Kubota Manabu 久保田学

Researcher Number	30760368
Other IDs
Affiliation (Current)	2025: 京都大学, 医学研究科, 講師
Affiliation (based on the past Project Information) *help	2022 – 2024: 京都大学, 医学研究科, 講師 2021 – 2022: 京都大学, 医学研究科, 助教 2020: 京都大学, 医学研究科, 特定助教 2018 – 2019: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所脳機能イメージング研究部, 研究員(任常) 2016 – 2017: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所脳機能イメージング研究部, 博士研究員(任常) 2015: 国立研究開発法人放射線医学総合研究所, 分子イメージング研究センター, 博士研究員
Review Section/Research Field	Principal Investigator Basic Section 52030:Psychiatry-related / Psychiatric science Except Principal Investigator Basic Section 10030:Clinical psychology-related / Basic Section 51020:Cognitive and brain science-related
Keywords	Principal Investigator 精神疾患 / 老年精神医学 / アミロイド / タウ / 陽電子放出断層撮像 / phosphodiesterase / [18F]MNI659 / cognition / striatum / MRS … More / PET / PDE10A / ホスホジエステラーゼ / 統合失調症 / グルタミン酸 / ドーパミン … More Except Principal Investigator 社会適応 / ランダム化比較試験 / 自閉スペクトラム症 / 統合失調症 / 神経基盤 / 社会認知 / ７TMRI / 神経心理 / 脳科学 / 神経心理学 / PET / MRI / 脳萎縮 / 外傷性脳損傷 Less

統合失調症と自閉スペクトラム症への社会認知トレーニングの効果増強：神経基盤の解明
- Principal Investigator
  
  大塚貞男
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 10030:Clinical psychology-related
- Research Institution
  Sugiyama Jogakuen University
  Kyoto University
タウ・アミロイドPETおよび7テスラMRI/MRSによる中高年期精神疾患の層別化Principal Investigator
- Principal Investigator
  
  久保田学
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Kyoto University
Investigation about underpinning neural mechanisms of sequelae and brain atrophy after brain injury
- Principal Investigator
  
  上田敬太
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51020:Cognitive and brain science-related
- Research Institution
  Kyoto Koka Women's University
Classification of schizophrenia-related disorders by multimodal neuroimaging assessments of PDE10APrincipal Investigator
- Principal Investigator
  
  Kubota Manabu
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Kyoto University
  National Institutes for Quantum and Radiological Science and Technology
Associations between central glutamatergic neurotransmission and cognition in schizophrenia using novel PET ligands related to AMPAPrincipal Investigator
- Principal Investigator
  
  Kubota Manabu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  National Institutes for Quantum and Radiological Science and Technology
脳内ドーパミン神経伝達機能と白質線維統合性の関連についての研究Principal Investigator
- Principal Investigator
  
  久保田学
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Psychiatric science
- Research Institution
  National Institute of Radiological Sciences

All 2024 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation Book

[Book] 『統合失調症治療の新たなストラテジー第２版』「Part 2-4. 画像からみた統合失調症の脳機能」2021
- Author(s)
  久保田　学
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-19K17101
[Book] 日本生物学的精神医学会誌 2018. Vol.29, No.4. Mini Review『統合失調症の脳構造および分子神経基盤』2018
- Author(s)
  久保田学
- Total Pages
  1
- Publisher
  新興医学出版社
- Data Source
  KAKENHI-PROJECT-16K19790
[Journal Article] In vivo PET classification of tau pathologies in patients with frontotemporal dementia2024
- Author(s)
  Kubota Manabu、Endo Hironobu、Takahata Keisuke、Tagai Kenji、Suzuki Hisaomi、Onaya Mitsumoto、Sano Yasunori、Yamamoto Yasuharu、Kurose Shin、Matsuoka Kiwamu、Seki Chie、Shinotoh Hitoshi、Kawamura Kazunori、Zhang Ming-Rong、Takado Yuhei、Shimada Hitoshi、Higuchi Makoto
- Journal Title
  
  Brain Communications
  
  Volume: 6 Issue: 2
- DOI
  10.1093/braincomms/fcae075
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19636, KAKENHI-PROJECT-23K24259
[Journal Article] Two pathways differentially linking tau depositions, oxidative stress, and neuronal loss to apathetic phenotypes in progressive supranuclear palsy2023
- Author(s)
  Matsuoka Kiwamu、Takado Yuhei、Tagai Kenji、Kubota Manabu、Sano Yasunori、Takahata Keisuke、Ono Maiko、Seki Chie、Matsumoto Hideki、Endo Hironobu、Shinotoh Hitoshi、Sahara Yasuka、Obata Takayuki、Near Jamie、Kawamura Kazunori、Zhang Ming-Rong、Suhara Tetsuya、Shimada Hitoshi、Higuchi Makoto
- Journal Title
  
  Journal of the Neurological Sciences
  
  Volume: 444 Pages: 120514-120514
- DOI
  10.1016/j.jns.2022.120514
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07529, KAKENHI-PROJECT-22K19636, KAKENHI-PROJECT-22H04926, KAKENHI-PROJECT-18K07543, KAKENHI-PROJECT-20K07935, KAKENHI-PROJECT-20K16681, KAKENHI-PROJECT-23K24259
[Journal Article] PET-based classification of corticobasal syndrome.2022
- Author(s)
  Nakano Y, Shimada H, Shinotoh H, Hirano S, Tagai K, Sano Y, Yamamoto Y, Endo H, Matsuoka K, Takahata K, Kubota M, Takado Y, Kimura Y, Ichise M, Ono M, Sahara N, Kawamura K, Zhang MR, Kuwabara S, Suhara T, Higuchi M.
- Journal Title
  
  Parkinsonism & related disorders
  
  Volume: 98 Pages: 92-98
- DOI
  10.1016/j.parkreldis.2022.04.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07935, KAKENHI-PUBLICLY-21H00446, KAKENHI-PROJECT-23K24259
[Journal Article] Positron Emission Tomography Assessments of Phosphodiesterase 10A in Patients With Schizophrenia2022
- Author(s)
  Kubota Manabu、Takahata Keisuke、Matsuoka Kiwamu、Sano Yasunori、Yamamoto Yasuharu、Tagai Kenji、Tarumi Ryosuke、Suzuki Hisaomi、Kurose Shin、Nakajima Shinichiro、Shiwaku Hiroki、Seki Chie、Kawamura Kazunori、Zhang Ming-Rong、Takahashi Hidehiko、Takado Yuhei、Higuchi Makoto
- Journal Title
  
  Schizophrenia Bulletin
  
  Volume: ー Issue: 3 Pages: 688-696
- DOI
  10.1093/schbul/sbac181
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15757, KAKENHI-PROJECT-20KK0193, KAKENHI-PROJECT-20K07935, KAKENHI-PROJECT-19K17101, KAKENHI-PROJECT-19K08011, KAKENHI-PROJECT-22K07553, KAKENHI-PROJECT-23K24263
[Journal Article] High-Contrast In Vivo Imaging of Tau Pathologies in Alzheimer’s and Non-Alzheimer’s Disease Tauopathies2021
- Author(s)
  Tagai K, Ono M, Kubota M, Kitamura S, Takahata K, Seki C, Takado Y, Shinotoh H, Sano Y, Yamamoto Y, Matsuoka K, Takuwa H, Shimojo M, (24人省略), Shimada H.
- Journal Title
  
  Neuron
  
  Volume: 109 Issue: 1 Pages: 42-58
- DOI
  10.1016/j.neuron.2020.09.042
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07543, KAKENHI-PROJECT-19K06896, KAKENHI-PROJECT-20K06929, KAKENHI-PROJECT-19K17101, KAKENHI-PUBLICLY-19H05437, KAKENHI-PROJECT-18K06542, KAKENHI-PROJECT-18K07777, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-19H03362, KAKENHI-PROJECT-19H03583
[Journal Article] A first-in-human study of 11C-MTP38, a novel PET ligand for phosphodiesterase 72021
- Author(s)
  Kubota Manabu、Seki Chie、Kimura Yasuyuki、Takahata Keisuke、Shimada Hitoshi、Takado Yuhei、Matsuoka Kiwamu、Tagai Kenji、Sano Yasunori、Yamamoto Yasuharu、Okada Maki、Kikuchi Tatsuya、Ichise Masanori、Kawamura Kazunori、Zhang Ming-Rong、Higuchi Makoto
- Journal Title
  
  European Journal of Nuclear Medicine and Molecular Imaging
  
  Volume: 41 Issue: 11 Pages: 2928-2943
- DOI
  10.1177/0271678x211004150
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17101, KAKENHI-PUBLICLY-21H05705, KAKENHI-PROJECT-20K06929, KAKENHI-PROJECT-20K07935, KAKENHI-PROJECT-21K07580, KAKENHI-PROJECT-23K21399
[Journal Article] Relationship between regional gray matter volumes and dopamine D2 receptor and transporter in living human brains2021
- Author(s)
  Kurose Shin、Kubota Manabu、Takahata Keisuke、Yamamoto Yasuharu、Fujiwara Hironobu、Kimura Yasuyuki、Ito Hiroshi、Takeuchi Hiroyoshi、Mimura Masaru、Suhara Tetsuya、Higuchi Makoto
- Journal Title
  
  Human Brain Mapping
  
  Volume: - Issue: 12 Pages: 4048-4058
- DOI
  10.1002/hbm.25538
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17071, KAKENHI-PROJECT-19H03583, KAKENHI-PROJECT-20K08031, KAKENHI-PROJECT-19K17101
[Journal Article] Differential associations of dopamine synthesis capacity with the dopamine transporter and D2 receptor availability as assessed by PET in the living human brain2021
- Author(s)
  Yamamoto Yasuharu、Takahata Keisuke、Kubota Manabu、Takano Harumasa、Takeuchi Hiroyoshi、Kimura Yasuyuki、Sano Yasunori、Kurose Shin、Ito Hiroshi、Mimura Masaru、Higuchi Makoto
- Journal Title
  
  NeuroImage
  
  Volume: 226 Pages: 117543-117543
- DOI
  10.1016/j.neuroimage.2020.117543
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17101, KAKENHI-PROJECT-19K17071, KAKENHI-PROJECT-20K08031
[Journal Article] Treatment effects on neurometabolite levels in schizophrenia: A systematic review and meta-analysis of proton magnetic resonance spectroscopy studies.2020
- Author(s)
  Manabu Kubota, Sho Moriguchi, Keisuke Takahata, Shinichiro Nakajima, Nobuyuki Horita
- Journal Title
  
  Schizophrenia Research
  
  Volume: - Pages: 122-132
- DOI
  10.1016/j.schres.2020.03.069
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17101, KAKENHI-PROJECT-20KK0193, KAKENHI-PROJECT-18H02755, KAKENHI-PROJECT-20H03606
[Journal Article] Treatment effects on neurometabolite levels in schizophrenia: A meta-analysis dataset of proton magnetic resonance spectroscopy2020
- Author(s)
  Kubota Manabu、Moriguchi Sho、Takahata Keisuke、Nakajima Shinichiro、Horita Nobuyuki
- Journal Title
  
  Data in Brief
  
  Volume: 31 Pages: 105862-105862
- DOI
  10.1016/j.dib.2020.105862
- NAID
  120006956392
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17101, KAKENHI-PROJECT-20KK0193, KAKENHI-PROJECT-18H02755, KAKENHI-PROJECT-20H03606
[Journal Article] High-contrast in-vivo imaging of tau pathologies in Alzheimer’s disease and non-Alzheimer’s disease tauopathies.2020
- Author(s)
  Kenji Tagai*, Maiko Ono*, Manabu Kubota*, et al. (*co-first authors)
- Journal Title
  
  medRxiv
  
  Volume: -
- DOI
  10.1101/2020.03.05.20028407
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17101
[Journal Article] Overlapping but Asymmetrical Relationships Between Schizophrenia and Autism Revealed by Brain Connectivity.2020
- Author(s)
  Yujiro Yoshihara, Giuseppe Lisi, Noriaki Yahata, Junya Fujino, Yukiko Matsumoto, Jun Miyata, Gen-Ichi Sugihara, Shin-Ichi Urayama, Manabu Kubota et al.
- Journal Title
  
  Schizophrenia Bulletin
  
  Volume: 4 Issue: 5 Pages: 1210-1218
- DOI
  10.1093/schbul/sbaa021
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17101, KAKENHI-PUBLICLY-18H05130, KAKENHI-PROJECT-20K21567, KAKENHI-PLANNED-16H06572, KAKENHI-PUBLICLY-20H05064, KAKENHI-PROJECT-17H04248, KAKENHI-PROJECT-19H03583, KAKENHI-PLANNED-16H06399
[Journal Article] A human PET study of [11C]HMS011, a potential radioligand for AMPA receptors2018
- Author(s)
  Keisuke Takahata et al.,
- Journal Title
  
  EJNMMI research
  
  Volume: 16 Issue: 1 Pages: 63-63
- DOI
  10.1186/s13550-017-0313-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19789, KAKENHI-PROJECT-16K19790, KAKENHI-PROJECT-16H05324, KAKENHI-PROJECT-15K09977
[Journal Article] Reward related brain structures are smaller in patients with schizophrenia and comorbid metabolic syndrome2018
- Author(s)
  de Nijs J, Schnack HG, Koevoets GJ, Kubota M, de Kahn RS, van Haren NEM, Cahn W
- Journal Title
  
  Acta Psychiatrica Scandinavica
  
  Volume: 138 Issue: 6 Pages: 581-590
- DOI
  10.1111/acps.12955
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19790
[Presentation] PET、MRIを用いた精神疾患の脳画像研究2024
- Author(s)
  久保田学
- Organizer
  第26回日本ヒト脳機能マッピング学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24259
[Presentation] In vivo characterization of tau accumulation in patients with frontotemporal dementia: A PET study with 18F-florzolotau.2023
- Author(s)
  Manabu Kubota, Hironobu Endo, Keisuke Takahata, Kenji Tagai, Hisaomi Suzuki, Mitsumoto Onaya, Yasunori Sano, Yasuharu Yamamoto, Shin Kurose, Kiwamu Matsuoka, Chie Seki, Hitoshi Shinotoh, Kazunori Kawamura, Ming-Rong Zhang, Yuhei Takado, Hitoshi Shimada, Makoto Higuchi
- Organizer
  Alzheimer’s Association International Conference 2023 (AAIC 2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24259
[Presentation] Cerebral retention patterns of 18F-florzolotau (18F-APN-1607) in the former professional boxers: A longitudinal PET study2023
- Author(s)
  Keisuke Takahata, Manabu Kubota, Kenji Tagai, Hironobu Endo, Mari Miyata, Fumie Saito, Harutsugu Tatebe, Kiwamu Matsuoka, Shin Kurose, Ichihashi M, Kataoka Y, Hirata K, Matsumoto H, Seki C, Kokubo N, Shinotoh H, Oya M, Sano Y, Yamamoto Y, Kawamura K, Zhang MR, Tabuchi H, Sahara N, Takahiko Tokuda, Mimura M, Higuchi M
- Organizer
  Alzheimer’s Association International Conference 2023 (AAIC 2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24259
[Presentation] PETを用いた統合失調症患者におけるホスホジエステラーゼ10A（PDE10A）の評価2022
- Author(s)
  久保田学, 高畑圭輔, 松岡究, 佐野康徳, 山本保天, 互健二, 垂水良介, 鈴木寿臣, 黒瀬心, 中島振一郎, 塩飽裕紀, 関千江, 河村和紀, 張明栄, 髙橋英彦, 高堂裕平, 樋口真人
- Organizer
  第44回日本生物学的精神医学会年会・第32回日本臨床精神神経薬理学会年会・第52回日本神経精神薬理学会年会・第6回日本精神薬学会総会 4学会合同年会（BPCNPNPPP4学会合同年会）
- Data Source
  KAKENHI-PROJECT-19K17101
[Presentation] Positron emission tomography assessments of phosphodiesterase 10A in patients with schizophrenia2022
- Author(s)
  Manabu Kubota, Keisuke Takahata, Kiwamu Matsuoka, Yasunori Sano, Yasuharu Yamamoto, Kenji Tagai, Ryosuke Tarumi, Hisaomi Suzuki, Shin Kurose, Shinichiro Nakajima, Hiroki Shiwaku, Chie Seki, Kazunori Kawamura, Ming-Rong Zhang, Hidehiko Takahashi, Yuhei Takado, Makoto Higuchi
- Organizer
  Annual meeting of Society for Neuroscience (Neuroscience 2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17101
[Presentation] 線条体ドーパミン機能に着目した統合失調症の病態理解 -PET研究の知見を中心に-2022
- Author(s)
  久保田学
- Organizer
  第44回日本生物学的精神医学会年会・第32回日本臨床精神神経薬理学会年会・第52回日本神経精神薬理学会年会・第6回日本精神薬学会総会 4学会合同年会（BPCNPNPPP4学会合同年会）
- Data Source
  KAKENHI-PROJECT-19K17101
[Presentation] 前頭側頭型認知症および老年期精神疾患の臨床タウPET研究2022
- Author(s)
  久保田学
- Organizer
  第23回日本脳神経核医学研究会（第62回日本核医学会学術総会）
- Data Source
  KAKENHI-PROJECT-23K24259
[Presentation] 前頭側頭型認知症および老年期精神病におけるタウイメージング2022
- Author(s)
  久保田学
- Organizer
  第44回日本生物学的精神医学会年会・第32回日本臨床精神神経薬理学会年会・第52回日本神経精神薬理学会年会・第6回日本精神薬学会総会 4学会合同年会（BPCNPNPPP4学会合同年会）
- Data Source
  KAKENHI-PROJECT-23K24259
[Presentation] ヒト生体脳の標的分子可視化技術に基づく精神神経疾患の新規治療戦略（学術奨励賞受賞講演）2021
- Author(s)
  久保田学
- Organizer
  第51回日本神経精神薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K17101
[Presentation] 統合失調症において治療が脳内代謝物におよぼす影響についての検討：MRS研究の系統的レビューとメタ解析2021
- Author(s)
  久保田学、森口翔、高畑圭輔、中島振一郎、堀田信之
- Organizer
  第15回統合失調症学会
- Data Source
  KAKENHI-PROJECT-19K17101
[Presentation] 食事およびグルコース摂取に伴う脳内グルタミン酸の動的変化：ヒトおよび動物における生体内マルチモーダル評価2021
- Author(s)
  久保田学、木村泰之、下條雅文、高堂裕平、Joao M.N. Duarte、田桑弘之、関千江、島田斉、高畑圭輔、北村聡一郎、森口翔、互健二、小畠隆行、中原仁、冨田裕、徳永正希、前田純、市瀬正則、須原哲也、樋口真人
- Organizer
  第43回日本生物学的精神医学会・第51回日本神経精神薬理学会年会合同年会(BPNP2021)
- Data Source
  KAKENHI-PROJECT-19K17101
[Presentation] A first-in-human study of [11C]MTP38, a novel PET ligand for phosphodiesterase 7.2021
- Author(s)
  Kubota M, Seki C, Kimura Y, Takahata K, Shimada H, Takado Y, Matsuoka K, Tagai K, Sano Y, Yamamoto Y, Kikuchi T, Ichise M, Kawamura K, Zhang MR, Higuchi M
- Organizer
  CINP 2021 Virtual World Congress; 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17101
[Presentation] ホスホジエステラーゼ７の新規PETリガンド、11C-MTP38を用いたfirst in human試験2021
- Author(s)
  久保田学、関千江、木村泰之、高畑圭輔、島田斉、高堂裕平、松岡究、互健二、佐野康徳、山本保天、岡田真希、菊池達矢、市瀬正則、河村和紀、張明栄、樋口真人
- Organizer
  第43回日本生物学的精神医学会・第51回日本神経精神薬理学会年会合同年会(BPNP2021)
- Data Source
  KAKENHI-PROJECT-19K17101
[Presentation] Progressive brain change and its association with IQ change in schizophrenia2019
- Author(s)
  Manabu Kubota
- Organizer
  14th World Congress of Biological Psychiatry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17101
[Presentation] 統合失調症の脳構造および分子神経基盤に関する統合的画像研究2019
- Author(s)
  久保田　学
- Organizer
  第 41回日本生物学的精神医学会　若手研究者育成プログラム
- Data Source
  KAKENHI-PROJECT-19K17101
[Presentation] Alterations of central metabotropic glutamate receptor 5 binding and glutamate concentrations by food intake2019
- Author(s)
  Manabu Kubota et al.
- Organizer
  14th World Congress of Biological Psychiatry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17101
[Presentation] Treatment effects on neurometabolite levels in schizophrenia: A systematic review and meta-analysis of proton magnetic resonance spectroscopy studies.2019
- Author(s)
  Manabu Kubota et al.
- Organizer
  6th Congress of Asian College of Neuropsychopharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17101
[Presentation] PET and MRI imaging in schizophrenia: How can we preserve cognition in schizophrenia?2019
- Author(s)
  Manabu Kubota
- Organizer
  14th World Congress of Biological Psychiatry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17101
[Presentation] Tau accumulation and metabotropic glutamate receptor subtype 5 binding in patients with frontotemporal lobar degeneration: A PET study.2019
- Author(s)
  Manabu Kubota et al.
- Organizer
  6th Congress of Asian College of Neuropsychopharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17101
[Presentation] 統合失調症の脳構造および分子神経基盤に関する統合的画像研究2018
- Author(s)
  久保田学
- Organizer
  第 40 回日本生物学的精神医学会
- Data Source
  KAKENHI-PROJECT-16K19790
[Presentation] 前頭側頭葉変性症における脳内タウ蓄積および代謝型グルタミン酸受容体５型の変化に関するPET研究2018
- Author(s)
  久保田学、島田斉、高畑圭輔、互健二、関千江、佐野康徳、山本保天、高堂裕平、篠遠仁、本井ゆみ子、鈴木寿臣、女屋光基、河村和紀、張明栄、須原哲也、樋口真人
- Organizer
  第 28 回日本臨床精神神経薬理学会・第48回日本神経精神薬理学会合同年会
- Data Source
  KAKENHI-PROJECT-16K19790
[Presentation] Alterations of central metabotropic glutamate receptor 5 binding and glutamate concentrations by food intake2018
- Author(s)
  Kubota M, Kimura Y, Ichise M, Seki C, Shimada H, Shinotoh H, Takahata K, Kitamura S, Moriguchi S, Ishii T, Tagai K, Takado Y, Sano H, Obata T, Tokunaga M, Maeda J, Zhang MR, Suhara T, Higuchi M
- Organizer
  The 31st CINP World Congress of Neuropsychopharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19790
[Presentation] Binding of a metabotropic glutamate receptor subtype 5 radioligand, (E)-[11C]ABP688, in human brains assessed by test-retest PET scans2017
- Author(s)
  Kubota M, Kimura Y, Ichise M, Seki C, Takahata K, Kitamura S, Moriguchi S, Ishii T, Zhang MR, Higuchi M, Suhara T
- Organizer
  28th Symposium on Cerebral Blood Flow, Metabolism and Function 13th Conference on Quantification of Brain Function with PET
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19790
[Presentation] Total and high-affinity-state dopamine D2 receptors in the striatum of antipsychotic-free patients with schizophrenia: a PET study with [11C]raclopride and [11C]MNPA2017
- Author(s)
  Kubota M, Nagashima T, Takano H, Kodaka F, Fujiwara H, Takahata K, Moriguchi S, Kimura Y, Higuchi M, Okubo Y, Takahashi H, Suhara T
- Organizer
  13th World Congress of Biological Psychiatry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19790
[Presentation] 統合失調症の脳構造および分子神経基盤に関する統合的画像研究2017
- Author(s)
  久保田学
- Organizer
  第39回日本生物学的精神医学会
- Data Source
  KAKENHI-PROJECT-16K19790

1. 高畑圭輔 (20645311)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
2. 山内浩 (40360812)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 上田敬太 (60573079)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 大石直也 (40526878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 麻生俊彦 (50397543)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 生方志浦 (40738960)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 大塚貞男 (00816986)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 伏見育崇 (90639014)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SHIMADA Hitoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 樋口真人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 小野麻衣子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 垂水良介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kubota Manabu 久保田 学

Research Projects

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Co-Researchers

統合失調症と自閉スペクトラム症への社会認知トレーニングの効果増強：神経基盤の解明

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タウ・アミロイドPETおよび7テスラMRI/MRSによる中高年期精神疾患の層別化Principal Investigator

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Investigation about underpinning neural mechanisms of sequelae and brain atrophy after brain injury

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Classification of schizophrenia-related disorders by multimodal neuroimaging assessments of PDE10APrincipal Investigator

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Associations between central glutamatergic neurotransmission and cognition in schizophrenia using novel PET ligands related to AMPAPrincipal Investigator

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脳内ドーパミン神経伝達機能と白質線維統合性の関連についての研究Principal Investigator

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[Book] 『統合失調症治療の新たなストラテジー 第２版』「Part 2-4. 画像からみた統合失調症の脳機能」2021

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[Book] 日本生物学的精神医学会誌 2018. Vol.29, No.4. Mini Review『統合失調症の脳構造および分子神経基盤』2018

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[Journal Article] In vivo PET classification of tau pathologies in patients with frontotemporal dementia2024

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[Journal Article] Two pathways differentially linking tau depositions, oxidative stress, and neuronal loss to apathetic phenotypes in progressive supranuclear palsy2023

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[Journal Article] PET-based classification of corticobasal syndrome.2022

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[Journal Article] Positron Emission Tomography Assessments of Phosphodiesterase 10A in Patients With Schizophrenia2022

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[Journal Article] High-Contrast In Vivo Imaging of Tau Pathologies in Alzheimer’s and Non-Alzheimer’s Disease Tauopathies2021

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[Journal Article] A first-in-human study of 11C-MTP38, a novel PET ligand for phosphodiesterase 72021

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[Journal Article] Relationship between regional gray matter volumes and dopamine D2 receptor and transporter in living human brains2021

Kubota Manabu 久保田学

[Book] 『統合失調症治療の新たなストラテジー第２版』「Part 2-4. 画像からみた統合失調症の脳機能」2021