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Masuda Kenta  増田 健太

ORCIDConnect your ORCID iD *help
… Alternative Names

増田 健太  マスダ ケンタ

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Researcher Number 30773460
Other IDs
Affiliation (Current) 2025: 慶應義塾大学, 医学部(信濃町), 講師
Affiliation (based on the past Project Information) *help 2020 – 2023: 慶應義塾大学, 医学部(信濃町), 助教
2016: 慶應義塾大学, 医学部, 共同研究員
Review Section/Research Field
Principal Investigator
Basic Section 50010:Tumor biology-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology
Except Principal Investigator
Basic Section 50010:Tumor biology-related
Keywords
Principal Investigator
卵巣癌 / オルガノイド / 微小残存病変 / 治療抵抗性 / 卵巣がんモデルマウス / 空間的遺伝子発現解析 / 免疫微小環境 / 卵巣がん / 癌予防薬 / シングルセル解析 … More / 卵巣癌オルガノイド / 卵管オルガノイド / RNA sequence / マウスモデル / 動物モデル / 代謝 / 脂質代謝 / 活性酸素 … More
Except Principal Investigator
微小残存病変 / MYC / 卵巣がん / リンパ腫 / MYC Less
  • Research Projects

    (5 results)
  • Research Products

    (34 results)
  • Co-Researchers

    (10 People)
  •  卵管オルガノドを駆使した卵巣癌早期発見マーカー、癌予防薬の同定Principal Investigator

    • Principal Investigator
      増田 健太
    • Project Period (FY)
      2023 – 2028
    • Research Category
      Fund for the Promotion of Joint International Research (International Collaborative Research)
    • Review Section
      Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Keio University
  •  卵巣癌の微小残存病変における腫瘍免疫微小環境の解明Principal Investigator

    • Principal Investigator
      増田 健太
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Keio University
  •  Elucidation of the molecular basis of MYC-driven cancers and development of therapeutic strategies

    • Principal Investigator
      杉原 英志
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Fujita Health University
  •  Analysis of minimal residual disease in ovarian cancerPrincipal Investigator

    • Principal Investigator
      Masuda Kenta
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Keio University
  •  卵巣癌の治療抵抗性に関わる代謝特性の解明と新規治療標的の同定Principal Investigator

    • Principal Investigator
      増田 健太
    • Project Period (FY)
      2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Keio University

All 2023 2022 2021

All Journal Article Presentation Book

  • [Book] Practical Guide to Hereditary Breast and Ovarian Cancer /Serous Tubal Intraepithelial Carcinoma (STIC) and Precancerous Lesions in Risk-Reducing Salpingo-oophorectomy (RRSO) Specimens2023

    • Author(s)
      Masuda K,Aoki D
    • Total Pages
      154
    • Publisher
      Springer Nature Singapore Pte Ltd.
    • Data Source
      KAKENHI-PROJECT-23K06640
  • [Book] Practical Guide to Hereditary Breast and Ovarian Cancer /Serous Tubal Intraepithelial Carcinoma (STIC) and Precancerous Lesions in Risk-Reducing Salpingo-oophorectomy (RRSO) Specimens2023

    • Author(s)
      Masuda K,Aoki D
    • Total Pages
      154
    • Publisher
      Springer Nature Singapore Pte Ltd.
    • Data Source
      KAKENHI-PROJECT-23KK0159
  • [Book] Hereditary Ovarian Cancer / Hereditary Breast and Ovarian Cancer:Molecular Mechanism and Clinical Practice2021

    • Author(s)
      Masuda K,Satake M,Aoki D
    • Total Pages
      332
    • Publisher
      Springer
    • ISBN
      9789811645211
    • Data Source
      KAKENHI-PROJECT-20K18174
  • [Journal Article] <i>BRCA1/2</i> reversion mutations in a pan‐cancer cohort2023

    • Author(s)
      Nakamura K、Hayashi H、Kawano R、Ishikawa M、Aimono E、Mizuno T、Kuroda H、Kojima Y、Niikura N、Kawanishi A、Takeshita K、Suzuki S、Ueno S、Okuwaki K、Sasaki J、Yamaguchi M、Masuda K、 Chiyoda T、Yamagami W、Okada C、Nohara S、Tanishima S、Nishihara H
    • Journal Title

      Cancer Science

      Volume: 115 Issue: 2 Pages: 635-647

    • DOI

      10.1111/cas.16033

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23KK0159, KAKENHI-PROJECT-23K06640, KAKENHI-PROJECT-23K21475, KAKENHI-PROJECT-23K27824
  • [Journal Article] Evaluation of the one-step nucleic acid amplification assay for detecting lymph node metastasis in patients with cervical and endometrial cancer: A multicenter prospective study2023

    • Author(s)
      Togami Shinichi、Tanimoto Akihide、Yanazume Shintaro、Tokunaga Hideki、Nagai Tomoyuki、Watanabe Mika、Yahata Hideaki、Asanoma Kazuo、et al.
    • Journal Title

      Gynecologic Oncology

      Volume: 170 Pages: 70-76

    • DOI

      10.1016/j.ygyno.2022.12.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K09519, KAKENHI-PROJECT-23KK0159, KAKENHI-PROJECT-23K06640
  • [Journal Article] <i>TP53</i> variants in p53 signatures and the clonality of STICs in RRSO samples2022

    • Author(s)
      Akahane Tomoko、Masuda Kenta、Hirasawa Akira、Kobayashi Yusuke、Ueki Arisa、Kawaida Miho、Misu Kumiko、Nakamura Kohei、Nagai Shimpei、Chiyoda Tatsuyuki、Yamagami Wataru、Hayashi Shigenori、Kataoka Fumio、Banno Kouji、Sugano Kokichi、Okita Hajime、Kosaki Kenjiro、Nishihara Hiroshi、Aoki Daisuke
    • Journal Title

      Journal of Gynecologic Oncology

      Volume: 33 Issue: 4

    • DOI

      10.3802/jgo.2022.33.e50

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K16881, KAKENHI-PROJECT-20K18174, KAKENHI-PROJECT-23K21475
  • [Journal Article] MEK inhibition suppresses metastatic progression of <i>KRAS</i> ‐mutated gastric cancer2022

    • Author(s)
      Yamasaki Juntaro、Hirata Yuki、Otsuki Yuji、Suina Kentaro、Saito Yoshiyuki、Masuda Kenta、Okazaki Shogo、Ishimoto Takatsugu、Saya Hideyuki、Nagano Osamu
    • Journal Title

      Cancer Science

      Volume: 113 Issue: 3 Pages: 916-925

    • DOI

      10.1111/cas.15244

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K16315, KAKENHI-PROJECT-21H02766, KAKENHI-PROJECT-21K19416, KAKENHI-PROJECT-21K19417, KAKENHI-PROJECT-20K18174, KAKENHI-PROJECT-22K20836, KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-21K19535
  • [Journal Article] SIK2 inhibition enhances PARP inhibitor activity synergistically in ovarian and triple-negative breast cancers2022

    • Author(s)
      Lu Z、Mao W、Yang H、Santiago-O’Farrill JM.、Rask PJ.、Mondal J、Chen H、Ivan C、Liu X、Liu CG、Xi Y、Masuda K、Carrami EM.、Chen M、Tang Y、Pang L、Lakomy DS、Calin GA、Liang H、Ahmed AA、Vankayalapati H、Bast RC
    • Journal Title

      Journal of Clinical Investigation

      Volume: 132 Issue: 11

    • DOI

      10.1172/jci146471

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K18174
  • [Journal Article] Current status of hereditary breast and ovarian cancer practice among gynecologic oncologists in Japan: a nationwide survey by the Japan Society of Gynecologic Oncology (JSGO)2022

    • Author(s)
      Kobayashi Y, Masuda K, Hiraswa A, Takehara K, Tsuda H, Watanabe Y, Oda K, Nagase S, Mandai M, Okamoto A, Yaegashi N, Mikami M, Enomoto T, Aoki D, Katabuchi H; Working Group on Clinical Practice for Cancer Genomic Medicine and HBOC, Japan Society of Gynecologic Oncology.
    • Journal Title

      J Gynecol Oncol.

      Volume: 33 Issue: 5

    • DOI

      10.3802/jgo.2022.33.e61

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K09673, KAKENHI-PROJECT-20H03821, KAKENHI-PROJECT-20H03828, KAKENHI-PROJECT-20K18174, KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-21H03074
  • [Journal Article] Presence of spontaneous epithelial-mesenchymal plasticity in esophageal cancer2022

    • Author(s)
      Tsuchihashi Kenji、Hirata Yuki、Yamasaki Juntaro、Suina Kentaro、Tanoue Kenro、Yae Toshifumi、Masuda Kenta、Baba Eishi、Akashi Koichi、Kitagawa Yuko、Saya Hideyuki、Nagano Osamu
    • Journal Title

      Biochemistry and Biophysics Reports

      Volume: 30 Pages: 101246-101246

    • DOI

      10.1016/j.bbrep.2022.101246

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H00518, KAKENHI-PROJECT-21H02766, KAKENHI-PROJECT-20K07638, KAKENHI-PROJECT-21K19417, KAKENHI-PROJECT-22K20836, KAKENHI-PROJECT-20K18174
  • [Journal Article] Adipocyte-like signature in ovarian cancer minimal residual disease identifies metabolic vulnerabilities of tumor-initiating cells2021

    • Author(s)
      Artibani M, Masuda K, Hu Z, Rauher PC, Mallett G, Wietek N, Morotti M, Chong K, KaramiNejadRanjbar M, Zois CE, Dhar S, El-Sahhar S, Campo L, Blagden SP, Damato S, Pathiraja PN, Nicum S, Gleeson F, Laios A, Alsaadi A, Santana Gonzalez L, Motohara T, et al.
    • Journal Title

      JCI Insight.

      Volume: 6

    • DOI

      10.1172/jci.insight.147929

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09826, KAKENHI-PROJECT-20K18174
  • [Presentation] Development of a new ovarian cancer mouse model by engineering mouse fallopian tube epithelial organoids.2023

    • Author(s)
      永井晋平,増田健太,今枝慶蓉,田村友宏,千代田達幸,小林佑介,阪埜浩司,田中守,青木大輔
    • Organizer
      第75回日本産科婦人科学会学術講演会
    • Data Source
      KAKENHI-PROJECT-23K06640
  • [Presentation] がん遺伝子パネル検査の結果からPGPVが同定された婦人科悪性腫瘍症例に関する検討2023

    • Author(s)
      林 龍馬,増田健太,中村康平,千代田達幸,西尾 浩,小林佑介,岩田 卓,阪埜浩司,西原広史,山上 亘
    • Organizer
      第22回日本婦人科がん分子標的研究会
    • Data Source
      KAKENHI-PROJECT-23KK0159
  • [Presentation] 新規マウスモデルを用いた高異型度漿液性癌の予後不良に関連するバイオマーカーの同定2023

    • Author(s)
      今枝 慶蓉, 増田 健太, 永井 晋平, 田村 友宏, 杉原 英志, 山崎 淳太郎, 大槻 雄士, 信末 博行, 千代田 達幸, 小林 佑介, 阪埜 浩司, 青木 大輔, 山上 亘, 佐谷 秀行, 永野 修.
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K07179
  • [Presentation] Effects of TP53 variants and p53 dysfunction in premalignant lesions of fallopian tubes2023

    • Author(s)
      Masuda K,Nagai S,Tamura T,Imaeda K,Akahane T,Chiyoda T,Kobayashi Y,Banno K,Aoki D,Yamagami W
    • Organizer
      第65回日本婦人科腫瘍学会学術講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K06640
  • [Presentation] Identification of biomarkers associated to poor prognosis in high-grade serous carcinoma using novel mouse models2023

    • Author(s)
      今枝慶蓉,増田健太,永井晋平,田村友宏,杉原英志,山﨑淳太郎,大槻雄士,信末博行,千代田達幸,小林佑介,阪埜浩司,青木大輔,山上 亘,佐谷秀行,永野 修
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-23KK0159
  • [Presentation] 腫瘍別シンポジウム 乳癌・卵巣癌研究の最前線 遺伝子改変オルガノイドモデルとヒトサンプルを用いた化学療法後の卵巣癌残存腫瘍細胞の解析2023

    • Author(s)
      増田健太,阪埜浩司,青木大輔,山上 亘,佐谷秀行,永野 修
    • Organizer
      第82回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K06640
  • [Presentation] がん遺伝子パネル検査の結果からPGPVが同定された婦人科悪性腫瘍症例に関する検討2023

    • Author(s)
      林 龍馬,増田健太,中村康平,千代田達幸,西尾 浩,小林佑介,岩田 卓,阪埜浩司,西原広史,山上 亘
    • Organizer
      第22回日本婦人科がん分子標的研究会
    • Data Source
      KAKENHI-PROJECT-23K06640
  • [Presentation] 腫瘍別シンポジウム 乳癌・卵巣癌研究の最前線 遺伝子改変オルガノイドモデルとヒトサンプルを用いた化学療法後の卵巣癌残存腫瘍細胞の解析2023

    • Author(s)
      増田健太,阪埜浩司,青木大輔,山上 亘,佐谷秀行,永野 修
    • Organizer
      第82回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23KK0159
  • [Presentation] Effects of TP53 variants and p53 dysfunction in premalignant lesions of fallopian tubes2023

    • Author(s)
      Masuda K,Nagai S,Tamura T,Imaeda K,Akahane T,Chiyoda T,Kobayashi Y,Banno K,Aoki D,Yamagami W
    • Organizer
      第65回日本婦人科腫瘍学会学術講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23KK0159
  • [Presentation] Development of a new ovarian cancer mouse model by engineering mouse fallopian tube epithelial organoids.2023

    • Author(s)
      永井晋平,増田健太,今枝慶蓉,田村友宏,千代田達幸,小林佑介,阪埜浩司,田中守,青木大輔
    • Organizer
      第75回日本産科婦人科学会学術講演会
    • Data Source
      KAKENHI-PROJECT-23KK0159
  • [Presentation] Identification of biomarkers associated to poor prognosis in high-grade serous carcinoma using novel mouse models2023

    • Author(s)
      今枝慶蓉,増田健太,永井晋平,田村友宏,杉原英志,山﨑淳太郎,大槻雄士,信末博行,千代田達幸,小林佑介,阪埜浩司,青木大輔,山上 亘,佐谷秀行,永野 修
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K06640
  • [Presentation] 野澤記念受賞講演 難治性卵巣癌の完治を目的とした微小残存病変に対する新規治療法の開発2023

    • Author(s)
      増田健太
    • Organizer
      第65回日本婦人科腫瘍学会学術講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K06640
  • [Presentation] 野澤記念受賞講演 難治性卵巣癌の完治を目的とした微小残存病変に対する新規治療法の開発2023

    • Author(s)
      増田健太
    • Organizer
      第65回日本婦人科腫瘍学会学術講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23KK0159
  • [Presentation] Development of a new ovarian cancer mouse model by engineering mouse fallopian tube epithelial organoids2022

    • Author(s)
      Shimpei Nagai, Kenta Masuda,Tomohiro Tamura,Keiyo Imaeda,Eiji Sugihara,Juntaro Yamasaki,Yuji Otsuki,Hiroyuki Nobusue,Tatsuyuki Chiyoda,Yusuke Kobayashi,Kouji Banno,Daisuke Aoki,Hideyuki Saya,Osamu Nagano
    • Organizer
      第81回 日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K18174
  • [Presentation] p53 dysfunction hampers the differentiation and causes the precancerous potency in mouse fallopian tube organoids2022

    • Author(s)
      Shimpei Nagai, Kenta Masuda,Tomohiro Tamura,Tomoko Akahane,Tatsuyuki Chiyoda,Yusuke Kobayashi,Kouji Banno,Mamoru Tanaka,Daisuke Aoki
    • Organizer
      第74回 日本産科婦人科学会学術講演会
    • Data Source
      KAKENHI-PROJECT-20K18174
  • [Presentation] MEK inhibition suppresses metastatic progression of KRAS-mutated gastric cancer2022

    • Author(s)
      Juntaro Yamasaki,Yuji Otsuki,Kenta Masuda,Hideyuki Saya,Osamu Nagano
    • Organizer
      第81回 日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K18174
  • [Presentation] RNA sequencing analysis of ovarian cancer minimal residual disease revealed a metabolic signature that would lead to the development of a new therapeutic strategy2022

    • Author(s)
      Kenta Masuda,Ahmed Ashour Ahmed,Tomohiro Tamura,Shimpei Nagai,Yuya Nogami,Kosuke Tsuji,Yusuke Kobayashi,Kouji Banno,Mamoru Tanaka,Daisuke Aoki
    • Organizer
      第74回 日本産科婦人科学会学術講演会
    • Data Source
      KAKENHI-PROJECT-20K18174
  • [Presentation] 予後不良卵巣癌の克服を目指した卵巣癌モデルマウスの開発2022

    • Author(s)
      増田健太,永井晋平,田村友宏,今枝慶蓉,千代田達幸,小林佑介,阪埜浩司,佐谷秀行,永野修,青木大輔
    • Organizer
      第21回 日本婦人科がん分子標的研究会
    • Data Source
      KAKENHI-PROJECT-20K18174
  • [Presentation] p53 dysfunction hampers the differentiation of mouse fallopian tube organoids2021

    • Author(s)
      Nagai S,Masuda K,Tamura T,Otsuki Y,Suina K,Nobusue H,Akahane T,Chiyoda T,Kobayashi Y,Banno K,Aoki D,Saya H,Nagano O
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K18174
  • [Presentation] Investigating minimal residual disease and chemotherapy resistance in ovarian cancer2021

    • Author(s)
      Masuda K,Artibani M,Nagai S,Kobayashi Y,Banno K,Saya H,Aoki D,Ahmed AA
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K18174
  • [Presentation] Analysis using a mouse ovarian cancer organoid model reveals cancer heterogeneity and cancer stem-like cell properties2021

    • Author(s)
      Tamura T,Masuda K,Nagai S,Otsuki Y,Suina K,Nobusue H,Sampetrean O,Banno K,Aoki D,Saya H,Nagano O
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K18174
  • [Presentation] 卵巣漿液性癌細胞株において脂肪酸酸化阻害はオラパリブに対する感受性を増加させる2021

    • Author(s)
      増田 健太、Ahmed Ahmed、永井 晋平、小林 佑介、冨永 英一郎、阪埜 浩司、田中 守、青木 大輔
    • Organizer
      第73回日本産科婦人科学会
    • Data Source
      KAKENHI-PROJECT-20K18174
  • [Presentation] RRSO検体におけるp53 signatureとSTICの特性に関する検討2021

    • Author(s)
      赤羽 智子、増田 健太、平沢 晃、小林 佑介、永井 晋平、千代田 達幸、林 茂徳、片岡 史夫、冨永 英一郎、阪埜 浩司、田中 守、青木 大輔
    • Organizer
      第73回日本産科婦人科学会
    • Data Source
      KAKENHI-PROJECT-20K18174
  • 1.  杉原 英志 (50464996)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 2.  鈴木 絢子 (00770348)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  竹田 貴 (60897106)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  辻 浩介 (70528166)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  MOTOHARA Takeshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  KATABUCHI Hidetaka
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  植木 有紗
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  浅野間 和夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  岡崎 章悟
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  佐谷 秀行
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