 郁実、田中 志歩、渡邊 真里菜、清原 由衣可、杉浦 花菜子、山本 有紗、川合 裕穂、吉岡 弘毅、篠原 康郎
    • Organizer
      日本薬学会第144年会
    • Data Source
      KAKENHI-PROJECT-23K06087
  • [Presentation] シスプラチンの感受性時刻差における抗腫瘍作用と腎障害の統合評価2024

    • Author(s)
      吉岡弘毅、三上友理恵、松下幸平、横田理、富永サラ、前田徹、三浦伸彦
    • Organizer
      日本薬学会第144年会(横浜)
    • Data Source
      KAKENHI-PROJECT-22K15328
  • [Presentation] シスプラチンによる急性腎毒性と時計遺伝子の関与2023

    • Author(s)
      吉岡弘毅
    • Organizer
      日本薬学会 第143年会(札幌)
    • Data Source
      KAKENHI-PROJECT-22K15328
  • [Presentation] シスプラチンによる腎障害に対する時計遺伝子発現変化の影響2023

    • Author(s)
      吉岡弘毅、富永サラ、横田理、前田徹、三浦伸彦
    • Organizer
      第六回医薬品毒性機序研究会
    • Data Source
      KAKENHI-PROJECT-22K15328
  • [Presentation] シスプラチンによる急性腎障害の感受性時刻差に関与する因子の探索2023

    • Author(s)
      富永サラ、吉岡弘毅、杉本昌弘、三浦伸彦、前田徹
    • Organizer
      第94回日本衛生学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K15328
  • [Presentation] Brefeldin AはHepG2細胞においてユニークなハイブリッド型やコンプレックス型の遊離N-glycanの発現を誘導する2023

    • Author(s)
      清原 由衣可、杉浦 花菜子、川合 裕穂、山本 有紗、飯田 彩華、小澤 優里香、吉岡 弘毅、篠原 康郎
    • Organizer
      日本薬学会第143年会
    • Data Source
      KAKENHI-PROJECT-18H02565
  • [Presentation] Titanium dioxide nanopaticles-induced testicular dysfunction is mediated by anatase titanium dioxide2019

    • Author(s)
      Hiroki Yoshioka, Nobuhiko Miura
    • Organizer
      フォーラム2018 衛生薬学・環境トキシコロジー 日韓次世代シンポジウム
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02829
  • [Presentation] 酸化チタンナノ粒子による急性精巣機能障害の誘発機構2019

    • Author(s)
      三浦伸彦,田中廣輝,北條理恵子,大谷勝己,吉岡弘毅
    • Organizer
      第45回日本毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-15H02829
  • [Presentation] 酸化チタンナノ粒子による精巣障害および肝障害の比較2017

    • Author(s)
      三浦伸彦,北條理恵子,吉岡弘毅,大谷勝己
    • Organizer
      生命科学系学会合同年次大会(ConBio2017)
    • Data Source
      KAKENHI-PROJECT-15H02829
  • [Presentation] マウスにおける酸化チタンの雄性生殖系への影響2017

    • Author(s)
      大谷勝己,北條理恵子,吉岡弘毅,三浦伸彦
    • Organizer
      生命科学系学会合同年次大会(ConBio2017)
    • Data Source
      KAKENHI-PROJECT-15H02829
  • 1.  Shinohara Yasuro (20374192)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 2.  Miura Nobuhiko (20229644)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 3.  古川 潤一 (30374193)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  大谷 勝己 (50333373)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  吉川 昌江 (80581389)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  緒方 謙一 (30778858)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 7.  森山 雅文 (20452774)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 8.  中村 誠司 (60189040)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  横田 理 (70706605)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  佐藤 卓也 (70599505)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  鹿島 誠 (10780562)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  宮宗 秀伸 (80422252)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  OHTANI Katsumi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 5 results
  • 14.  三浦 信明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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