Chadani Yuhei 茶谷悠平

Researcher Number	30794383
Other IDs
Affiliation (Current)	2025: 岡山大学, 環境生命自然科学学域, 研究教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 岡山大学, 環境生命自然科学学域, 准教授 2018 – 2020: 東京工業大学, 科学技術創成研究院, 特任助教 2017: 東京工業大学, 科学技術創成研究院, 研究員
Review Section/Research Field	Principal Investigator Basic Section 43010:Molecular biology-related / Molecular biology Except Principal Investigator Transformative Research Areas, Section (III)
Keywords	Principal Investigator 翻訳 / 新生ポリペプチド鎖 / リボソーム / タンパク質合成 / 遺伝子発現制御 / 遺伝子発現 / 翻訳伸長因子 / 翻訳制御 / タンパク質機能制御 / タンパク質 … More / アイソフォーム / 非典型的翻訳 / リボソームトンネル / フレームシフト / ORF / 翻訳(タンパク質合成) / peptidyl-tRNA / 翻訳伸長 / tRNA … More Except Principal Investigator 新生ポリペプチド鎖 / 翻訳 / プロテオミクス / 翻訳バイパス / RAN翻訳 / 非典型的な翻訳 / タンパク質 / リボソーム Less

合成途上産物に秘められた拡張型遺伝情報の解読と遺伝子像の再構成Principal Investigator
- Principal Investigator
  
  茶谷悠平
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Okayama University
非典型的な翻訳動態の多様性・普遍性と分子機構
- Principal Investigator
  
  田口英樹
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Tokyo Institute of Technology
Exploration of novel protein repertoires expanded by the regulation of translation elongation dynamicsPrincipal Investigator
- Principal Investigator
  
  Chadani Yuhei
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Tokyo Institute of Technology
Study of the mechanism of nascent polypeptide-induced translation abortion.Principal Investigator
- Principal Investigator
  
  Chadani Yuhei
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Molecular biology
- Research Institution
  Tokyo Institute of Technology

All 2024 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] The ABCF proteins in <i>Escherichia coli</i> individually cope with ‘hard-to-translate’ nascent peptide sequences2024
- Author(s)
  Chadani Yuhei、Yamanouchi Shun、Uemura Eri、Yamasaki Kohei、Niwa Tatsuya、Ikeda Toma、Kurihara Miku、Iwasaki Wataru、Taguchi Hideki
- Journal Title
  
  Nucleic Acids Research
  
  Volume: － Issue: 10 Pages: 5825-5840
- DOI
  10.1093/nar/gkae309
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K27103
[Journal Article] Mechanistic dissection of premature translation termination induced by acidic residues-enriched nascent peptide2023
- Author(s)
  Chadani Yuhei、Kanamori Takashi、Niwa Tatsuya、Ichihara Kazuya、Nakayama Keiichi I.、Matsumoto Akinobu、Taguchi Hideki
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 12 Pages: 113569-113569
- DOI
  10.1016/j.celrep.2023.113569
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K27103
[Journal Article] Nascent peptide-induced translation discontinuation in eukaryotes impacts biased amino acid usage in proteomes2022
- Author(s)
  Ito Yosuke、Chadani Yuhei、Niwa Tatsuya、Yamakawa Ayako、Machida Kodai、Imataka Hiroaki、Taguchi Hideki
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 7451-7451
- DOI
  10.1038/s41467-022-35156-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-20H05925, KAKENHI-PUBLICLY-21H05727, KAKENHI-PROJECT-23K23875, KAKENHI-PROJECT-21H04763
[Journal Article] Prophage excision switches the primary ribosome rescue pathway and rescue‐associated gene regulations in Escherichia coli2022
- Author(s)
  Onodera Haruka、Niwa Tatsuya、Taguchi Hideki、Chadani Yuhei
- Journal Title
  
  Molecular Microbiology
  
  Volume: 119 Issue: 1 Pages: 44-58
- DOI
  10.1111/mmi.15003
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20H05925
[Journal Article] Shotgun Proteomics Revealed Preferential Degradation of Misfolded In Vivo Obligate GroE Substrates by Lon Protease in Escherichia coli2022
- Author(s)
  Niwa Tatsuya、Chadani Yuhei、Taguchi Hideki
- Journal Title
  
  Molecules
  
  Volume: 27 Issue: 12 Pages: 3772-3772
- DOI
  10.3390/molecules27123772
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-20H05925, KAKENHI-PROJECT-20K06519, KAKENHI-PROJECT-21H04763
[Journal Article] Nascent polypeptide within the exit tunnel stabilizes the ribosome to counteract risky translation2021
- Author(s)
  Chadani Yuhei、Sugata Nobuyuki、Niwa Tatsuya、Ito Yosuke、Iwasaki Shintaro、Taguchi Hideki
- Journal Title
  
  The EMBO Journal
  
  Volume: 40 Issue: 23 Pages: 1-13
- DOI
  10.15252/embj.2021108299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03984, KAKENHI-PROJECT-16H06276, KAKENHI-PLANNED-20H05925, KAKENHI-PROJECT-21H04763, KAKENHI-PROJECT-19K22406
[Journal Article] Escherichia coli small heat shock protein IbpA is an aggregation‐sensor that self‐regulates its own expression at posttranscriptional levels2020
- Author(s)
  Miwa Tsukumi、Chadani Yuhei、Taguchi Hideki
- Journal Title
  
  Molecular Microbiology
  
  Volume: 115 Issue: 1 Pages: 142-156
- DOI
  10.1111/mmi.14606
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20H05925, KAKENHI-PROJECT-18H03984
[Journal Article] 翻訳伸長ダイナミクスと新生鎖フォールディング2019
- Author(s)
  田口英樹、茶谷悠平、丹羽達也
- Journal Title
  
  生物物理
  
  Volume: 59 Pages: 137-140
- NAID
  130007653151
- Data Source
  KAKENHI-PROJECT-19K16038
[Journal Article] 翻訳伸長ダイナミクスと新生鎖フォールディング2019
- Author(s)
  田口英樹、茶谷悠平、丹羽達也
- Journal Title
  
  生物物理
  
  Volume: 59
- NAID
  130007653151
- Data Source
  KAKENHI-PROJECT-17K15062
[Journal Article] 終止コドンに依らず翻訳を途中終了させる酸性アミノ酸の連続配列2018
- Author(s)
  田口英樹、茶谷悠平、千葉志信、伊藤維昭
- Journal Title
  
  バイオサイエンスとインダストリー
  
  Volume: 76 Pages: 239-241
- NAID
  40021578678
- Data Source
  KAKENHI-PROJECT-17K15062
[Journal Article] 翻訳途上の新生ポリペプチド鎖が引き起こすリボソームの不安定化とその生理的意義2018
- Author(s)
  茶谷悠平、千葉志信、伊藤維昭、田口英樹
- Journal Title
  
  実験医学
  
  Volume: 36 Pages: 1364-1367
- Data Source
  KAKENHI-PROJECT-17K15062
[Journal Article] Intrinsic Ribosome Destabilization Underlies Translation and Provides an Organism with a Strategy of Environmental Sensing2017
- Author(s)
  Chadani Yuhei、Niwa Tatsuya、Izumi Takashi、Sugata Nobuyuki、Nagao Asuteka、Suzuki Tsutomu、Chiba Shinobu、Ito Koreaki、Taguchi Hideki
- Journal Title
  
  Molecular Cell
  
  Volume: 68 Issue: 3 Pages: 528-539
- DOI
  10.1016/j.molcel.2017.10.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15062, KAKENHI-PLANNED-26116002, KAKENHI-PLANNED-26116008, KAKENHI-PROJECT-26220205, KAKENHI-PROJECT-16H04788, KAKENHI-PLANNED-26113003
[Presentation] 蛋白質の合成過程に潜む途上終結リスクは生物のプロテオームに配列的制約をもたらす2023
- Author(s)
  茶谷　悠平
- Organizer
  第23回日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27103
[Presentation] タンパク質の安定的発現を保証する「タンパク質」の解析2023
- Author(s)
  茶谷　悠平
- Organizer
  第95回日本遺伝学会大会
- Data Source
  KAKENHI-PROJECT-23K27103
[Presentation] 遺伝情報を拡張、再定義する非典型的翻訳の再構成2022
- Author(s)
  茶谷悠平、田口英樹
- Organizer
  第18回大腸菌研究会
- Invited
- Data Source
  KAKENHI-PLANNED-20H05925
[Presentation] Nascent　peptide-induced translation discontinuation in eukaryotes impacts biased amino acid usage in proteomes2022
- Author(s)
  茶谷悠平、田口英樹
- Organizer
  第23回日本RNA学会年会
- Invited
- Data Source
  KAKENHI-PLANNED-20H05925
[Presentation] 負電荷アミノ酸クラスターの翻訳による確率的途上終結の分子メカニズム2022
- Author(s)
  茶谷悠平、田口英樹
- Organizer
  第17回無細胞生命科学研究会
- Invited
- Data Source
  KAKENHI-PLANNED-20H05925
[Presentation] Nascent polypeptide within the tunnel stabilizes the ribosome　to counteract risky translation2022
- Author(s)
  Yuhei Chadani
- Organizer
  Protein Folding on the Ribosome 2022
- Invited
- Data Source
  KAKENHI-PLANNED-20H05925
[Presentation] 翻訳停滞とリボソーム不安定化による非典型的翻訳の駆動と再構成2022
- Author(s)
  茶谷悠平、田口英樹
- Organizer
  第22回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-20H05925
[Presentation] 翻訳伸長複合体による細胞内Mg2+濃度感知と恒常性維持機構2020
- Author(s)
  茶谷悠平、丹羽達也、和泉貴士、菅田信幸、長尾翌手可、鈴木勉、千葉志信、伊藤維昭、田口英樹
- Organizer
  第 93 回日本細菌学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16038
[Presentation] タンパク質合成の連続性はリボソームトンネル内の新生ポリペプチド鎖自身によって保証される2020
- Author(s)
  茶谷悠平、菅田信幸、丹羽達也、伊藤遥介、田口英樹
- Organizer
  第 93 回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16038
[Presentation] Intrinsic Ribosome Destabilization Underlies Translation and Provides an Organism with a Strategy of Environmental Sensing.2019
- Author(s)
  Yuhei Chadani, Tatsuya Niwa, Takashi Izumi, Nobuyuki Sugata, Asuteka Nagao, Tsutomu Suzuki, Shinobu Chiba, Koreaki Ito and Hideki Taguchi
- Organizer
  Ribosome meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15062
[Presentation] リボソーム不安定化をトリガーとしたribosome hoppingによる大腸菌ORFの再定義2019
- Author(s)
  田邉葵、茶谷悠平、丹羽達也、田口英樹
- Organizer
  日本遺伝学会第91回大会
- Data Source
  KAKENHI-PROJECT-19K16038
[Presentation] Widespread nascent chain-mediated translational pausing and intrinsic ribosome destabilization2017
- Author(s)
  Yuhei Chadani, Tatsuya Niwa, Takashi Izumi, Nobuyuki Sugata, Asuteka Nagao, Tsutomu Suzuki, Shinobu Chiba, Koreaki Ito and Hideki Taguchi
- Organizer
  第69回日本細胞生物学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K15062

1. 田口英樹 (40272710)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results

Chadani Yuhei 茶谷 悠平

Research Projects

Research Products

Co-Researchers

合成途上産物に秘められた拡張型遺伝情報の解読と遺伝子像の再構成Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

非典型的な翻訳動態の多様性・普遍性と分子機構

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exploration of novel protein repertoires expanded by the regulation of translation elongation dynamicsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study of the mechanism of nascent polypeptide-induced translation abortion.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The ABCF proteins in <i>Escherichia coli</i> individually cope with ‘hard-to-translate’ nascent peptide sequences2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mechanistic dissection of premature translation termination induced by acidic residues-enriched nascent peptide2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nascent peptide-induced translation discontinuation in eukaryotes impacts biased amino acid usage in proteomes2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prophage excision switches the primary ribosome rescue pathway and rescue‐associated gene regulations in Escherichia coli2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Shotgun Proteomics Revealed Preferential Degradation of Misfolded In Vivo Obligate GroE Substrates by Lon Protease in Escherichia coli2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nascent polypeptide within the exit tunnel stabilizes the ribosome to counteract risky translation2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Escherichia coli small heat shock protein IbpA is an aggregation‐sensor that self‐regulates its own expression at posttranscriptional levels2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 翻訳伸長ダイナミクスと新生鎖フォールディング2019

Author(s)

Journal Title

NAID

Data Source

[Journal Article] 翻訳伸長ダイナミクスと新生鎖フォールディング2019

Author(s)

Journal Title

NAID

Data Source

[Journal Article] 終止コドンに依らず翻訳を途中終了させる酸性アミノ酸の連続配列2018

Author(s)

Journal Title

NAID

Data Source

[Journal Article] 翻訳途上の新生ポリペプチド鎖が引き起こすリボソームの不安定化とその生理的意義2018

Author(s)

Chadani Yuhei 茶谷悠平

[Presentation] 蛋白質の合成過程に潜む途上終結リスクは生物のプロテオームに配列的制約をもたらす2023

[Presentation] Nascent　peptide-induced translation discontinuation in eukaryotes impacts biased amino acid usage in proteomes2022

[Presentation] Nascent polypeptide within the tunnel stabilizes the ribosome　to counteract risky translation2022