HANAKI Takehiko 花木武彦

Researcher Number	30788592
Other IDs
Affiliation (Current)	2025: 鳥取大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2021 – 2023: 鳥取大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related Except Principal Investigator Basic Section 53010:Gastroenterology-related / Basic Section 55020:Digestive surgery-related
Keywords	Principal Investigator 膵癌 / Tyro3 / EMT / EndMT / Exosome / YAP/TAZ経路 / 上皮間葉転換 / TAZ / YAP / YAP/TAZ … More / TAP/TAZ経路 / 細胞極性 / aPKC / 糖尿病 / 高血糖 … More Except Principal Investigator 長鎖非コードRNA / 腫瘍免疫 / CD24 / 腫瘍内マクロファージ / 肝細胞癌 / lncRNA / NEAT1 / 創傷被覆剤 / 胆汁瘻 / キチンナノファイバー / TGF-β/Smad経路 / 星細胞 / 胆汁漏 / 肝切除 / キチン / TGF-β/Smad pathway / Hepatic stellate cell / Bile leakage / Hepatectomy / Chitin Less

膵癌Exosomal Tyro3を介した内皮間葉転換と膵癌進展機構の解明Principal Investigator
- Principal Investigator
  
  花木武彦
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Tottori University
肝細胞がんにおける新たな免疫回避メカニズムの解明
- Principal Investigator
  
  土谷博之
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tottori University
キチンナノファイバーのTGF-β/Smad経路を介した肝切後胆汁漏予防効果の検討
- Principal Investigator
  
  徳安成郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Tottori University
Disruption of cell polarity signaling promotes pancreatic cancer progression via activation of the YAP/TAZ pathwayPrincipal Investigator
- Principal Investigator
  
  HANAKI Takehiko
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Tottori University

All 2023 2022 2021

All Journal Article Presentation

[Journal Article] Right thoracoscopic resection in the supine position for recurrent pretracheal lymph nodes after esophagectomy2023
- Author(s)
  Kono Y, Murakami Y, Hanaki T, Kihara K, Yamamoto M, Tokuyasu N, Takano S, Sakamoto T, Saito H, Hasegawa T, Fujiwara Y.
- Journal Title
  
  Asian Journal of Endoscopic Surgery
  
  Volume: 16 Issue: 3 Pages: 571-574
- DOI
  10.1111/ases.13186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K15521
[Journal Article] Preoperative Osteopenia as Risk Factor for Death from Other Diseases After Gastrectomy in Elderly Patients2023
- Author(s)
  Shimizu S, Matsunaga T, Sakano YU, Makinoya M, Shishido Y, Miyatani K, Kono Y, Murakami Y, Hanaki T, Kihara K, Yamamoto M, Tokuyasu N, Takano S, Sakamoto T, Hasegawa T, Fujiwara Y.
- Journal Title
  
  In vivo
  
  Volume: 37 Issue: 6 Pages: 2662-2668
- DOI
  10.21873/invivo.13375
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15521
[Journal Article] Current Value of Perioperative Therapies for Resectable or Borderline Resectable Pancreatic Cancer2023
- Author(s)
  Murakami Y, Sakamoto T, Hanaki T, Tokuyasu N, Fujiwara Y
- Journal Title
  
  Yonago Acta Medica
  
  Volume: 66 Issue: 2 Pages: 202-207
- DOI
  10.33160/yam.2023.05.014
- ISSN
  0513-5710, 1346-8049
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15521
[Journal Article] Evaluation of perioperative D-dimer concentration for predicting postoperative deep vein thrombosis following hepatobiliary-pancreatic surgery2023
- Author(s)
  Sakamoto T, Murakami Y, Hanaki T, Kihara K, Matsunaga T, Yamamoto M, Takano S, Tokuyasu N, Hasegawa T, Fujiwara Y.
- Journal Title
  
  Surgery Today
  
  Volume: 53 Issue: 7 Pages: 773-781
- DOI
  10.1007/s00595-023-02645-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K15521
[Journal Article] Surgical Outcomes of Robotic Distal Pancreatectomy Versus Laparoscopic Distal Pancreatectomy at a Hospital in a Sparsely Populated Area2023
- Author(s)
  Sakamoto T, Kishino M, Murakami Y, Miyatani K, Shishido Y, Hanaki T, Matsunaga T, Yamamoto M, Tokuyasu N, Fujiwara Y.
- Journal Title
  
  Yonago Acta Medica
  
  Volume: 66 Issue: 3 Pages: 375-379
- DOI
  10.33160/yam.2023.08.010
- ISSN
  0513-5710, 1346-8049
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15521
[Journal Article] Impact of Robot-Assisted Minimally Invasive Esophagectomy for Esophageal Cancer: A Propensity Score-Matched Short-Term Analysis2023
- Author(s)
  Matsunaga T, Shishido Y, Saito H, Sakano Y, Makinoya M, Miyauchi W, Shimizu S, Miyatani K, Kono Y, Murakami Y, Hanaki T, Kihara K, Yamamoto M, Tokuyasu N, Takano S, Sakamoto T, Hasegawa T, Fujiwara Y.
- Journal Title
  
  Yonago Acta Medica
  
  Volume: 66 Issue: 2 Pages: 239-245
- DOI
  10.33160/yam.2023.05.012
- ISSN
  0513-5710, 1346-8049
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15521
[Journal Article] Prognostic significance of the cachexia index in patients with unresectable advanced gastric cancer receiving palliative chemotherapy: a retrospective single-center study2023
- Author(s)
  Matsunaga T, Satio H, Sakano Y, Makinoya M, Shimizu S, Shishido Y, Miyatani K, Hanaki T, Kihara K, Yamamoto M, Tokuyasu N, Takano S, Sakamoto T, Hasegawa T, Fujiwara Y.
- Journal Title
  
  Surgery Today
  
  Volume: 54 Issue: 3 Pages: 231-239
- DOI
  10.1007/s00595-023-02721-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K15521
[Journal Article] Efficacy of indocyanine green systemic administration for bile leak detection after hepatectomy: a protocol for a prospective single-arm clinical trial with a historical control group2023
- Author(s)
  Takehiko Hanaki, Keisuke Goto, Naruo Tokuyasu, et al.
- Journal Title
  
  BMJ open
  
  Volume: 13(3) Issue: 3 Pages: e068223-e068223
- DOI
  10.1136/bmjopen-2022-068223
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08825, KAKENHI-PROJECT-21K16421, KAKENHI-PROJECT-23K15521
[Journal Article] Preoperative Osteopenia Is a Risk Factor for Death in Patients Undergoing Gastrectomy for Gastric Cancer2023
- Author(s)
  Shimizu S, Matsunaga T, Sawata S, Sakano YU, Makinoya M, Shishido Y, Miyatani K, Kono Y, Murakami Y, Hanaki T, Kihara K, Yamamoto M, Tokuyasu N, Takano S, Sakamoto T, Hasegawa T, Fujiwara Y.
- Journal Title
  
  Anticancer research
  
  Volume: 43 Issue: 8 Pages: 3665-3672
- DOI
  10.21873/anticanres.16548
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15521
[Journal Article] A low cumulative perioperative prognostic nutritional index predicts poor long-term outcomes in patients with gastric cancer: A single-center retrospective study in Japan2023
- Author(s)
  Miyatani K, Sakano Y, Makinoya M, Miyauchi W, Shimizu S, Shishido Y, Hanaki T, Kihara K, Matsunaga T, Yamamoto M, Tokuyasu N, Takano S, Sakamoto T, Hasegawa T, Saito H, Fujiwara Y.
- Journal Title
  
  Surgery Today
  
  Volume: 53 Issue: 11 Pages: 1294-1304
- DOI
  10.1007/s00595-023-02688-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K15521
[Journal Article] Hepatectomy for massive hepatic necrosis after transcatheter arterial embolization hemostasis for hepatic hemorrhage following hepatic trauma: A case report2023
- Author(s)
  Hanaki T, Tokuyasu N, Yata S, Kishino M, Murakami Y, Shishido Y, Miyatani K, Kihara K, Matsunaga T, Yamamoto M, Sakamoto T, Hasegawa T, Fujiwara Y.
- Journal Title
  
  Clinical Case Reports
  
  Volume: 11 Issue: 9
- DOI
  10.1002/ccr3.7888
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15521
[Journal Article] TYRO3 promotes chemoresistance via increased LC3 expression in pancreatic cancer2023
- Author(s)
  Hara Kazushi、Horikoshi Yosuke、Morimoto Masaki、Nakaso Kazuhiro、Sunaguchi Teppei、Kurashiki Tatsuyuki、Nakayama Yuji、Hanaki Takehiko、Yamamoto Manabu、Sakamoto Teruhisa、Fujiwara Yoshiyuki、Matsura Tatsuya
- Journal Title
  
  Translational Oncology
  
  Volume: 28 Pages: 101608-101608
- DOI
  10.1016/j.tranon.2022.101608
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06085, KAKENHI-PROJECT-23K15521, KAKENHI-PROJECT-22K16612
[Journal Article] Skeletal Muscle Mass Before Second-line Chemotherapy Correlates With Subsequent Prognosis and Rate of Late-line Chemotherapy in Patients With Unresectable Gastric Cancer2023
- Author(s)
  Matsunaga T, Satio H, Sakano YU, Makinoya M, Shimizu S, Shishido Y, Miyatani K, Kono Y, Murakami Y, Hanaki T, Kihara K, Yamamoto M, Tokuyasu N, Takano S, Sakamoto T, Hasegawa T, Fujiwara Y.
- Journal Title
  
  Anticancer research
  
  Volume: 43 Issue: 11 Pages: 5051-5059
- DOI
  10.21873/anticanres.16704
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15521
[Journal Article] High Glucose-stimulated aPKC Activation Promotes Pancreatic Cancer Cell Progression Through YAP Signaling2023
- Author(s)
  Sunaguchi T, Horikoshi Y, Hanaki T, Sakamoto T, Nakaso K, Sakai C, Yamashita K, Ohno S, Fujiwara Y, Matsura T.
- Journal Title
  
  Anticancer research
  
  Volume: 43 Issue: 11 Pages: 4843-4853
- DOI
  10.21873/anticanres.16681
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K15521, KAKENHI-PROJECT-22K10781
[Journal Article] The Significance of Surgical Intervention for Metasynchronous Liver Metastasis in Gastric Cancer: A Single-centre Analysis2022
- Author(s)
  Takehiko Hanaki, Teppei Sunaguchi, Keisuke Goto, Masaki Morimoto, Yuki Murakami, Yuji Shishido, Kozo Miyatani, Kyoichi Kihara, Tomoyuki Matsunaga, Manabu Yamamoto, Naruo Tokuyasu, Teruhisa Sakamoto, Toshimichi Hasegawa, Yoshiyuki Fujiwara
- Journal Title
  
  Anticancer Research
  
  Volume: 42(4) Issue: 4 Pages: 2177-2184
- DOI
  10.21873/anticanres.15700
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16421
[Journal Article] Ectopic liver on the surface of the gallbladder2022
- Author(s)
  Takehiko Hanaki, Kozo Miyatani
- Journal Title
  
  BMJ case reports.
  
  Volume: 15(6) Issue: 6 Pages: e251229-e251229
- DOI
  10.1136/bcr-2022-251229
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16421
[Journal Article] Surgical Administration of Indocyanine Green in Hepatectomy for Improved Bile Leakage Detection2022
- Author(s)
  Takehiko Hanaki, Keisuke Goto, Masaki Morimoto, et al.
- Journal Title
  
  Anticancer Res.
  
  Volume: 42(10) Issue: 10 Pages: 4787-4793
- DOI
  10.21873/anticanres.15983
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16421
[Journal Article] Laparoscopic cholecystectomy after percutaneous transhepatic gallbladder drainage for acute cholecystitis in a patient with a left ventricle assist device: a case report and brief review of the literature (with video)2022
- Author(s)
  Hanaki Takehiko、Sunaguchi Teppei、Goto Keisuke、Morimoto Masaki、Murakami Yuki、Tokuyasu Naruo、Takano Shuichi、Sakamoto Teruhisa、Hasegawa Toshimichi、Fujiwara Yoshiyuki
- Journal Title
  
  Clinical Case Report
  
  Volume: in press Issue: 5
- DOI
  10.1002/ccr3.5800
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16421
[Journal Article] Hepatectomy guided by indocyanine green fluorescent imaging for visualizing bile leakage (with video)2022
- Author(s)
  Takehiko Hanaki, Naruo Tokuyasu, Teruhisa Sakamoto, et al.
- Journal Title
  
  Clin Case Rep.
  
  Volume: 10(6) Issue: 6
- DOI
  10.1002/ccr3.5942
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16421
[Journal Article] Influence of the water jet system vs cavitron ultrasonic surgical aspirator for liver resection on the remnant liver2022
- Author(s)
  Takehiko Hanaki, Ayumi Tsuda, Teppei Sunaguchi, et al.
- Journal Title
  
  World J Clin Cases.
  
  Volume: 10(20) Issue: 20 Pages: 6855-6864
- DOI
  10.12998/wjcc.v10.i20.6855
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16421
[Journal Article] Cytoplasmic-only Expression of Maspin Predicts Unfavorable Prognosis in Patients With Pancreatic Ductal Adenocarcinoma2021
- Author(s)
  EI Uchinaka, Tomohiko Sakabe, Takehiko Hanaki, Naruo Tokuyasu, Teruhisa Sakamoto, Soichiro Honjo, Yoshiyuki Fujiwara, Yoshihisa Umekita
- Journal Title
  
  Anticancer Research
  
  Volume: 41(5) Issue: 5 Pages: 2543-2552
- DOI
  10.21873/anticanres.15032
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16421
[Journal Article] Human chromosome 3p21.3 carries TERT transcriptional regulators in pancreatic cancer.2021
- Author(s)
  Yagyu T, Ohira T, Shimizu R, Morimoto M, Murakami Y, Hanaki T, Kihara K, Matsunaga T, Yamamoto M, Tokuyasu N, Sakamoto T, Fujiwara Y, Kugoh H.
- Journal Title
  
  Scientific Reports
  
  Volume: 28;11(1):15355. Issue: 1 Pages: 15355-15355
- DOI
  10.1038/s41598-021-94711-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10086, KAKENHI-PROJECT-20K17688, KAKENHI-PROJECT-21K16421
[Journal Article] Successful Interventional Radiology for Acute Median Arcuate Ligament Syndrome After Pancreaticoduodenectomy2021
- Author(s)
  Takehiko Hanaki, Teruhisa Sakamoto, Shinsaku Yata, Yuki Murakami, Yoshiyuki Fujiwara
- Journal Title
  
  Cureus
  
  Volume: 13(2)
- DOI
  10.7759/cureus.13540
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16421
[Presentation] 肝切除におけるWater JetとCUSAの残存肝に対する影響の比較検討2023
- Author(s)
  花木武彦, 津田亜由美, 岸野幹也, 砂口天兵, 後藤圭佑, 河野友輔, 宍戸裕二, 村上裕樹, 宮谷幸造, 木原恭一, 松永知之, 山本学, 徳安成郎, 高野周一, 坂本照尚, 長谷川利路, 藤原義之
- Organizer
  日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-23K15521
[Presentation] ICGを用いた肝切除後胆汁漏出の術中リアルタイム検出についての私の工夫2023
- Author(s)
  花木武彦, 岸野幹也, 砂口天兵, 村上裕樹, 松永知之, 山本学, 徳安成郎, 坂本照尚, 藤原義之
- Organizer
  日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-23K15521
[Presentation] 高血糖によるaPKCの活性化はYAP/TAZシグナル経路を介し膵癌進展を促進する2022
- Author(s)
  砂口天兵、花木武彦、堀越洋輔、他
- Organizer
  第33回日本消化器癌発生学会総会
- Data Source
  KAKENHI-PROJECT-21K16421
[Presentation] ICG全身投与後の近赤外線観察による肝切除後胆汁漏出検出能の検討2021
- Author(s)
  花木武彦，砂口天兵，後藤圭佑，森本昌樹，村上裕樹，徳安成郎，高野周一，坂本照尚，長谷川利路，藤原義之
- Organizer
  第122回　日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-21K16421
[Presentation] 肝膿瘍を随伴し術前診断が困難であった胆管周囲嚢胞を伴った混合型肝癌の1例2021
- Author(s)
  花木武彦, 本城総一郎, 砂口天兵, 後藤圭佑, 森本昌樹, 村上裕樹, 徳安成郎, 坂本照尚, 長谷川利路, 藤原義之
- Organizer
  第57回日本胆道学会学術集会
- Data Source
  KAKENHI-PROJECT-21K16421
[Presentation] Successful interventional radiology for acute median arcuate ligament syndrome after pancreaticoduodenectomy2021
- Author(s)
  Takehiko Hanaki, Teruhisa Sakamoto, Keisuke Goto, Yuki Murakami, Naruo Tokuyasu, Soichiro Honjo, Yoshiyuki Fujiwara
- Organizer
  第33回　日本肝胆膵外科学会学術集会
- Data Source
  KAKENHI-PROJECT-21K16421

1. 徳安成郎 (40620919)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 土谷博之 (00403402)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 坂部友彦 (50639747)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 久郷裕之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 中山祐二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HANAKI Takehiko 花木 武彦

Research Projects

Research Products

Co-Researchers

膵癌Exosomal Tyro3を介した内皮間葉転換と膵癌進展機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肝細胞がんにおける新たな免疫回避メカニズムの解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

キチンナノファイバーのTGF-β/Smad経路を介した肝切後胆汁漏予防効果の検討

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Disruption of cell polarity signaling promotes pancreatic cancer progression via activation of the YAP/TAZ pathwayPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Right thoracoscopic resection in the supine position for recurrent pretracheal lymph nodes after esophagectomy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Preoperative Osteopenia as Risk Factor for Death from Other Diseases After Gastrectomy in Elderly Patients2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Current Value of Perioperative Therapies for Resectable or Borderline Resectable Pancreatic Cancer2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Evaluation of perioperative D-dimer concentration for predicting postoperative deep vein thrombosis following hepatobiliary-pancreatic surgery2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Surgical Outcomes of Robotic Distal Pancreatectomy Versus Laparoscopic Distal Pancreatectomy at a Hospital in a Sparsely Populated Area2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Impact of Robot-Assisted Minimally Invasive Esophagectomy for Esophageal Cancer: A Propensity Score-Matched Short-Term Analysis2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Prognostic significance of the cachexia index in patients with unresectable advanced gastric cancer receiving palliative chemotherapy: a retrospective single-center study2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Efficacy of indocyanine green systemic administration for bile leak detection after hepatectomy: a protocol for a prospective single-arm clinical trial with a historical control group2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Preoperative Osteopenia Is a Risk Factor for Death in Patients Undergoing Gastrectomy for Gastric Cancer2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A low cumulative perioperative prognostic nutritional index predicts poor long-term outcomes in patients with gastric cancer: A single-center retrospective study in Japan2023

HANAKI Takehiko 花木武彦