YAMASHITA SEISUKE 山下征輔

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Yamashita Seisuke 山下征輔

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Researcher Number	30769576
Other IDs
Affiliation (Current)	2025: 東京大学, 大学院新領域創成科学研究科, 助教
Affiliation (based on the past Project Information) *help	2019 – 2023: 東京大学, 大学院新領域創成科学研究科, 助教 2016 – 2018: 東京大学, 大学院新領域創成科学研究科, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 43020:Structural biochemistry-related / Structural biochemistry
Keywords	Principal Investigator U6 snRNA / TUT1 / X線結晶構造解析 / ヌクレオチド転移酵素 / ADPリボシル化 / 構造生物学 / ADPリボシル化酵素 / RNA / 生体分子 / Ｘ線結晶構造解析 … More / Star-PAP / RNA修飾 / ヌクレオチド付加 / TUTase Less

ADPリボシル化酵素PARP7による自然免疫制御の分子構造基盤Principal Investigator
- Principal Investigator
  
  山下征輔
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  The University of Tokyo
Structural basis for the RNA poly-uridylylation by human TUT1Principal Investigator
- Principal Investigator
  
  YAMASHITA Seisuke
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  The University of Tokyo
Structural analysis of the poly A polymerase activated by oxidative stressPrincipal Investigator
- Principal Investigator
  
  Yamashita Seisuke
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  The University of Tokyo

All 2023 2022 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Mechanism of tRNA recognition by heterotetrameric glycyl-tRNA synthetase from lactic acid bacteria2023
- Author(s)
  Nagato Yasuha、Yamashita Seisuke、Ohashi Azusa、Furukawa Haruyuki、Takai Kazuyuki、Tomita Kozo、Tomikawa Chie
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 174 Issue: 3 Pages: 291-303
- DOI
  10.1093/jb/mvad043
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06109, KAKENHI-PROJECT-23H00368
[Journal Article] Structure of the<i>Caenorhabditis elegans</i>m6A methyltransferase METT10 that regulates SAM homeostasis2023
- Author(s)
  Ju Jue、Aoyama Tomohiko、Yashiro Yuka、Yamashita Seisuke、Kuroyanagi Hidehito、Tomita Kozo
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 51 Issue: 5 Pages: 2434-2446
- DOI
  10.1093/nar/gkad081
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06109, KAKENHI-PROJECT-22K15055, KAKENHI-PUBLICLY-20H04839, KAKENHI-PROJECT-20H03181
[Journal Article] Mechanism of U6 snRNA oligouridylation by human TUT12023
- Author(s)
  Yamashita Seisuke、Tomita Kozo
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1
- DOI
  10.1038/s41467-023-40420-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06109, KAKENHI-PROJECT-23H00368
[Journal Article] Reversible RNA phosphorylation stabilizes tRNA for cellular thermotolerance2022
- Author(s)
  Takayuki Ohira, Keiichi Minowa, Kei Sugiyama, Seisuke Yamashita, Yuriko Sakaguchi, Kenjyo Miyauchi, Ryo Noguchi, Akira Kaneko, Izumi Orita, Toshiaki Fukui, Kozo Tomita,Tsutomu Suzuki
- Journal Title
  
  Nature
  
  Volume: - Issue: 7909 Pages: 372-379
- DOI
  10.1038/s41586-022-04677-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H03980, KAKENHI-PROJECT-22K06109, KAKENHI-PROJECT-18H05272
[Journal Article] Mechanistic insights into m6A modification of U6 snRNA by human METTL162020
- Author(s)
  Aoyama Tomohiko、Yamashita Seisuke、Tomita Kozo
- Journal Title
  
  Nucleic Acids Research
  
  Volume: - Issue: 9 Pages: 5157-5168
- DOI
  10.1093/nar/gkaa227
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16053, KAKENHI-PROJECT-18J23142, KAKENHI-PROJECT-18H03980
[Journal Article] Crystal structure of human cytoplasmic tRNAHis-specific 5′-monomethylphosphate capping enzyme2020
- Author(s)
  Liu Yining、Martinez Anna、Yamashita Seisuke、Tomita Kozo
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 48 Issue: 3 Pages: 1572-1582
- DOI
  10.1093/nar/gkz1216
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16053, KAKENHI-PROJECT-18H03980
[Journal Article] Crystal structure of the enterohemorrhagic Escherichia coli AtaT-AtaR toxin-antitoxin complex.2019
- Author(s)
  Yashiro Y, Yamashita S, Tomita K.
- Journal Title
  
  Structure
  
  Volume: 27 Issue: 3 Pages: 476-484
- DOI
  10.1016/j.str.2018.11.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03980, KAKENHI-PROJECT-16K18510
[Journal Article] Crystal structure of the Lin28-interacting module of human terminal uridylyltransferase that regulates let-7 expression2019
- Author(s)
  Yamashita Seisuke、Nagaike Takashi、Tomita Kozo
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 1960-1960
- DOI
  10.1038/s41467-019-09966-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K18510, KAKENHI-PROJECT-18H03980
[Journal Article] Acetate-dependent tRNA acetylation required for decoding fidelity in protein synthesis2018
- Author(s)
  Taniguchi T, Miyauchi K, Sakaguchi Y, Yamashita S, Soma A, Tomita K, Suzuki T
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 14 Issue: 11 Pages: 1010-1020
- DOI
  10.1038/s41589-018-0119-z
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-26113002, KAKENHI-PLANNED-26113003, KAKENHI-PROJECT-18H03980, KAKENHI-PROJECT-16K18510, KAKENHI-PROJECT-18H05272
[Journal Article] Human BCDIN3D Monomethylates Cytoplasmic Histidine Transfer RNA.2017
- Author(s)
  Martinez A, Yamashita S, Nagaike T, Sakaguchi Y, Suzuki T, Tomita K
- Journal Title
  
  Nucleic Acids Res
  
  Volume: - Pages: 5423-5436
- DOI
  10.1093/nar/gkx051
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-26113002, KAKENHI-PROJECT-26251009, KAKENHI-PROJECT-16K18510, KAKENHI-PROJECT-26220205, KAKENHI-PLANNED-26113003
[Journal Article] Crystal structures of U6 snRNA-specific terminal uridylyltransferase2017
- Author(s)
  Yamashita Seisuke、Takagi Yuko、Nagaike Takashi、Tomita Kozo
- Journal Title
  
  Nature Communications
  
  Volume: 8 Issue: 1 Pages: 15788-15788
- DOI
  10.1038/ncomms15788
- Data Source
  KAKENHI-PROJECT-16K18510
[Presentation] Structural basis for the U6 snRNA uridylylation by human TUT12022
- Author(s)
  Seisuke Yamashita, Kozo Tomita
- Organizer
  第23回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-22K06109
[Presentation] Crystal structure of the Lin28-interacting module of human terminal uridylyltransferase that regulates let-7 expression2019
- Author(s)
  Seisuke Yamashita, Kozo Tomita
- Organizer
  第21回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-19K16053
[Presentation] Crystal structures of U6 snRNA-specific terminal uridylyltransferase2017
- Author(s)
  Seisuke Yamashita, Kozo Tomita
- Organizer
  第43回内藤コンファレンス
- Data Source
  KAKENHI-PROJECT-16K18510
[Presentation] Mechanism of 3'-matured tRNA discrimination from 3'-immature tRNA by class-II CCA-adding enzyme2016
- Author(s)
  Seisuke Yamashita
- Organizer
  The 26th tRNA conference
- Place of Presentation
  韓国、済州
- Year and Date
  2016-09-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18510

1. 富田耕造

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results

YAMASHITA SEISUKE 山下 征輔

Yamashita Seisuke 山下 征輔

Research Projects

Research Products

Co-Researchers

ADPリボシル化酵素PARP7による自然免疫制御の分子構造基盤Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structural basis for the RNA poly-uridylylation by human TUT1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structural analysis of the poly A polymerase activated by oxidative stressPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Mechanism of tRNA recognition by heterotetrameric glycyl-tRNA synthetase from lactic acid bacteria2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structure of the<i>Caenorhabditis elegans</i>m6A methyltransferase METT10 that regulates SAM homeostasis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mechanism of U6 snRNA oligouridylation by human TUT12023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reversible RNA phosphorylation stabilizes tRNA for cellular thermotolerance2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mechanistic insights into m6A modification of U6 snRNA by human METTL162020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Crystal structure of human cytoplasmic tRNAHis-specific 5′-monomethylphosphate capping enzyme2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Crystal structure of the enterohemorrhagic Escherichia coli AtaT-AtaR toxin-antitoxin complex.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Crystal structure of the Lin28-interacting module of human terminal uridylyltransferase that regulates let-7 expression2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Acetate-dependent tRNA acetylation required for decoding fidelity in protein synthesis2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Human BCDIN3D Monomethylates Cytoplasmic Histidine Transfer RNA.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Crystal structures of U6 snRNA-specific terminal uridylyltransferase2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] Structural basis for the U6 snRNA uridylylation by human TUT12022

Author(s)

YAMASHITA SEISUKE 山下征輔

Yamashita Seisuke 山下征輔