Barker Nicholas NICHOLAS BARKER

Researcher Number	30787651
Affiliation (based on the past Project Information) *help	2017 – 2019: 金沢大学, その他部局等, リサーチ・プロフェッサー
Review Section/Research Field	Principal Investigator Tumor biology
Keywords	Principal Investigator 再生医学 / 遺伝子 / 発現制御 / 細胞・組織 / 再生医療 / 癌 / organoid / inflammation / mouse model / gastric cancer … More / Organoid / Lgr5 / Inflammation / Mouse model / Gastric cancer Less

Developing mouse models of inflammation-driven invasive gastric cancer to reveal novel therapeutic targetsPrincipal Investigator
- Principal Investigator
  
  Barker Nicholas
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Tumor biology
- Research Institution
  Kanazawa University

All 2020 2019 2018 2017

All Journal Article

[Journal Article] AQP5 enriches for stem cells and cancer origins in the distal stomach2020
- Author(s)
  Tan Si Hui、Barker Nick et al.
- Journal Title
  
  Nature
  
  Volume: 578 Issue: 7795 Pages: 437-443
- DOI
  10.1038/s41586-020-1973-x
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01399, KAKENHI-PROJECT-17K07161
[Journal Article] Distinct Localization of Mature HGF from its Precursor Form in Developing and Repairing the Stomach.2019
- Author(s)
  Jangphattananont N, Sato H, Imamura R, Sakai K, Terakado Y, Murakami K, Barker N, Oshima H, Oshima M, Takagi J, Kato Y, Yano S, Matsumoto K
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 12 Issue: 12 Pages: 2955-2955
- DOI
  10.3390/ijms20122955
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15306, KAKENHI-PROJECT-17H01399, KAKENHI-PROJECT-17H01420, KAKENHI-PROJECT-19H03498, KAKENHI-PROJECT-19H03499, KAKENHI-PROJECT-17K07161, KAKENHI-PROJECT-18K19298
[Journal Article] A contemporary snapshot of intestinal stem cells and their regulation2019
- Author(s)
  Seishima Ryo、Barker Nick
- Journal Title
  
  Differentiation
  
  Volume: 108 Pages: 3-7
- DOI
  10.1016/j.diff.2019.01.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H01399
[Journal Article] The Function of Lgr5+ Cells in the Gastric Antrum Does Not Require Fzd7 or Myc In Vivo2019
- Author(s)
  Flanagan Dustin、Barker Nick、Ernst Matthias、Vincan Elizabeth、Phesse Toby
- Journal Title
  
  Biomedicines
  
  Volume: 7 Issue: 3 Pages: 50-50
- DOI
  10.3390/biomedicines7030050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H01399
[Journal Article] Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development2019
- Author(s)
  Seishima Ryo、Leung Carly、Yada Swathi、Murad Katzrin Bte Ahmed、Tan Liang Thing、Hajamohideen Amin、Tan Si Hui、Itoh Hideki、Murakami Kazuhiro、Ishida Yoshihiro、Nakamizo Satoshi、Yoshikawa Yusuke、Wong Esther、Barker Nick
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 1-17
- DOI
  10.1038/s41467-019-13363-3
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01399, KAKENHI-PROJECT-17K07161
[Journal Article] Bortezomib Stabilizes and Activates p53 in Proliferative Compartments of Both Normal and Tumor Tissues In Vivo2019
- Author(s)
  Xue Yuezhen、Barker Nick、Hoon Shawn、He Pingping、Thakur Teena、Abdeen Shifana Raja、Maruthappan Priadarsini、Ghadessy Farid J.、Lane David P.
- Journal Title
  
  Cancer Research
  
  Volume: 79 Issue: 14 Pages: 3595-3607
- DOI
  10.1158/0008-5472.can-18-3744
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H01399
[Journal Article] Frizzled-7 Is Required for Wnt Signaling in Gastric Tumors with and Without Apc Mutations2019
- Author(s)
  Flanagan Dustin J.、Barker Nick、Costanzo Natasha S. Di、Mason Elizabeth A.、Gurney Austin、Meniel Valerie S.、Koushyar Sarah、Austin Chloe R.、Ernst Matthias、Pearson Helen B.、Boussioutas Alex、Clevers Hans、Phesse Toby J.、Vincan Elizabeth
- Journal Title
  
  Cancer Research
  
  Volume: 79 Issue: 5 Pages: 970-981
- DOI
  10.1158/0008-5472.can-18-2095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H01399
[Journal Article] Stem cells in 2017: Digesting recent stem cell advances in the gut2018
- Author(s)
  Barker Nick
- Journal Title
  
  Nature Reviews Gastroenterology & Hepatology
  
  Volume: 15 Issue: 2 Pages: 78-80
- DOI
  10.1038/nrgastro.2017.176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H01399
[Journal Article] Recent Advances in Lgr5 + Stem Cell Research2018
- Author(s)
  Leung Carly、Tan Si Hui、Barker Nick
- Journal Title
  
  Trends in Cell Biology
  
  Volume: 28 Issue: 5 Pages: 380-391
- DOI
  10.1016/j.tcb.2018.01.010
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01399
[Journal Article] Lgr5-Expressing Chief Cells Drive Epithelial Regeneration and Cancer in the Oxyntic Stomach.2017
- Author(s)
  Leushacke M, Tan SH, Wong A, Yada S, Hajamohideen A, Tan LT, Goh J, Wong E, Denil SL, Murakami K & Barker N
- Journal Title
  
  Nature Cell Biology
  
  Volume: 7 Issue: 7 Pages: 774-786
- DOI
  10.1038/ncb3541
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01399

1. 佐藤拓輝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Barker Nicholas NICHOLAS BARKER

Research Projects

Research Products

Co-Researchers

Developing mouse models of inflammation-driven invasive gastric cancer to reveal novel therapeutic targetsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] AQP5 enriches for stem cells and cancer origins in the distal stomach2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Distinct Localization of Mature HGF from its Precursor Form in Developing and Repairing the Stomach.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A contemporary snapshot of intestinal stem cells and their regulation2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Function of Lgr5+ Cells in the Gastric Antrum Does Not Require Fzd7 or Myc In Vivo2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Bortezomib Stabilizes and Activates p53 in Proliferative Compartments of Both Normal and Tumor Tissues In Vivo2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Frizzled-7 Is Required for Wnt Signaling in Gastric Tumors with and Without Apc Mutations2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Stem cells in 2017: Digesting recent stem cell advances in the gut2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Recent Advances in Lgr5 + Stem Cell Research2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lgr5-Expressing Chief Cells Drive Epithelial Regeneration and Cancer in the Oxyntic Stomach.2017

Author(s)

Journal Title

DOI

Data Source