Onoguchi Rena 小野口玲菜

… Alternative Names

水谷玲菜

水谷玲菜ミズタニレナ

Less

Researcher Number	30780697
Other IDs
Affiliation (Current)	2025: 東京大学, アイソトープ総合センター, 助教
Affiliation (based on the past Project Information) *help	2016 – 2024: 東京大学, アイソトープ総合センター, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Transformative Research Areas, Section (III) / Biological pharmacy Except Principal Investigator Medium-sized Section 47:Pharmaceutical sciences and related fields / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
Keywords	Principal Investigator 熱ストレス応答 / 核内構造体 / 非コードRNA / 長鎖非コードRNA / 熱ストレス / 長鎖ノンコーディングRNA / ストレス応答 / ノンコーディングRNA Except Principal Investigator RNA / 核 … More / RNP / ストレス / 免疫 / 感染 / ノンコーディングRNA / 自然免疫 / サルモネラ Less

非ドメイン型バイオポリマーによる熱ストレス応答機構の解明Principal Investigator
- Principal Investigator
  
  小野口玲菜
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  The University of Tokyo
局所的なRNAの量的制御による熱応答性核内構造体の形成維持機構と生理的意義の解析Principal Investigator
- Principal Investigator
  
  小野口玲菜
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  The University of Tokyo
Study of novel stress response mechanism in human cells
- Principal Investigator
  
  秋光信佳
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  The University of Tokyo
Identification of functional domain of MALAT1 lncRNA in heat shock responsePrincipal Investigator
- Principal Investigator
  
  Onoguchi Rena
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  The University of Tokyo
Functional analysis of lncRNAs regulating immune response
- Principal Investigator
  
  Nobuyoshi Akimitsu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  The University of Tokyo
Analysis of heat-response gene regulation through norvel nuclear body by containing the noncoding RNAPrincipal Investigator
- Principal Investigator
  
  Onoguchi-Mizutani Rena
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  The University of Tokyo
Identification of the components of heat-responsible novel nuclear body containing MALAT1, a long noncoding RNAPrincipal Investigator
- Principal Investigator
  
  Onoguchi Rena
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo

All 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Techniques for Analyzing Genome-wide Expression of Non-coding RNA2023
- Author(s)
  Rena Onoguchi-Mizutani, Kenzui Taniue, Kentaro Kawata, Toshimichi Yamada, Nobuyoshi Akimitsu
- Journal Title
  
  Handbook of Epigenetics
  
  Volume: － Pages: 163-184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06578
[Journal Article] Long noncoding RNA and phase separation in cellular stress response2022
- Author(s)
  Onoguchi-Mizutani Rena、Akimitsu Nobuyoshi
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 171 Issue: 3 Pages: 269-276
- DOI
  10.1093/jb/mvab156
- Data Source
  KAKENHI-PROJECT-18K14899, KAKENHI-PROJECT-20K15988, KAKENHI-PROJECT-21H04792, KAKENHI-PUBLICLY-21H00243
[Journal Article] Identification of heat-inducible long noncoding RNA MALAT1-containing novel nuclear (HiNoCo) body2021
- Author(s)
  Rena Onoguchi-Mizutani , Yoshitaka Kirikae , Yoko Ogura , Tony Gutschner , Sven Diederichs , Nobuyoshi Akimitsu
- Journal Title
  
  The journal of Cell Science
  
  Volume: -
- Data Source
  KAKENHI-PROJECT-20K15988
[Journal Article] Identification of heat-inducible long noncoding RNA MALAT1 -containing novel nuclear (HiNoCo) body2021
- Author(s)
  Rena Onoguchi-Mizutani, Yoshitaka Kirikae, Yoko Ogura, Tony Gutschner, Sven Diederichs, Nobuyoshi Akimitsu
- Journal Title
  
  The journal of Cell Science
  
  Volume: -
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14899
[Journal Article] hnRNPH1-MTR4 complex-mediated regulation of <i>NEAT1v2</i> stability is critical for <i>IL8</i> expression2021
- Author(s)
  Tanu Tanzina、Taniue Kenzui、Imamura Katsutoshi、Onoguchi-Mizutani Rena、Han Han、Jensen Torben Heick、Akimitsu Nobuyoshi
- Journal Title
  
  RNA Biology
  
  Volume: 18 Issue: sup1 Pages: 537-547
- DOI
  10.1080/15476286.2021.1971439
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KT0016, KAKENHI-PROJECT-18H02570, KAKENHI-PROJECT-21K19402, KAKENHI-PROJECT-20K15988, KAKENHI-PROJECT-17KK0163, KAKENHI-PUBLICLY-20H04838, KAKENHI-PROJECT-21H02758
[Journal Article] A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cells2021
- Author(s)
  Yamamoto Keita、Goyama Susumu、Asada Shuhei、Fujino Takeshi、Yonezawa Taishi、Sato Naru、Takeda Reina、Tsuchiya Akiho、Fukuyama Tomofusa、Tanaka Yosuke、Yokoyama Akihiko、Toya Hikaru、Kon Ayana、Nannya Yasuhito、Onoguchi-Mizutani Rena、Nakagawa Shinichi、Hirose Tetsuro、Ogawa Seishi、Akimitsu Nobuyoshi、Kitamura Toshio
- Journal Title
  
  Cell Reports
  
  Volume: 36 Issue: 8 Pages: 109576-109576
- DOI
  10.1016/j.celrep.2021.109576
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H05377, KAKENHI-PUBLICLY-21H00274, KAKENHI-PLANNED-21H05276, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-20H00537, KAKENHI-PROJECT-17H03604, KAKENHI-PROJECT-19H03685, KAKENHI-PROJECT-19H03694, KAKENHI-PROJECT-19J01570, KAKENHI-PROJECT-20K15988, KAKENHI-PLANNED-21H05274
[Journal Article] Identification of novel heat shock-induced long non-coding RNA in human cells2020
- Author(s)
  Onoguchi-Mizutani Rena、Kishi Yoshihiro、Ogura Yoko、Nishimura Yuuki、Imamachi Naoto、Suzuki Yutaka、Miyazaki Satoru、Akimitsu Nobuyoshi
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: - Issue: 4 Pages: 497-505
- DOI
  10.1093/jb/mvaa126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K14899, KAKENHI-PROJECT-20K15988
[Journal Article] Identification of Minimal p53 Promoter Region Regulated by MALAT1 in Human Lung Adenocarcinoma Cells.2018
- Author(s)
  Tano K, Onoguchi-Mizutani R, Yeasmin F, Uchiumi F, Suzuki Y, Yada T, Akimitsu N
- Journal Title
  
  frontiers in Genetics
  
  Volume: なし Pages: 208-208
- DOI
  10.3389/fgene.2017.00208
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06743, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-18K14899
[Journal Article] Diminished nuclear RNA decay upon Salmonella infection upregulates antibacterial noncoding RNAs2018
- Author(s)
  Imamura Katsutoshi、Takaya Akiko、Ishida Yo‐ichi、Fukuoka Yayoi、Taya Toshiki、Nakaki Ryo、Kakeda Miho、Imamachi Naoto、Sato Aiko、Yamada Toshimichi、Onoguchi‐Mizutani Rena、Akizuki Gen、Tanu Tanzina、Tao Kazuyuki、Miyao Sotaro、Suzuki Yutaka、Nagahama Masami、Yamamoto Tomoko、Jensen Torben Heick、Akimitsu Nobuyoshi
- Journal Title
  
  The EMBO Journal
  
  Volume: 37 Issue: 13
- DOI
  10.15252/embj.201797723
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06640, KAKENHI-PROJECT-18K07102, KAKENHI-PROJECT-18K14899, KAKENHI-PROJECT-17J11266, KAKENHI-PROJECT-16H06279
[Journal Article] 5'-Bromouridine IP Chase (BRIC)-Seq to Determine RNA Half-Lives.2018
- Author(s)
  Yamada T, Imamachi N, Onoguchi-Mizutani R, Imamura K, Suzuki Y, Akimitsu N.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 1720 Pages: 1-13
- DOI
  10.1007/978-1-4939-7540-2_1
- ISBN
  9781493975396, 9781493975402
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06743, KAKENHI-PROJECT-15J04318, KAKENHI-PROJECT-17J11266, KAKENHI-PROJECT-15K07923
[Presentation] ノンコーディングRNAが形成する新規核内構造体による熱ストレス応答の研究2023
- Author(s)
  小野口玲菜, 小野口真広, 浜田道昭, 秋光信佳
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K06578
[Presentation] Heat shock stress response through HiNoCo-body, a novel noncoding RNA containing nuclear body2022
- Author(s)
  Rena Onoguchi-Mizutani, Takeshi Kawamura, Nobuyoshi Akimitsu.
- Organizer
  Cold Spring Harbor Asia “RNA Biology”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06578
[Presentation] 非コードRNAを含有する熱ストレス応答性の新規核内構造体, HiNoCo-bodyの同定2021
- Author(s)
  小野口玲菜、秋光信佳
- Organizer
  日本薬学会第141年会（広島）
- Data Source
  KAKENHI-PROJECT-20K15988
[Presentation] 非コードRNAを含有する熱ストレス応答性の新規核内構造体, HiNoCo-bodyの同定2021
- Author(s)
  小野口玲菜、秋光信佳
- Organizer
  日本薬学会第141年会（広島）
- Data Source
  KAKENHI-PROJECT-18K14899
[Presentation] Characterization of heat-responsible novel nuclear body containing MALAT1, a long noncoding RNA2019
- Author(s)
  Rena Onoguchi-Mizutani, Takeshi Kawamura, Yutaka Suzuki, Nobuyoshi, Akimitsu.
- Organizer
  RNA Control & Regulation -84th Cold Spring Harbor Laboratory Symposium-
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14899
[Presentation] 長鎖非コードRNAを含有する新規核内構造体, HiNoCo-bodyを介した熱ショック応答機構の解析2018
- Author(s)
  小野口(水谷) 玲菜、鈴木穣、川村猛、秋光信佳
- Organizer
  第２０回日本RNA学会
- Data Source
  KAKENHI-PROJECT-18K14899
[Presentation] Characterization of heat-responsible novel nuclear body containing MALAT12018
- Author(s)
  Rena Onoguchi-Mizutani
- Organizer
  第25回Tokyo RNA Club
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14899
[Presentation] 長鎖非コードRNA, MALAT1を含有する新規核内構造体を介した熱ショック応答機構の解明2017
- Author(s)
  小野口(水谷)玲菜、　鈴木穣、　川村猛、秋光信佳
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-16H06743

1. Nobuyoshi Akimitsu (40294962)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. 垰和之 (00211996)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 高屋明子 (80334217)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 谷上賢瑞 (90648627)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 長浜正己

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 広瀬哲郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Onoguchi Rena 小野口 玲菜

水谷玲菜

水谷 玲菜 ミズタニ レナ

Research Projects

Research Products

Co-Researchers

非ドメイン型バイオポリマーによる熱ストレス応答機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

局所的なRNAの量的制御による熱応答性核内構造体の形成維持機構と生理的意義の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study of novel stress response mechanism in human cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of functional domain of MALAT1 lncRNA in heat shock responsePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of lncRNAs regulating immune response

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of heat-response gene regulation through norvel nuclear body by containing the noncoding RNAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of the components of heat-responsible novel nuclear body containing MALAT1, a long noncoding RNAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Techniques for Analyzing Genome-wide Expression of Non-coding RNA2023

Author(s)

Journal Title

Data Source

[Journal Article] Long noncoding RNA and phase separation in cellular stress response2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of heat-inducible long noncoding RNA MALAT1-containing novel nuclear (HiNoCo) body2021

Author(s)

Journal Title

Data Source

[Journal Article] Identification of heat-inducible long noncoding RNA MALAT1 -containing novel nuclear (HiNoCo) body2021

Author(s)

Journal Title

Data Source

[Journal Article] hnRNPH1-MTR4 complex-mediated regulation of <i>NEAT1v2</i> stability is critical for <i>IL8</i> expression2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cells2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of novel heat shock-induced long non-coding RNA in human cells2020

Author(s)

Journal Title

DOI

Data Source

Onoguchi Rena 小野口玲菜

水谷玲菜ミズタニレナ