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Minaga Kosuke  三長 孝輔

ORCIDConnect your ORCID iD *help
Researcher Number 30793814
Other IDs
Affiliation (Current) 2025: 近畿大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2021 – 2023: 近畿大学, 医学部, 講師
2020: 近畿大学, 大学病院, 医学部講師
2019 – 2020: 近畿大学, 大学病院, 助教
Review Section/Research Field
Principal Investigator
Basic Section 53010:Gastroenterology-related
Keywords
Principal Investigator
腸内細菌叢 / 腸内細菌 / Dysbiosis / IgG4関連疾患 / 形質細胞様樹状細胞 / 自己免疫性膵炎 / 自然免疫 / 細菌叢 / 口腔内細菌 / 細菌叢プロファイル … More / 腸管バリア機能 / Leaky Gut Syndrome / タイトジャンクション蛋白質 / 高脂肪食 / I型インターフェロン / 肥満 / 生活習慣病 / Toll様受容体 / Akkermansia muciniphila / 自然免疫反応 / 慢性膵炎 Less
  • Research Projects

    (3 results)
  • Research Products

    (25 results)
  • Co-Researchers

    (2 People)
  •  Mechanism of multi-organ involvements in IgG4-related disease from the view of microbiome profilePrincipal Investigator

    • Principal Investigator
      三長 孝輔
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Kindai University
  •  The role of lifestyle-induced intestinal barrier dysfunction in the pathogenesis of autoimmune pancreatitisPrincipal Investigator

    • Principal Investigator
      Minaga Kosuke
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Kindai University
  •  Identification of gut microbiota that regulates the development of chronic pancreatitisPrincipal Investigator

    • Principal Investigator
      Minaga Kosuke
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Kindai University

All 2023 2022 2021 2020 2019

All Journal Article Presentation

  • [Journal Article] 【常在微生物叢の異常から自己免疫疾患を読み解く】自己免疫性膵炎/IgG4関連疾患の発症に腸内細菌の乱れが関与する2023

    • Author(s)
      三長孝輔、渡邉智裕
    • Journal Title

      Microbiome Science

      Volume: 2 Pages: 159-165

    • Data Source
      KAKENHI-PROJECT-23K07450
  • [Journal Article] A Mouse Model of Acute and Chronic Pancreatitis2022

    • Author(s)
      Minaga Kosuke、Watanabe Tomohiro、Kamata Ken、Kudo Masatoshi、Strober Warren
    • Journal Title

      Current Protocols in Immunology

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K15987
  • [Journal Article] Pancreatic colonization of fungi in the development of severe acute pancreatitis2022

    • Author(s)
      Otsuka Yasuo、Kamata Ken、Minaga Kosuke、Watanabe Tomohiro、Kudo Masatoshi
    • Journal Title

      Frontiers in Cellular and Infection Microbiology

      Volume: 12 Pages: 1-7

    • DOI

      10.3389/fcimb.2022.940532

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K15987
  • [Journal Article] A Mouse Model of Acute and Chronic Pancreatitis2022

    • Author(s)
      Minaga Kosuke、Watanabe Tomohiro、Kamata Ken、Kudo Masatoshi、Strober Warren
    • Journal Title

      Current Protocols

      Volume: 2 Issue: 4

    • DOI

      10.1002/cpz1.422

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K15987
  • [Journal Article] Disruption of the intestinal barrier exacerbates experimental autoimmune pancreatitis by promoting the translocation of <i>Staphylococcus sciuri</i> into the pancreas2022

    • Author(s)
      Yoshikawa Tomoe、Minaga Kosuke、Hara Akane、Sekai Ikue、Kurimoto Masayuki、Masuta Yasuhiro、Otsuka Yasuo、Takada Ryutaro、Kamata Ken、Park Ah-Mee、Takamura Shiki、Kudo Masatoshi、Watanabe Tomohiro
    • Journal Title

      International Immunology

      Volume: 34 Issue: 12 Pages: 621-634

    • DOI

      10.1093/intimm/dxac039

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K07996, KAKENHI-PROJECT-20K07556, KAKENHI-PROJECT-21K15987
  • [Journal Article] High-fat diet aggravates experimental autoimmune pancreatitis through the activation of type I interferon signaling pathways2022

    • Author(s)
      Sekai Ikue、Minaga Kosuke、Hara Akane、Otsuka Yasuo、Kurimoto Masayuki、Omaru Naoya、Okai Natsuki、Masuta Yasuhiro、Takada Ryutaro、Yoshikawa Tomoe、Kamata Ken、Kudo Masatoshi、Watanabe Tomohiro
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 637 Pages: 189-195

    • DOI

      10.1016/j.bbrc.2022.11.030

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07996, KAKENHI-PROJECT-21K15987
  • [Journal Article] IL-33 as a Critical Cytokine for Inflammation and Fibrosis in Inflammatory Bowel Diseases and Pancreatitis2021

    • Author(s)
      Kurimoto Masayuki、Watanabe Tomohiro、Kamata Ken、Minaga Kosuke、Kudo Masatoshi
    • Journal Title

      Frontiers in Physiology

      Volume: 12 Pages: 781012-781012

    • DOI

      10.3389/fphys.2021.781012

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08455, KAKENHI-PROJECT-21K15987
  • [Journal Article] Plasmacytoid Dendritic Cells as a New Therapeutic Target for Autoimmune Pancreatitis and IgG4-Related Disease2021

    • Author(s)
      Minaga Kosuke、Watanabe Tomohiro、Hara Akane、Yoshikawa Tomoe、Kamata Ken、Kudo Masatoshi
    • Journal Title

      Frontiers in Immunology

      Volume: 12 Pages: 713779-713779

    • DOI

      10.3389/fimmu.2021.713779

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08455, KAKENHI-PROJECT-21K15987
  • [Journal Article] Biomarkers in autoimmune pancreatitis and immunoglobulin G4-related disease2021

    • Author(s)
      Hara Akane、Watanabe Tomohiro、Minaga Kosuke、Yoshikawa Tomoe、Kamata Ken、Kudo Masatoshi
    • Journal Title

      World Journal of Gastroenterology

      Volume: 27 Issue: 19 Pages: 2257-2269

    • DOI

      10.3748/wjg.v27.i19.2257

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K15987
  • [Journal Article] Intestinal Dysbiosis and Autoimmune Pancreatitis2021

    • Author(s)
      Yoshikawa Tomoe、Watanabe Tomohiro、Kamata Ken、Hara Akane、Minaga Kosuke、Kudo Masatoshi
    • Journal Title

      Frontiers in Immunology

      Volume: 12 Pages: 621532-621532

    • DOI

      10.3389/fimmu.2021.621532

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K15987
  • [Journal Article] A unique profile of serum cytokines in type 1 autoimmune pancreatitis and chronic rhinosinusitis2021

    • Author(s)
      Yoshikawa Tomoe、Minaga Kosuke、Hara Akane、Sekai Ikue、Otsuka Yasuo、Takada Ryutaro、Kamata Ken、Watanabe Tomohiro、Kudo Masatoshi
    • Journal Title

      Asian Pacific Journal of Allergy and Immunology

      Volume: -

    • DOI

      10.12932/ap-311020-0990

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K15987
  • [Journal Article] Improved detection of liver metastasis using Kupffer-phase imaging in contrast-enhanced harmonic EUS in patients with pancreatic cancer (with video)2021

    • Author(s)
      Minaga Kosuke、Kitano Masayuki、Nakai Atsushi、Omoto Shunsuke、Kamata Ken、Yamao Kentaro、Takenaka Mamoru、Tsurusaki Masakatsu、Chikugo Takaaki、Matsumoto Ippei、Chiba Yasutaka、Watanabe Tomohiro、Kudo Masatoshi
    • Journal Title

      Gastrointestinal Endoscopy

      Volume: 93 Issue: 2 Pages: 433-441

    • DOI

      10.1016/j.gie.2020.06.051

    • Data Source
      KAKENHI-PROJECT-19K17506
  • [Journal Article] Activation of interferon regulatory factor 7 in plasmacytoid dendritic cells promotes experimental autoimmune pancreatitis2020

    • Author(s)
      Minaga K, Watanabe T, Arai Y, Shiokawa M, Hara A, Yoshikawa T, Kamata K, Yamashita K, Kudo M
    • Journal Title

      J Gastroenterol

      Volume: - Issue: 5 Pages: 565-576

    • DOI

      10.1007/s00535-020-01662-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08455, KAKENHI-PROJECT-19K17506, KAKENHI-PROJECT-19K17828
  • [Journal Article] Gut microbiome alterations in type 1 autoimmune pancreatitis after induction of remission by prednisolone2020

    • Author(s)
      Kamata K.、Watanabe T.、Minaga K.、Hara A.、Sekai I.、Otsuka Y.、Yoshikawa T.、Park A.‐M.、Kudo M.
    • Journal Title

      Clinical & Experimental Immunology

      Volume: 202 Issue: 3 Pages: 308-320

    • DOI

      10.1111/cei.13509

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08455, KAKENHI-PROJECT-19K17506
  • [Journal Article] Identification of serum IFN-α and IL-33 as novel biomarkers for type 1 autoimmune pancreatitis and IgG4-related disease2020

    • Author(s)
      Minaga Kosuke、Watanabe Tomohiro、Hara Akane、Kamata Ken、Omoto Shunsuke、Nakai Atsushi、Otsuka Yasuo、Sekai Ikue、Yoshikawa Tomoe、Yamao Kentaro、Takenaka Mamoru、Chiba Yasutaka、Kudo Masatoshi
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 14879-14879

    • DOI

      10.1038/s41598-020-71848-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08455, KAKENHI-PROJECT-19K17506
  • [Presentation] Sympsium 47 Microbiome involved in the immunopathogenesis of autoimmune pancreatitis2023

    • Author(s)
      Kosuke Minaga
    • Organizer
      The 7th Korea Digestive Disease Week 2023
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K07450
  • [Presentation] Roles of plasmacytoid dendritic cells in the development of AIP2023

    • Author(s)
      Kosuke Minaga
    • Organizer
      55th EPC meeting in cooperation with the JPS
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K07450
  • [Presentation] 形質細胞様樹状細胞の活性化に着目したIgG4関連疾患の新たな血清バイオマーカーの同定2022

    • Author(s)
      原茜、三長孝輔、鎌田研、渡邉智裕、工藤正俊
    • Organizer
      医学生・研修医の日本内科学会ことはじめ2022
    • Data Source
      KAKENHI-PROJECT-21K15987
  • [Presentation] 自己免疫性膵炎の発症に関わるサイトカイン・ケモカインネットワークの解明と新規バイオマーカーの同定2021

    • Author(s)
      原茜、吉川智恵、三長孝輔、鎌田研、渡邉智裕、工藤正俊
    • Organizer
      第29回 若手膵臓病研究会
    • Data Source
      KAKENHI-PROJECT-21K15987
  • [Presentation] 形質細胞様樹状細胞の活性化に着目したIgG4 関連疾患のバイオマーカーの同定2020

    • Author(s)
      三長孝輔、原茜、吉川智恵、鎌田研、渡邉智裕、工藤正俊
    • Organizer
      第28回 若手膵臓研究会
    • Data Source
      KAKENHI-PROJECT-19K17506
  • [Presentation] 自己免疫性膵胆道疾患診療の課題と展望 転写因子IRF7の活性化からみた自己免疫性膵炎の病態解明2020

    • Author(s)
      三長孝輔、渡邉智裕、工藤正俊
    • Organizer
      第106回 日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-19K17506
  • [Presentation] 消化器領域から見たIgG4関連疾患研究の進歩 IRF7-I型IFN-IL-33経路がIgG4関連疾患の病態に果たす役割とバイオマーカーとしての有用性2020

    • Author(s)
      三長孝輔、渡邉智裕、工藤正俊
    • Organizer
      第62回 日本消化器病学会大会
    • Data Source
      KAKENHI-PROJECT-19K17506
  • [Presentation] 転写因子IRF7の活性化からみたIgG4関連疾患の病態解明2019

    • Author(s)
      三長孝輔、渡邉智裕、新井康之、塩川雅広、吉川智恵、鎌田研、山下浩平、工藤正俊
    • Organizer
      日本消化器免疫学会総会
    • Data Source
      KAKENHI-PROJECT-19K17506
  • [Presentation] 腸内細菌叢からみた膵酵素補充療法の慢性膵炎に対する炎症抑制機序の解明2019

    • Author(s)
      三長孝輔、渡邉智裕、工藤正俊
    • Organizer
      日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-19K17506
  • [Presentation] 血清IFN-α/IL-33が治療効果判定に有用と考えられた自己免疫性膵炎/IgG4関連疾患の1例2019

    • Author(s)
      原茜、三長孝輔、 岡本彩那、石川嶺、山崎友裕、中井敦史、大本俊介、鎌田研、山雄健太郎、竹中完、渡邉智裕、安川覚、工藤正俊
    • Organizer
      日本消化器病学会近畿支部例会
    • Data Source
      KAKENHI-PROJECT-19K17506
  • 1.  渡邉 智裕 (40444468)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 2.  KUDO Masatoshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 7 results

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