Inoue Satoshi 井上聡

Researcher Number	30801930
Affiliation (Current)	2025: 慶應義塾大学, 医学部(信濃町), 講師
Affiliation (based on the past Project Information) *help	2023 – 2025: 慶應義塾大学, 医学部(信濃町), 講師 2021 – 2022: 愛知県がんセンター(研究所), 腫瘍免疫応答研究分野, ユニット長 2019 – 2020: 国立研究開発法人国立がん研究センター, 研究所, 特任研究員
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Medium-sized Section 50:Oncology and related fields / Basic Section 50020:Tumor diagnostics and therapeutics-related Except Principal Investigator Basic Section 56040:Obstetrics and gynecology-related
Keywords	Principal Investigator ゲノム異常 / CAR-T細胞 / 細胞免疫治療 / 個別化医療 / がん免疫 / クローン性造血 / クローン造血 / CAR=T細胞 / 加齢 / レーザーマイクロダイセクション … More / プロゲステロン受容体 / KRAS / 妊娠 / 分娩 / LCM / FFPE / ゲノム解析 / 子宮内膜 / 子宮内膜症 / 子宮腺筋症 … More Except Principal Investigator 免疫トレランス / 腫瘍微小環境 / メソセリン / キメラ抗原受容体 Less

腹膜播種におけるCAR-T細胞疲弊の克服と複合的免疫治療への応用
- Principal Investigator
  
  芳川修久
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Nagoya University
Utilizing ageing-related clonal haematopoesisfor effective CAR-T cell therapyPrincipal Investigator
- Principal Investigator
  
  Inoue Satoshi
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Keio University
  Aichi Cancer Center Research Institute
Identification of resistant mechanisms of tumor cells against CAR-T cell-mediated cytotoxicityPrincipal Investigator
- Principal Investigator
  
  井上聡
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Keio University
  Aichi Cancer Center Research Institute
Establishment of effective and reliable detection system for genomic alterations in uterine adenomyosisPrincipal Investigator
- Principal Investigator
  
  Inoue Satoshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Aichi Cancer Center Research Institute
  National Cancer Center Japan

All 2024 2023 2022 2021 2020 2019

All Journal Article

[Journal Article] Development of a chimeric cytokine receptor that captures IL-6 and enhances the antitumor response of CAR-T cells2024
- Author(s)
  Yoshikawa Toshiaki、Ito Yusuke、Wu Zhiwen、Kasuya Hitomi、Nakashima Takahiro、Okamoto Sachiko、Amaishi Yasunori、Zhang Haosong、Li Yang、Matsukawa Tetsuya、Inoue Satoshi、Kagoya Yuki
- Journal Title
  
  Cell Reports Medicine
  
  Volume: Apr 16 Issue: 5 Pages: 101526-101526
- DOI
  10.1016/j.xcrm.2024.101526
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06710, KAKENHI-PROJECT-22K15575, KAKENHI-PROJECT-23K24171
[Journal Article] Gene editing technology to improve antitumor T-cell functions in adoptive immunotherapy2024
- Author(s)
  Ito Y, Inoue S, Kagoya Y.
- Journal Title
  
  Inflamm Regen .
  
  Volume: 44 Issue: 1 Pages: 13-13
- DOI
  10.1186/s41232-024-00324-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19474, KAKENHI-PROJECT-23K24171, KAKENHI-PROJECT-23K27470
[Journal Article] High CD62L expression predicts the generation of chimeric antigen receptor T cells with potent effector functions2024
- Author(s)
  Kasuya H, Zhang H, Ito Y, Yoshikawa T, Nakashima T, Li Y, Matsukawa T, Inoue S, Kagoya Y
- Journal Title
  
  Int Immunol .
  
  Volume: ー Issue: 7 Pages: 353-364
- DOI
  10.1093/intimm/dxae015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19474, KAKENHI-PROJECT-23K24171
[Journal Article] CD83 expression characterizes precursor exhausted T cell population2023
- Author(s)
  Wu Zhiwen、Yoshikawa Toshiaki、Inoue Satoshi、Ito Yusuke、Kasuya Hitomi、Nakashima Takahiro、Zhang Haosong、Kotaka Saki、Hosoda Waki、Suzuki Shiro、Kagoya Yuki
- Journal Title
  
  Communications Biology
  
  Volume: 6 Issue: 1 Pages: 258-258
- DOI
  10.1038/s42003-023-04631-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03543, KAKENHI-PROJECT-23K24171, KAKENHI-PROJECT-23K14554, KAKENHI-PROJECT-22K19474
[Journal Article] Epigenetic profiles guide improved CRISPR/Cas9-mediated gene knockout in human T cells2023
- Author(s)
  Ito Yusuke、Inoue Satoshi、Nakashima Takahiro、Zhang Haosong、Li Yang、Kasuya Hitomi、Matsukawa Tetsuya、Wu Zhiwen、Yoshikawa Toshiaki、Kataoka Mirei、Ishikawa Tetsuo、Kagoya Yuki
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 52 Issue: 1 Pages: 141-153
- DOI
  10.1093/nar/gkad1076
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21837, KAKENHI-PROJECT-21K02356, KAKENHI-PROJECT-22K19474, KAKENHI-PROJECT-23K24171, KAKENHI-PROJECT-23K27470
[Journal Article] Genetic ablation of PRDM1 in antitumor T cells enhances therapeutic efficacy of adoptive immunotherapy2022
- Author(s)
  Toshiaki Yoshikawa, Zhiwen Wu, Satoshi Inoue, Hitomi Kasuya, Hirokazu Matsushita, Yusuke Takahashi, Hiroaki Kuroda, Waki Hosoda, Shiro Suzuki, Yuki Kagoya
- Journal Title
  
  Blood
  
  Volume: 139 Issue: 14 Pages: 2156
- DOI
  10.1182/blood.2021012714
- URL
  https://pure.teikyo.jp/en/publications/6a2b019c-e097-4984-a55e-185c8e982370
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09297, KAKENHI-PROJECT-19H03528, KAKENHI-PROJECT-22K19474, KAKENHI-PROJECT-20H03543, KAKENHI-PROJECT-21K19422, KAKENHI-PROJECT-23K24171
[Journal Article] MicroSEC; Sequence error filtering pipeline for formalin-fixed and paraffin-embedded samples.2021
- Author(s)
  Ikegami M, Kohsaka S, Hirose T, Ueno T, Inoue S, Konomata N, Yamauchi H, Mori T, Sekine S, Inamoto Y, Yatabe Y, Kobayashi H, Tanaka S, Mano H.
- Journal Title
  
  Commun Biol
  
  Volume: 4 Issue: 1 Pages: 1396-1396
- DOI
  10.1038/s42003-021-02930-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07708, KAKENHI-PROJECT-20H03461, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-20K07383, KAKENHI-PROJECT-20K09453, KAKENHI-PROJECT-21K12117
[Journal Article] High-throughput functional evaluation of BRCA2 variants of unknown significance.2020
- Author(s)
  Ikegami, M., Kohsaka, S., Ueno, T., Momozawa, Y., Inoue, S., Tamura, K., Shimomura, A., Hosoya, N., Kobayashi, H., Tanaka, S., Mano, H.
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 2573-2573
- DOI
  10.1038/s41467-020-16141-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07708, KAKENHI-PROJECT-20K08127, KAKENHI-PROJECT-20K09453, KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-19J13207
[Journal Article] KRAS mutations in uterine endometrium are associated with gravidity and parity.2020
- Author(s)
  Inoue, S., Yoshida, E., Fukui, Y., Ueno, T., Kawazu, M., Takeyama, R., Ikemura, M., Osuga, Y., Terao, Y., Hirota, Y., Mano, H.
- Journal Title
  
  Cell Death Disease
  
  Volume: 11 Issue: 5 Pages: 347-347
- DOI
  10.1038/s41419-020-2559-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07708, KAKENHI-PROJECT-19H03796, KAKENHI-PROJECT-18K07320, KAKENHI-PROJECT-19H03144
[Journal Article] Differential regulation of CpG island methylation within divergent and unidirectional promoters in colorectal cancer2019
- Author(s)
  Namba Shinichi、Sato Kazuhito、Kojima Shinya、Ueno Toshihide、Yamamoto Yoko、Tanaka Yosuke、Inoue Satoshi、Nagae Genta、Iinuma Hisae、Hazama Shoichi、Ishihara Soichiro、Aburatani Hiroyuki、Mano Hiroyuki、Kawazu Masahito
- Journal Title
  
  Cancer Science
  
  Volume: 110 Issue: 3 Pages: 1096-1104
- DOI
  10.1111/cas.13937
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07250, KAKENHI-PROJECT-18K07963, KAKENHI-PROJECT-18K08716, KAKENHI-PROJECT-17J00386, KAKENHI-PROJECT-15K08987, KAKENHI-PROJECT-16K07143, KAKENHI-PROJECT-18K07320, KAKENHI-PROJECT-19K07708
[Journal Article] Uterine adenomyosis is an oligoclonal disorder associated with KRAS mutations2019
- Author(s)
  Inoue Satoshi、Hirota Yasushi、Ueno Toshihide、十人省略、Tanaka Yosuke、Sakata Seiji、Takeuchi Kengo、Muraoka Ayako、Osuka Satoko、Saito Tsuyoshi、Oda Katsutoshi、Osuga Yutaka、Terao Yasuhisa、Kawazu Masahito、Mano Hiroyuki
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 1-13
- DOI
  10.1038/s41467-019-13708-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07320, KAKENHI-PROJECT-18K09249, KAKENHI-PROJECT-19K07708, KAKENHI-PROJECT-19H03796, KAKENHI-PROJECT-17K07250, KAKENHI-PROJECT-18K19601, KAKENHI-PROJECT-18K16757, KAKENHI-PROJECT-16H04679, KAKENHI-PROJECT-16H05469, KAKENHI-PROJECT-19H03144, KAKENHI-PROJECT-19K22670

1. 松下博和 (80597782)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 芳川修久 (60804747)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 中村香江 (10744047)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 上野敏秀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 籠谷勇紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 石川哲朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 吉川聡明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 河津正人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Inoue Satoshi 井上 聡

Research Projects

Research Products

Co-Researchers

腹膜播種におけるCAR-T細胞疲弊の克服と複合的免疫治療への応用

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Utilizing ageing-related clonal haematopoesisfor effective CAR-T cell therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of resistant mechanisms of tumor cells against CAR-T cell-mediated cytotoxicityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of effective and reliable detection system for genomic alterations in uterine adenomyosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Development of a chimeric cytokine receptor that captures IL-6 and enhances the antitumor response of CAR-T cells2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gene editing technology to improve antitumor T-cell functions in adoptive immunotherapy2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] High CD62L expression predicts the generation of chimeric antigen receptor T cells with potent effector functions2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CD83 expression characterizes precursor exhausted T cell population2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Epigenetic profiles guide improved CRISPR/Cas9-mediated gene knockout in human T cells2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genetic ablation of PRDM1 in antitumor T cells enhances therapeutic efficacy of adoptive immunotherapy2022

Author(s)

Journal Title

DOI

URL

Language

Data Source

[Journal Article] MicroSEC; Sequence error filtering pipeline for formalin-fixed and paraffin-embedded samples.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] High-throughput functional evaluation of BRCA2 variants of unknown significance.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] KRAS mutations in uterine endometrium are associated with gravidity and parity.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Differential regulation of CpG island methylation within divergent and unidirectional promoters in colorectal cancer2019

Author(s)

Journal Title

DOI

Data Source

Inoue Satoshi 井上聡