Sugimoto Kazutaka 杉本至健

Researcher Number	30786075
Other IDs
Affiliation (Current)	2025: 山口大学, 医学部附属病院, 助教
Affiliation (based on the past Project Information) *help	2020 – 2024: 山口大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related
Keywords	Principal Investigator Spreading depolarization / CSD / Spreading depression / Autoregulation / 皮質拡延性抑制 / 脳虚血 / 拡延性抑制 / PID / 広汎性脱分極 / optogenetics / MCAO

皮質拡延性脱分極 (拡延性抑制)と脳血管自動調節能の関係性についての研究Principal Investigator
- Principal Investigator
  
  杉本至健
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Yamaguchi University
広汎性脱分極 (皮質拡延性抑制)と脳血管自動調節能の関係性についての研究Principal Investigator
- Principal Investigator
  
  杉本至健
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Yamaguchi University
広汎性脱分極 (皮質拡延性抑制)が脳虚血に及ぼす影響についての研究Principal Investigator
- Principal Investigator
  
  杉本至健
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Yamaguchi University

All 2023 2022 2021 2020

All Journal Article Presentation Book

[Book] エビデンスとガイドラインに基づく脳動脈瘤とくも膜下出血2023
- Author(s)
  杉本至健
- Total Pages
  256
- Publisher
  医学書院
- ISBN
  4260050982
- Data Source
  KAKENHI-PROJECT-22K16661
[Book] エビデンスとガイドラインに基づく脳動脈瘤とくも膜下出血2023
- Author(s)
  杉本至健
- Total Pages
  256
- Publisher
  医学書院
- ISBN
  4260050982
- Data Source
  KAKENHI-PROJECT-20K17970
[Journal Article] Optogenetic Spreading Depolarizations Do Not Worsen Acute Ischemic Stroke Outcome2023
- Author(s)
  Sugimoto Kazutaka、Yang Joanna、Fischer Paul、Takizawa Tsubasa、Mulder Inge A.、Qin Tao、Erdogan Taylan D.、Yaseen Mohammad A.、Sakadzic Sava、Chung David Y.、Ayata Cenk
- Journal Title
  
  Stroke
  
  Volume: 54 Issue: 4 Pages: 1110-1119
- DOI
  10.1161/strokeaha.122.041351
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16661, KAKENHI-PROJECT-20K17970
[Journal Article] Spreading Depolarizations Suppress Hematoma Growth in Hyperacute Intracerebral Hemorrhage in Mice2023
- Author(s)
  Fischer Paul、Tamim Isra、Sugimoto Kazutaka、Morais Andreia、Imai Takahiko、Takizawa Tsubasa、Qin Tao、Schlunk Frieder、Endres Matthias、Yaseen Mohammad A.、Chung David Y.、Sakadzic Sava、Ayata Cenk
- Journal Title
  
  Stroke
  
  Volume: 54 Issue: 10 Pages: 2640-2651
- DOI
  10.1161/strokeaha.123.042632
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17970
[Journal Article] Focal Subcortical White Matter Lesions Disrupt Resting State Cortical Interhemispheric Functional Connectivity in Mice2021
- Author(s)
  Aykan Sanem A、Xie Hongyu、Lai James Han、Zheng Yi、Chung David Y、Kura Sreekanth、Anzabi Maryam、Sugimoto Kazutaka、McAllister Lauren M、Yaseen M Abbas、Boas David A、Whalen Michael J、Sakadzic Sava、Ayata Cenk
- Journal Title
  
  Cerebral Cortex
  
  Volume: 31 Issue: 11 Pages: 4958-4969
- DOI
  10.1093/cercor/bhab134
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17970
[Journal Article] Rapid hematoma growth triggers spreading depolarizations in experimental intracortical hemorrhage2021
- Author(s)
  Fischer Paul、Sugimoto Kazutaka、Chung David Y、Tamim Isra、Morais Andreia、Takizawa Tsubasa、Qin Tao、Gomez Carlos A、Schlunk Frieder、Endres Matthias、Yaseen Mohammad A、Sakadzic Sava、Ayata Cenk
- Journal Title
  
  Journal of Cerebral Blood Flow & Metabolism
  
  Volume: 41 Issue: 6 Pages: 1264-1276
- DOI
  10.1177/0271678x20951993
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17970
[Journal Article] Intracranial pressure spikes trigger spreading depolarizations2021
- Author(s)
  Oka Fumiaki、Sadeghian Homa、Yaseen Mohammad A、Fu Buyin、Kura Sreekanth、Qin Tao、Sakadadzic Sava、Sugimoto Kazutaka、Inoue Takao、Ishihara Hideyuki、Nomura Sadahiro、Suzuki Michiyasu、Ayata Cenk
- Journal Title
  
  Brain
  
  Volume: 145 Issue: 1 Pages: 194-207
- DOI
  10.1093/brain/awab256
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09458, KAKENHI-PROJECT-20K17970
[Journal Article] Association Between Spreading Depolarization and Delayed Cerebral Ischemia After Subarachnoid Hemorrhage: Post Hoc Analysis of a Randomized Trial of the Effect of Cilostazol on Delayed Cerebral Ischemia2021
- Author(s)
  Kawano Akiko、Sugimoto Kazutaka、Nomura Sadahiro、Inoue Takao、Kawano Reo、Oka Fumiaki、Sadahiro Hirokazu、Ishihara Hideyuki、Suzuki Michiyasu
- Journal Title
  
  Neurocritical Care
  
  Volume: 35 Issue: S2 Pages: 91-99
- DOI
  10.1007/s12028-021-01330-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09529, KAKENHI-PROJECT-20K17970
[Journal Article] Intravenous Endothelin‐1 Infusion Does Not Induce Aura or Headache in Migraine Patients With Aura2020
- Author(s)
  Hougaard Anders、Younis Samaira、Iljazi Afrim、Sugimoto Kazutaka、Ayata Cenk、Ashina Messoud
- Journal Title
  
  Headache: The Journal of Head and Face Pain
  
  Volume: 60 Issue: 4 Pages: 724-734
- DOI
  10.1111/head.13753
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17970
[Journal Article] Cerebrovascular effects of endothelin-1 investigated using high-resolution magnetic resonance imaging in healthy volunteers2020
- Author(s)
  Hougaard Anders、Younis Samaira、Iljazi Afrim、Haanes Kristian A、Lindberg Ulrich、Vestergaard Mark B、Amin Faisal M、Sugimoto Kazutaka、Kruse Lars S、Ayata Cenk、Ashina Messoud
- Journal Title
  
  Journal of Cerebral Blood Flow & Metabolism
  
  Volume: 40 Issue: 8 Pages: 1685-1694
- DOI
  10.1177/0271678x19874295
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17970
[Journal Article] Anti‐migraine Calcitonin Gene?Related Peptide Receptor Antagonists Worsen Cerebral Ischemic Outcome in Mice2020
- Author(s)
  Mulder Inge A.、Li Mei、Vries Tessa、Qin Tao、Yanagisawa Takeshi、Sugimoto Kazutaka、Bogaerdt Antoon、Danser A. H. Jan、Wermer Marieke J. H.、Maagdenberg Arn M. J. M.、MaassenVanDenBrink Antoinette、Ferrari Michel D.、Ayata Cenk
- Journal Title
  
  Annals of Neurology
  
  Volume: 88 Issue: 4 Pages: 771-784
- DOI
  10.1002/ana.25831
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17970
[Journal Article] Non-invasively triggered spreading depolarizations induce a rapid pro-inflammatory response in cerebral cortex2020
- Author(s)
  Takizawa Tsubasa、Qin Tao、Lopes de Morais Andreia、Sugimoto Kazutaka、Chung Joon Yong、Morsett Liza、Mulder Inge、Fischer Paul、Suzuki Tomoaki、Anzabi Maryam、Bohm Maximilian、Qu Wen-sheng、Yanagisawa Takeshi、Hickman Suzanne、Khoury Joseph El、Whalen Michael J、Harriott Andrea M、Chung David Y、Ayata Cenk
- Journal Title
  
  Journal of Cerebral Blood Flow & Metabolism
  
  Volume: 40 Issue: 5 Pages: 1117-1131
- DOI
  10.1177/0271678x19859381
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17970
[Journal Article] Peri-Infarct Hot-Zones Have Higher Susceptibility to Optogenetic Functional Activation-Induced Spreading Depolarizations2020
- Author(s)
  Sugimoto Kazutaka、Chung David Y.、Bohm Maximilian、Fischer Paul、Takizawa Tsubasa、Aslihan Aykan Sanem、Qin Tao、Yanagisawa Takeshi、Harriott Andrea、Oka Fumiaki、Yaseen Mohammad A.、Sakadzic Sava、Ayata Cenk
- Journal Title
  
  Stroke
  
  Volume: 51 Issue: 8 Pages: 2526-2535
- DOI
  10.1161/strokeaha.120.029618
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17970
[Journal Article] Differential effects of anesthetics on resting state functional connectivity in the mouse2020
- Author(s)
  Xie Hongyu、Chung David Y、Kura Sreekanth、Sugimoto Kazutaka、Aykan Sanem A、Wu Yi、Sakadzic Sava、Yaseen Mohammad A、Boas David A、Ayata Cenk
- Journal Title
  
  Journal of Cerebral Blood Flow & Metabolism
  
  Volume: 40 Issue: 4 Pages: 875-884
- DOI
  10.1177/0271678x19847123
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17970
[Journal Article] Intravascular Endothelin-1 does not trigger or increase susceptibility to Spreading Depolarizations2020
- Author(s)
  Sugimoto Kazutaka、Morais Andreia、Sadeghian Homa、Qin Tao、Chung David Y.、Ashina Messoud、Hougaard Anders、Ayata Cenk
- Journal Title
  
  The Journal of Headache and Pain
  
  Volume: 21 Issue: 1 Pages: 127-127
- DOI
  10.1186/s10194-020-01194-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17970
[Journal Article] Neurovascular coupling during optogenetic functional activation: Local and remote stimulus-response characteristics, and uncoupling by spreading depression2020
- Author(s)
  Bohm Maximilian、Chung David Y、Gomez Carlos A、Qin Tao、Takizawa Tsubasa、Sadeghian Homa、Sugimoto Kazutaka、Sakadzic Sava、Yaseen Mohammad A、Ayata Cenk
- Journal Title
  
  Journal of Cerebral Blood Flow & Metabolism
  
  Volume: 40 Issue: 4 Pages: 808-822
- DOI
  10.1177/0271678x19845934
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17970
[Journal Article] Spreading Depolarizations and Subarachnoid Hemorrhage2020
- Author(s)
  Sugimoto Kazutaka、Chung David Y.
- Journal Title
  
  Neurotherapeutics
  
  Volume: 17 Issue: 2 Pages: 497-510
- DOI
  10.1007/s13311-020-00850-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17970
[Presentation] 頭部外傷への基本的対応と新しい病態への対応：Spreading depolarizationとは2023
- Author(s)
  杉本至健
- Organizer
  第46回日本脳神経外傷学会
- Data Source
  KAKENHI-PROJECT-20K17970
[Presentation] 頭部外傷への基本的対応と新しい病態への対応：Spreading depolarizationとは2023
- Author(s)
  杉本至健
- Organizer
  第46回日本脳神経外傷学会
- Invited
- Data Source
  KAKENHI-PROJECT-22K16661
[Presentation] Optogenetic spreading depolarizationは脳虚血を増悪させない2022
- Author(s)
  杉本至健
- Organizer
  第47回日本脳神経外科学会学術総会
- Data Source
  KAKENHI-PROJECT-20K17970
[Presentation] 虚血巣周囲のfunctional activationはPeri-infarct spreading depolarizationを誘発する2021
- Author(s)
  杉本至健
- Organizer
  第49回日本頭痛学会総会
- Data Source
  KAKENHI-PROJECT-20K17970
[Presentation] Optogenetic spreading depolarizationは脳虚血を増悪させない2021
- Author(s)
  杉本至健
- Organizer
  第80回日本脳神経外科学会学術総会
- Data Source
  KAKENHI-PROJECT-20K17970

1. 岡史朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 貞廣浩和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sugimoto Kazutaka 杉本 至健

Research Projects

Research Products

Co-Researchers

皮質拡延性脱分極 (拡延性抑制)と脳血管自動調節能の関係性についての研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

広汎性脱分極 (皮質拡延性抑制)と脳血管自動調節能の関係性についての研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

広汎性脱分極 (皮質拡延性抑制)が脳虚血に及ぼす影響についての研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] エビデンスとガイドラインに基づく脳動脈瘤とくも膜下出血2023

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] エビデンスとガイドラインに基づく脳動脈瘤とくも膜下出血2023

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Optogenetic Spreading Depolarizations Do Not Worsen Acute Ischemic Stroke Outcome2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Spreading Depolarizations Suppress Hematoma Growth in Hyperacute Intracerebral Hemorrhage in Mice2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Focal Subcortical White Matter Lesions Disrupt Resting State Cortical Interhemispheric Functional Connectivity in Mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Rapid hematoma growth triggers spreading depolarizations in experimental intracortical hemorrhage2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Intracranial pressure spikes trigger spreading depolarizations2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Association Between Spreading Depolarization and Delayed Cerebral Ischemia After Subarachnoid Hemorrhage: Post Hoc Analysis of a Randomized Trial of the Effect of Cilostazol on Delayed Cerebral Ischemia2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Intravenous Endothelin‐1 Infusion Does Not Induce Aura or Headache in Migraine Patients With Aura2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cerebrovascular effects of endothelin-1 investigated using high-resolution magnetic resonance imaging in healthy volunteers2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Anti‐migraine Calcitonin Gene?Related Peptide Receptor Antagonists Worsen Cerebral Ischemic Outcome in Mice2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Non-invasively triggered spreading depolarizations induce a rapid pro-inflammatory response in cerebral cortex2020

Sugimoto Kazutaka 杉本至健