Maruyama Emi 丸山恵美

Researcher Number	30792072
Other IDs
Affiliation (Current)	2025: 川崎医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2023 – 2024: 川崎医科大学, 医学部, 講師 2017 – 2022: 川崎医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 52030:Psychiatry-related Except Principal Investigator Basic Section 59010:Rehabilitation science-related / Rehabilitation science/Welfare engineering / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Psychiatric science
Keywords	Principal Investigator ECS / RyRs / 海馬 / Ca2+ / リアノジン受容体 / 電気けいれん療法 / うつ / 小胞体 / ECT / IP3受容体 / ダントロレン … More Except Principal Investigator … More リハビリテーション / 運動療法 / 皮質脊髄路 / 脳梗塞 / マイオカイン / 神経栄養因子 / 海馬 / myokine / 血中乳酸濃度 / 乳酸 / 空間記憶能 / 時間依存性 / 神経再生 / 筋刺激 / 脊髄再生 / 運動機能回復 / フルオロゴールド / 皮質脊髄路再生 / ANA-12 / TrkB / BDNF / 軸索再生 / 電気刺激 / 骨格筋収縮 / 脊髄損傷 / うつ病 / ECT / Ca2+ / ECS / マウス / イノシトール三リン酸受容体 / リアノジン受容体 / カルシウムシグナル系 / うつ様モデル / ストレス / 電気けいれん療法 / 神経科学 / 脳神経疾患 / 生理学 / 再生医学 / 電気生理 / シナプス Less

全身運動が脳神経系疾患後の機能障害を低減させる機序の解明～マイオカインに着目して
- Principal Investigator
  
  氷見直之
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Kawasaki Medical School
うつ状態におけるリアノジン受容体の変化と電気けいれん療法の抗うつ効果との関係Principal Investigator
- Principal Investigator
  
  丸山恵美
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Kawasaki Medical School
脳梗塞後リハビリテーションによる大脳基底核経路ネットワーク改変メカニズムの解明
- Principal Investigator
  
  岡部直彦
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Kawasaki Medical School
The effects of exercise on the dynamics of blood lactate and myokines
- Principal Investigator
  
  Himi Naoyuki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Kawasaki Medical School
Mechanisms in motro recovery aftre spina cord injury by electrical stimulation induced muscle contraction
- Principal Investigator
  
  MIYAMOTO OSAMU
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Kawasaki Medical School
Elucidation of the pathogenic mechanism of depression - involvement of ryanodine receptors and IP3 receptor.Principal Investigator
- Principal Investigator
  
  Maruyama Emi
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Kawasaki Medical School
The molecular mechanism underlying time-dependency of post-stroke rehabilitation
- Principal Investigator
  
  岡部直彦
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Kawasaki Medical School
The effects of rehabilitation on activity of hippocampal neurons – electrophysiological study
- Principal Investigator
  
  Himi Naoyuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Kawasaki Medical School
The mechanism of axonal remodeling in corticospinal tract induced by task specific rehabilitative training after stroke
- Principal Investigator
  
  岡部直彦
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Kawasaki Medical School
The mechanism of electroconvulsive therapy-the involvement of intracellular Ca2+ signaling
- Principal Investigator
  
  Miyamoto Osamu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Kawasaki Medical School

All 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Ryanodine receptors are involved in the improvement of depression-like behaviors through electroconvulsive shock in stressed mice.2021
- Author(s)
  91.Nakamura-Maruyama E, Kai R, Himi N, Okabe N, Narita K, Miyazaki T, Aoki S, Miyamoto O
- Journal Title
  
  Brain Stimulation
  
  Volume: 14 Issue: 1 Pages: 36-47
- DOI
  10.1016/j.brs.2020.11.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15500
[Journal Article] The protective effect and mechanism of COA-Cl in acute phase after spinal cord injury2021
- Author(s)
  Sakamoto I, Himi N, Hayashi N, Okabe N, Nakamura-Maruyama E, Tsukamoto I, Hasegawa T, Miyamoto O.
- Journal Title
  
  Neuroscience Research
  
  Volume: - Pages: 114-121
- DOI
  10.1016/j.neures.2020.10.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K10804
[Journal Article] 新規核酸アナログCOA-Clによる脊髄損傷後の血管新生および機能回復効果2020
- Author(s)
  坂本一晴、氷見直之、中村ー丸山恵美、萩原喜美子、林範人、長谷川徹、宮本修
- Journal Title
  
  川崎医学会誌
  
  Volume: 46 Pages: 65-72
- NAID
  120007000149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K10804
[Journal Article] Very Early Initiation Reduces Benefits of Poststroke Rehabilitation Despite Increased Corticospinal Projections2019
- Author(s)
  Okabe Naohiko、Himi Naoyuki、Nakamura-Maruyama Emi、Hayashi Norito、Sakamoto Issei、Hasegawa Toru、Miyamoto Osamu
- Journal Title
  
  Neurorehabilitation and Neural Repair
  
  Volume: 33 Issue: 7 Pages: 538-552
- DOI
  10.1177/1545968319850132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K01493, KAKENHI-PROJECT-18KK0276
[Journal Article] Improvement of motor function induced by skeletal muscle contraction in spinal cord-injured rats2019
- Author(s)
  Hayashi N, Himi N, Nakamura-Maruyama E, Okabe N, Sakamoto I, Hasegawa T, Miyamoto O
- Journal Title
  
  Spine J
  
  Volume: in press Issue: 6 Pages: 1094-1105
- DOI
  10.1016/j.spinee.2018.12.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K10804
[Journal Article] Constraint-induced movement therapy improves efficacy of taskspecific training after severe cortical stroke depending on the ipsilesional corticospinal projections2018
- Author(s)
  Naohiko Okabe, Naoyuki Himi, Emi Nakamura-Maruyama, Norito Hayashi, Issei Sakamoto, Kazuhiko Narita, Toru Hasegawa, Osamu Miyamoto
- Journal Title
  
  Experimental Neurology
  
  Volume: in press Pages: 108-120
- DOI
  10.1016/j.expneurol.2018.04.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K01493, KAKENHI-PROJECT-18K10804
[Journal Article] The involement of ryanodine receptors in depression-like model mouse2018
- Author(s)
  Nakamura-Maruyama E, Ishikawa R, Himi N, Okabe N, Narita K, Miyazaki T, Aoki S, Miyamoto O
- Journal Title
  
  The Journal of Physiological Sciences
  
  Volume: 68
- Data Source
  KAKENHI-PROJECT-15K09846
[Journal Article] The Role of Endogenous Neurogenesis in Functional Recovery and Motor Map Reorganization Induced by Rehabilitative Therapy after Stroke in Rats.2017
- Author(s)
  Shiromoto Takashi, Okabe N, Lu F, Maruyama-Nakamura E, Himi N, Narita K, Yagita Yoshiki, Kimira K, Miyamoto O
- Journal Title
  
  Journal of Stroke and Cerebrovascular Diseases
  
  Volume: 26 Pages: 260-272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09846
[Journal Article] Rehabilitative skilled forelimb training enhances axonal remodeling in the corticospinal pathway but not the brainstem-spinal pathways after photothrombotic stroke in the primary motor cortex2017
- Author(s)
  Okabe Naohiko、Himi Naoyuki、Maruyama-Nakamura Emi、Hayashi Norito、Narita Kazuhiko、Miyamoto Osamu
- Journal Title
  
  PLOS ONE
  
  Volume: 12 Issue: 11 Pages: 0187413-0187413
- DOI
  10.1371/journal.pone.0187413
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K01493
[Journal Article] Ryanodine receptors contribute to the induction of ischemic tolerance.2016
- Author(s)
  Nakamura-Maruyama E, Miyamoto O, Okabe N, Himi N, Feng L, Narita K, Keep RF, Yamamoto T, Nakamura T
- Journal Title
  
  Brain Research Bulletin
  
  Volume: 122 Pages: 45-53
- DOI
  10.1016/j.brainresbull.2016.02.018
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09846, KAKENHI-PROJECT-25460059, KAKENHI-PROJECT-15K16382, KAKENHI-PROJECT-16K08237
[Presentation] 運動療法の種類によるマイオカイン類の分泌への影響2022
- Author(s)
  氷見直之、中村-丸山恵美、中村丈洋
- Organizer
  第100回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-20K11175
[Presentation] The characteristics of Ca2+ release via ryanodine receptors are altered in the hippocampus of depression-like model mice.2022
- Author(s)
  Emi Nakamura-Maruyama, Naoyuki Himi, Kazuhiko Narita, Risa Kai, Osamu Miyamoto
- Organizer
  第98回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-18K15500
[Presentation] The characteristics of Ca2+ release via ryanodine receptors are altered in the hippocampus of depression-like model mice.2021
- Author(s)
  Emi Nakamura-Maruyama, Naoyuki Himi, Kazuhiko Narita, Risa Kai, Osamu Miyamoto
- Organizer
  第126回日本解剖学会総会・全国学術集会／第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-18K15500
[Presentation] ECSによってリアノジン受容体を介したCa2+放出は変化する。2020
- Author(s)
  中村(丸山)恵美、氷見直之、成田和彦、甲斐里沙、岡部直彦、宮本修
- Organizer
  第50 回日本神経精神薬理学会年会第42 回日本生物学的精神医学会年会第4 回日本精神薬学会総会・学術集会（NPBPPP 合同年会）
- Data Source
  KAKENHI-PROJECT-18K15500
[Presentation] Alteration of Ca2+ release via ryanodine receptors in the hippocampus of depression-like model mice.2020
- Author(s)
  Emi Nakamura-Maruyama, Naoyuki Himi, Kazuhiko Narita, Risa Kai, Naohiko Okabe, Osamu Miyamoto.
- Organizer
  第97回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-18K15500
[Presentation] Characteristics and functions of cerebral hypoperfusion model rats by microsphere embolism.2019
- Author(s)
  Naoyuki Himi、Naohiko Okabe、Hisashi Takahashi、Emi Nakamura-Maruyama、Norito Hayashi, Issei Sakamoto, Tomoshige Koga, Osamu Miyamoto
- Organizer
  第42回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17K01492
[Presentation] Improvement of motor function induced by muscle contraction in spinal cord injury rats2019
- Author(s)
  Hayashi N, Himi N, Maruyama E, Okabe N, Sakamoto I, Hasegawa T, Miyamoto O
- Organizer
  NASS（北米脊椎学会）2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K10804
[Presentation] Improvement of motor function induced by skeletal muscle contraction in spinal cord injury rats2019
- Author(s)
  Hayashi N, Himi N, Nakamura-Maruyama E, Okabe N, Sakamoto I, Hasegawa T, Miyamoto O
- Organizer
  9th Federation of the Asian Oceanian Physiological Societies Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K10804
[Presentation] 脳梗塞後リハビリテーションによる神経回路再編：リハビリテーション治療の可能性と限界2018
- Author(s)
  岡部直彦、氷見直之、中村丸山恵美、成田和彦、宮本修
- Organizer
  第９５回日本生理学会
- Data Source
  KAKENHI-PROJECT-17K01493
[Presentation] うつ様モデルマウスにおけるECSの効果に対するリアノジン受容体の関与。2018
- Author(s)
  中村-丸山恵美、甲斐里沙、氷見直之、岡部直彦、成田和彦、宮崎哲治、青木省三、宮本修
- Organizer
  第28回日本臨床精神神経薬理学会・第48回日本神経精神薬理学会合同年会
- Data Source
  KAKENHI-PROJECT-18K15500
[Presentation] Constraint-induced movement therapy improves efficacy of task-specific training after severe cortical stroke depending on the ipsilesional corticospinal projections2018
- Author(s)
  Okabe N, Himi N, Nakamura-Maruyama E, Miyamoto O
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-18K10804
[Presentation] 脳梗塞後リハビリテーションによる下降性脊髄路の変化2017
- Author(s)
  岡部直彦、氷見直之、中村丸山恵美、成田和彦、宮本修
- Organizer
  第４０回日本神経科学回
- Data Source
  KAKENHI-PROJECT-17K01493
[Presentation] うつ様モデルマウスにおけるCa2+シグナル経路―リアノジン受容体に対するECTの効果2017
- Author(s)
  丸山恵美、石川里沙、氷見直之、岡部直彦、成田和彦、宮本修
- Organizer
  第94回日本生理学会
- Place of Presentation
  アクトシティ浜松（浜松市）
- Year and Date
  2017-03-30
- Data Source
  KAKENHI-PROJECT-15K09846
[Presentation] 運動習慣による海馬BDNFの上昇は脳虚血発症による記憶障害を予防する2016
- Author(s)
  氷見直之, 岡部直彦, 丸山恵美, 陸豊, 城本高志, 高橋尚, 成田和彦, 古我知成, 宮本修
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-07-22
- Data Source
  KAKENHI-PROJECT-15K09846

1. Himi Naoyuki (70412161)

# of Collaborated Projects: 8 results

# of Collaborated Products: 18 results
2. Miyamoto Osamu (00253287)

# of Collaborated Projects: 7 results

# of Collaborated Products: 17 results
3. 岡部直彦 (30614276)

# of Collaborated Projects: 5 results

# of Collaborated Products: 11 results
4. 陸豊 (20708557)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 宮崎哲治 (50412185)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 佐々木崇了 (10461253)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 矢作綾野 (10584873)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 西松伸一郎 (20222185)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 氏原嘉洋 (80610021)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 中村丈洋 (80419506)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NARITA Kazuhiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
12. SHIROMOTO Takashi

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

Maruyama Emi 丸山 恵美

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うつ状態におけるリアノジン受容体の変化と電気けいれん療法の抗うつ効果との関係Principal Investigator

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Elucidation of the pathogenic mechanism of depression - involvement of ryanodine receptors and IP3 receptor.Principal Investigator

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[Journal Article] Ryanodine receptors are involved in the improvement of depression-like behaviors through electroconvulsive shock in stressed mice.2021

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[Journal Article] The protective effect and mechanism of COA-Cl in acute phase after spinal cord injury2021

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[Journal Article] 新規核酸アナログCOA-Clによる脊髄損傷後の血管新生および機能回復効果2020

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NAID

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[Journal Article] Very Early Initiation Reduces Benefits of Poststroke Rehabilitation Despite Increased Corticospinal Projections2019

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[Journal Article] Improvement of motor function induced by skeletal muscle contraction in spinal cord-injured rats2019

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Maruyama Emi 丸山恵美

[Presentation] 脳梗塞後リハビリテーションによる神経回路再編：リハビリテーション治療の可能性と限界2018