MIYASAKA Yuki 宮坂勇輝

Researcher Number	30778098
Affiliation (Current)	2025: 名古屋大学, 医学系研究科, 助教
Affiliation (based on the past Project Information) *help	2016 – 2024: 名古屋大学, 医学系研究科, 助教 2017: 名古屋大学, 大学院医学系研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 42040:Laboratory animal science-related / Laboratory animal science Except Principal Investigator Laboratory animal science
Keywords	Principal Investigator ネズミマラリア原虫 / マウス / 赤血球 / 宿主遺伝子 / TXNIP / 遺伝子 / 脳マラリア / NCマウス / 体系的遺伝解析系 / CRISPR/Cas9 … More / 遺伝学 / CRISPR/Cas9システム / ゲノム編集 / ゲノム編集技術 / 膵島脆弱性 / 糖尿病感受性遺伝子 / ストレプトゾトシン … More Except Principal Investigator 難聴 / 肺腫瘍感受性遺伝子 / ウレタン誘発肺腫瘍 / コンジェニック系統 / コンソミック系統 / 体系的遺伝解析系 / マウス / 疾患モデルマウス / CRISPR/Cas9システム / RNA-seq / 内耳外有毛細胞 / 疾患モデル / 対立遺伝子発現量 / 遺伝子発現 / カドヘリン23 / コンソミックマウス / アレル発現量比較 / ゲノム編集 / 遺伝学 / 実験動物学 Less

マウスApeh遺伝子内の1塩基多型がネズミマラリア原虫の増殖を制御する分子機構の解明Principal Investigator
- Principal Investigator
  
  宮坂勇輝
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Nagoya University
マウスNC系統の特性を利用した脳マラリア発症に必須な遺伝的要因の特定Principal Investigator
- Principal Investigator
  
  宮坂勇輝
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Nagoya University
Identification and analysis of the susceptibility gene for streptozotocin-induced diabetes in mice using the genome editing technologyPrincipal Investigator
- Principal Investigator
  
  Miyasaka Yuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Nagoya University
Identification of genetic risk factors and phenotypic rescue of deaf mutant mice based on technological innovations of the forward genetics approach
- Principal Investigator
  
  KIKKAWA Yoshiaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Identification of functional genes in outer hair cells using an inducible depletion mouse model
- Principal Investigator
  
  MATSUOKA Kunie
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Systematic genetic analysis for urethane-induced lung cancer susceptibility loci in mice
- Principal Investigator
  
  Ohno Tamio
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Nagoya University

All 2024 2021 2020 2018 2017 2016 2015

All Journal Article Presentation Book

[Book] An Excursus into Hearing Loss2018
- Author(s)
  Yasuda SP, Miyasaka Y, Kikkawa Y
- Publisher
  InTech
- ISBN
  9781789232127
- Data Source
  KAKENHI-PROJECT-15H04291
[Book] Monographs in Human Genetics -Genetics of Deafness-2016
- Author(s)
  Kikkawa Y, Miyasaka Y.
- Total Pages
  13
- Publisher
  Karger Publishers
- Data Source
  KAKENHI-PROJECT-15H04291
[Journal Article] Congenic mapping and candidate gene analysis for streptozotocin-induced diabetes susceptibility locus on mouse chromosome 112018
- Author(s)
  Maegawa Tomoki、Miyasaka Yuki、Kobayashi Misato、Babaya Naru、Ikegami Hiroshi、Horio Fumihiko、Takahashi Masahide、Ohno Tamio
- Journal Title
  
  Mammalian Genome
  
  Volume: 29 Issue: 3-4 Pages: 273-280
- DOI
  10.1007/s00335-018-9742-y
- NAID
  120006517666
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K14975, KAKENHI-PROJECT-15K09404, KAKENHI-PROJECT-26430088, KAKENHI-PROJECT-18K08493, KAKENHI-PROJECT-18K08530
[Journal Article] A novel splice site mutation of myosin VI in mice leads to stereociliary fusion caused by disruption of actin networks in the apical region of inner ear hair cells2017
- Author(s)
  Seki Yuta、Miyasaka Yuki、Suzuki Sari、Wada Kenta、Yasuda Shumpei P.、Matsuoka Kunie、Ohshiba Yasuhiro、Endo Kentaro、Ishii Rie、Shitara Hiroshi、Kitajiri Shin-ichiro、Nakagata Naomi、Takebayashi Hirohide、Kikkawa Yoshiaki
- Journal Title
  
  PLOS ONE
  
  Volume: 12 Issue: 8 Pages: e0183477-e0183477
- DOI
  10.1371/journal.pone.0183477
- NAID
  120007099799
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293369, KAKENHI-PROJECT-16H04688, KAKENHI-PROJECT-15K06818, KAKENHI-PROJECT-15K18393
[Journal Article] Heterozygous mutation of Ush1g/Sans in mice causes early-onset progressive hearing loss, which is recovered by reconstituting the strain-specific mutation in Cdh232016
- Author(s)
  Miyasaka Y, Shitara H, Suzuki S, Yoshimoto S, Seki Y, Ohshiba Y, Okumura K, Taya C, Tokano H, Kitamura K, Takada T, Hibino H, Shiroishi T, Kominami R, Yonekawa H, Kikkawa Y
- Journal Title
  
  Hum. Mol. Genet.
  
  Volume: 印刷中 Issue: 10 Pages: 2045-2059
- DOI
  10.1093/hmg/ddw078
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-14J06119, KAKENHI-PROJECT-25430097, KAKENHI-PROJECT-25293058, KAKENHI-PROJECT-15H04291, KAKENHI-PROJECT-16H04688, KAKENHI-PROJECT-25290038, KAKENHI-PROJECT-15K18393
[Presentation] 実験的脳マラリア感受性を示す3系統のマウスに共通して関与する宿主遺伝子の解析2024
- Author(s)
  宮坂勇輝，大山海, 岩竹望未，大野民生
- Organizer
  第93回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-20K15698
[Presentation] E3ユビキチンリガーゼRNF123欠損はネズミマラリア原虫（Plasmodium yoelii 17XL）感染初期の血虫率を低下させる2021
- Author(s)
  宮坂勇輝、丹羽祥太、舛屋智美、石井玲佳、小林美里、堀尾文彦、大野民生
- Organizer
  第90回日本寄生虫学会・第32回日本臨床寄生虫学会合同大会
- Data Source
  KAKENHI-PROJECT-20K15698
[Presentation] マウスNSY系統のストレプトゾトシン誘発糖尿病感受性遺伝子の解析－Rad50遺伝子のミスセンス変異（p.G200V）について－2020
- Author(s)
  宮坂勇輝、前川智樹、名倉巧真、小林美里、馬場谷成、池上博司、堀尾文彦、大野民生
- Organizer
  第34回日本糖尿病・肥満動物学会
- Data Source
  KAKENHI-PROJECT-17K14975
[Presentation] 誘導型破壊マウスを用いた内耳外有毛細胞における機能遺伝子の同定2018
- Author(s)
  松岡邦枝，安田俊平，和田健太，宮坂勇輝，設楽浩志，多屋長治，吉川欣亮
- Organizer
  第65回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-15K06818
[Presentation] カドヘリン 23 の c.753 遺伝子型が異なる C57BL/6J マウス間の加齢に伴う聴力表現型の比較2017
- Author(s)
  鈴木沙理，宮坂勇輝，関優太，安田俊平，松岡邦枝，設楽浩志，吉川欣亮
- Organizer
  第64回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-15K06818
[Presentation] カドヘリン23のc.753遺伝子型が異なるC57BL/6Jマウス間の加齢に伴う聴力表現型の比較2017
- Author(s)
  鈴木沙理，宮坂勇輝，関優太，安田俊平，松岡邦枝，設楽浩志，吉川欣亮
- Organizer
  第64回日本実験動物学会総会
- Place of Presentation
  ビッグパレットふくしま（福島県郡山市）
- Year and Date
  2017-05-25
- Data Source
  KAKENHI-PROJECT-15K06818
[Presentation] カドヘリン23 のc.753 遺伝子型が異なるC57BL/6Jマウス間の加齢に伴う聴力表現型の比較2017
- Author(s)
  鈴木沙理，宮坂勇輝，関　優太，安田俊平，松岡邦枝，設楽浩志，吉川欣亮
- Organizer
  第64回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-15H04291
[Presentation] Ca2+結合タンパク質Oncomodulinは内耳外有毛細胞の維持に機能する2017
- Author(s)
  松岡邦枝，宮坂勇輝，和田健太，安田俊平，設楽浩志，多屋長治，吉川欣亮
- Organizer
  第64回日本実験動物学会総会
- Place of Presentation
  ビッグパレットふくしま（福島県郡山市）
- Year and Date
  2017-05-25
- Data Source
  KAKENHI-PROJECT-15K06818
[Presentation] Ca2+ 結合タンパク質 Oncomodulin は内耳外有毛細胞の維持に機能する2017
- Author(s)
  松岡邦枝，宮坂勇輝，和田健太，安田俊平，設楽浩志，多屋長治，吉川欣亮
- Organizer
  第64回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-15K06818
[Presentation] 近交系の聴力差の遺伝的要因を探る2017
- Author(s)
  吉川欣亮，宮坂勇輝，安田俊平，設楽浩志
- Organizer
  2017年度遺伝研研究会「マウスとラットで拓く新しい比較実験動物学」
- Invited
- Data Source
  KAKENHI-PROJECT-15H04291
[Presentation] Heterozygous mutation of Ush1g/Sans in mice causes early-onset progressive hearing loss, which is rescued by reconstituting the strain-specific mutation in Cdh232016
- Author(s)
  Kikkawa Y, Miyasaka Y, Shitara H, Suzuki S, Shiroishi T, Kominami R, Yonekawa H
- Organizer
  Inner Ear Biology Workshop 2016
- Place of Presentation
  Le Corum（Montpellier, France）
- Year and Date
  2016-09-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04291
[Presentation] 外有毛細胞特異的遺伝子Oncomodulinノックアウトマウスにおける聴覚障害2016
- Author(s)
  松岡邦枝，宮坂勇輝，和田健太，安田俊平，設楽浩志，山口碧，多屋長治，吉川欣亮
- Organizer
  第63回日本実験動物学会総会
- Place of Presentation
  ミューザ川崎シンフォニーホール（神奈川県川崎市）
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-15K06818
[Presentation] マウスの遺伝的背景に潜む聴覚表現型を修飾する1塩基置換2016
- Author(s)
  宮坂勇輝，設楽浩志，鈴木沙理，高田豊行，城石俊彦，木南　凌，米川博通，吉川欣亮
- Organizer
  日本遺伝学会第88回大会
- Place of Presentation
  日本大学国際関係学部（静岡県・三島市）
- Year and Date
  2016-09-07
- Invited
- Data Source
  KAKENHI-PROJECT-15H04291
[Presentation] Ush1gヘテロマウスの聴覚障害はCdh23の1塩基置換により回復する2016
- Author(s)
  宮坂勇輝，設楽浩志，鈴木沙理，関　優太，多屋長治，高田豊行，城石俊彦，木南　凌，米川博通，吉川欣亮
- Organizer
  第63回日本実験動物学会総会
- Place of Presentation
  ミューザ川崎シンフォニーホール（神奈川県・川崎市）
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-15H04291
[Presentation] 成熟内耳におけるLrrc30の高発現とマウス加齢性難聴抑制効果の関連2015
- Author(s)
  宮坂勇輝, 安田俊平, 城石俊彦, 木南凌, 吉川欣亮
- Organizer
  第29回モロシヌス研究会
- Place of Presentation
  かんぽの宿有馬（兵庫県・神戸市）
- Year and Date
  2015-07-03
- Data Source
  KAKENHI-PROJECT-15H04291
[Presentation] 内耳外有毛細胞選択的破壊マウスを用いた特異遺伝子の探索2015
- Author(s)
  松岡邦枝，安田俊平，宮坂勇輝，和田健太，設楽浩志，山口碧，多屋長治，吉川欣亮
- Organizer
  第62回日本実験動物学会総会
- Place of Presentation
  京都テルサ（京都府京都市）
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-15K06818
[Presentation] マウス成熟内耳におけるLrrc30の高発現と加齢性難聴抑制効果の関連を探る!2015
- Author(s)
  宮坂勇輝，安田俊平，関　優太，松岡邦枝，日比野浩，木南　凌，吉川欣亮
- Organizer
  第62回実験動物学会総会
- Place of Presentation
  京都テルサ（京都府・京都市）
- Year and Date
  2015-05-30
- Data Source
  KAKENHI-PROJECT-15H04291
[Presentation] マウス成熟内耳におけるLrrc30の高発現と加齢性難聴抑制効果の関連を探る！2015
- Author(s)
  宮坂勇輝，安田俊平，関優太，松岡邦枝，日比野浩，木南凌，吉川欣亮
- Organizer
  第62回日本実験動物学会総会
- Place of Presentation
  京都テルサ（京都府京都市）
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-15K06818

1. KIKKAWA Yoshiaki (20280787)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
2. SHITARA Hiroshi (90321885)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
3. SEKI Yuta (10615636)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. YASUDA Shumpei (50534012)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
5. MATSUOKA Kunie (40291158)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
6. WADA Kenta (20508113)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
7. Ohno Tamio (90293620)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TOYOKUNI Shinya (90252460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. UNNO Akihiro (50628592)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 高田豊行 (20356257)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. OBARA Yo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SUZUKI Sari

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
13. MAEGAWA Tomoki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KITAJIRI Shinichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MIYASAKA Yuki 宮坂 勇輝

Research Projects

Research Products

Co-Researchers

マウスApeh遺伝子内の1塩基多型がネズミマラリア原虫の増殖を制御する分子機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

マウスNC系統の特性を利用した脳マラリア発症に必須な遺伝的要因の特定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification and analysis of the susceptibility gene for streptozotocin-induced diabetes in mice using the genome editing technologyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of genetic risk factors and phenotypic rescue of deaf mutant mice based on technological innovations of the forward genetics approach

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of functional genes in outer hair cells using an inducible depletion mouse model

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Systematic genetic analysis for urethane-induced lung cancer susceptibility loci in mice

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] An Excursus into Hearing Loss2018

Author(s)

Publisher

ISBN

Data Source

[Book] Monographs in Human Genetics -Genetics of Deafness-2016

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Congenic mapping and candidate gene analysis for streptozotocin-induced diabetes susceptibility locus on mouse chromosome 112018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] A novel splice site mutation of myosin VI in mice leads to stereociliary fusion caused by disruption of actin networks in the apical region of inner ear hair cells2017

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Heterozygous mutation of Ush1g/Sans in mice causes early-onset progressive hearing loss, which is recovered by reconstituting the strain-specific mutation in Cdh232016

Author(s)

Journal Title

DOI

Data Source

[Presentation] 実験的脳マラリア感受性を示す3系統のマウスに共通して関与する宿主遺伝子の解析2024

Author(s)

Organizer

Data Source

[Presentation] E3ユビキチンリガーゼRNF123欠損は ネズミマラリア原虫（Plasmodium yoelii 17XL）感染初期の血虫率を低下させる2021

Author(s)

Organizer

Data Source

[Presentation] マウスNSY系統のストレプトゾトシン誘発糖尿病感受性遺伝子の解析－Rad50遺伝子のミスセンス変異（p.G200V）について－2020

Author(s)

Organizer

Data Source

[Presentation] 誘導型破壊マウスを用いた内耳外有毛細胞における機能遺伝子の同定2018

MIYASAKA Yuki 宮坂勇輝

[Presentation] E3ユビキチンリガーゼRNF123欠損はネズミマラリア原虫（Plasmodium yoelii 17XL）感染初期の血虫率を低下させる2021