Nagai Makoto 永井諒

… Alternative Names

NAGAI MAKOTO 永井諒

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Researcher Number	30791545
Other IDs
Affiliation (Current)	2025: 兵庫医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2022: 兵庫医科大学, 医学部, 講師 2020 – 2021: 兵庫医科大学, 医学部, 助教 2016 – 2018: 兵庫医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 53050:Dermatology-related / Dermatology Except Principal Investigator Dermatology
Keywords	Principal Investigator アトピー性皮膚炎 / IL-33 / ILC2 / 2型自然リンパ球 / ILC２ / ２型自然リンパ球 / 好塩基球 / basophil Except Principal Investigator アトピー性皮膚炎 / 遺伝子変異 … More / 掌蹠角化症 / 魚鱗癬 / IL-33 / 抗菌ペプチド / サイトカイン / トランスグルタミナーゼ / 自然免疫 / 角化症 Less

Study on the migration capacity of type 2 innate lymphocytes in inflammatory skin diseasesPrincipal Investigator
- Principal Investigator
  
  Nagai Makoto
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Hyogo Medical University
IL-33R(+) cells and atopic dermatitisPrincipal Investigator
- Principal Investigator
  
  NAGAI Makoto
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Hyogo Medical University
The induction of alarmins in keratinization disorders
- Principal Investigator
  
  Yamanishi Kiyofumi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Hyogo Medical University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] IL-33-induced keratoconjunctivitis is mediated by group 2 innate lymphoid cells in mice2023
- Author(s)
  Hosotani Y, Yasuda K, Nagai M, Yamanishi K, Kanazawa N, Gomi Fumi, Imai Y
- Journal Title
  
  Allergol. Int.
  
  Volume: 72 Issue: 2 Pages: 324-331
- DOI
  10.1016/j.alit.2022.10.003
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08337, KAKENHI-PROJECT-20K17331, KAKENHI-PROJECT-21K08313, KAKENHI-PROJECT-23K06521
[Journal Article] Evaluation of long-term disease control with dupilumab therapy using the Atopic Dermatitis Control Tool in real-world clinical practice2022
- Author(s)
  Kunimoto M, Imai Y*, Matsutani M, Nakatani-Kusakabe M, Nagai M, Natsuaki M, Yamanishi K, Kanazawa N
- Journal Title
  
  J Cutan Immunol Allergy
  
  Volume: 5 Issue: 2 Pages: 69-71
- DOI
  10.1002/cia2.12212
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08337, KAKENHI-PROJECT-20K17331, KAKENHI-PROJECT-21K08313
[Journal Article] Dupilumab treatment reduces serum SCCA2 levels in patients with atopic dermatitis2022
- Author(s)
  Kita Kanako、Imai Yasutomo、Nagai Makoto、Natsuaki Masaru、Kanazawa Nobuo
- Journal Title
  
  Journal of Cutaneous Immunology and Allergy
  
  Volume: - Issue: 3 Pages: 1-2
- DOI
  10.1002/cia2.12282
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17331
[Journal Article] Switching to ixekizumab improves adalimumab‐induced interstitial lung disease in patients with psoriatic arthritis: A case report2021
- Author(s)
  Hayashi H, Kusakabe M, Nagai M, Imai Y, Yamanishi K
- Journal Title
  
  J Cutan Immunol Allergy
  
  Volume: 4 Issue: 1 Pages: 22-23
- DOI
  10.1002/cia2.12146
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17331, KAKENHI-PROJECT-18K08284
[Journal Article] Dupilumab effects on innate lymphoid cell and Th cell populations in patients with atopic dermatitis2021
- Author(s)
  Imai Y, Kusakabe M, Nagai M, Yasuda K, Yamanishi K.
- Journal Title
  
  JID Innovations
  
  Volume: 1 Issue: 1 Pages: 100003-100003
- DOI
  10.1016/j.xjidi.2021.100003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17331, KAKENHI-PROJECT-18K08284, KAKENHI-PROJECT-20K07469
[Journal Article] Monitoring Cellular Movement with Photoconvertible Fluorescent Protein and Single-Cell RNA Sequencing Reveals Cutaneous Group 2 Innate Lymphoid Cell Subtypes, Circulating ILC2 and Skin-Resident ILC22021
- Author(s)
  Nakatani-Kusakabe Minori、Yasuda Koubun、Tomura Michio、Nagai Makoto、Yamanishi Kiyofumi、Kuroda Etsushi、Kanazawa Nobuo、Imai Yasutomo
- Journal Title
  
  JID Innovations
  
  Volume: 1 Issue: 3 Pages: 100035-100035
- DOI
  10.1016/j.xjidi.2021.100035
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07469, KAKENHI-PROJECT-21K08337, KAKENHI-PROJECT-20K17331
[Journal Article] レボフロキサシンによるアナフィラキシーの1例2020
- Author(s)
  藤本真由, 夏秋優, 北佳奈子, 井上裕香子, 永井諒, 今井康友, 山西清文
- Journal Title
  
  皮膚の科学
  
  Volume: 19 Pages: 244-250
- NAID
  130008006031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17331
[Journal Article] IL-33-induced atopic dermatitis-like inflammation in mice is mediated by group 2 innate lymphoid cells in concert with basophils2019
- Author(s)
  Imai Y, Yasuda K, Nagai M, Kusakabe M, Kubo M, Nakanishi K,Yamanishi K
- Journal Title
  
  J Investig Dermatol
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16356
[Journal Article] Japanese case of Bothnian-type palmoplantar keratoderma with a novel missense mutation of p.Trp35Ser in extracellular loop A of aquaporin-52019
- Author(s)
  Wada Yoshihiro、Kusakabe Minori、Nagai Makoto、Imai Yasutomo、Yamanishi Kiyofumi
- Journal Title
  
  The Journal of Dermatology
  
  Volume: 46 Issue: 3
- DOI
  10.1111/1346-8138.14621
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10219, KAKENHI-PROJECT-17K16356
[Journal Article] Serum procalcitonin and presepsin levels in patients with generalized pustular psoriasis2018
- Author(s)
  Nagai M, Imai Y*, Wada Y, Kusakabe M, Yamanishi K
- Journal Title
  
  Dis Markers
  
  Volume: - Pages: 1-6
- DOI
  10.1155/2018/9758473
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16356, KAKENHI-PROJECT-18K08284
[Journal Article] A Japanese case of ichthyosiform erythroderma with a novel mutation in NIPAL4/Ichthyin2017
- Author(s)
  Kusakabe M, Nagai M, Nakano E, Jitsukawa O, Nishigori C, Yamanishi K.
- Journal Title
  
  Acta Derm Venereol
  
  Volume: 97 Issue: 3 Pages: 397-398
- DOI
  10.2340/00015555-2550
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461668
[Journal Article] A mild case of congenital ichthyosiform erythroderma with periodic exacerbation: Novel mutations in ABCA12 and up-regulation of calprotectin in the epidermis2017
- Author(s)
  Wada Y, Kusakabe M, Nagai M, Yamamoto M, Imai Y, Ide YH, Hirota S, Yamanishi K
- Journal Title
  
  J Dermatol
  
  Volume: 44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16356
[Journal Article] Expression of IL-33 in ocular surface epithelium induces atopic keratoconjunctivitis with activation of group 2 innate lymphoid cells in mice2017
- Author(s)
  Imai Yasutomo、Hosotani Yuka、Ishikawa Hiroto、Yasuda Koubun、Nagai Makoto、Jitsukawa Orie、Gomi Fumi、Nakanishi Kenji、Yoshimoto Tomohiro、Nakamura Takahiro、Yamanishi Kiyofumi
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 10053-10053
- DOI
  10.1038/s41598-017-10227-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08813, KAKENHI-PROJECT-17K11487, KAKENHI-PROJECT-17K16356, KAKENHI-PROJECT-15K09796, KAKENHI-PROJECT-17K19575
[Journal Article] Lamellar ichthyosis with pseudoexon activation in the transglutaminase 1 gene2015
- Author(s)
  Suga Y, Tsuda T, Nagai M, Sakaguchi Y, Jitsukawa O, Yamamoto M, Hitomi K, Yamanishi K.
- Journal Title
  
  J Dermatol
  
  Volume: 印刷中 Issue: 6 Pages: 642-645
- DOI
  10.1111/1346-8138.12846
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461668
[Presentation] Identification of serum biomarkers predicting the therapeutic effect of dupilumab in atopic dermatitis by a targeted metabolomics approach2021
- Author(s)
  Miyamoto Shoko, Nishiumi Shin, Matsutani Masako, Nagai Makoto, Yamanishi Kiyofumi, Kanazawa Nobuo, Imai Yasutomo
- Organizer
  The 46th Annual Meeting of the Japanese Society for Investigative Dermatology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17331
[Presentation] Dupilumab’s Effects on Circulating Group 2 Innate Lymphoid Cell and T Helper Type 2 Cell Populations in Patients with Atopic Dermatitis2020
- Author(s)
  Imai Y, Kusakabe M, Nagai M, Inoue Y, Natsuaki M, Yamanishi K
- Organizer
  The 45th Annual Meeting of the Japanese Society for Investigative Dermatology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17331
[Presentation] Single-Cell RNA Sequencing Reveals Novel Cutaneous Group 2 Innate Lymphoid Cell Subtypes, Circulating ILC2, and Skin-Resident ILC22020
- Author(s)
  Kusakabe M, Imai Y, Nagai M, Yasuda K, Kuroda E, Tomura M, Yamanishi K
- Organizer
  The 45th Annual Meeting of the Japanese Society for Investigative Dermatology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17331
[Presentation] 膿疱性乾癬の実臨床で有用な疾患活動性マーカー探索の試み2018
- Author(s)
  永井諒, 今井康友, 山西清文
- Organizer
  第３３回日本乾癬学会学術大会
- Data Source
  KAKENHI-PROJECT-17K16356
[Presentation] 子宮体癌の転移性鼠径ヘルニア嚢腫瘍の1例2017
- Author(s)
  羽田孝司, 永井諒, 和田吉弘, 伊藤孝明, 山西清文, 鍔本浩志
- Organizer
  第33回日本皮膚悪性腫瘍学会学術大会
- Data Source
  KAKENHI-PROJECT-17K16356
[Presentation] Depletion of basophils alleviates ILC2-dependent atopic dermatitis-like inflammation in mice overexpressing interleukin-33 in the skin2017
- Author(s)
  Imai Yasutomo, Nagai Makoto, Yamamoto Masaaki, Yasuda Koubun, Nakanishi Kenji, Yoshimoto Tomohiro, Yamanishi Kiyofumi
- Organizer
  The 42th Annual Meeting of the Japanese Society for Investigative Dermatology (JSID2017)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16356
[Presentation] ムシ咬傷後に生じた片側性Beau’s linesの1例2017
- Author(s)
  草壁みのり, 今井康友, 永井諒, 山西清文
- Organizer
  第461回日本皮膚科学会大阪地方会
- Data Source
  KAKENHI-PROJECT-17K16356
[Presentation] ブロメライン軟膏によるアナフィラキシーショックの一例2017
- Author(s)
  和田吉弘, 山本雅章, 永井諒, 今井康友, 夏秋優,山西清文
- Organizer
  第47回日本皮膚アレルギー・接触皮膚学会総会学術大会
- Data Source
  KAKENHI-PROJECT-17K16356
[Presentation] 表皮カルプロテクチンの発現誘導を伴う新規ABCA12変異による軽症型魚鱗癬様紅皮症2017
- Author(s)
  和田吉弘, 草壁みのり, 永井諒, 山本雅章, 今井康友, 山西清文
- Organizer
  116回日本皮膚科学会総会
- Data Source
  KAKENHI-PROJECT-17K16356
[Presentation] アトピー性角結膜炎モデルとしてのIL-33過剰産生遺伝子改変マウス（hK14-IL-33Tg）の有用性2017
- Author(s)
  細谷友雅, 今井康友, 石川裕人, 安田好文, 永井諒, 實川織江, 中西憲司, 善本知広, 中村隆宏，山西清文, 五味文
- Organizer
  第121回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-17K16356
[Presentation] 局所麻酔とTLA法を用いたhigh risk症例における全身麻酔回避2017
- Author(s)
  永井諒, 中川登, 和田吉弘, 山本雅章, 伊藤孝明, 山西清文
- Organizer
  32回日本皮膚外科学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17K16356
[Presentation] Atopic keratoconjunctivitis spontaneously develop in a mouse model of atopic dermatitis expressing the mouse interleukin-33 gene driven by a keratin 14 promoter.2017
- Author(s)
  Imai Yasutomo, Hosotani Yuka, Kusakabe Minori, Yasuda Koubun, Nagai Makoto, Gomi Fumi, Nakanishi Kenji, Yoshimoto Tomohiro, Nakamura Takahiro, Yamanishi Kiyofumi.
- Organizer
  第76回米国研究皮膚科学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16356
[Presentation] 顆粒球吸着療法で加療した疱疹状膿痂疹の一例2017
- Author(s)
  和田吉弘, 山本雅章, 永井諒, 今井康友, 山西清文
- Organizer
  第32回日本乾癬学会学術大会
- Data Source
  KAKENHI-PROJECT-17K16356
[Presentation] 手指に腫瘤を形成した CD8陽性成人T細胞白血病/リンパ腫の1例2017
- Author(s)
  尼木麻実, 今井康友, 永井諒, 山西清文
- Organizer
  第465回日本皮膚科学会大阪地方会
- Data Source
  KAKENHI-PROJECT-17K16356
[Presentation] 角結膜上皮の過剰なIL-33はアトピー性角結膜炎を誘導する2017
- Author(s)
  今井康友, 細谷友雅, 石川裕人, 安田好文, 永井諒，實川織江, 五味文, 中西憲司, 善本知広, 中村隆宏, 山西清文
- Organizer
  第66回日本アレルギー学会
- Data Source
  KAKENHI-PROJECT-17K16356
[Presentation] A Japanese case of variable ichthyosiform erythroderma with a novel NIPAL4 mutation identified by whole exome sequencing2016
- Author(s)
  Kusakabe M, Nagai M, Nakano E, Jitsukawa O, Nishigori C, Yamanishi K.
- Organizer
  The 4th Eastern Asia Dermatology Congress
- Place of Presentation
  東京ベイ舞浜ホテルクラブリゾート（千葉県浦安市）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461668

1. IMAI YASUTOMO (10529514)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
2. Yamanishi Kiyofumi (10182586)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
3. YAMAMOTO MASAAKI (60624640)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. HANEDA TAKASHI (90580035)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. SAKAGUCHI YOSHIKO

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. JITSUKAWA ORIE

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. YASUDA Koubun

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
8. 金澤伸雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nagai Makoto 永井 諒

NAGAI MAKOTO 永井 諒

Research Projects

Research Products

Co-Researchers

Study on the migration capacity of type 2 innate lymphocytes in inflammatory skin diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

IL-33R(+) cells and atopic dermatitisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The induction of alarmins in keratinization disorders

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] IL-33-induced keratoconjunctivitis is mediated by group 2 innate lymphoid cells in mice2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Evaluation of long-term disease control with dupilumab therapy using the Atopic Dermatitis Control Tool in real-world clinical practice2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dupilumab treatment reduces serum SCCA2 levels in patients with atopic dermatitis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Switching to ixekizumab improves adalimumab‐induced interstitial lung disease in patients with psoriatic arthritis: A case report2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dupilumab effects on innate lymphoid cell and Th cell populations in patients with atopic dermatitis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Monitoring Cellular Movement with Photoconvertible Fluorescent Protein and Single-Cell RNA Sequencing Reveals Cutaneous Group 2 Innate Lymphoid Cell Subtypes, Circulating ILC2 and Skin-Resident ILC22021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] レボフロキサシンによるアナフ ィラキシーの1例2020

Author(s)

Journal Title

NAID

Data Source

[Journal Article] IL-33-induced atopic dermatitis-like inflammation in mice is mediated by group 2 innate lymphoid cells in concert with basophils2019

Author(s)

Journal Title

Data Source

[Journal Article] Japanese case of Bothnian-type palmoplantar keratoderma with a novel missense mutation of p.Trp35Ser in extracellular loop A of aquaporin-52019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Serum procalcitonin and presepsin levels in patients with generalized pustular psoriasis2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Japanese case of ichthyosiform erythroderma with a novel mutation in NIPAL4/Ichthyin2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A mild case of congenital ichthyosiform erythroderma with periodic exacerbation: Novel mutations in ABCA12 and up-regulation of calprotectin in the epidermis2017

Nagai Makoto 永井諒

NAGAI MAKOTO 永井諒

[Journal Article] レボフロキサシンによるアナフィラキシーの1例2020