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OSHIMA NAOHIRO  大嶋 直浩

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OSHIMA Naohiro  大嶋 直浩

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Researcher Number 30757133
Other IDs
Affiliation (Current) 2025: 国立医薬品食品衛生研究所, 生活衛生化学部, 主任研究官
Affiliation (based on the past Project Information) *help 2022 – 2023: 国立医薬品食品衛生研究所, 生活衛生化学部, 主任研究官
2020 – 2021: 国立医薬品食品衛生研究所, 生活衛生化学部, 研究員
2018 – 2019: 東京理科大学, 薬学部薬学科, 助教
Review Section/Research Field
Principal Investigator
Basic Section 47050:Environmental and natural pharmaceutical resources-related
Keywords
Principal Investigator
バイカリン / 副作用 / オウゴン / 小柴胡湯 / 肝機能障害 / 副作用の制御 / 副作用制御 / バイカレイン / 生薬 / 抽出量変化 … More / フラボノイド / 生薬間相互作用 / 間質性肺炎 / 生薬の組み合わせ / 肝細胞毒性 / トランスポーター / 含有量 / 改善策 Less
  • Research Projects

    (2 results)
  • Research Products

    (6 results)
  • Co-Researchers

    (2 People)
  •  Strategy to control the side effects of Scutellaria Root and their applicationsPrincipal Investigator

    • Principal Investigator
      大嶋 直浩
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47050:Environmental and natural pharmaceutical resources-related
    • Research Institution
      National Institute of Health Sciences
  •  Combination study of the optimal crude drugs to prevent interstitial pneumonia with Scutellaria Root-containing Kampo formulaePrincipal Investigator

    • Principal Investigator
      OSHIMA Naohiro
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 47050:Environmental and natural pharmaceutical resources-related
    • Research Institution
      National Institute of Health Sciences
      Tokyo University of Science

All 2024 2021 2020 2018

All Journal Article Presentation

  • [Journal Article] Scutellaria Root extract-induced hepatocytotoxicity can be controlled by regulating its baicalin content2024

    • Author(s)
      1.Naohiro Oshima,* Kosuke Kusamori, Ryo Takasaki, Moe Takeda, Yuri Katsurada, Takumi Nose, Kazuki Okoshi, Makiya Nishikawa,* Noriyasu Hada
    • Journal Title

      Journal of Natural Medicines

      Volume: ー Issue: 4 Pages: 978-984

    • DOI

      10.1007/s11418-024-01814-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K06676
  • [Journal Article] Synergistic effect of baicalein, wogonin and oroxylin A mixture; multistep inhibition of the NF-kV signaling pathway contributes to an anti-inflammatory effect of Scutellaria root flavonoids2018

    • Author(s)
      T. Shimizu, N. Shibuya, Y. Narukawa, N. Oshima, N. Hada and F. Kiuchi.
    • Journal Title

      J. Nat. Med.

      Volume: 72 Issue: 1 Pages: 181-191

    • DOI

      10.1007/s11418-017-1129-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08347, KAKENHI-PROJECT-18K14937
  • [Journal Article] Quantitative analysis of anti-inflammatory activity of orengedokuto Ⅱ: Berberine is responsible for inhibition of NO production2018

    • Author(s)
      Naohiro Oshima, Tomofumi Shimizu, Yuji Narukawa, Noriyasu Hada, and Fumiyuki Kiuchi
    • Journal Title

      Journal of Natural Medicines

      Volume: 72(3) Issue: 3 Pages: 706-714

    • DOI

      10.1007/s11418-018-1209-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08347, KAKENHI-PROJECT-18K06721, KAKENHI-PROJECT-18K14937
  • [Presentation] 生薬の配合によるオウゴン由来フラボノイドの抽出量の変化2021

    • Author(s)
      熊谷朝日、大嶋直浩、羽田紀康
    • Organizer
      日本薬学会141回年会
    • Data Source
      KAKENHI-PROJECT-18K14937
  • [Presentation] 生薬の配合によるオウゴン由来フラボノイドの抽出量変化(3)2021

    • Author(s)
      武田萌、大嶋直浩、羽田紀康
    • Organizer
      日本生薬学会第67回年会
    • Data Source
      KAKENHI-PROJECT-18K14937
  • [Presentation] 生薬の配合によるオウゴン由来フラボノイドの抽出量変化2020

    • Author(s)
      武田 萌、大嶋 直浩、羽田 紀康
    • Organizer
      日本薬学会第140年会
    • Data Source
      KAKENHI-PROJECT-18K14937
  • 1.  西川 元也 (40273437)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 2.  羽田 紀康 (70296531)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results

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