Tazawa Kento 田澤建人

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田澤建人タザワケント

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Researcher Number	30801518
Other IDs
Affiliation (Current)	2025: 東京科学大学, 東京科学大学病院, 助教
Affiliation (based on the past Project Information) *help	2023: 東京医科歯科大学, 東京医科歯科大学病院, 助教 2022: 東京医科歯科大学, 大学院医歯学総合研究科, 助教 2019 – 2020: 東京医科歯科大学, 大学院医歯学総合研究科, 助教 2018: 東京医科歯科大学, 歯学部附属病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 57030:Conservative dentistry-related
Keywords	Principal Investigator whole mount staining / single cell 解析 / NGS解析 / 歯髄マクロファージ / 疼痛 / 歯髄幹細胞 / 象牙芽細胞 / ヒト歯髄細胞 / マクロファージ / Lyve1 … More / TRPA1 / 歯髄 / 石灰化 / P38 / NO / LPS / 歯髄細胞 / TRPチャネル Less

3D動態解析とシングルセル解析を用いた歯髄マクロファージ機能の解明Principal Investigator
- Principal Investigator
  
  田澤建人
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Tokyo Medical and Dental University
冷痛覚過敏の治療ターゲットとして展開する炎症時TRPA1チャネルの動態解析Principal Investigator
- Principal Investigator
  
  田澤建人
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Tokyo Medical and Dental University

All 2022 2020 2019 2018

All Journal Article Presentation

[Journal Article] Kinetics of LYVE-1-positive M2-like macrophages in developing and repairing dental pulp in vivo and their pro-angiogenic activity in vitro2022
- Author(s)
  Kieu Thoai Quoc、Tazawa Kento、Kawashima Nobuyuki、Noda Sonoko、Fujii Mayuko、Nara Keisuke、Hashimoto Kentaro、Han Peifeng、Okiji Takashi
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 5176-5176
- DOI
  10.1038/s41598-022-08987-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09870, KAKENHI-PROJECT-18K17039, KAKENHI-PROJECT-21K16989
[Journal Article] 6.Hypoxia-inducible factor 1α promotes interleukin 1β and tumour necrosis factor α expression in lipopolysaccharide-stimulated human dental pulp cells2020
- Author(s)
  Fujii M, Kawashima N, Tazawa K, Hashimoto K, Nara K, Noda S, Nagai S, Okiji T
- Journal Title
  
  International Endodontic Journal.
  
  Volume: 53 Issue: 5 Pages: 636-646
- DOI
  10.1111/iej.13264
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K17039, KAKENHI-PROJECT-19K24137, KAKENHI-PROJECT-17H04376, KAKENHI-PROJECT-17H04380
[Journal Article] Transient Receptor Potential Ankyrin 1 Is Up-Regulated in Response to Lipopolysaccharide via P38/Mitogen-Activated Protein Kinase in Dental Pulp Cells and Promotes Mineralization2020
- Author(s)
  Tazawa K, Kawashima N, Kuramoto M, Noda S, Fujii M, Nara K, Hashimoto K, Okiji T
- Journal Title
  
  The American journal of pathology
  
  Volume: - Issue: 12 Pages: 2417-2426
- DOI
  10.1016/j.ajpath.2020.08.016
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K17039
[Journal Article] 5.HIF1α inhibits LPS-mediated induction of IL-6 synthesis via SOCS3-dependent CEBPβ suppression in human dental pulp cells2020
- Author(s)
  Mayuko Fujii; Kento Tazawa; Kentaro Hashimoto; Keisuke Nara; Sonoko Noda; Masashi Kuramoto; Shion Orikasa; Shigenori Nagai; Takashi Okiji
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 522 Issue: 2 Pages: 308-314
- DOI
  10.1016/j.bbrc.2019.11.032
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K17039, KAKENHI-PROJECT-17H04376, KAKENHI-PROJECT-17H04380, KAKENHI-PROJECT-19K24137
[Journal Article] 4.Anti-inflammatory roles of microRNA 21 in lipopolysaccharide-stimulated human dental pulp cells2019
- Author(s)
  Nara K, Kawashima N, Noda S, Fujii M, Hashimoto K, Tazawa K, Okiji T
- Journal Title
  
  J Cell Physiol
  
  Volume: 234 Issue: 11 Pages: 21331-21341
- DOI
  10.1002/jcp.28737
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K17039, KAKENHI-PROJECT-17H04380
[Journal Article] LYVE-1-expressing macrophages co-express CD163 in rat normal dental pulp tissue2019
- Author(s)
  田澤建人，川島伸之，草野雅彦，池田英治，興地隆
- Journal Title
  
  The Journal of Japan Endodontic Association
  
  Volume: 40 Issue: 1 Pages: 7-13
- DOI
  10.20817/jeajournal.40.1_7
- NAID
  130007594626
- ISSN
  1347-8672, 2423-9429
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K17039, KAKENHI-PROJECT-16K15794
[Presentation] 1.TRPA1 is upregulated in response to LPS via p38/MAPK and promotes mineralization in dental pulp cells.2020
- Author(s)
  Tazawa Kento, Kawashima Nobuyuki, Kuramoto Masashi, Nara Keisuke, Fujii Mayuko, Noda Sonoko, Hashimoto Kentaro, Okiji Takashi.
- Organizer
  2019年度バランスユニット若手ワークショップ
- Data Source
  KAKENHI-PROJECT-18K17039
[Presentation] 2.TRPA1 is upregulated in response to LPS via P38/MAPK and promotes mineralization in dental pulp cells.2019
- Author(s)
  田澤建人, 川島伸之, 興地隆史
- Organizer
  第84回口腔病学会学術大会
- Data Source
  KAKENHI-PROJECT-18K17039
[Presentation] ラット正常歯髄組織においてLYVE-1陽性細胞はCD163を発現する2018
- Author(s)
  田澤建人、川島伸之、池田英治、興地隆史
- Organizer
  日本歯内療法学会学術大会
- Data Source
  KAKENHI-PROJECT-18K17039
[Presentation] LPS刺激ヒト歯髄細胞におけるTRPA1の発現はNO/p38 MAPKシグナルにより誘導される2018
- Author(s)
  田澤　建人, 川島　伸之, 倉本　将司,　奈良　圭介, 野田　園子, 藤井　真由子, 橋本　健太郎, 興地　隆史
- Organizer
  日本歯科保存学会
- Data Source
  KAKENHI-PROJECT-18K17039

1. 川島伸之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 興地隆史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tazawa Kento 田澤 建人

田澤 建人 タザワ ケント

Research Projects

Research Products

Co-Researchers

3D動態解析とシングルセル解析を用いた歯髄マクロファージ機能の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

冷痛覚過敏の治療ターゲットとして展開する炎症時TRPA1チャネルの動態解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Kinetics of LYVE-1-positive M2-like macrophages in developing and repairing dental pulp in vivo and their pro-angiogenic activity in vitro2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 6.Hypoxia-inducible factor 1α promotes interleukin 1β and tumour necrosis factor α expression in lipopolysaccharide-stimulated human dental pulp cells2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Transient Receptor Potential Ankyrin 1 Is Up-Regulated in Response to Lipopolysaccharide via P38/Mitogen-Activated Protein Kinase in Dental Pulp Cells and Promotes Mineralization2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 5.HIF1α inhibits LPS-mediated induction of IL-6 synthesis via SOCS3-dependent CEBPβ suppression in human dental pulp cells2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 4.Anti-inflammatory roles of microRNA 21 in lipopolysaccharide-stimulated human dental pulp cells2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] LYVE-1-expressing macrophages co-express CD163 in rat normal dental pulp tissue2019

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Presentation] 1.TRPA1 is upregulated in response to LPS via p38/MAPK and promotes mineralization in dental pulp cells.2020

Author(s)

Organizer

Data Source

[Presentation] 2.TRPA1 is upregulated in response to LPS via P38/MAPK and promotes mineralization in dental pulp cells.2019

Author(s)

Organizer

Data Source

[Presentation] ラット正常歯髄組織においてLYVE-1陽性細胞はCD163を発現する2018

Author(s)

Organizer

Data Source

[Presentation] LPS刺激ヒト歯髄細胞におけるTRPA1の発現はNO/p38 MAPKシグナルにより誘導される2018

Author(s)

Organizer

Data Source

Tazawa Kento 田澤建人

田澤建人タザワケント