KUSAKA SACHIE 日下祐江

… Alternative Names

KUSAKA Sachie 日下祐江

Less

Researcher Number	30781314
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院工学研究科, 技術専門職員
Affiliation (based on the past Project Information) *help	2024: 大阪大学, 大学院工学研究科, 技術専門職員 2021 – 2024: 大阪大学, 大学院工学研究科, 技術職員 2017 – 2021: 大阪大学, 工学研究科, 技術職員
Review Section/Research Field	Principal Investigator Basic Section 47060:Clinical pharmacy-related Except Principal Investigator Basic Section 31010:Nuclear engineering-related / Medium-sized Section 31:Nuclear engineering, earth resources engineering, energy engineering, and related fields / Nuclear engineering
Keywords	Principal Investigator Drug Delivery System / 脳脊髄液内投与 / 血液脳関門 / ホウ素中性子捕捉療法(BNCT) / 質量分析イメージング / 脳腫瘍 / ホウ素薬剤 / 脳脊髄液投与 / 小動物用MRI / MALDI-MSI … More / ドラッグデリバリーシステム / BNCT / Drug delivery system / 脳脊髄液 / ホウ素中性子捕捉(BNCT) … More Except Principal Investigator BNCT / 減速材フィルター / 中性子とγ線の混在場 / 遮へい材フィルター / 中性子ガンマ線混在場 / ガラス線量計 / 中性子線量計測 / 照射プロトコル / Current/Flux比 / 多門照射 / 深部照射 / γ線量 / 鉛フィルター / 中性子/γ線混在場 / 線量評価 / 線量変換係数 / 応答関数 / 混在場 / 線量計測 / ガンマ線量 / 線量 / フィルター / 中性子・ガンマ線混在場 / MCNP5 / CdTe / リアルタイム測定 / ホウ素 / ガンマ線 / リアルタイム計測 / 478keV / ホウ素濃度 / 治療効果 / リアルタイム / GAGG / SPECT / T/N比 Less

Neutron Dose Measurement in A Neutron/Gamma-ray Mixed Field for BNCT
- Principal Investigator
  
  村田勲
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 31010:Nuclear engineering-related
- Research Institution
  Osaka University
Neutron Irradiation Protocol for BNCT to Realize Deep-seated Cancer Treatment
- Principal Investigator
  
  村田勲
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 31:Nuclear engineering, earth resources engineering, energy engineering, and related fields
- Research Institution
  Osaka University
Boron delivery to brain tumor using cerebrospinal fluid circulation with ex-vivo microimaging of boron drugs for BNCTPrincipal Investigator
- Principal Investigator
  
  日下祐江
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Osaka University
Study on cerebrospinal fluid administration of boron agent for brain tumor for BNCTPrincipal Investigator
- Principal Investigator
  
  KUSAKA Sachie
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Osaka University
Development of gamma-ray dose measurement method in a neutron/gamma-ray mixed field for BNCT
- Principal Investigator
  
  Murata Isao
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 31010:Nuclear engineering-related
- Research Institution
  Osaka University
Development of real-time T/N ratio measuring technique for BNCT
- Principal Investigator
  
  Murata Isao
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nuclear engineering
- Research Institution
  Osaka University

All 2025 2024 2023 2022 2020 2019 2018

All Journal Article Presentation Patent

[Journal Article] Evaluation of the distribution of the boron neutron capture therapy drug 4-borono-L-phenylalanine (BPA) in a rat brain tumor model using liquid chromatography/tandem mass spectrometry (LC-MS/MS)2025
- Author(s)
  Kusaka Sachie、Miyake Yumi、Tokumaru Yugo、Voulgaris Nikolaos、Murata Isao
- Journal Title
  
  Applied Radiation and Isotopes
  
  Volume: - Pages: 111832-111832
- DOI
  10.1016/j.apradiso.2025.111832
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14383
[Journal Article] Accurate gamma-ray dose measurement up to 10 MeV by glass dosimeter with a sensitivity control filter for BNCT2024
- Author(s)
  F. Kamisaki, T. Inoue, K. Tomiyoshi, M. Matsuki, K. Aoki, S. Kusaka, S. Tamaki, F. Sato, I. Murata
- Journal Title
  
  Applied Radiation and Isotopes
  
  Volume: 209 Pages: 111299-111299
- DOI
  10.1016/j.apradiso.2024.111299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H02648, KAKENHI-PROJECT-23K26589
[Journal Article] Design of Moderator Assemblies for Fast, Epithermal, or Thermal Neutron Dominated n-γ Mixed Fields Using a D-D Neutron Source2024
- Author(s)
  Zixu Xu, Kazuma Aoki, Shingo Tamaki, Sachie Kusaka, Yuuki Chimura & Isao Murata
- Journal Title
  
  Nuclear Technology
  
  Volume: - Issue: 7 Pages: 1496-1508
- DOI
  10.1080/00295450.2024.2410642
- Data Source
  KAKENHI-PROJECT-23K26589
[Journal Article] Therapeutic Effect of Boron Neutron Capture Therapy on Boronophenylalanine Administration via Cerebrospinal Fluid Circulation in Glioma Rat Models2024
- Author(s)
  Sachie Kusaka; Nikolaos Voulgaris; Kazuki Onishi; Junpei Ueda; Shigeyoshi Saito; Shingo Tamaki; Isao Murata; Takushi Takata; Minoru Suzuki
- Journal Title
  
  Cells
  
  Volume: 13 Issue: 19 Pages: 1610-1610
- DOI
  10.3390/cells13191610
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07994, KAKENHI-PROJECT-23K14383
[Journal Article] Response control of RPLGD for gamma-ray dose measurement using lead filters for BNCT2023
- Author(s)
  K. Tochitani, K. Tomiyoshi, T. Inoue, F. Kamisaki, M. Matsuki, K. Hiramatsu, K. Aoki, S. Kusaka, S. Tamaki, F. Sato, I. Murata
- Journal Title
  
  Applied Radiation and Isotopes
  
  Volume: 199 Pages: 110897-110897
- DOI
  10.1016/j.apradiso.2023.110897
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H02648
[Journal Article] Boron Delivery to Brain Cells via Cerebrospinal Fluid (CSF) Circulation in BNCT of Brain-Tumor-Model Rats -Ex Vivo Imaging of BPA Using MALDI Mass Spectrometry Imaging-2022
- Author(s)
  Kusaka Sachie、Miyake Yumi、Tokumaru Yugo、Morizane Yuri、Tamaki Shingo、Akiyama Yoko、Sato Fuminobu、Murata Isao
- Journal Title
  
  Life
  
  Volume: 12 Issue: 11 Pages: 1786-1786
- DOI
  10.3390/life12111786
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16412
[Journal Article] BNCT用ホウ素薬剤のための脳脊髄液を介した脳細胞への新たなアプローチ2022
- Author(s)
  日下祐江、村田勲
- Journal Title
  
  Precision Medicine
  
  Volume: 5 Pages: 67-72
- Data Source
  KAKENHI-PROJECT-19K16412
[Journal Article] Boron Delivery to Brain Cells via Cerebrospinal Fluid (CSF) Circulation for BNCT in a Rat Melanoma Model2022
- Author(s)
  Kusaka Sachie、Morizane Yuri、Tokumaru Yugo、Tamaki Shingo、Maemunah Indah Rosidah、Akiyama Yoko、Sato Fuminobu、Murata Isao
- Journal Title
  
  Biology
  
  Volume: 11 Issue: 3 Pages: 397-397
- DOI
  10.3390/biology11030397
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16412
[Journal Article] Cerebrospinal fluid-based boron delivery system may help increase the uptake boron for boron neutron capture therapy in veterinary medicine: A preliminary study with normal rat brain cells2022
- Author(s)
  Kusaka Sachie、Morizane Yuri、Tokumaru Yugo、Tamaki Shingo、Maemunah Indah Rosidah、Akiyama Yoko、Sato Fuminobu、Murata Isao
- Journal Title
  
  Research in Veterinary Science
  
  Volume: 148 Pages: 1-6
- DOI
  10.1016/j.rvsc.2022.04.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16412
[Journal Article] Matrix-Assisted Laser Desorption/Ionization (MALDI) Mass Spectrometry Imaging of L-4-Phenylalanineboronic Acid (BPA) in a Brain Tumor Model Rat for Boron Neutron Capture Therapy (BNCT)2022
- Author(s)
  Miyake Yumi、Kusaka Sachie、Murata Isao、Toyoda Michisato
- Journal Title
  
  Mass Spectrometry
  
  Volume: 11 Issue: 1 Pages: A0105-A0105
- DOI
  10.5702/massspectrometry.A0105
- ISSN
  2186-5116, 2187-137X
- Year and Date
  2022-12-20
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16412
[Journal Article] 脳腫瘍に対するBNCT 用ホウ素薬剤の脳脊髄液内投与法2020
- Author(s)
  日下祐江・村田勲
- Journal Title
  
  Medical Science Digest
  
  Volume: 46(8) Pages: 62-64
- Data Source
  KAKENHI-PROJECT-19K16412
[Journal Article] ラットの脳室内灌流法によるBNCT用ホウ素薬剤の脳脊髄液中濃度変化2020
- Author(s)
  日下祐江・村田勲
- Journal Title
  
  Precision Medicine
  
  Volume: 3(13) Pages: 79-83
- Data Source
  KAKENHI-PROJECT-19K16412
[Patent] 質量分析イメージング法2022
- Inventor(s)
  三宅ゆみ、豊田岐聡、日下祐江、村田勲
- Industrial Property Rights Holder
  三宅ゆみ、豊田岐聡、日下祐江、村田勲
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-19K16412
[Presentation] ホウ素中性子捕捉療法における深部がん治療のための中性子ビーム特性の検討2024
- Author(s)
  守實友梨、日下祐江、玉置真悟、村田勲
- Organizer
  第20回日本中性子捕捉療法学会学術大会
- Data Source
  KAKENHI-PROJECT-23K17895
[Presentation] Examination of neutron beam properties to reach deep-seated cancer on BNCT2024
- Author(s)
  Yuri Morizane, Sachie Kusaka, Shingo Tamaki, Isao Murata
- Organizer
  20th Inernational Congress on Neutron Capture Therapy (ICNCT20)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K17895
[Presentation] Evaluation of the distribution of BPA in a rat brain tumor model using MALDI-MSI in comparison with LC/MS/MS2024
- Author(s)
  Sachie Kusaka, Yumi Miyake, Yugo Tokumaru, Nikolaos Voulgaris, Shingo Tamaki, Isao Murata
- Organizer
  The 20th International Congress on Neutron Capture Therapy (ICNCT)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14383
[Presentation] グリオーマモデルラットの脳脊髄液循環を介したBPA投与におけるBNCTの効果2024
- Author(s)
  日下祐江、ブルガリスニコラオス、大西一輝、上田淳平, 齋藤茂芳, 玉置真悟, 村田勲, 高田卓志, 鈴木実
- Organizer
  第20回日本中性子捕捉療法学会学術大会
- Data Source
  KAKENHI-PROJECT-23K14383
[Presentation] 中性子・ガンマ線混在場における混合材料フィルターを用いたガラス線量計によるガンマ線量測定手法の開発2024
- Author(s)
  Kazuma Aoki, Xu Zixu, Masaya Matsuki, Sachie Kusaka, Shingo Tamaki, Isao Murata
- Organizer
  第20回日本中性子捕捉療法学会学術大会
- Data Source
  KAKENHI-PROJECT-23K26589
[Presentation] Development of n-γ mixed fields based on a D-D neutron source for validation of material-filtered RPLGD for BNCT2023
- Author(s)
  Zixu Xu*, Kazuma Aoki, Shingo Tamaki, Sachie Kusaka, and Isao Murata Graduate School of Engineering, Osaka University, Osaka, Japan
- Organizer
  THE 11TH INTERNATIONAL SYMPOSIUM ON RADIATION SAFETY AND DETECTION TECHNOLOGY
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02648
[Presentation] 脳腫瘍モデルラットにおけるホウ素中性子捕捉治療用薬剤ホウ素化フェニルアラニン（BPA）のMALDI質量分析イメージングに関する検討2023
- Author(s)
  三宅ゆみ、日下祐江、得丸裕伍、村田勲、豊田岐聡
- Organizer
  第71回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-23K14383
[Presentation] グリオーマモデルラットに対するBPAの脳脊髄液内投与による脳内動態イメージング2023
- Author(s)
  日下祐江、三宅ゆみ、得丸裕伍、Nikolaos Voulgaris、玉置真悟、秋山庸子、佐藤文信、村田勲
- Organizer
  第19回日本中性子捕捉療法学会
- Data Source
  KAKENHI-PROJECT-23K14383
[Presentation] Boron delivery using cerebrospinal fluid (CSF) circulation to brain cells in brain tumor model rats for BNCT －Ex vivo imaging of BPA using MALDI mass spectrometry imaging-2022
- Author(s)
  Sachie Kusaka, Yumi Miyake, Yugo Tokumaru, Yuri Morizane, Shingo Tamaki, Yoko Akiyama, Fuminobu Sato, Isao Murata
- Organizer
  Young Researchers BNCT meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16412
[Presentation] Characterization of various types of n-γ mixed fields based on a D-D neutron source2022
- Author(s)
  Zixu Xu, Masaya Matsuki, Kazuma Aoki, Shingo Tamaki, Sachie Kusaka, and Isao Murata
- Organizer
  2022 Symposium on Nucl. Data
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02648
[Presentation] Fundamental Study on T/N Ratio Determination by Ex-vivo Micro-imaging of BPA with a Brain Tumor Model Rat for BNCT-Differences in ionization efficiency between tumor and normal tissues with MALDI-MSI-2022
- Author(s)
  Yugo Tokumaru, Sachie Kusaka, Yumi Miyake, Yoko Akiyama, Fuminobu Sato, Isao Murata
- Organizer
  Young Researchers BNCT meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16412
[Presentation] Pharmacological investigation based on ex vivo imaging of the boron-uptake in rat brain tumor model for boron neutron capture therapy2022
- Author(s)
  Sachie Kusaka, Yumi Miyake, Yugo Tokumaru, Yuri Morizane, Shingo Tamaki, Yoko Akiyama, Fuminobu Sato, Isao Murata
- Organizer
  Veterinary Cancer Society annual conference 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16412
[Presentation] Gamma-Ray Dosimeter Development Using Radio-Photoluminescence Glass Dosimeter (RPLGD) in Neutron/Gamma-Ray Mixed Field for BNCT -Control of the response of RPLGD with a shielding filter-2022
- Author(s)
  Masaya Matsuki, Fumiaki Kamisaki, Zixu Xu, Shingo Tamaki, Sachie Kusaka, Fuminobu Sato, Isao Murata
- Organizer
  Young Researchers’ BNCT Meeting 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02648
[Presentation] Development of n-γ mixed fields based on a D-D neutron source for validation of material-filtered RPLGD for BNCT2022
- Author(s)
  Zixu Xua, Masaya Matsukia, Kazuma Aokib, Shingo Tamakia, Sachie Kusakaa, Isao Murata
- Organizer
  37th Radiation Detector and Its Use
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02648
[Presentation] BNCTにおけるラットの脳腫瘍に対するホウ素脳脊髄液内投与法の検討2020
- Author(s)
  日下　祐江
- Organizer
  獣医学BNCTシンポジウム
- Data Source
  KAKENHI-PROJECT-19K16412
[Presentation] BNCTのためのT/N-SPECTのコリメータ設計2019
- Author(s)
  柴田　紗希、守實　友梨、玉置　真悟、日下　祐江、村田　勲
- Organizer
  第16回日本中性子捕捉療法学会学術大会、9月7日～8日、京都大学宇治キャンパス宇治おうばくプラザ、P1-07 (2019).
- Data Source
  KAKENHI-PROJECT-15H04242
[Presentation] Development of Gamma-ray Dosimeter Using Radio-Photoluminescence Glass Dosimeter and Gamma-ray Filter in A Neutron/Gamma-ray Mixed Field for BNCT2019
- Author(s)
  Tokiya Inoue, Koki Tochitani, Shingo Tamaki, Sachie Kusaka, Fuminobu Sato, Isao Murata
- Organizer
  10th Young Researchers BNCT Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02648
[Presentation] Design of collimator for T/N-SPECT for BNCT2018
- Author(s)
  Saki Shibata, Kentaro Minami, Ryosuke Ohya, Yuri Morizane, Shingo Tamaki, Sachie Kusaka, Fuminobu Sato, Isao Murata
- Organizer
  18th International Congress on Neutron Capture Therapy, Oct. 28-Nov. 2, 2018, Taipei, Taiwan
- Data Source
  KAKENHI-PROJECT-15H04242
[Presentation] Design of collimator for T/N-SPECT for BNCT2018
- Author(s)
  Saki Shibata, Ryosuke Ohya, Kentaro Minami, Shingo Tamaki, Sachie Kusaka, Fuminobu Sato, Isao Murata
- Organizer
  18th International Congress on Neutron Capture Therapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04242

1. Murata Isao (30273600)

# of Collaborated Projects: 4 results

# of Collaborated Products: 14 results
2. 佐藤文信 (40332746)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
3. 加藤逸郎 (60314390)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. 宮丸広幸 (80243187)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. 玉置真悟 (10823396)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
6. 杉本久司 (40379144)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 伊達道淳 (50379145)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 吉田茂生 (70174927)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 吉橋幸子 (20403157)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 鈴木実

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KUSAKA SACHIE 日下 祐江

KUSAKA Sachie 日下 祐江

Research Projects

Research Products

Co-Researchers

Neutron Dose Measurement in A Neutron/Gamma-ray Mixed Field for BNCT

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Neutron Irradiation Protocol for BNCT to Realize Deep-seated Cancer Treatment

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Boron delivery to brain tumor using cerebrospinal fluid circulation with ex-vivo microimaging of boron drugs for BNCTPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study on cerebrospinal fluid administration of boron agent for brain tumor for BNCTPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of gamma-ray dose measurement method in a neutron/gamma-ray mixed field for BNCT

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of real-time T/N ratio measuring technique for BNCT

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Evaluation of the distribution of the boron neutron capture therapy drug 4-borono-L-phenylalanine (BPA) in a rat brain tumor model using liquid chromatography/tandem mass spectrometry (LC-MS/MS)2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Accurate gamma-ray dose measurement up to 10 MeV by glass dosimeter with a sensitivity control filter for BNCT2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Design of Moderator Assemblies for Fast, Epithermal, or Thermal Neutron Dominated n-γ Mixed Fields Using a D-D Neutron Source2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Therapeutic Effect of Boron Neutron Capture Therapy on Boronophenylalanine Administration via Cerebrospinal Fluid Circulation in Glioma Rat Models2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Response control of RPLGD for gamma-ray dose measurement using lead filters for BNCT2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Boron Delivery to Brain Cells via Cerebrospinal Fluid (CSF) Circulation in BNCT of Brain-Tumor-Model Rats -Ex Vivo Imaging of BPA Using MALDI Mass Spectrometry Imaging-2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] BNCT用ホウ素薬剤のための脳脊髄液を介した 脳細胞への新たなアプローチ2022

Author(s)

Journal Title

Data Source

[Journal Article] Boron Delivery to Brain Cells via Cerebrospinal Fluid (CSF) Circulation for BNCT in a Rat Melanoma Model2022

Author(s)

Journal Title

DOI

Data Source

KUSAKA SACHIE 日下祐江

KUSAKA Sachie 日下祐江

[Journal Article] BNCT用ホウ素薬剤のための脳脊髄液を介した脳細胞への新たなアプローチ2022

[Journal Article] 脳腫瘍に対するBNCT 用ホウ素薬剤の脳脊髄液内投与法2020

[Journal Article] ラットの脳室内灌流法によるBNCT用ホウ素薬剤の脳脊髄液中濃度変化2020

[Presentation] 中性子・ガンマ線混在場における混合材料フィルターを用いたガラス線量計によるガンマ線量測定手法の開発2024